Rome2Rio

How to get fromBuffalo to Portland, MEBy plane, bus (Greyhound, Amtrak), train, bus, car, or bus (Flixbus, Amtrak)

Find Transport to Portland, ME

See all options

There are 8 ways to get from Buffalo to Portland, ME by plane, bus (Greyhound, Amtrak), train, bus, car, or bus (Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Portland

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Portland (PWM)plane plane BUF - PWM
    5h 23m
    $126–778

  2. Drive 508 mi

    cheapest
    1. Drive from Buffalo to Portland, MEcar car 508 mi
    10h 20m
    $93–134

  3. Bus

    1. Take the bus from Buffalo to Bostonbus bus Greyhound US0171
    2. Take the bus from Boston, MA - South Station to Portland, MEbus bus Logan Airport / ...
    12h 19m
    $97–189

  4. Train, bus

    1. Take the train from Buffalo Depew Station to Bostontrain train Lake Shore Limited
    2. Take the bus from Boston, MA - South Station to Portland, MEbus bus Logan Airport / ...
    14h 58m
    $160–419

  5. Fly Buffalo Niagara International Airport to Boston Logan Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    2. Take the bus from Logan International Airport to Portland, MEbus bus
    5h 18m
    $108–608

  6. Fly Buffalo Niagara International Airport to Augusta State Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Augusta State Airport (AUG)plane plane BUF - AUG
    2. Take the bus from Augusta Transportation Center to Portland Transportation Centerbus bus
    6h 46m
    $105–513

  7. Bus to Rochester, fly to Boston Logan Airport, bus

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane plane ROC - BOS
    3. Take the bus from Logan International Airport to Portland, MEbus bus
    6h 52m
    $280–876

  8. Bus via Ithaca

    1. Take the bus from Buffalo to Ithacabus bus
    2. Take the bus from Ithaca to Bostonbus bus
    3. Take the bus from Boston, MA - South Station to Portland, MEbus bus
    14h 54m
    $93–166

Buffalo to Portland, ME by bus

Calendar7Weekly Buses
Duration12h 19mAverage Duration
Ticket$97Cheapest Price
See schedules

Questions & Answers

What companies run services between Buffalo, NY, USA and Portland, ME, USA?

Southwest Airlines, JetBlue Airways, and three other airlines fly from Buffalo Niagara International Airport (BUF) to Portland (PWM) hourly. Alternatively, you can take a bus from Buffalo to Portland, ME via Boston and Boston, MA - South Station in around 12h 19m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Trips from Buffalo

Trips to Portland, ME

Popular routes