From Canary Wharf Underground Station Tube to Baker Street Underground Station, Tube to London Paddington, then train to Slough. 56min £13. From Canary Wharf line 135 bus to Liverpool Street Underground Station, Tube to Ealing Broadway, then train to Slough. 1hrs 49min £11. From Poplar, Canada Square South bus to Victoria then line 702 bus to Slough Bus Station. 2hrs 18min £9. From Canary Wharf bus to Charing Cross, Trafalgar Square, bus to Hounslow Bus Station, then line 81 bus to Slough Bus Station. 2hrs 31min £6. From Canary Wharf taxi to Slough. 42min £114. From Canary Wharf drive to Slough. 42min £6.