There are 6 ways to get from Buffalo to Mesa by plane, train, bus, bus (Greyhound), car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Buffalo Niagara International Airport
best- Fly from Buffalo Niagara International Airport (BUF) to Phoenix (PHX)plane BUF - PHX
7h 21m$306–1,482Bus
cheapest- Take the bus from Buffalo, NY to Columbus - Mound Stbus
- Take the bus from Columbus to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Phoenix Bus Stationbus
2d 3h$203–712Train, bus via Flagstaff
- Take the train from Buffalo Depew Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Flagstafftrain
- Take the bus from Flagstaff Train Station to Phoenix Sky Harbor Airport/44th Street Sky Train Stationbus
2d$256–777Drive 2,175.6 mi
- Drive from Buffalo to Mesacar 2,175.6 mi
35h 32m$397–574Shuttle to Toronto Pearson International Airport, fly
- Take a shuttle bus from Buffalo Airport to Pearson International Airport Terminal 1
- Fly from Toronto Pearson International Airport (YYZ) to Phoenix (PHX)plane YYZ - PHX
10h 40m$271–902Train, bus
- Take the train from Buffalo Depew Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Tucson Amtrak Stationtrain
- Take the bus from Tucson Downtown to Tempebus
3d 1h$256–1,156
Buffalo to Mesa by train, bus, and tram
Questions & Answers
The cheapest way to get from Buffalo to Mesa is to bus which costs $200 - $750 and takes 2 days 3h.
The fastest way to get from Buffalo to Mesa is to fly which takes 7h 21m and costs $300 - $1,500.
No, there is no direct bus from Buffalo to Mesa. However, there are services departing from Buffalo, NY and arriving at University Dr & Mesa Dr via Columbus, St Louis Bus Station, Phoenix Bus Station, Phoenix Sky Harbor Airport/44th Street Sky Train Station and University Dr & Rural Rd. The journey, including transfers, takes approximately 2 days 3h.
The distance between Buffalo and Mesa is 1941 miles. The road distance is 2188.3 miles.
The best way to get from Buffalo to Mesa without a car is to train and bus via Flagstaff which takes 2 days 0h and costs $250 - $800.
It takes approximately 7h 21m to get from Buffalo to Mesa, including transfers.
Buffalo to Mesa bus services, operated by Barons Bus, depart from Buffalo, NY station.
The best way to get from Buffalo to Mesa is to fly which takes 7h 21m and costs $300 - $1,500. Alternatively, you can bus, which costs $200 - $750 and takes 2 days 3h.
Buffalo to Mesa bus services, operated by Barons Bus, arrive at Columbus - Mound St station.
Mesa is 2h behind Buffalo. It is currently 6:50 PM in Buffalo and 4:50 PM in Mesa.
What companies run services between Buffalo, NY, USA and Mesa, AZ, USA?
Southwest Airlines, Delta, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Phoenix (PHX) every 3 hours. Alternatively, you can take a bus from Buffalo, NY to University Dr & Mesa Dr via Columbus, St Louis Bus Station, Phoenix Bus Station, Phoenix Sky Harbor Airport/44th Street Sky Train Station, Tempe, and University Dr & Rural Rd in around 2d 3h.
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Phoenix via Minneapolis
- Ave. Duration
- 6h 36m
- When
- Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $310–1,400
Flights from Buffalo Niagara International Airport to Phoenix via Detroit
- Ave. Duration
- 7h 13m
- When
- Every day
- Estimated price
- $300–1,400
Flights from Toronto Pearson International Airport to Phoenix via Detroit
- Ave. Duration
- 8h 10m
- When
- Every day
- Estimated price
- $160–750
Flights from Toronto Pearson International Airport to Phoenix via Minneapolis
- Ave. Duration
- 9h 11m
- When
- Every day
- Estimated price
- $160–750
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Phoenix
- Ave. Duration
- 5h 12m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $300–1,400
Flights from Buffalo Niagara International Airport to Phoenix via Dallas
- Ave. Duration
- 6h 55m
- When
- Saturday
- Estimated price
- $320–1,400
Flights from Buffalo Niagara International Airport to Phoenix via Chicago Midway
- Ave. Duration
- 7h
- When
- Monday to Friday
- Estimated price
- $300–1,400
Flights from Buffalo Niagara International Airport to Phoenix via Denver
- Ave. Duration
- 7h 5m
- When
- Monday, Thursday, and Friday
- Estimated price
- $300–1,400
Flights from Buffalo Niagara International Airport to Phoenix via Nashville
- Ave. Duration
- 7h 57m
- When
- Monday to Friday
- Estimated price
- $320–1,400
- Website
- united.com
Flights from Buffalo Niagara International Airport to Phoenix via Denver
- Ave. Duration
- 7h 5m
- When
- Every day
- Estimated price
- $300–1,400
Flights from Buffalo Niagara International Airport to Phoenix via Chicago O'Hare
- Ave. Duration
- 7h 34m
- When
- Every day
- Estimated price
- $300–1,400
Flights from Toronto Pearson International Airport to Phoenix via Denver
- Ave. Duration
- 7h 19m
- When
- Every day
- Estimated price
- $160–750
- Website
- aircanada.com
Flights from Buffalo Niagara International Airport to Phoenix via Chicago O'Hare
- Ave. Duration
- 7h 34m
- When
- Every day
- Estimated price
- $300–1,400
Flights from Toronto Pearson International Airport to Phoenix
- Ave. Duration
- 4h 59m
- When
- Every day
- Estimated price
- $160–750
Flights from Toronto Pearson International Airport to Phoenix via Denver
- Ave. Duration
- 7h 19m
- When
- Every day
- Estimated price
- $160–750
- Website
- suncountry.com
Flights from Buffalo Niagara International Airport to Phoenix via Minneapolis
- Ave. Duration
- 7h 56m
- When
- Thursday
- Estimated price
- $310–1,400
- Website
- flyporter.com
Flights from Toronto Pearson International Airport to Phoenix
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $170–700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo Depew Station to Chicago Union Station
- Ave. Duration
- 10h 33m
- Frequency
- Twice daily
- Estimated price
- $65–210
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Flagstaff
- Ave. Duration
- 31h 44m
- Frequency
- Twice daily
- Estimated price
- $150–440
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Tucson Amtrak Station
- Ave. Duration
- 2d 8h
- Frequency
- 3 times a week
- Estimated price
- $160–900
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Flagstaff Train Station to Phoenix Sky Harbor Airport/44th Street Sky Train Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $30–50
- Schedules at
- flixbus.com
Bus from Tucson Downtown to Tempe
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a day
- Estimated price
- $25–40
- Schedules at
- flixbus.com
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Buffalo, NY to Columbus - Mound St
- Ave. Duration
- 7h 5m
- Frequency
- Once daily
- Estimated price
- $35–80
- Website
- https://baronsbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Columbus to St Louis Bus Station
- Ave. Duration
- 9h 5m
- Frequency
- 3 times a day
- Estimated price
- $50–110
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Phoenix Bus Station
- Ave. Duration
- 30h
- Frequency
- Twice daily
- Estimated price
- $110–360
- Website
- https://www.greyhound.com/
- Phone
- 905-374-8111
- airsales@niagaraairbus.com
- Website
- niagaraairbus.com
Shuttle from Buffalo Airport to Pearson International Airport Terminal 1
- Ave. Duration
- 2h
- Frequency
- On demand
- Estimated price
- $95–120
- Website
- https://www.niagaraairbus.com
- Schedules at
- https://www.niagaraairbus.com
- Book at
- https://www.niagaraairbus.com
Want to know more about travelling around United States
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More Questions & Answers
Yes, the driving distance between Buffalo to Mesa is 2188 miles. It takes approximately 35h 32m to drive from Buffalo to Mesa.
There are 2608+ hotels available in Mesa.















