There are 9 ways to get from Buffalo to Saco by plane, train, bus (Flixbus, Greyhound, Amtrak), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Buffalo Niagara International Airport to Boston Logan Airport, train
best- Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)BUF - BOS
- Take the train from Woburn Amtrak Station to Saco Amtrak Station
6h 36m$102–631Bus, train
cheapest- Take the bus from Buffalo to Ithaca
- Take the bus from Ithaca, NY to Boston, MA
- Take the train from Boston to Saco Amtrak Station
15h 55m$80–193Bus
- Take the bus from Buffalo to Syracuse Bus Station
- Take the bus from Syracuse Bus Station to Boston
- Take the bus from Boston, MA - South Station to Portland, ME
15h 18m$91–276Train (Amtrak)
- Take the train from Buffalo Depew Station to BostonLake Shore Limited
- Take the train from Boston to Saco Amtrak StationDowneaster
15h 53m$88–276Drive 493.9 mi
- Drive from Buffalo to Saco493.9 mi
10h 2m$91–131Fly Buffalo Niagara International Airport to Portland
- Fly from Buffalo Niagara International Airport (BUF) to Portland (PWM)BUF - PWM
8h 3m$131–768Fly Buffalo Niagara International Airport to Augusta State Airport, bus
- Fly from Buffalo Niagara International Airport (BUF) to Augusta State Airport (AUG)BUF - AUG
- Take the bus from Augusta Transportation Center to Portland Transportation Center
9h 1m$116–555Bus to Rochester, fly to Boston Logan Airport, train
- Take the bus from Buffalo, NY to Rochester, NY
- Fly from Rochester (ROC) to Boston Logan Airport (BOS)ROC - BOS
- Take the train from Woburn Amtrak Station to Saco Amtrak Station
8h 25m$204–654Bus to Toronto Island Airport, fly to Boston Logan Airport, train
- Take the bus from Buffalo to Toronto
- Fly from Toronto Island Airport (YTZ) to Boston Logan Airport (BOS)YTZ - BOS
- Take the train from Woburn Amtrak Station to Saco Amtrak Station
10h 34m$161–751
Buffalo to Saco by bus
Questions & Answers
The cheapest way to get from Buffalo to Saco is to bus and train which costs $80 - $200 and takes 15h 55m.
The fastest way to get from Buffalo to Saco is to fly and train which takes 6h 36m and costs $100 - $650.
No, there is no direct bus from Buffalo to Saco. However, there are services departing from Buffalo and arriving at 292 Main St via Syracuse Bus Station, Boston, MA - South Station, Ptc O/B and St John St. The journey, including transfers, takes approximately 15h 18m.
No, there is no direct train from Buffalo to Saco station. However, there are services departing from Buffalo and arriving at Saco Amtrak Station via Buffalo Depew Station, Back Bay and Boston. The journey, including transfers, takes approximately 15h 53m.
The distance between Buffalo and Saco is 512 miles. The road distance is 496.8 miles.
The best way to get from Buffalo to Saco without a car is to bus which takes 15h 18m and costs $90 - $280.
It takes approximately 6h 36m to get from Buffalo to Saco, including transfers.
Buffalo to Saco bus services, operated by Flixbus USA, depart from Buffalo station.
Buffalo to Saco train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from Buffalo to Saco is to bus which takes 15h 18m and costs $90 - $280. Alternatively, you can train, which costs $85 - $280 and takes 15h 53m, you could also fly, which costs $130 - $800 and takes 8h 3m.
What companies run services between Buffalo, NY, USA and Saco, ME, USA?
You can take a bus from Buffalo to 292 Main St via Syracuse Bus Station, Boston, Boston, MA - South Station, Ptc O/B, Congress + Union Square Plaza, and St John St in around 15h 18m. Alternatively, you can take a train from Buffalo to Saco Amtrak Station via Buffalo Depew Station, Boston, Back Bay, North Station, and Boston in around 15h 53m.
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $80–550
Flights from Buffalo Niagara International Airport to Portland via New York JFK
- Ave. Duration
- 6h 23m
- When
- Wednesday to Sunday
- Estimated price
- $120–800
Flights from Buffalo Niagara International Airport to Augusta State Airport via Boston Logan Airport
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $80–480
Flights from Buffalo Niagara International Airport to Augusta State Airport via New York JFK, Boston Logan Airport
- Ave. Duration
- 7h
- When
- Every day
- Estimated price
- $85–500
Flights from Buffalo Niagara International Airport to Augusta State Airport via Baltimore, Boston Logan Airport
- Ave. Duration
- 6h 10m
- When
- Monday to Wednesday
- Estimated price
- $95–550
Flights from Buffalo Niagara International Airport to Augusta State Airport via Reagan Washington, Boston Logan Airport
- Ave. Duration
- 6h 15m
- When
- Every day
- Estimated price
- $100–550
Flights from Rochester to Boston Logan Airport via New York JFK
- Ave. Duration
- 3h 46m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $75–470
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $80–550
Flights from Buffalo Niagara International Airport to Portland via Reagan Washington
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $150–850
Flights from Buffalo Niagara International Airport to Portland via New York La Guardia
- Ave. Duration
- 5h 38m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–750
Flights from Buffalo Niagara International Airport to Portland via Philadelphia
- Ave. Duration
- 7h 4m
- When
- Every day
- Estimated price
- $130–800
Flights from Rochester to Boston Logan Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $65–440
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Portland via New York La Guardia
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $120–750
Flights from Buffalo Niagara International Airport to Portland via Detroit
- Ave. Duration
- 6h 24m
- When
- Every day
- Estimated price
- $160–900
Flights from Buffalo Niagara International Airport to Portland via New York JFK
- Ave. Duration
- 7h 29m
- When
- Every day
- Estimated price
- $120–800
Flights from Rochester to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 3h 44m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $70–460
- Website
- united.com
Flights from Buffalo Niagara International Airport to Portland via Newark
- Ave. Duration
- 5h 50m
- When
- Every day
- Estimated price
- $120–800
Flights from Buffalo Niagara International Airport to Portland via Washington Dulles
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $150–850
Flights from Toronto Island Airport to Boston Logan Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $50–320
Flights from Toronto Island Airport to Boston Logan Airport via Washington Dulles
- Ave. Duration
- 3h 53m
- When
- Monday and Saturday
- Estimated price
- $65–380
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Portland via Baltimore
- Ave. Duration
- 3h 53m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–850
Flights from Rochester to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 45m
- When
- Monday to Wednesday
- Estimated price
- $90–550
- Website
- flyporter.com
Flights from Toronto Island Airport to Boston Logan Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $110–470
- Website
- capeair.com
Flights from Buffalo Niagara International Airport to Augusta State Airport via Boston Logan Airport
- Ave. Duration
- 7h 35m
- When
- Every day
- Estimated price
- $80–480
Flights from Buffalo Niagara International Airport to Augusta State Airport via Baltimore, Boston Logan Airport
- Ave. Duration
- 6h 10m
- When
- Monday to Wednesday
- Estimated price
- $95–550
Flights from Buffalo Niagara International Airport to Augusta State Airport via Reagan Washington, Boston Logan Airport
- Ave. Duration
- 6h 15m
- When
- Every day
- Estimated price
- $100–550
- Website
- aircanada.com
Flights from Toronto Island Airport to Boston Logan Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $50–320
Flights from Toronto Island Airport to Boston Logan Airport via Montreal
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $55–340
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Woburn Amtrak Station to Saco Amtrak Station
- Ave. Duration
- 1h 47m
- Frequency
- Every 4 hours
- Estimated price
- $11–70
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $18–30
- Coach Seat short notice purchase
- $11–70
- Business - advance purchase
- $15–100
- Business Class
- $26–180
Train from Buffalo Depew Station to Boston
- Ave. Duration
- 11h 19m
- Frequency
- Once daily
- Estimated price
- $50–170
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $50–120
- Coach Seat short notice purchase
- $60–170
- Business - advance purchase
- $85–360
- Business Class
- $140–390
Train from Boston to Saco Amtrak Station
- Ave. Duration
- 2h 5m
- Frequency
- Every 4 hours
- Estimated price
- $26–30
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Every 4 hours
- Estimated price
- $26–40
- Schedules at
- flixbus.com
Bus from Syracuse Bus Station to Boston
- Ave. Duration
- 6h 20m
- Frequency
- Once daily
- Estimated price
- $45–130
- Schedules at
- flixbus.com
Bus from Buffalo to Toronto
- Ave. Duration
- 3h 25m
- Frequency
- Twice daily
- Estimated price
- $19–35
- Schedules at
- flixbus.com
Bus from Buffalo to Ithaca
- Ave. Duration
- 3h 45m
- Frequency
- 6 times a week
- Estimated price
- $30–65
- Schedules at
- flixbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- 4 times a day
- Estimated price
- $28–100
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $28–95
- Flexible
- $55–100
Bus from Buffalo to Toronto
- Ave. Duration
- 2h 50m
- Frequency
- Twice daily
- Estimated price
- $21–60
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $21–60
- Flexible
- $40–60
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- 4 times a day
- Estimated price
- $26–45
- Website
- https://www.greyhound.com/
Bus from Syracuse Bus Station to Boston
- Ave. Duration
- 7h 40m
- Frequency
- Once daily
- Estimated price
- $40–130
- Website
- https://www.greyhound.com/
Bus from Buffalo to Toronto
- Ave. Duration
- 2h 45m
- Frequency
- 3 times a day
- Estimated price
- $17–30
- Website
- https://www.greyhound.com/
- Phone
- +1 800 639 3317
- info@concordcoachlines.com
- Website
- concordcoachlines.com
Bus from Boston, MA - South Station to Portland, ME
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $22–30
- Website
- https://concordcoachlines.com
Bus from Augusta Transportation Center to Portland Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- Every 2 hours
- Estimated price
- $13–17
- Website
- https://concordcoachlines.com
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Boston, MA - South Station to Portland, ME
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $21–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $21–45
Bus from Augusta Transportation Center to Portland Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- 5 times a day
- Estimated price
- $13–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $13–45
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Buffalo, NY to Rochester, NY
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $20–55
- Website
- https://www.ourbus.com
Bus from Ithaca, NY to Boston, MA
- Ave. Duration
- 7h 45m
- Frequency
- Once a week
- Estimated price
- $20–95
- Website
- https://www.ourbus.com
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More Questions & Answers
Buffalo to Saco bus services, operated by Flixbus USA, arrive at Syracuse Bus Station.
Buffalo to Saco train services, operated by Amtrak, arrive at Boston station.
Yes, the driving distance between Buffalo to Saco is 497 miles. It takes approximately 10h 2m to drive from Buffalo to Saco.
Book your Buffalo to Saco train tickets online with Omio.
There are 335+ hotels available in Saco.
















