There are 6 ways to get from Buffalo to Lowell by plane, train, bus (Flixbus, Greyhound), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Buffalo Niagara International Airport, train
best- Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane BUF - BOS
- Take the train from Anderson/Woburn to Lowelltrain
4h 37m$118–745Bus
cheapest- Take the bus from Buffalo to Syracuse Bus Stationbus
- Take the bus from Syracuse Bus Station to Bostonbus
- Take the bus from Boston to Robert B Kennedy Bus Transfer Centerbus
13h 15m$58–151Train
- Take the train from Buffalo Depew Station to Bostontrain Lake Shore Limited
- Take the train from North Station to Lowelltrain Lowell Line
14h 19m$116–339Drive 435.7 mi
- Drive from Buffalo to Lowellcar 435.7 mi
8h 43m$80–115Bus to Rochester, fly
- Take the bus from Buffalo to Rochester Bus Stopbus
- Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane ROC - BOS
5h 50m$239–712Bus, train
- Take the bus from Buffalo to New Yorkbus
- Take the bus from New York, NY - W 42nd Street and 9th Avenue to Boston, MA - Dalton and Belvidere Streetbus
- Take the train from North Station to Lowelltrain
14h 47m$89–362
Buffalo to Lowell by bus
Questions & Answers
The cheapest way to get from Buffalo to Lowell is to bus which costs $55 - $160 and takes 13h 15m.
The fastest way to get from Buffalo to Lowell is to fly and train which takes 4h 37m and costs $110 - $750.
No, there is no direct bus from Buffalo to Lowell. However, there are services departing from Buffalo and arriving at Robert B Kennedy Bus Transfer Center via Syracuse Bus Station and Boston. The journey, including transfers, takes approximately 13h 15m.
No, there is no direct train from Buffalo to Lowell. However, there are services departing from Buffalo and arriving at Lowell via Buffalo Depew Station, Back Bay and North Station. The journey, including transfers, takes approximately 14h 19m.
The distance between Buffalo and Lowell is 435 miles. The road distance is 438.2 miles.
The best way to get from Buffalo to Lowell without a car is to bus which takes 13h 15m and costs $55 - $160.
It takes approximately 4h 37m to get from Buffalo to Lowell, including transfers.
Buffalo to Lowell bus services, operated by Flixbus USA, depart from Buffalo station.
Buffalo to Lowell train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from Buffalo to Lowell is to bus which takes 13h 15m and costs $55 - $160. Alternatively, you can train, which costs $110 - $340 and takes 14h 19m.
What companies run services between Buffalo, NY, USA and Lowell, MA, USA?
You can take a bus from Buffalo to Robert B Kennedy Bus Transfer Center via Syracuse Bus Station and Boston in around 13h 15m. Alternatively, you can take a train from Buffalo to Lowell via Buffalo Depew Station, Boston, Back Bay, North Station, and North Station in around 14h 19m.
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 31m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–700
Flights from Rochester to Boston Logan Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $80–550
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $100–700
Flights from Buffalo Niagara International Airport to Boston Logan Airport via New York JFK
- Ave. Duration
- 3h 48m
- When
- Monday, Tuesday, Wednesday, and Sunday
- Estimated price
- $110–750
Flights from Rochester to Boston Logan Airport via New York JFK
- Ave. Duration
- 3h 53m
- When
- Tuesday
- Estimated price
- $90–600
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 35m
- When
- Saturday
- Estimated price
- $130–800
Flights from Rochester to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 47m
- When
- Monday to Saturday
- Estimated price
- $110–650
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 3h 48m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–750
Flights from Rochester to Boston Logan Airport via New York JFK
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $90–600
- Website
- united.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport via Newark
- Ave. Duration
- 3h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–750
- Phone
- +1-617-222-3200
- Website
- mbta.com
Train from Anderson/Woburn to Lowell
- Ave. Duration
- 24 min
- Frequency
- Hourly
- Estimated price
- $3–8
- Website
- https://www.mbta.com
- Adult
- $3–8
Train from North Station to Lowell
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- https://www.mbta.com
- Adult
- $4–11
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo Depew Station to Boston
- Ave. Duration
- 11h 19m
- Frequency
- Once daily
- Estimated price
- $100–250
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 2h 50m
- Frequency
- Every 4 hours
- Estimated price
- $18–35
- Schedules at
- flixbus.com
Bus from Syracuse Bus Station to Boston
- Ave. Duration
- 6h 30m
- Frequency
- 5 times a week
- Estimated price
- $35–65
- Schedules at
- flixbus.com
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 15m
- Frequency
- Every 3 hours
- Estimated price
- $8–15
- Schedules at
- flixbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Every 4 hours
- Estimated price
- $28–95
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $28–90
- Flexible
- $55–95
Bus from Buffalo to New York
- Ave. Duration
- 7h 55m
- Frequency
- 5 times a day
- Estimated price
- $60–280
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $60–260
- Flexible
- $110–280
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 3h 5m
- Frequency
- 4 times a day
- Estimated price
- $25–50
- Website
- https://www.greyhound.com/
Bus from Syracuse Bus Station to Boston
- Ave. Duration
- 7h 40m
- Frequency
- Once daily
- Estimated price
- $50–95
- Website
- https://www.greyhound.com/
Bus from Boston to Robert B Kennedy Bus Transfer Center
- Ave. Duration
- 45 min
- Frequency
- 5 times a week
- Estimated price
- $4–9
- Website
- https://www.greyhound.com/
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 25m
- Frequency
- 3 times a day
- Estimated price
- $12–22
- Website
- https://www.greyhound.com/
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from New York, NY - W 42nd Street and 9th Avenue to Boston, MA - Dalton and Belvidere Street
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $20–75
- Website
- https://www.ourbus.com
Want to know more about travelling around United States
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More Questions & Answers
Buffalo to Lowell bus services, operated by Flixbus USA, arrive at Syracuse Bus Station.
Buffalo to Lowell train services, operated by Amtrak, arrive at Boston station.
Yes, the driving distance between Buffalo to Lowell is 438 miles. It takes approximately 8h 43m to drive from Buffalo to Lowell.
Book your Buffalo to Lowell bus tickets online with Omio and FlixBus.
There are 120+ hotels available in Lowell.

















