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How to get fromBuffalo to Murrells Inletby plane, train, car, bus (Flixbus, Greyhound), bus or bus (Greyhound)

Find Transport to Murrells Inlet

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There are 6 ways to get from Buffalo to Murrells Inlet by plane, train, car, bus (Flixbus, Greyhound), bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR)plane plane BUF - MYR
    5h 16m
    $146–678

  2. Drive 770.9 mi

    cheapest
    1. Drive from Buffalo to Murrells Inletcar car 770.9 mi
    15h 55m
    $141–204

  3. Train, drive (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Kingstree Stationtrain train
    3. Drive from Kingstree Station to Murrells Inletcar car
    23h 27m
    $260–592

  4. Bus

    1. Take the bus from Buffalo to Newark Penn Stationbus bus
    2. Take the bus from Newark Penn Station to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Wilmington Cape Fear Public Transitbus bus
    4. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    25h 26m
    $184–394

  5. Bus to Rochester, fly

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Myrtle Beach (MYR)plane plane ROC - MYR
    4h 50m
    $187–695

  6. Bus via Chesapeake

    1. Take the bus from Buffalo to New Yorkbus bus
    2. Take the bus from Times Square – 37th St. to Norfolk, VA - Best Squarebus bus
    3. Take the bus from Norfolk to Myrtle Beach Bus Stationbus bus
    26h 27m
    $212–498

Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR) flights

Calendar59Weekly Planes
Duration4h 58mAverage Duration
Ticket$107Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Murrells Inlet, SC, USA?

Southwest Airlines, American Airlines, and Delta fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a bus from Buffalo to Murrells Inlet via Newark Penn Station, Raleigh Bus Station, Wilmington Cape Fear Public Transit, and Myrtle Beach Bus Station in around 25h 26m.

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