There are 7 ways to get from Buffalo to Saco by plane, train, bus (Greyhound, Amtrak), train (Amtrak), car, bus, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Buffalo Niagara International Airport to Boston Logan Airport, train
best- Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane BUF - BOS
- Take the train from Woburn Amtrak Station to Saco Amtrak Stationtrain
6h 12m$128–692Bus via Ithaca (Flixbus)
cheapest- Take the bus from Buffalo to Ithacabus
- Take the bus from Ithaca to Springfield Union Stationbus
- Take the bus from Springfield Union Station to City of Portlandbus
18h 11m$83–147Bus
- Take the bus from Buffalo to Bostonbus Greyhound US0171
- Take the bus from Boston, MA - South Station to Portland, MEbus Logan Airport / ...
14h 48m$102–197Train (Amtrak)
- Take the train from Buffalo Depew Station to Bostontrain Lake Shore Limited
- Take the train from Boston to Saco Amtrak Stationtrain Downeaster
15h 52m$169–428Drive 493.9 mi
- Drive from Buffalo to Sacocar 493.9 mi
10h 6m$91–131Fly Buffalo Niagara International Airport to Portland
- Fly from Buffalo Niagara International Airport (BUF) to Portland (PWM)plane BUF - PWM
7h 27m$154–845Bus to Rochester, fly to Boston Logan Airport, train
- Take the bus from Buffalo to Rochester Bus Stopbus
- Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane ROC - BOS
- Take the train from Woburn Amtrak Station to Saco Amtrak Stationtrain
7h 46m$290–860
Buffalo to Saco by bus
Questions & Answers
The cheapest way to get from Buffalo to Saco is to bus via Ithaca which costs $80 - $150 and takes 18h 11m.
The fastest way to get from Buffalo to Saco is to fly and train which takes 6h 12m and costs $120 - $700.
No, there is no direct bus from Buffalo to Saco. However, there are services departing from Buffalo and arriving at 292 Main St via Boston, MA - South Station, Portland Transportation Center and St John St. The journey, including transfers, takes approximately 14h 48m.
No, there is no direct train from Buffalo to Saco station. However, there are services departing from Buffalo and arriving at Saco Amtrak Station via Buffalo Depew Station, Back Bay and Boston. The journey, including transfers, takes approximately 15h 52m.
The distance between Buffalo and Saco is 509 miles. The road distance is 496.8 miles.
The best way to get from Buffalo to Saco without a car is to bus which takes 14h 48m and costs $100 - $200.
It takes approximately 6h 12m to get from Buffalo to Saco, including transfers.
Buffalo to Saco bus services, operated by Greyhound USA, depart from Buffalo station.
Buffalo to Saco train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from Buffalo to Saco is to bus which takes 14h 48m and costs $100 - $200. Alternatively, you can train, which costs $160 - $430 and takes 15h 52m, you could also fly, which costs $150 - $850 and takes 7h 27m.
What companies run services between Buffalo, NY, USA and Saco, ME, USA?
You can take a bus from Buffalo to 292 Main St via Boston, Boston, MA - South Station, Portland Transportation Center, Congress + Union Square Plaza, and St John St in around 14h 48m. Alternatively, you can take a train from Buffalo to Saco Amtrak Station via Buffalo Depew Station, Boston, Back Bay, North Station, and Boston in around 15h 52m.
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $90–600
Flights from Buffalo Niagara International Airport to Portland via Reagan Washington
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $170–950
Flights from Buffalo Niagara International Airport to Portland via Philadelphia
- Ave. Duration
- 6h 24m
- When
- Every day
- Estimated price
- $150–850
Flights from Rochester to Boston Logan Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $65–450
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Portland via Detroit
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Buffalo Niagara International Airport to Portland via New York La Guardia
- Ave. Duration
- 5h 33m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–800
Flights from Buffalo Niagara International Airport to Portland via New York JFK
- Ave. Duration
- 5h 53m
- When
- Every day
- Estimated price
- $140–850
Flights from Rochester to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 3h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $75–480
- Website
- united.com
Flights from Buffalo Niagara International Airport to Portland via Washington Dulles
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $170–950
Flights from Buffalo Niagara International Airport to Portland via Newark
- Ave. Duration
- 6h 33m
- When
- Every day
- Estimated price
- $140–850
Flights from Rochester to Boston Logan Airport via Newark
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- $75–480
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Portland via Baltimore
- Ave. Duration
- 4h 54m
- When
- Every day
- Estimated price
- $160–900
Flights from Rochester to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 42m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–550
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $90–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Woburn Amtrak Station to Saco Amtrak Station
- Ave. Duration
- 1h 47m
- Frequency
- Every 4 hours
- Estimated price
- $23–55
- Website
- https://www.amtrak.com/home.html
Train from Buffalo Depew Station to Boston
- Ave. Duration
- 11h 19m
- Frequency
- Once daily
- Estimated price
- $130–290
- Website
- https://www.amtrak.com/home.html
Train from Boston to Saco Amtrak Station
- Ave. Duration
- 2h 5m
- Frequency
- Every 4 hours
- Estimated price
- $27–60
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Buffalo to Boston
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $75–150
- Website
- https://www.greyhound.com/
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $12–24
- Website
- https://www.greyhound.com/
- Phone
- +1 800 639 3317
- info@concordcoachlines.com
- Website
- concordcoachlines.com
Bus from Boston, MA - South Station to Portland, ME
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $22–30
- Website
- https://concordcoachlines.com
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Boston, MA - South Station to Portland, ME
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $21–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $21–45
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- Every 3 hours
- Estimated price
- $9–17
- Schedules at
- flixbus.com
Bus from Buffalo to Ithaca
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- $21–40
- Schedules at
- flixbus.com
Bus from Ithaca to Springfield Union Station
- Ave. Duration
- 6h 15m
- Frequency
- 5 times a week
- Estimated price
- $35–65
- Schedules at
- flixbus.com
Bus from Springfield Union Station to City of Portland
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $25–45
- Schedules at
- flixbus.com
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More Questions & Answers
Buffalo to Saco bus services, operated by Greyhound USA, arrive at Boston station.
Buffalo to Saco train services, operated by Amtrak, arrive at Boston station.
Yes, the driving distance between Buffalo to Saco is 497 miles. It takes approximately 10h 6m to drive from Buffalo to Saco.
Book your Buffalo to Saco train tickets online with Omio.
There are 1525+ hotels available in Saco.











