There are 6 ways to get from Buffalo to Lisle by plane, train, train (Amtrak), bus (Greyhound), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Buffalo Niagara International Airport to Chicago O'Hare International Airport, train
best- Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane BUF - ORD
- Take the train from Chicago Union Station to Lisletrain
5h 37m$85–551Bus
cheapest- Take the bus from Buffalo to Cleveland Bus Stationbus Greyhound US0170
- Take the bus from Cleveland Bus Station to Chicago Bus Stationbus Greyhound US0164
15h 8m$66–146Train (Amtrak)
- Take the train from Buffalo Depew Station to Chicago Union Stationtrain Lake Shore Limited
13h 8m$88–279Drive 549.5 mi
- Drive from Buffalo to Lislecar 549.5 mi
9h 31m$101–145Fly Buffalo Niagara International Airport to Chicago Midway International Airport, train
- Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane BUF - MDW
- Take the train from Chicago Union Station to Lisletrain
5h 27m$110–791Bus to Rochester, fly to Chicago O'Hare International Airport
- Take the bus from Buffalo, NY to Rochester, NYbus
- Fly from Rochester (ROC) to Chicago O'Hare International Airport (ORD)plane ROC - ORD
8h 1m$140–636
Buffalo to Lisle by train (Amtrak)
Questions & Answers
The cheapest way to get from Buffalo to Lisle is to bus which costs $65 - $150 and takes 15h 8m.
The fastest way to get from Buffalo to Lisle is to fly and train which takes 5h 27m and costs $110 - $800.
No, there is no direct bus from Buffalo to Lisle. However, there are services departing from Buffalo and arriving at Ogden Ave & Main St via Cleveland Bus Station, Harrison & Jefferson, Cicero & 24th Place, 54th Ave CTA Station/Pink Line and Yorktown Center. The journey, including transfers, takes approximately 15h 8m.
No, there is no direct train from Buffalo to Lisle. However, there are services departing from Buffalo and arriving at Lisle via Buffalo Depew Station and Chicago Union Station. The journey, including transfers, takes approximately 13h 8m.
The distance between Buffalo and Lisle is 528 miles. The road distance is 552.8 miles.
The best way to get from Buffalo to Lisle without a car is to train which takes 13h 8m and costs $85 - $280.
It takes approximately 5h 37m to get from Buffalo to Lisle, including transfers.
Buffalo to Lisle bus services, operated by Greyhound USA, depart from Buffalo station.
Buffalo to Lisle train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from Buffalo to Lisle is to train which takes 13h 8m and costs $85 - $280. Alternatively, you can bus, which costs $65 - $150 and takes 15h 8m.
What companies run services between Buffalo, NY, USA and Lisle, IL, USA?
Amtrak operates a train from Buffalo Depew Station to Chicago Union Station twice daily. Tickets cost $75–200 and the journey takes 10h 33m. Alternatively, you can take a bus from Buffalo to Ogden Ave & Main St via Cleveland Bus Station, Chicago Bus Station, Harrison & Jefferson, Cicero & 24th Place Terminal, Cicero & 24th Place, 54th Ave CTA Station/Pink Line, and Yorktown Center in around 15h 8m.
- Website
- united.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 6m
- When
- Every day
- Estimated price
- $75–460
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $100–550
Flights from Rochester to Chicago O'Hare International Airport
- Ave. Duration
- 2h 27m
- When
- Every day
- Estimated price
- $60–370
Flights from Rochester to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $80–440
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $75–460
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport via Detroit
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $100–700
Flights from Rochester to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $60–370
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- $75–460
Flights from Rochester to Chicago O'Hare International Airport
- Ave. Duration
- 2h 24m
- When
- Every day
- Estimated price
- $60–370
Flights from Rochester to Chicago O'Hare International Airport via Philadelphia
- Ave. Duration
- 5h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $85–450
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport
- Ave. Duration
- 2h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–700
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport via Baltimore
- Ave. Duration
- 4h 22m
- When
- Monday and Sunday
- Estimated price
- $150–850
- Phone
- +1 312-322-6777
- Website
- metra.com
Train from Chicago Union Station to Lisle
- Ave. Duration
- 56 min
- Frequency
- Hourly
- Estimated price
- $4–6
- Website
- https://metra.com
- Adult
- $4–6
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo Depew Station to Chicago Union Station
- Ave. Duration
- 10h 33m
- Frequency
- Twice daily
- Estimated price
- $75–200
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Buffalo to Cleveland Bus Station
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Estimated price
- $26–55
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Chicago Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- Twice daily
- Estimated price
- $40–80
- Website
- https://www.greyhound.com/
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Cleveland Bus Station to Chicago Bus Station
- Ave. Duration
- 7h 35m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- https://baronsbus.com
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Buffalo, NY to Rochester, NY
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $20–55
- Website
- https://www.ourbus.com
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More Questions & Answers
Buffalo to Lisle bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Lisle is 1h behind Buffalo. It is currently 6:18 AM in Buffalo and 5:18 AM in Lisle.
Buffalo to Lisle train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Buffalo to Lisle is 553 miles. It takes approximately 9h 31m to drive from Buffalo to Lisle.
There are 246+ hotels available in Lisle.