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How to get fromCape Cod to Buffaloby taxi, plane, bus (Greyhound), bus, train, car or bus (Flixbus)

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There are 7 ways to get from Cape Cod to Buffalo by taxi, plane, bus (Greyhound), bus, train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Provincetown Municipal Airport, fly

    best
    1. Take the taxi from Cape Cod to Provincetown Municipal Airport (PVC)taxi taxi
    2. Fly from Provincetown Municipal Airport (PVC) to Buffalo Niagara International Airport (BUF)plane plane PVC - BUF
    7h 7m
    $547–1,442

  2. Bus

    cheapest
    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus bus Hyannis
    2. Take the bus from Boston to Buffalobus bus Greyhound US0171
    13h 59m
    $92–188

  3. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus Hyannis - South Shore to Logan Airport
    2. Take the train from Boston to Buffalo Depew Stationtrain train Lake Shore Limited
    17h 10m
    $164–332

  4. Drive 517.1 mi

    1. Drive from Cape Cod to Buffalocar car 517.1 mi
    9h 8m
    $95–137

  5. Fly from Barnstable Municipal Airport

    1. Fly from Barnstable Municipal Airport (HYA) to Buffalo Niagara International Airport (BUF)plane plane HYA - BUF
    7h 57m
    $241–1,434

  6. Bus to Boston Logan Airport, fly

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    6h 44m
    $166–971

  7. Bus via Ithaca

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Ithacabus bus
    3. Take the bus from Ithaca to Buffalobus bus
    16h 13m
    $103–223

Cape Cod to Buffalo by bus

Calendar7Weekly Buses
Duration13h 59mAverage Duration
Ticket$92Cheapest Price
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Questions & Answers

What companies run services between Cape Cod, MA, USA and Buffalo, NY, USA?

You can take a bus from Town Hall Lawton Bus Shelter to Buffalo via Hyannis Transportation Center, Boston South Station, and Boston in around 13h 59m. Alternatively, Cape Air, JetBlue Airways, and American Airlines fly from Barnstable Municipal Airport (HYA) to Buffalo Niagara International Airport (BUF) 5 times a day.

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