There are 5 ways to get from Buffalo to Lexington by plane, subway, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly, subway, line 62 bus  •  3 h 59 min

  1. Fly from Buffalo (BUF) to Boston (BOS) BUF - BOS
  2. Take the subway from South Station - Inbound to Alewife
  3. Take the line 62 bus from Alewife Station Busway to Massachusetts Ave @ Lexington Post Office

$90 - $361

Cheapest option

Bus Greyhound USA  •  12 h 47 min

  1. Take the bus from Buffalo, Ny to Boston, Ma 255 / ...

$56 - $132

3 alternative options

Bus Trailways New York  •  13 h 2 min

  1. Take the bus from Buffalo, NY to Albany, NY
  2. Take the bus from Albany, NY to Boston, MA South Station Albany

$71 - $130

Train  •  13 h 35 min

  1. Take the train from Buffalo Depew Station Amtrak to Boston South Station Amtrak Lake Shore Limited

$99 - $269

Drive  •  7 h 47 min

  1. Drive from Buffalo to Lexington 455 miles

$40 - $65

What companies run services between Buffalo, NY, USA and Lexington, MA, USA?

Greyhound USA operates a bus from Buffalo to Lexington every 30 minutes. Tickets cost $50 - $130 and the journey takes 11 h 40 min. Alternatively, Amtrak operates a train from Buffalo to Lexington once daily. Tickets cost $75 - $210 and the journey takes 11 h 10 min.

Airlines
JetBlue Airways
Website
jetblue.com
Flights from Buffalo to Boston
Ave. Duration
1 h 19 min
When
Every day
Estimated price
$100 - $550
Delta
Website
delta.com
Flights from Buffalo to Boston
Ave. Duration
1 h 26 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$130 - $750
Southwest Airlines
Website
southwest.com
Flights from Buffalo to Boston via Baltimore
Ave. Duration
3 h 22 min
When
Saturday and Sunday
Estimated price
$220 - $800
Train operators
MBTA
Website
mbta.com
Subway from South Station - Inbound to Alewife
Ave. Duration
22 min
Frequency
Every 10 minutes
Estimated price
$3
Schedules at
mbta.com
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Buffalo Depew Station Amtrak to Boston South Station Amtrak
Ave. Duration
11 h 10 min
Frequency
Once daily
Estimated price
$75 - $210
Website
amtrak.com
Coach Seat
$75 - $110
Flexi Coach Seat
$130 - $190
Business Coach Seat
$140 - $210
Room
$320 - $440
Bus operators
MBTA
Website
mbta.com
Bus from Alewife Station Busway to Massachusetts Ave @ Lexington Post Office
Ave. Duration
21 min
Frequency
Hourly
Estimated price
$2 - $6
Schedules at
mbta.com
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Buffalo, Ny to Boston, Ma
Ave. Duration
11 h 40 min
Frequency
Every 30 minutes
Estimated price
$50 - $130
Website
greyhound.com
Economy
$50 - $80
Flexible
$95 - $130
Trailways New York
Website
trailwaysny.com
Bus from Buffalo, NY to Albany, NY
Ave. Duration
6 h 15 min
Frequency
4 times a day
Estimated price
$45 - $70
Schedules at
trailwaysny.com
Book at
trailwaysny.com
Peter Pan Bus Lines
Phone
1-800-343-9999
Email
dveronesi@peterpanbus.com
Website
peterpanbus.com
Bus from Albany, NY to Boston, MA South Station
Ave. Duration
4 h 40 min
Frequency
Twice daily
Estimated price
$20 - $55
Website
peterpanbus.com

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Questions & Answers

How far is it from Buffalo to Lexington?

The distance between Buffalo and Lexington is 627 km. The road distance is 728 km.

What is the cheapest way to get from Buffalo to Lexington?

The cheapest way to get from Buffalo to Lexington is to drive which costs $40 - $65 and takes 7 h 47 min.

What is the fastest way to get from Buffalo to Lexington?

The quickest way to get from Buffalo to Lexington is to fly and subway and line 62 bus which takes 3 h 59 min and costs $90 - $370.

How long does it take to get from Buffalo to Lexington?

It takes approximately 3 h 59 min to get from Buffalo to Lexington, including transfers.