There are 6 ways to get from Buffalo to Middleborough by plane, train, bus, train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Buffalo Niagara International Airport, train
best- Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane BUF - BOS
- Take the train from South Station to Middleboroughtrain
5h 27m$102–692Bus, train
cheapest- Take the bus from Buffalo to Syracuse Bus Stationbus
- Take the bus from Syracuse Bus Station to Bostonbus
- Take the train from South Station to Middleboroughtrain
13h 21m$59–174Train
- Take the train from Buffalo Depew Station to Bostontrain Lake Shore Limited
- Take the train from South Station to Middleboroughtrain Fall River/New Bedford Line
14h 35m$143–376Drive 472.4 mi
- Drive from Buffalo to Middleboroughcar 472.4 mi
8h 12m$87–125Bus to Rochester, fly, train
- Take the bus from Buffalo to Rochester Bus Stopbus
- Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane ROC - BOS
- Take the train from South Station to Middleboroughtrain
6h 6m$242–837Bus, train via New York
- Take the bus from Buffalo to New Yorkbus
- Take the bus from Times Square – 37th St. to Burgin Pkwy @ Quincy Center Stationbus
- Take the train from Quincy Center to Middleboroughtrain
15h 7m$84–334
Buffalo to Middleborough by bus and train
Questions & Answers
The cheapest way to get from Buffalo to Middleborough is to drive which costs $85 - $130 and takes 8h 12m.
The fastest way to get from Buffalo to Middleborough is to fly and train which takes 5h 27m and costs $100 - $700.
No, there is no direct train from Buffalo to Middleborough. However, there are services departing from Buffalo and arriving at Middleborough via Buffalo Depew Station and South Station. The journey, including transfers, takes approximately 14h 35m.
The distance between Buffalo and Middleborough is 451 miles. The road distance is 475.1 miles.
The best way to get from Buffalo to Middleborough without a car is to bus and train which takes 13h 21m and costs $55 - $180.
It takes approximately 5h 27m to get from Buffalo to Middleborough, including transfers.
Buffalo to Middleborough train services, operated by Amtrak, depart from Buffalo Depew Station.
Buffalo to Middleborough train services, operated by Amtrak, arrive at Boston station.
Yes, the driving distance between Buffalo to Middleborough is 475 miles. It takes approximately 8h 12m to drive from Buffalo to Middleborough.
There are 150+ hotels available in Middleborough.
What companies run services between Buffalo, NY, USA and Middleborough, MA, USA?
You can take a train from Buffalo to Middleborough via Buffalo Depew Station, Boston, and South Station in around 14h 35m.
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $95–650
Flights from Rochester to Boston Logan Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $70–480
Flights from Rochester to Boston Logan Airport via Philadelphia
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- $90–550
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 40m
- When
- Monday to Saturday
- Estimated price
- $120–750
Flights from Rochester to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 45m
- When
- Tuesday and Wednesday
- Estimated price
- $100–600
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $95–650
- Website
- united.com
Flights from Rochester to Boston Logan Airport via Newark
- Ave. Duration
- 3h 49m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–550
- Phone
- +1-617-222-3200
- Website
- mbta.com
Train from South Station to Middleborough
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- $4–13
- Website
- https://www.mbta.com
- Adult
- $4–13
Train from Quincy Center to Middleborough
- Ave. Duration
- 49 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- https://www.mbta.com
- Adult
- $4–11
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo Depew Station to Boston
- Ave. Duration
- 11h 27m
- Frequency
- Once daily
- Estimated price
- $130–290
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 2h 50m
- Frequency
- Every 4 hours
- Estimated price
- $19–35
- Schedules at
- flixbus.com
Bus from Syracuse Bus Station to Boston
- Ave. Duration
- 6h 30m
- Frequency
- 5 times a week
- Estimated price
- $35–70
- Schedules at
- flixbus.com
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 15m
- Frequency
- Every 3 hours
- Estimated price
- $9–16
- Schedules at
- flixbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Every 4 hours
- Estimated price
- $28–95
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $28–90
- Flexible
- $55–95
Bus from Buffalo to New York
- Ave. Duration
- 7h 55m
- Frequency
- 4 times a day
- Estimated price
- $60–280
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $60–260
- Flexible
- $110–280
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 3h 5m
- Frequency
- 4 times a day
- Estimated price
- $27–55
- Website
- https://www.greyhound.com/
Bus from Syracuse Bus Station to Boston
- Ave. Duration
- 7h 40m
- Frequency
- Once daily
- Estimated price
- $55–110
- Website
- https://www.greyhound.com/
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 25m
- Frequency
- 3 times a day
- Estimated price
- $12–24
- Website
- https://www.greyhound.com/
- Phone
- +1 617-681-0820
- support@coachrun.com
- Website
- coachrun.com
Bus from Times Square – 37th St. to Burgin Pkwy @ Quincy Center Station
- Ave. Duration
- 4h 30m
- Frequency
- Twice a week
- Estimated price
- $18–50
- Website
- https://www.coachrun.com
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