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How to get fromCape Cod to Florenceby bus, plane, train, bus (Flixbus), car or bus (Greyhound)

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There are 10 ways to get from Cape Cod to Florence by bus, plane, train, bus (Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Boston Logan Airport, fly to Myrtle Beach, bus

    best
    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Myrtle Beach (MYR)plane plane BOS - MYR
    3. Take the bus from Myrtle Beach, SC to Florencebus bus
    9h 6m
    $115–361

  2. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Florence Stationtrain train
    20h 20m
    $180–1,038

  3. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to New York City Chinatownbus bus
    3. Take the bus from New York, NY to Florence, SCbus bus Nyc
    21h 49m
    $150–218

  4. Drive 871.1 mi

    1. Drive from Cape Cod to Florencecar car 871.1 mi
    15h 58m
    $159–230

  5. Bus to Boston Logan Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Charlotte Douglas International Airport (CLT)plane plane BOS - CLT
    3. Take the bus from Charlotte Bus Station to Florence Bus Stationbus bus
    10h 30m
    $153–426

  6. Bus to Boston Logan Airport, fly to Wilmington International Airport, bus

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Wilmington International Airport (ILM)plane plane BOS - ILM
    3. Take the bus from Wilmington Cape Fear Public Transit to Lumbertonbus bus
    4. Take the bus from Lumberton to Florencebus bus
    11h 7m
    $219–695

  7. Bus to Boston Logan Airport, fly to Charleston International Airport, train

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Charleston International Airport (CHS)plane plane BOS - CHS
    3. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    11h 31m
    $189–487

  8. Bus, train to Theodore Francis Green State Airport, fly to Myrtle Beach

    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus bus
    2. Take the train from South Station to TF Green Airporttrain train
    3. Fly from Theodore Francis Green State Airport (PVD) to Myrtle Beach (MYR)plane plane PVD - MYR
    4. Take the bus from Myrtle Beach, SC to Florencebus bus
    11h 25m
    $243–647

  9. Bus to Boston Logan Airport, fly to Raleigh-Durham International Airport, bus

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Raleigh-Durham International Airport (RDU)plane plane BOS - RDU
    3. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    12h 3m
    $189–538

  10. Bus via Raleigh

    1. Take the bus from Hyannis Transportation Center to Providence Bus Terminalbus bus
    2. Take the bus from Peter Pan Bus Terminal to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Raleigh Bus Stationbus bus
    4. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    22h 34m
    $125–248

Cape Cod to Florence by bus and train

Calendar14Weekly Services
Duration20h 20mAverage Duration
Ticket$180Cheapest Price
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Questions & Answers

What companies run services between Cape Cod, MA, USA and Florence, SC, USA?

You can take a bus from Town Hall Lawton Bus Shelter to Florence, SC via Hyannis Transportation Center, Boston, Bus Terminal South Station, Boston, New York City Chinatown, and New York, NY in around 21h 49m.

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