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How to get fromCape Cod to Buffaloby taxi, plane, bus (Greyhound, Flixbus), bus, train or car

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There are 6 ways to get from Cape Cod to Buffalo by taxi, plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Provincetown Municipal Airport, fly

    best
    1. Take the taxi from Cape Cod to Provincetown Municipal Airport (PVC)taxi taxi
    2. Fly from Provincetown Municipal Airport (PVC) to Buffalo Niagara International Airport (BUF)plane plane PVC - BUF
    7h 10m
    $536–1,444

  2. Drive 517.1 mi

    cheapest
    1. Drive from Cape Cod to Buffalocar car 517.1 mi
    9h 8m
    $95–137

  3. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Syracuse Bus Stationbus bus
    3. Take the bus from Syracuse Bus Station to Buffalobus bus
    14h 9m
    $101–188

  4. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus Hyannis - South Shore to Logan Airport
    2. Take the train from Boston to Buffalo Depew Stationtrain train Lake Shore Limited
    17h 9m
    $124–462

  5. Bus to Boston Logan Airport, fly

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    7h
    $165–1,023

  6. Fly from Barnstable Municipal Airport

    1. Fly from Barnstable Municipal Airport (HYA) to Buffalo Niagara International Airport (BUF)plane plane HYA - BUF
    9h 19m
    $150–986

Cape Cod to Buffalo by bus

Calendar12Weekly Buses
Duration14h 9mAverage Duration
Ticket$101Cheapest Price
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Questions & Answers

What companies run services between Cape Cod, MA, USA and Buffalo, NY, USA?

You can take a bus from Town Hall Lawton Bus Shelter to Buffalo via Hyannis Transportation Center, Boston, Bus Terminal South Station, Boston, and Syracuse Bus Station in around 14h 9m. Alternatively, American Airlines, JetBlue Airways, and Cape Air fly from Barnstable Municipal Airport (HYA) to Buffalo Niagara International Airport (BUF) 5 times a day.

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