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How to get fromBuffalo to Murrells Inletby plane, bus (Greyhound, Flixbus), train, car or bus

Find Transport to Murrells Inlet

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There are 6 ways to get from Buffalo to Murrells Inlet by plane, bus (Greyhound, Flixbus), train, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR)plane plane BUF - MYR
    5h 36m
    $154–780

  2. Drive 770.6 mi

    cheapest
    1. Drive from Buffalo to Murrells Inletcar car 770.6 mi
    15h 56m
    $141–204

  3. Bus

    1. Take the bus from Buffalo, NY to Robert K Pfaff Transit Center - Akronbus bus
    2. Take the bus from Robert K Pfaff Transit Center - Akron to Charleston, WVbus bus
    3. Take the bus from Charleston, WV to Charlotte Bus Stationbus bus
    4. Take the bus from Charlotte Bus Station to Florence Bus Stationbus bus
    5. Take the bus from Florence to Myrtle Beach, SCbus bus
    21h 41m
    $145–396

  4. Train, drive (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Kingstree Stationtrain train
    3. Drive from Kingstree Station to Murrells Inletcar car
    23h 27m
    $186–534

  5. Bus to Rochester, fly

    1. Take the bus from Buffalo, NY to Rochester, NYbus bus
    2. Fly from Rochester (ROC) to Myrtle Beach (MYR)plane plane ROC - MYR
    5h 46m
    $194–595

  6. Bus via Chesapeake

    1. Take the bus from Buffalo to Pittsburghbus bus
    2. Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Norfolkbus bus
    4. Take the bus from Norfolk to Myrtle Beach Bus Stationbus bus
    29h 36m
    $199–465

Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR) flights

Calendar63Weekly Planes
Duration5h 53mAverage Duration
Ticket$112Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Murrells Inlet, SC, USA?

Southwest Airlines, American Airlines, and Delta fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR) every 3 hours. Alternatively, you can take a bus from Buffalo, NY to Murrells Inlet via Robert K Pfaff Transit Center - Akron, Charleston, WV, Charlotte Bus Station, Florence Bus Station, Florence, and Myrtle Beach, SC in around 21h 41m.

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