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How to get fromBuffalo to Murrells Inletby plane, train, bus, bus (Flixbus, Greyhound), or car

Find Transport to Murrells Inlet

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There are 8 ways to get from Buffalo to Murrells Inlet by plane, train, bus, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR)plane plane BUF - MYR
    5h 32m
    $107–432

  2. Train, bus via Washington

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Washington Union Stationtrain train
    3. Take the train from Washington Union Station to Fayetteville Amtrak Stationtrain train
    4. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    22h 55m
    $608–937

  3. Bus

    1. Take the bus from Buffalo to Newark Penn Stationbus bus
    2. Take the bus from Newark Penn Station to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Myrtle Beach Bus Stationbus bus
    23h 41m
    $205–342

  4. Drive  771.8 mi

    1. Drive from Buffalo to Murrells Inletcar car 771.8 mi
    15h 53m
    $141–204

  5. Bus to Rochester, fly

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Myrtle Beach (MYR)plane plane ROC - MYR
    5h 6m
    $159–642

  6. Train, bus

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Fayetteville Amtrak Stationtrain train
    3. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    24h 30m
    $608–937

  7. Train, drive (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Kingstree Stationtrain train
    3. Drive from Kingstree Station to Murrells Inletcar car
    26h 8m
    $624–989

  8. Bus, train

    1. Take the bus from Buffalo, Ny to Pittsburgh, Pabus bus 530
    2. Take the train from Pittsburgh Amtrak Station to Richmond Staples Mill Road Amtrak Stationtrain train
    3. Take the train from Richmond Staples Mill Road Amtrak Station to Fayetteville Amtrak Stationtrain train
    4. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    27h 56m
    $456–838

Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR) flights

Calendar95Weekly Planes
Duration4h 43mAverage Duration
Ticket$67Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Murrells Inlet.ExpandLaunch map view
  • Distance: 664.7 mi
  • Duration: 5h 32m

What companies run services between Buffalo, NY, USA and Murrells Inlet, SC, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR) hourly. Alternatively, you can take a bus from Buffalo to Murrells Inlet via Newark Penn Station, Raleigh Bus Station, and Myrtle Beach Bus Station in around 23h 41m.

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