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How to get fromCape Cod to Charlestonby bus, plane, train or car

Find Transport to Charleston

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There are 9 ways to get from Cape Cod to Charleston by bus, plane, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Boston Logan Airport, fly to Charleston International Airport

    best
    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Charleston International Airport (CHS)plane plane BOS - CHS
    8h 19m
    $163–495

  2. Fly Barnstable Municipal Airport to Charleston International Airport

    cheapest
    1. Fly from Barnstable Municipal Airport (HYA) to Charleston International Airport (CHS)plane plane HYA - CHS
    8h 42m
    $108–558

  3. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain train
    22h 16m
    $208–1,170

  4. Drive 972.1 mi

    1. Drive from Cape Cod to Charlestoncar car 972.1 mi
    18h 32m
    $178–257

  5. Bus, train to Theodore Francis Green State Airport, fly to Charleston International Airport

    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus bus
    2. Take the train from South Station to TF Green Airporttrain train
    3. Fly from Theodore Francis Green State Airport (PVD) to Charleston International Airport (CHS)plane plane PVD - CHS
    10h 34m
    $111–551

  6. Bus to Boston Logan Airport, fly to Myrtle Beach, bus

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Myrtle Beach (MYR)plane plane BOS - MYR
    3. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    11h 49m
    $111–370

  7. Bus, train via Washington

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Washington Union Stationtrain train
    3. Take the train from Washington Union Station to Charleston Amtrak Stationtrain train
    22h 39m
    $204–1,202

  8. Bus, train via Philadelphia

    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus bus
    2. Take the train from Boston to 30th Street Stationtrain train
    3. Take the train from 30th Street Station to Charleston Amtrak Stationtrain train
    23h 24m
    $202–1,167

  9. Bus, train via N. Charleston SuperStop

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain train
    24h 18m
    $218–457

Cape Cod to Charleston by bus and train

Calendar14Weekly Services
Duration22h 39mAverage Duration
Ticket$204Cheapest Price
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Questions & Answers

What companies run services between Cape Cod, MA, USA and Charleston, SC, USA?

American Airlines, JetBlue Airways, and two other airlines fly from Barnstable Municipal Airport (HYA) to Charleston International Airport (CHS) 3 times a day.

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