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How to get fromBuffalo to Murrells Inletby plane, bus (Greyhound, Flixbus), train, car or bus

Find Transport to Murrells Inlet

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There are 6 ways to get from Buffalo to Murrells Inlet by plane, bus (Greyhound, Flixbus), train, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR)planeBUF - MYR
    5h 30m
    $144–730

  2. Drive 771.5 mi

    cheapest
    1. Drive from Buffalo to Murrells Inletcar771.5 mi
    15h 47m
    $141–204

  3. Bus

    1. Take the bus from Buffalo, NY to Akron, OHbus
    2. Take the bus from Akron, OH to Charleston, WVbus
    3. Take the bus from Charleston, WV to Charlotte Bus Stationbus
    4. Take the bus from Charlotte Bus Station to Florence Bus Stationbus
    5. Take the bus from Florence to Myrtle Beach, SCbus
    21h 41m
    $155–391

  4. Train, drive (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Kingstree Stationtrain
    3. Drive from Kingstree Station to Murrells Inletcar
    23h 27m
    $155–382

  5. Bus to Rochester, fly

    1. Take the bus from Buffalo, NY to Rochester, NYbus
    2. Fly from Rochester (ROC) to Myrtle Beach (MYR)planeROC - MYR
    5h 45m
    $194–485

  6. Bus via Chesapeake

    1. Take the bus from Buffalo to Pittsburghbus
    2. Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus
    3. Take the bus from Washington Union Station to Norfolkbus
    4. Take the bus from Norfolk to Myrtle Beach Bus Stationbus
    29h 36m
    $199–495

Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR) flights

Calendar74Weekly Planes
Duration5h 17mAverage Duration
Ticket$107Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Murrells Inlet, SC, USA?

Southwest Airlines, Delta, and American Airlines fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR) every 2 hours. Alternatively, you can take a bus from Buffalo, NY to Murrells Inlet via Akron, OH, Charleston, WV, Charlotte Bus Station, Florence Bus Station, Florence, and Myrtle Beach, SC in around 21h 41m.

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