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How to get fromBuffalo to Lowellby plane, train, bus (Flixbus, Greyhound), train (Amtrak), car or bus

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There are 6 ways to get from Buffalo to Lowell by plane, train, bus (Flixbus, Greyhound), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport, train

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)planeBUF - BOS
    2. Take the train from Anderson/Woburn to Lowelltrain
    4h 38m
    $116–747
  2. Bus, train

    cheapest
    1. Take the bus from Buffalo to Ithacabus
    2. Take the bus from Ithaca, NY to Boston, MAbus
    3. Take the train from North Station to Lowelltrain
    14h 23m
    $63–187
  3. Bus

    1. Take the bus from Buffalo to Syracuse Bus Stationbus
    2. Take the bus from Syracuse Bus Station to Bostonbus
    3. Take the bus from Boston to Robert B Kennedy Bus Transfer Centerbus
    12h 30m
    $81–183
  4. Train

    1. Take the train from Buffalo Depew Station to BostontrainLake Shore Limited
    2. Take the train from North Station to LowelltrainLowell Line
    14h 17m
    $126–528
  5. Drive 435.7 mi

    1. Drive from Buffalo to Lowellcar435.7 mi
    8h 40m
    $80–115
  6. Bus to Rochester, fly

    1. Take the bus from Buffalo, NY to Rochester, NYbus
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)planeROC - BOS
    6h 49m
    $226–652

Buffalo to Lowell by bus

Calendar5Weekly Buses
Duration12h 30mAverage Duration
Ticket$81Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Lowell, MA, USA?

You can take a bus from Buffalo to Robert B Kennedy Bus Transfer Center via Syracuse Bus Station and Boston in around 12h 30m. Alternatively, you can take a train from Buffalo to Lowell via Buffalo Depew Station, Boston, Back Bay, North Station, and North Station in around 14h 17m.

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