Rome2Rio

How to get fromCalexico to St. Louisby bus, plane, bus (Flixbus, Greyhound), train or car

Find Transport to St. Louis

See all options

There are 8 ways to get from Calexico to St. Louis by bus, plane, bus (Flixbus, Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to San Diego International Airport, fly

    best
    1. Take the bus from Calexico Bus Station to San Diego Greyhound Bus Stopbus
    2. Fly from San Diego International Airport (SAN) to Lambert–St. Louis International Airport (STL)planeSAN - STL
    8h 34m
    $236–987
  2. Bus

    cheapest
    1. Take the bus from Calexico Bus Station to Indio Bus StationbusFlixBus 2055 / ...
    2. Take the bus from Indio Bus Station to St Louis Bus StationbusGreyhound US1210
    39h 30m
    $151–343
  3. Bus, train

    1. Take the bus from Calexico Bus Station to Yuma County Area TransitbusFlixBus 2055 / ...
    2. Take the train from Yuma Amtrak to St. LouistrainTexas Eagle
    2d 4h
    $194–655
  4. Drive 1,680.8 mi

    1. Drive from Calexico to St. Louiscar1,680.8 mi
    27h 26m
    $307–444
  5. Bus to Phoenix, fly

    1. Take the bus from Calexico Bus Station to Phoenix Bus Stationbus
    2. Fly from Phoenix (PHX) to Lambert–St. Louis International Airport (STL)planePHX - STL
    9h
    $361–629
  6. Fly from Imperial County Airport

    1. Fly from Imperial County Airport (IPL) to Lambert–St. Louis International Airport (STL)planeIPL - STL
    6h 38m
    $162–649
  7. Bus to Yuma International Airport, fly

    1. Take the bus from Calexico Bus Station to Yuma County Area Transitbus
    2. Fly from Yuma International Airport (YUM) to Lambert–St. Louis International Airport (STL)planeYUM - STL
    10h 3m
    $188–860
  8. Bus to Los Angeles International Airport, fly

    1. Take the bus from Calexico Bus Station to Los Angeles Downtownbus
    2. Fly from Los Angeles International Airport (LAX) to Lambert–St. Louis International Airport (STL)planeLAX - STL
    10h 23m
    $281–744

Calexico to St. Louis by bus

Calendar12Weekly Buses
Duration39h 30mAverage Duration
Ticket$151Cheapest Price
See schedules

Questions & Answers

What companies run services between Calexico, CA, USA and St. Louis, MO, USA?

You can take a bus from Calexico Bus Station to St Louis Bus Station via Indio Bus Station in around 39h 30m. Alternatively, Southern Airways Express, Southwest Airlines, and American Airlines fly from Imperial County Airport (IPL) to Lambert–St. Louis International Airport (STL) twice daily.

Transport is disrupted due to the Russia-Ukraine war. Read more

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers