Travel within United States is: Fully open. See details.

There are 6 ways to get from Cambridge to Indianapolis by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  4h 43m

  1. Fly from Boston (BOS) to Indianapolis (IND) BOS - IND

$56 - $318

5 alternative options

Train, bus  •  16h 51m

  1. Take the train from Boston to New York Moynihan Train Hall Acela / ...
  2. Take the bus from New York, NY to Indianapolis, IN NYC - Indianapolis

$124 - $211

Bus via Lafayette Rd & 37th St  •  16h 59m

  1. Take the bus from Boston, MA Oak & Harrison to New York, NY
  2. Take the bus from New York, NY to Indianapolis, IN NYC - Indianapolis

$91 - $102

Bus  •  24h 42m

  1. Take the bus from South Station, Boston, MA to Port Authority Bus Terminal, New York, NY Peter Pan / ...
  2. Take the bus from New York to Indianapolis "Greyhound"

$105 - $163

Train  •  27h 6m

  1. Take the train from Boston to New York Moynihan Train Hall Acela / ...
  2. Take the train from New York Moynihan Train Hall to Indianapolis Cardinal

$134 - $266

Drive  •  15h 38m

  1. Drive from Cambridge to Indianapolis 938.3 miles

$90 - $140

Cambridge to Indianapolis by train, walk, subway and bus

The journey time between Cambridge and Indianapolis is around 16h 9m and covers a distance of around 955 miles. The fastest journey normally takes 16h 9m. Operated by Amtrak, Amtrak Northeast Regional, MTA and others, the Cambridge to Indianapolis service departs from Boston and arrives in Ohio St & Capitol Ave. Typically two services run weekly, although weekend and holiday schedules can vary so check in advance.

Route overview

Average journey time:
16h 9m
Fastest journey time:
16h 9m
Services per week:
2
Cheapest price:
$124
Carbon emissions:
163 kg CO2

First and last service

First service departs at:
16:20
Last service departs at:
16:20

The schedules shown below are for the next available departures.

Cambridge to Indianapolis train, walk, subway and bus schedules

Cambridge → Indianapolis
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Travel safe during COVID-19

Rules to follow in United States

2m

Recommended

Travel within United States

Domestic border crossings may be subject to approval, testing and quarantine
Nationwide control measures in place

COVID-19 help in United States

If you need help, visit the national COVID-19 website or call the COVID-19 Helpline 800-232-4636

Frequently Asked Questions


Yes, travel within United States is currently allowed.

Explore travel options

Domestic travel is not restricted, but some conditions may apply

  • Face masks are recommended
  • There is a social distancing requirement of 2 metres
  • Domestic border crossings may be subject to approval, testing and quarantine
  • Nationwide control measures in place

Explore travel options

The national COVID-19 helpline number in Indianapolis is 800-232-4636.

Wearing a face mask on public transport in Indianapolis is recommended.

The social distance requirement in Indianapolis is 2 metres.

Make yourself known to an official member of staff and/or call the national coronavirus helpline number on 800-232-4636.

Last updated: 16 Jun 2021
Exceptions may apply, for full details: Centers for Disease control and prevention (CDC).

We're working around the clock to bring you the latest COVID-19 travel updates.
This information is compiled from official sources. To the best of our knowledge, it is correct as of the last update.
Visit Rome2rio travel advice for general help.

Questions & Answers

The cheapest way to get from Cambridge to Indianapolis is to bus via Lafayette Rd & 37th St which costs $90 - $110 and takes 16h 59m.

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The quickest way to get from Cambridge to Indianapolis is to fly which costs $55 - $320 and takes 4h 43m.

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No, there is no direct bus from Cambridge to Indianapolis. However, there are services departing from Boston, MA Oak & Harrison and arriving at Ohio St & Illinois St via New York, NY and Lafayette Rd & 37th St. The journey, including transfers, takes approximately 16h 59m.

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No, there is no direct train from Cambridge to Indianapolis. However, there are services departing from Boston and arriving at Indianapolis via New York Moynihan Train Hall. The journey, including transfers, takes approximately 27h 6m.

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The distance between Cambridge and Indianapolis is 808 miles. The road distance is 938.3 miles.

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The best way to get from Cambridge to Indianapolis without a car is to train and bus which takes 16h 51m and costs $120 - $220.

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It takes approximately 4h 43m to get from Cambridge to Indianapolis, including transfers.

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Cambridge to Indianapolis bus services, operated by Coach Run, depart from Boston, MA Oak & Harrison station.

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Cambridge to Indianapolis train services, operated by Amtrak, depart from Boston station.

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The best way to get from Cambridge to Indianapolis is to fly which takes 4h 43m and costs $55 - $320. Alternatively, you can bus via Lafayette Rd & 37th St, which costs $90 - $110 and takes 16h 59m, you could also train, which costs $130 - $270 and takes 27h 6m.

Mode details

Map of how to get from Cambridge to Indianapolis.
Launch map view
  • Distance: 808 miles
  • Duration: 4h 43m

What companies run services between Cambridge, MA, USA and Indianapolis, IN, USA?

Allegiant Air, American Airlines and three other airlines fly from Cambridge to Indianapolis hourly. Alternatively, you can take a bus from Cambridge to Indianapolis via New York, NY, Indianapolis, IN, and Lafayette Rd & 37th St in around 16h 59m.

Airlines
Delta
Website
delta.com
Flights from Boston to Indianapolis
Ave. Duration
2h 55m
When
Every day
Estimated price
$60 - $440
Flights from Boston to Indianapolis via Detroit
Ave. Duration
4h 32m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$65 - $450
American Airlines
Website
aa.com
Flights from Boston to Indianapolis
Ave. Duration
2h 50m
When
Every day
Estimated price
$140 - $500
Flights from Boston to Indianapolis via Philadelphia
Ave. Duration
4h 25m
When
Every day
Estimated price
$140 - $500
Flights from Boston to Indianapolis via Reagan Washington
Ave. Duration
4h 32m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$140 - $500
Southwest Airlines
Website
southwest.com
Flights from Boston to Indianapolis via Baltimore
Ave. Duration
4h 10m
When
Every day
Estimated price
$120 - $440
United Airlines
Website
united.com
Flights from Boston to Indianapolis via Washington Dulles
Ave. Duration
4h 22m
When
Every day
Estimated price
$180 - $950
Allegiant Air
Website
allegiantair.com
Flights from Boston to Indianapolis
Ave. Duration
2h 20m
When
Monday and Friday
Estimated price
$95 - $410
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Boston to New York Moynihan Train Hall
Ave. Duration
3h 36m
Frequency
Every 3 hours
Estimated price
$35 - $55
Schedules at
amtrak.com
Coach Seat
$35 - $55
Premium
$210 - $290
Flexi Coach Seat
$65 - $100
Business Seat
$65 - $95
Train from New York Moynihan Train Hall to Indianapolis
Ave. Duration
22h 30m
Frequency
6 times a week
Estimated price
$95 - $140
Schedules at
amtrak.com
Coach Seat
$95 - $140
Premium
$320 - $440
Flexi Coach Seat
$190 - $290
Business Seat
$200 - $290
Amtrak Northeast Regional

Amtrak’s Northeast Regional train service serves the US’ busy northeast corridor from Virginia to Massachusetts; major stops include Boston, Providence, New York City, Philadelphia, Washington DC and Baltimore. Amenities include Wi-Fi, a quiet car, cafe and business-class seating, and travelling with a small dog or cat is permitted. Book at least 14 days in advance for a cheaper Saver Fare.

Rome2rio's guide to Amtrak Northeast Regional
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Boston to New York Moynihan Train Hall
Ave. Duration
4h 58m
Frequency
Every 3 hours
Estimated price
$60 - $130
Schedules at
amtrak.com
Reserved Coach Seat
$60 - $130
Business Class Seat
$100 - $180
Bus operators
Indiana Travel Express
Bus from New York, NY to Indianapolis, IN
Ave. Duration
11h
Frequency
3 times a week
Estimated price
$80
Schedules at
gotobus.com
Book at
gotobus.com
Coach Run
Website
coachrun.com
Bus from Boston, MA Oak & Harrison to New York, NY
Ave. Duration
4h 10m
Frequency
3 times a day
Estimated price
$9 - $20
Schedules at
coachrun.com
Book at
gotobus.com
Peter Pan Bus Lines
Phone
1-800-343-9999
Website
peterpanbus.com
Bus from South Station, Boston, MA to Port Authority Bus Terminal, New York, NY
Ave. Duration
4h 20m
Frequency
Every 3 hours
Estimated price
$35 - $50
Website
peterpanbus.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Boston to New York
Ave. Duration
4h 30m
Frequency
4 times a day
Estimated price
$27 - $40
Website
greyhound.com
Economy
$27 - $40
Flexible
$50 - $70
Bus from New York to Indianapolis
Ave. Duration
18h 15m
Frequency
Twice daily
Estimated price
$75 - $110
Website
greyhound.com
Economy
$75 - $110
Flexible
$110 - $170

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The quickest flight from Boston Airport to Indianapolis Airport is the direct flight which takes 2h 20m.

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Cambridge to Indianapolis bus services, operated by Indiana Travel Express, arrive at Indianapolis, IN station.

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Cambridge to Indianapolis train services, operated by Amtrak, arrive at Indianapolis station.

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Yes, the driving distance between Cambridge to Indianapolis is 938 miles. It takes approximately 15h 38m to drive from Cambridge to Indianapolis.

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Allegiant Air, Southwest Airlines, United Airlines and two other airlines offer flights from Boston Airport to Indianapolis Airport.

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Book your Cambridge to Indianapolis train tickets online with Omio.

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There are 224+ hotels available in Indianapolis. Prices start at $100 USD per night.

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