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How to get fromBuffalo to Natickby plane, train, bus (Greyhound, Flixbus), train (Amtrak), car, bus or bus (Flixbus)

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There are 6 ways to get from Buffalo to Natick by plane, train, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport, train

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)planeBUF - BOS
    2. Take the train from Back Bay to Natick Centertrain
    4h 28m
    $116–748

  2. Train (Amtrak)

    cheapest
    1. Take the train from Buffalo Depew Station to Framingham AmtraktrainLake Shore Limited
    13h
    $56–242

  3. Bus via Springfield

    1. Take the bus from Buffalo to Syracuse Bus Stationbus
    2. Take the bus from Syracuse Bus Station to Springfield Union Stationbus
    3. Take the bus from Springfield Union Station to Framinghambus
    11h 35m
    $95–271

  4. Drive 438.7 mi

    1. Drive from Buffalo to Natickcar438.7 mi
    7h 37m
    $81–116

  5. Bus to Rochester, fly

    1. Take the bus from Buffalo, NY to Rochester, NYbus
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)planeROC - BOS
    6h 39m
    $226–653

  6. Bus (Flixbus)

    1. Take the bus from Buffalo to IthacabusFlixBus 2685
    2. Take the bus from Ithaca to BostonbusFlixBus 2691
    13h 55m
    $104–197

Buffalo to Natick by bus and train

Calendar14Weekly Services
Duration11h 35mAverage Duration
Ticket$95Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Natick, MA, USA?

You can take a bus from Buffalo to Natick Center via Syracuse Bus Station, Springfield Union Station, Framingham, and Framingham in around 11h 35m. Alternatively, Amtrak operates a train from Buffalo Depew Station to Framingham Amtrak once daily. Tickets cost $45–160 and the journey takes 10h 53m.

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