Curico Viaggi operates a train from Camerino to Florence 6 times a week. Tickets cost $5 and the journey takes 55 min. Trenitalia also services this route every 4 hours. Alternatively, Contram Mobilita s.c.p.a. operates a bus from Camerino to Florence hourly, and the journey takes 20 min. FlixBus also services this route 3 times a week.
From Camerino, Terminal bus to Foligno then train to Firenze S.Maria Novella. 4 h 40 min 25€. From Camerino Terminal bus to Muccia then bus to Florence. 5 h 3 min 20€. From Camerino drive to Florence. 2 h 37 min 34€.