There are 8 ways to get from Buffalo to Portland, ME by plane, bus (Greyhound, Amtrak), train, bus, car, or bus (Flixbus, Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Buffalo Niagara International Airport to Portland
best- Fly from Buffalo Niagara International Airport (BUF) to Portland (PWM)plane BUF - PWM
5h 23m$126–778Drive 508 mi
cheapest- Drive from Buffalo to Portland, MEcar 508 mi
10h 20m$93–134Bus
- Take the bus from Buffalo to Bostonbus Greyhound US0171
- Take the bus from Boston, MA - South Station to Portland, MEbus Logan Airport / ...
12h 19m$97–189Train, bus
- Take the train from Buffalo Depew Station to Bostontrain Lake Shore Limited
- Take the bus from Boston, MA - South Station to Portland, MEbus Logan Airport / ...
14h 58m$160–419Fly Buffalo Niagara International Airport to Boston Logan Airport, bus
- Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane BUF - BOS
- Take the bus from Logan International Airport to Portland, MEbus
5h 18m$108–608Fly Buffalo Niagara International Airport to Augusta State Airport, bus
- Fly from Buffalo Niagara International Airport (BUF) to Augusta State Airport (AUG)plane BUF - AUG
- Take the bus from Augusta Transportation Center to Portland Transportation Centerbus
6h 46m$105–513Bus to Rochester, fly to Boston Logan Airport, bus
- Take the bus from Buffalo to Rochester Bus Stopbus
- Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane ROC - BOS
- Take the bus from Logan International Airport to Portland, MEbus
6h 52m$280–876Bus via Ithaca
- Take the bus from Buffalo to Ithacabus
- Take the bus from Ithaca to Bostonbus
- Take the bus from Boston, MA - South Station to Portland, MEbus
14h 54m$93–166
Buffalo to Portland, ME by bus
Questions & Answers
The cheapest way to get from Buffalo to Portland, ME is to bus via Ithaca which costs $90 - $170 and takes 14h 54m.
The fastest way to get from Buffalo to Portland, ME is to fly and bus which takes 5h 18m and costs $100 - $650.
No, there is no direct bus from Buffalo to Portland, ME. However, there are services departing from Buffalo and arriving at Portland, ME via Boston, MA - South Station. The journey, including transfers, takes approximately 12h 19m.
The distance between Buffalo and Portland, ME is 442 miles. The road distance is 511 miles.
The best way to get from Buffalo to Portland, ME without a car is to bus which takes 12h 19m and costs $95 - $190.
It takes approximately 5h 23m to get from Buffalo to Portland, ME, including transfers.
Buffalo to Portland, ME bus services, operated by Greyhound USA, depart from Buffalo station.
The best way to get from Buffalo to Portland, ME is to fly which takes 5h 23m and costs $120 - $800. Alternatively, you can bus, which costs $95 - $190 and takes 12h 19m.
Buffalo to Portland, ME bus services, operated by Greyhound USA, arrive at Boston station.
Yes, the driving distance between Buffalo to Portland, ME is 511 miles. It takes approximately 10h 20m to drive from Buffalo to Portland, ME.
What companies run services between Buffalo, NY, USA and Portland, ME, USA?
Southwest Airlines, JetBlue Airways, and three other airlines fly from Buffalo Niagara International Airport (BUF) to Portland (PWM) hourly. Alternatively, you can take a bus from Buffalo to Portland, ME via Boston and Boston, MA - South Station in around 12h 19m.
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Portland via Philadelphia
- Ave. Duration
- 4h 31m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $130–800
Flights from Buffalo Niagara International Airport to Portland via New York La Guardia
- Ave. Duration
- 3h 59m
- When
- Monday to Friday
- Estimated price
- $120–750
Flights from Buffalo Niagara International Airport to Portland via Reagan Washington
- Ave. Duration
- 4h 4m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–850
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $80–550
Flights from Rochester to Boston Logan Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $65–440
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to Portland via New York JFK
- Ave. Duration
- 3h 42m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–750
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $80–550
Flights from Buffalo Niagara International Airport to Augusta State Airport via Boston Logan Airport
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $70–420
Flights from Buffalo Niagara International Airport to Augusta State Airport via New York JFK, Boston Logan Airport
- Ave. Duration
- 7h 56m
- When
- Monday and Sunday
- Estimated price
- $75–440
Flights from Buffalo Niagara International Airport to Augusta State Airport via New York La Guardia, Boston Logan Airport
- Ave. Duration
- 5h 47m
- When
- Monday to Friday
- Estimated price
- $75–440
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Portland via Baltimore
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $140–800
Flights from Buffalo Niagara International Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 37m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $110–650
Flights from Rochester to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 37m
- When
- Monday to Friday
- Estimated price
- $95–550
- Website
- united.com
Flights from Buffalo Niagara International Airport to Portland via Washington Dulles
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $150–850
Flights from Buffalo Niagara International Airport to Portland via Newark
- Ave. Duration
- 4h 27m
- When
- Monday to Wednesday
- Estimated price
- $120–750
Flights from Rochester to Boston Logan Airport via Newark
- Ave. Duration
- 3h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $75–470
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Portland via Detroit
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $170–900
Flights from Buffalo Niagara International Airport to Portland via New York La Guardia
- Ave. Duration
- 4h 55m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–750
Flights from Buffalo Niagara International Airport to Portland via New York JFK
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $120–750
Flights from Rochester to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 3h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $70–470
- Website
- capeair.com
Flights from Buffalo Niagara International Airport to Augusta State Airport via Boston Logan Airport
- Ave. Duration
- 5h 44m
- When
- Monday to Saturday
- Estimated price
- $70–420
Flights from Buffalo Niagara International Airport to Augusta State Airport via New York La Guardia, Boston Logan Airport
- Ave. Duration
- 5h 47m
- When
- Monday to Friday
- Estimated price
- $75–440
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo Depew Station to Boston
- Ave. Duration
- 11h 27m
- Frequency
- Once daily
- Estimated price
- $130–300
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Buffalo to Boston
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $75–150
- Website
- https://www.greyhound.com/
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $12–23
- Website
- https://www.greyhound.com/
- Phone
- +1 800 639 3317
- info@concordcoachlines.com
- Website
- concordcoachlines.com
Bus from Boston, MA - South Station to Portland, ME
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $22–30
- Website
- https://concordcoachlines.com
Bus from Logan International Airport to Portland, ME
- Ave. Duration
- 2h 10m
- Frequency
- Hourly
- Estimated price
- $22–30
- Website
- https://concordcoachlines.com
Bus from Augusta Transportation Center to Portland Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- Every 2 hours
- Estimated price
- $13–17
- Website
- https://concordcoachlines.com
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Boston, MA - South Station to Portland, ME
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $21–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $21–45
Bus from Augusta Transportation Center to Portland Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- 5 times a day
- Estimated price
- $13–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $13–45
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- Every 3 hours
- Estimated price
- $9–17
- Schedules at
- flixbus.com
Bus from Buffalo to Ithaca
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- $21–40
- Schedules at
- flixbus.com
Bus from Ithaca to Boston
- Ave. Duration
- 7h 55m
- Frequency
- 5 times a week
- Estimated price
- $50–85
- Schedules at
- flixbus.com
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