There are 5 ways to get from Cancún to Key Largo by plane, shuttle, bus (Greyhound), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Miami International Airport, shuttle
best- Fly from Cancún International Airport (CUN) to Miami International Airport (MIA)plane CUN - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
6h 9m$302–547Fly to Key West International Airport, bus
cheapest- Fly from Cancún International Airport (CUN) to Key West International Airport (EYW)plane CUN - EYW
- Take the bus from Key West Airport to Key Largo Bus Stopbus
10h 21m$70–324Bus
- Take the bus from Terminal de Autobuses ADO Cancún to Villahermosabus
- Take the bus from Villahermosa to Reynosabus
- Take the bus from Reynosa to Houston Lockwoodbus
- Take the bus from Houston - Harrisburg Blvd to Miamibus
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
3d 5h$483–720Drive 2,940.8 mi
- Drive from Cancún to Key Largocar 2,940.8 mi
2d 7h$648–936Fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Cancún International Airport (CUN) to Fort Lauderdale–Hollywood International Airport (FLL)plane CUN - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
6h 37m$192–557
Cancún International Airport (CUN) to Miami International Airport (MIA) flights
Comparing Your Travel Options
The cheapest way to get from Cancún to Key Largo is to fly and bus which costs $70 - $330 and takes 10h 21m.
The fastest way to get from Cancún to Key Largo is to fly and shuttle which takes 6h 9m and costs $300 - $550.
No, there is no direct bus from Cancún to Key Largo. However, there are services departing from Terminal de Autobuses ADO Cancún and arriving at Key Largo Bus Stop via Villahermosa, Reynosa, Houston - Harrisburg Blvd and Miami Airport Station. The journey, including transfers, takes approximately 3 days 5h.
The distance between Cancún and Key Largo is 597 miles. The road distance is 2958 miles.
The best way to get from Cancún to Key Largo without a car is to bus which takes 3 days 5h and costs $480 - $750.
It takes approximately 6h 9m to get from Cancún to Key Largo, including transfers.
Cancún to Key Largo bus services, operated by ADO, depart from Terminal de Autobuses ADO Cancún station.
Cancún to Key Largo bus services, operated by ADO, arrive at Villahermosa station.
Yes, the driving distance between Cancún to Key Largo is 2958 miles. It takes approximately 2 days 7h to drive from Cancún to Key Largo.
There are 12+ hotels available in Key Largo.
What companies run services between Cancún, Mexico and Key Largo, FL, USA?
You can take a bus from Terminal de Autobuses ADO Cancún to Key Largo Bus Stop via Villahermosa, Reynosa, Houston Lockwood, Houston - Harrisburg Blvd, Miami, and Miami Airport Station in around 3d 5h.
- Website
- aa.com
Flights from Cancún International Airport to Miami International Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- $55–340
Flights from Cancún International Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 4h 55m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $50–290
- Website
- aeromexico.com
Flights from Cancún International Airport to Miami International Airport
- Ave. Duration
- 2h 2m
- When
- Tuesday and Wednesday
- Estimated price
- $55–340
Flights from Cancún International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 7h 48m
- When
- Every day
- Estimated price
- $90–410
- Website
- delta.com
Flights from Cancún International Airport to Miami International Airport
- Ave. Duration
- 2h 2m
- When
- Tuesday and Wednesday
- Estimated price
- $55–340
Flights from Cancún International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 7h 48m
- When
- Every day
- Estimated price
- $90–410
- Website
- jetblue.com
Flights from Cancún International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $70–400
- Website
- latam.com
Flights from Cancún International Airport to Miami International Airport
- Ave. Duration
- 1h 55m
- When
- Sunday
- Estimated price
- $110–440
- Website
- united.com
Flights from Cancún International Airport to Key West International Airport via Houston
- Ave. Duration
- 7h 3m
- When
- Saturday
- Estimated price
- $100–440
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $100–130
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $120–150
- Website
- Keys Shuttle
- Phone
- +52 55 4386 4652
- solucioneshola@ado.com.mx
- Website
- ado.com.mx
Bus from Terminal de Autobuses ADO Cancún to Villahermosa
- Ave. Duration
- 14h 25m
- Frequency
- Every 30 minutes
- Estimated price
- $85–140
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
Bus from Villahermosa to Reynosa
- Ave. Duration
- 22h 50m
- Frequency
- Twice daily
- Estimated price
- $140–210
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
- Phone
- +52 55 4386 4652
- solucioneshola@ado.com.mx
- Website
- ado.com.mx
Bus from Terminal de Autobuses ADO Cancún to Villahermosa
- Ave. Duration
- 14h 40m
- Frequency
- Every 4 hours
- Estimated price
- $85–160
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
- Phone
- +52 55 4386 4652
- solucioneshola@ado.com.mx
- Website
- ado.com.mx
Bus from Terminal de Autobuses ADO Cancún to Villahermosa
- Ave. Duration
- 14h 55m
- Frequency
- 3 times a day
- Estimated price
- $55–85
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
- Phone
- +52 81 2152 6736
- info@conexionestornado.com
- Website
- Tornado Bus Company
Bus from Reynosa to Houston Lockwood
- Ave. Duration
- 10h 15m
- Frequency
- Twice daily
- Estimated price
- $75
- Website
- Tornado Bus Company
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- Omnibus Express
Bus from Houston - Harrisburg Blvd to Miami
- Ave. Duration
- 24h 14m
- Frequency
- Once daily
- Estimated price
- $180–240
- Schedules at
- Omnibus Express
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $10–16
- Website
- Greyhound
Bus from Key West Airport to Key Largo Bus Stop
- Ave. Duration
- 2h 50m
- Frequency
- 3 times a day
- Estimated price
- $18–27
- Website
- Greyhound
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