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How to get fromCape Cod to Buffaloby taxi, plane, bus (Greyhound), bus, train, car, or bus (Flixbus)

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There are 8 ways to get from Cape Cod to Buffalo by taxi, plane, bus (Greyhound), bus, train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Provincetown Municipal Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the taxi from Cape Cod to Provincetown Municipal Airport (PVC)taxi taxi
    2. Fly from Provincetown Municipal Airport (PVC) to Buffalo Niagara International Airport (BUF)plane plane PVC - BUF
    5h 45m
    $263–883

  2. Drive  517.1 mi

    cheapest
    1. Drive from Cape Cod to Buffalocar car 517.1 mi
    9h 8m
    $95–137

  3. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus Hyannis - South Shore to Logan Airport
    2. Take the bus from Boston to Buffalobus bus Greyhound US0171
    13h 31m
    $102–155

  4. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus Hyannis - South Shore to Logan Airport
    2. Take the train from Boston to Buffalo Depew Stationtrain train Lake Shore Limited
    16h 26m
    $149–465

  5. Bus to Boston Logan Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    6h 30m
    $109–593

  6. Fly Barnstable Municipal Airport to Buffalo Niagara International Airport

    1. Fly from Barnstable Municipal Airport (HYA) to Buffalo Niagara International Airport (BUF)plane plane HYA - BUF
    7h 4m
    $97–604

  7. Bus to Boston Logan Airport, fly to Rochester, bus

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 54m
    $152–731

  8. Bus via Ithaca

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Ithacabus bus
    3. Take the bus from Ithaca to Buffalobus bus
    16h
    $107–165

Cape Cod to Buffalo by bus

Calendar7Weekly Buses
Duration13h 31mAverage Duration
Ticket$102Cheapest Price
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Questions & Answers

Map of how to get from Cape Cod to Buffalo.ExpandLaunch map view
  • Distance: 491.7 mi
  • Duration: 5h 45m

What companies run services between Cape Cod, MA, USA and Buffalo, NY, USA?

You can take a bus from Town Hall Lawton Bus Shelter to Buffalo via Hyannis Transportation Center, Boston, South Station, and Boston in around 13h 31m. Alternatively, Cape Air and JetBlue Airways fly from Barnstable Municipal Airport (HYA) to Buffalo Niagara International Airport (BUF) 3 times a day.

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