There are 6 ways to get from Buffalo to Lowell by plane, train, bus (Greyhound), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Buffalo Niagara International Airport, train
best- Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane BUF - BOS
- Take the train from Anderson/Woburn to Lowelltrain
4h 26m$107–645Bus, train
cheapest- Take the bus from Buffalo to Ithacabus
- Take the bus from Ithaca to Bostonbus
- Take the train from North Station to Lowelltrain
14h 42m$71–137Bus (Greyhound)
- Take the bus from Buffalo to Bostonbus Greyhound US0171
- Take the bus from Boston to Robert B Kennedy Bus Transfer Centerbus Greyhound US0256S
11h 50m$81–156Train
- Take the train from Buffalo Depew Station to Bostontrain Lake Shore Limited
- Take the train from North Station to Lowelltrain Lowell Line
14h 12m$146–379Drive 435.7 mi
- Drive from Buffalo to Lowellcar 435.7 mi
8h 43m$80–115Bus to Rochester, fly
- Take the bus from Buffalo to Rochester Bus Stopbus
- Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane ROC - BOS
6h$269–814
Buffalo to Lowell by bus (Greyhound)
Questions & Answers
The cheapest way to get from Buffalo to Lowell is to bus which costs $80 - $160 and takes 11h 50m.
The fastest way to get from Buffalo to Lowell is to fly and train which takes 4h 26m and costs $100 - $650.
No, there is no direct bus from Buffalo to Lowell. However, there are services departing from Buffalo and arriving at Robert B Kennedy Bus Transfer Center via Boston. The journey, including transfers, takes approximately 11h 50m.
No, there is no direct train from Buffalo to Lowell. However, there are services departing from Buffalo and arriving at Lowell via Buffalo Depew Station, Back Bay and North Station. The journey, including transfers, takes approximately 14h 12m.
The distance between Buffalo and Lowell is 434 miles. The road distance is 438.2 miles.
The best way to get from Buffalo to Lowell without a car is to bus which takes 11h 50m and costs $80 - $160.
It takes approximately 4h 26m to get from Buffalo to Lowell, including transfers.
Buffalo to Lowell bus services, operated by Greyhound USA, depart from Buffalo station.
Buffalo to Lowell train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from Buffalo to Lowell is to bus which takes 11h 50m and costs $80 - $160. Alternatively, you can train, which costs $140 - $380 and takes 14h 12m.
What companies run services between Buffalo, NY, USA and Lowell, MA, USA?
You can take a bus from Buffalo to Robert B Kennedy Bus Transfer Center via Boston in around 11h 50m. Alternatively, you can take a train from Buffalo to Lowell via Buffalo Depew Station, Boston, Back Bay, North Station, and North Station in around 14h 12m.
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $90–600
Flights from Rochester to Boston Logan Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $65–450
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $90–600
- Website
- united.com
Flights from Rochester to Boston Logan Airport via Newark
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- $75–480
- Website
- southwest.com
Flights from Rochester to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 42m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–550
- Website
- delta.com
Flights from Rochester to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 3h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $75–480
- Phone
- +1-617-222-3200
- Website
- mbta.com
Train from Anderson/Woburn to Lowell
- Ave. Duration
- 24 min
- Frequency
- Hourly
- Estimated price
- $2–8
- Website
- https://www.mbta.com
- Adult
- $2–8
Train from North Station to Lowell
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- https://www.mbta.com
- Adult
- $4–11
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo Depew Station to Boston
- Ave. Duration
- 11h 19m
- Frequency
- Once daily
- Estimated price
- $130–290
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Buffalo to Boston
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $75–150
- Website
- https://www.greyhound.com/
Bus from Boston to Robert B Kennedy Bus Transfer Center
- Ave. Duration
- 45 min
- Frequency
- 5 times a week
- Estimated price
- $4–9
- Website
- https://www.greyhound.com/
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $12–24
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- Every 3 hours
- Estimated price
- $9–17
- Schedules at
- flixbus.com
Bus from Buffalo to Ithaca
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- $21–40
- Schedules at
- flixbus.com
Bus from Ithaca to Boston
- Ave. Duration
- 7h 55m
- Frequency
- 5 times a week
- Estimated price
- $45–85
- Schedules at
- flixbus.com
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More Questions & Answers
Buffalo to Lowell bus services, operated by Greyhound USA, arrive at Boston station.
Buffalo to Lowell train services, operated by Amtrak, arrive at Boston station.
Yes, the driving distance between Buffalo to Lowell is 438 miles. It takes approximately 8h 43m to drive from Buffalo to Lowell.
Book your Buffalo to Lowell bus tickets online with Omio and FlixBus.
There are 180+ hotels available in Lowell.













