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How to get fromBuffalo to Portland, MEby plane, bus (Flixbus, Greyhound, Amtrak), train, bus or car

Find Transport to Portland, ME

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There are 8 ways to get from Buffalo to Portland, ME by plane, bus (Flixbus, Greyhound, Amtrak), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Portland

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Portland (PWM)plane plane BUF - PWM
    5h 29m
    $126–778

  2. Bus

    cheapest
    1. Take the bus from Buffalo to Syracuse Bus Stationbus bus
    2. Take the bus from Syracuse Bus Station to Bostonbus bus
    3. Take the bus from Boston, MA - South Station to Portland, MEbus bus
    13h 44m
    $75–193

  3. Train, bus

    1. Take the train from Buffalo Depew Station to Bostontrain train Lake Shore Limited
    2. Take the bus from Boston, MA - South Station to Portland, MEbus bus Logan Airport / ...
    14h 58m
    $140–389

  4. Drive 508 mi

    1. Drive from Buffalo to Portland, MEcar car 508 mi
    10h 20m
    $93–134

  5. Fly Buffalo Niagara International Airport to Boston Logan Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    2. Take the bus from Logan International Airport to Portland, MEbus bus
    5h 26m
    $128–708

  6. Fly Buffalo Niagara International Airport to Augusta State Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Augusta State Airport (AUG)plane plane BUF - AUG
    2. Take the bus from Augusta Transportation Center to Portland Transportation Centerbus bus
    7h 47m
    $120–643

  7. Bus to Rochester, fly to Boston Logan Airport, bus

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane plane ROC - BOS
    3. Take the bus from Logan International Airport to Portland, MEbus bus
    6h 40m
    $249–825

  8. Bus via New York

    1. Take the bus from Buffalo to New Yorkbus bus Adt N813 / ...
    2. Take the bus from New York, NY to Portland, MEbus bus New York
    15h 15m
    $129–375

Buffalo to Portland, ME by bus

Calendar12Weekly Buses
Duration13h 44mAverage Duration
Ticket$75Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Portland, ME, USA?

Southwest Airlines, JetBlue Airways, and three other airlines fly from Buffalo Niagara International Airport (BUF) to Portland (PWM) hourly. Alternatively, you can take a bus from Buffalo to Portland, ME via Syracuse Bus Station, Boston, and Boston, MA - South Station in around 13h 44m.

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