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How to get fromBuffalo to Portland, MEby plane, bus (Flixbus, Greyhound, Amtrak), train, bus, car or bus (Amtrak)

Find Transport to Portland, ME

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There are 7 ways to get from Buffalo to Portland, ME by plane, bus (Flixbus, Greyhound, Amtrak), train, bus, car, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Portland

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Portland (PWM)plane plane BUF - PWM
    5h 39m
    $124–780

  2. Bus via Buffalo, NY

    cheapest
    1. Take the bus from Buffalo, NY to Syracuse, NYbus bus
    2. Take the bus from Syracuse, NY to Boston, MAbus bus
    3. Take the bus from Boston, MA - South Station to Portland, MEbus bus
    13h 14m
    $72–175

  3. Bus

    1. Take the bus from Buffalo to Syracuse Bus Stationbus bus
    2. Take the bus from Syracuse Bus Station to Bostonbus bus
    3. Take the bus from Boston, MA - South Station to Portland, MEbus bus
    12h 24m
    $93–217

  4. Train, bus

    1. Take the train from Buffalo Depew Station to Bostontrain train Lake Shore Limited
    2. Take the bus from Boston, MA - South Station to Portland, MEbus bus Logan Airport / ...
    14h 58m
    $85–329

  5. Drive 508 mi

    1. Drive from Buffalo to Portland, MEcar car 508 mi
    10h 20m
    $93–134

  6. Fly to Boston Logan Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    2. Take the bus from Logan International Airport to Portland, MEbus bus
    5h 26m
    $126–760

  7. Fly to Augusta State Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Augusta State Airport (AUG)plane plane BUF - AUG
    2. Take the bus from Augusta Transportation Center to Portland Transportation Centerbus bus
    7h 41m
    $123–695

Buffalo to Portland, ME by bus

Calendar13Weekly Buses
Duration12h 24mAverage Duration
Ticket$93Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Portland, ME, USA?

Southwest Airlines, American Airlines, and three other airlines fly from Buffalo Niagara International Airport (BUF) to Portland (PWM) hourly. Alternatively, you can take a bus from Buffalo to Portland, ME via Syracuse Bus Station, Boston, and Boston, MA - South Station in around 12h 24m.

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