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How to get fromBuffalo to Wiseby plane, car, bus or train

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There are 7 ways to get from Buffalo to Wise by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport, drive

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Tri-Cities Regional Tn/Va Airport (TRI)plane plane BUF - TRI
    2. Drive from Tri-Cities-Regional-Airport-TRI to Wisecar car
    7h 37m
    $183–1,045

  2. Drive 565.7 mi

    cheapest
    1. Drive from Buffalo to Wisecar car 565.7 mi
    11h 8m
    $104–150

  3. Bus, drive via New York

    1. Take the bus from Buffalo to Port Authority Bus Terminalbus bus
    2. Take the bus from New York City to Johnson Citybus bus Ny
    3. Drive from Johnson City to Wisecar car
    21h 43m
    $135–217

  4. Bus to Rochester, fly, drive

    1. Take the bus from Buffalo, NY to Rochester, NYbus bus
    2. Fly from Rochester (ROC) to Tri-Cities Regional Tn/Va Airport (TRI)plane plane ROC - TRI
    3. Drive from Tri-Cities-Regional-Airport-TRI to Wisecar car
    9h 27m
    $173–900

  5. Train, bus, drive

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the bus from New York City to Johnson Citybus bus Ny
    3. Drive from Johnson City to Wisecar car
    22h
    $147–269

  6. Bus, drive

    1. Take the bus from Buffalo to New York Midtownbus bus
    2. Take the bus from New York City to Johnson Citybus bus Ny
    3. Drive from Johnson City to Wisecar car
    22h 5m
    $135–222

  7. Train, bus, drive via New York

    1. Take the train from Buffalo to New York Penn Stationtrain train
    2. Take the bus from New York City to Johnson Citybus bus Ny
    3. Drive from Johnson City to Wisecar car
    23h 32m
    $144–232

Buffalo Niagara International Airport (BUF) to Tri-Cities Regional Tn/Va Airport (TRI) flights

Calendar47Weekly Planes
Duration6h 56mAverage Duration
Ticket$172Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Wise, VA, USA?

There is no direct connection from Buffalo to Wise. However, you can take the bus to Buffalo Niagara International Airport, walk to Buffalo Niagara International Airport (BUF) airport, fly to Tri-Cities Regional Tn/Va Airport (TRI), then drive to Wise. Alternatively, you can take a bus from Buffalo to Wise via Port Authority Bus Terminal, 34 St-Herald Sq, East Broadway, New York City, and Johnson City in around 21h 43m.

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