There are 6 ways to get from Buffalo to Lowell by plane, train, bus (Flixbus, Greyhound), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Buffalo Niagara International Airport, train
best- Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)BUF - BOS
- Take the train from Anderson/Woburn to Lowell
4h 38m$116–747Bus, train
cheapest- Take the bus from Buffalo to Ithaca
- Take the bus from Ithaca, NY to Boston, MA
- Take the train from North Station to Lowell
14h 23m$63–187Bus
- Take the bus from Buffalo to Syracuse Bus Station
- Take the bus from Syracuse Bus Station to Boston
- Take the bus from Boston to Robert B Kennedy Bus Transfer Center
12h 30m$81–183Train
- Take the train from Buffalo Depew Station to BostonLake Shore Limited
- Take the train from North Station to LowellLowell Line
14h 17m$126–528Drive 435.7 mi
- Drive from Buffalo to Lowell435.7 mi
8h 40m$80–115Bus to Rochester, fly
- Take the bus from Buffalo, NY to Rochester, NY
- Fly from Rochester (ROC) to Boston Logan Airport (BOS)ROC - BOS
6h 49m$226–652
Buffalo to Lowell by bus
Questions & Answers
The cheapest way to get from Buffalo to Lowell is to drive which costs $75 - $120 and takes 8h 40m.
The fastest way to get from Buffalo to Lowell is to fly and train which takes 4h 38m and costs $110 - $750.
No, there is no direct bus from Buffalo to Lowell. However, there are services departing from Buffalo and arriving at Robert B Kennedy Bus Transfer Center via Syracuse Bus Station and Boston. The journey, including transfers, takes approximately 12h 30m.
No, there is no direct train from Buffalo to Lowell. However, there are services departing from Buffalo and arriving at Lowell via Buffalo Depew Station, Back Bay and North Station. The journey, including transfers, takes approximately 14h 17m.
The distance between Buffalo and Lowell is 435 miles. The road distance is 438.2 miles.
The best way to get from Buffalo to Lowell without a car is to bus which takes 12h 30m and costs $80 - $190.
It takes approximately 4h 38m to get from Buffalo to Lowell, including transfers.
Buffalo to Lowell bus services, operated by Flixbus USA, depart from Buffalo station.
Buffalo to Lowell train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from Buffalo to Lowell is to bus which takes 12h 30m and costs $80 - $190. Alternatively, you can train, which costs $120 - $550 and takes 14h 17m.
What companies run services between Buffalo, NY, USA and Lowell, MA, USA?
You can take a bus from Buffalo to Robert B Kennedy Bus Transfer Center via Syracuse Bus Station and Boston in around 12h 30m. Alternatively, you can take a train from Buffalo to Lowell via Buffalo Depew Station, Boston, Back Bay, North Station, and North Station in around 14h 17m.
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 32m
- When
- Sunday
- Estimated price
- $100–650
Flights from Buffalo Niagara International Airport to Boston Logan Airport via Philadelphia
- Ave. Duration
- 3h 43m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–700
Flights from Rochester to Boston Logan Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $75–480
Flights from Rochester to Boston Logan Airport via Philadelphia
- Ave. Duration
- 3h 56m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $90–550
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 35m
- When
- Friday
- Estimated price
- $120–700
Flights from Rochester to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 51m
- When
- Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $100–650
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 3h 40m
- When
- Monday to Friday
- Estimated price
- $110–650
Flights from Rochester to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 3h 48m
- When
- Monday to Friday
- Estimated price
- $85–500
- Website
- united.com
Flights from Rochester to Boston Logan Airport via Newark
- Ave. Duration
- 3h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $85–550
- Phone
- +1-617-222-3200
- Website
- mbta.com
Train from Anderson/Woburn to Lowell
- Ave. Duration
- 24 min
- Frequency
- Hourly
- Estimated price
- $3–8
- Website
- https://www.mbta.com
- Adult
- $3–8
Train from North Station to Lowell
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- https://www.mbta.com
- Adult
- $4–11
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo Depew Station to Boston
- Ave. Duration
- 11h 19m
- Frequency
- Once daily
- Estimated price
- $110–440
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- Every 4 hours
- Estimated price
- $27–40
- Schedules at
- flixbus.com
Bus from Syracuse Bus Station to Boston
- Ave. Duration
- 6h 20m
- Frequency
- 6 times a week
- Estimated price
- $45–130
- Schedules at
- flixbus.com
Bus from Buffalo to Ithaca
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $35–80
- Schedules at
- flixbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- 4 times a day
- Estimated price
- $27–40
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- 4 times a day
- Estimated price
- $27–40
- Website
- https://www.greyhound.com/
Bus from Syracuse Bus Station to Boston
- Ave. Duration
- 7h 40m
- Frequency
- Once daily
- Estimated price
- $45–120
- Website
- https://www.greyhound.com/
Bus from Boston to Robert B Kennedy Bus Transfer Center
- Ave. Duration
- 45 min
- Frequency
- 5 times a week
- Estimated price
- $9–14
- Website
- https://www.greyhound.com/
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Buffalo, NY to Rochester, NY
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $20–55
- Website
- https://www.ourbus.com
Bus from Ithaca, NY to Boston, MA
- Ave. Duration
- 7h 45m
- Frequency
- Once a week
- Estimated price
- $20–95
- Website
- https://www.ourbus.com
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More Questions & Answers
Buffalo to Lowell bus services, operated by Flixbus USA, arrive at Syracuse Bus Station.
Buffalo to Lowell train services, operated by Amtrak, arrive at Boston station.
Yes, the driving distance between Buffalo to Lowell is 438 miles. It takes approximately 8h 40m to drive from Buffalo to Lowell.
Book your Buffalo to Lowell bus tickets online with Omio and FlixBus.
There are 111+ hotels available in Lowell.


















