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How to get fromCalexico to Chicagoby bus, plane, bus (Flixbus, Greyhound), train or car

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There are 9 ways to get from Calexico to Chicago by bus, plane, bus (Flixbus, Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to San Diego International Airport, fly to Chicago Midway International Airport

    best
    1. Take the bus from Calexico Bus Station to San Diego Greyhound Bus Stopbus bus
    2. Fly from San Diego International Airport (SAN) to Chicago Midway International Airport (MDW)plane plane SAN - MDW
    8h 57m
    $214–940

  2. Bus to Yuma International Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Take the bus from Calexico Bus Station to Yuma County Area Transitbus bus
    2. Fly from Yuma International Airport (YUM) to Chicago O'Hare International Airport (ORD)plane plane YUM - ORD
    10h 35m
    $109–482

  3. Bus

    1. Take the bus from Calexico Bus Station to Phoenix Bus Stationbus bus
    2. Take the bus from Phoenix Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus
    43h
    $175–333

  4. Bus, train via San Bernardino

    1. Take the bus from Calexico Bus Station to San Bernardinobus bus FlixBus 2055
    2. Take the train from San Bernardino to Chicago Union Stationtrain train Southwest Chief
    46h 54m
    $244–641

  5. Drive 1,924 mi

    1. Drive from Calexico to Chicagocar car 1,924 mi
    34h 19m
    $352–508

  6. Bus to San Diego International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Calexico Bus Station to San Diego Greyhound Bus Stopbus bus
    2. Fly from San Diego International Airport (SAN) to Chicago O'Hare International Airport (ORD)plane plane SAN - ORD
    9h 17m
    $154–640

  7. Bus to Phoenix, fly to Chicago Midway International Airport

    1. Take the bus from Calexico Bus Station to Phoenix Bus Stationbus bus
    2. Fly from Phoenix (PHX) to Chicago Midway International Airport (MDW)plane plane PHX - MDW
    9h 24m
    $162–728

  8. Fly Imperial County Airport to Chicago Midway International Airport

    1. Fly from Imperial County Airport (IPL) to Chicago Midway International Airport (MDW)plane plane IPL - MDW
    8h 12m
    $161–601

  9. Bus, train

    1. Take the bus from Calexico Bus Station to Yuma County Area Transitbus bus FlixBus 2055 / ...
    2. Take the train from Yuma Amtrak to Chicago Union Stationtrain train Texas Eagle
    2d 11h
    $216–705

Calexico to Chicago by bus

Calendar11Weekly Buses
Duration43hAverage Duration
Ticket$175Cheapest Price
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Questions & Answers

What companies run services between Calexico, CA, USA and Chicago, IL, USA?

You can take a bus from Calexico Bus Station to Chicago Bus Station via Phoenix Bus Station and St Louis Bus Station in around 43h. Alternatively, Southern Airways Express and Southwest Airlines fly from Imperial County Airport (IPL) to Chicago Midway International Airport (MDW) once daily.

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Need to know: Greyhound

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