There are 5 ways to get from Buffalo to Lexington by plane, subway, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from Buffalo, subway, line 62 bus  •  4 h 3 min

  1. Fly from Buffalo (BUF) to Boston (BOS) BUF - BOS
  2. Take the subway from South Station to Alewife
  3. Take the line 62 bus from Alewife to Massachusetts Ave @ Lexington Post Office

$84 - $361

Cheapest option

Bus  •  12 h 46 min

  1. Take the bus from Buffalo, Ny to Boston, Ma 255 / ...

$56 - $132

3 alternative options

Train to Rochester, fly, subway, line 62 bus  •  5 h 59 min

  1. Take the train from Buffalo to Rochester
  2. Fly from Rochester (ROC) to Boston (BOS) ROC - BOS
  3. Take the subway from South Station to Alewife
  4. Take the line 62 bus from Alewife to Massachusetts Ave @ Lexington Post Office

$153 - $526

Train  •  13 h 30 min

  1. Take the train from Buffalo Depew Station Amtrak to Boston South Station Lake Shore Limited

$99 - $268

Drive  •  7 h 47 min

  1. Drive from Buffalo to Lexington 455 miles

$40 - $65

Questions & Answers

The distance between Buffalo and Lexington is 392 miles. The road distance is 455 miles.

Get driving directions

The best way to get from Buffalo to Lexington without a car is to bus which takes 12 h 46 min and costs .

More details

It takes approximately 4 h 3 min to get from Buffalo to Lexington, including transfers.

More details

The best way to get from Buffalo to Lexington is to bus which takes 12 h 46 min and costs . Alternatively, you can train, which costs and takes 13 h 30 min.

Mode details

The quickest flight from Buffalo Airport to Boston Airport is the direct flight which takes 1 h 18 min.

Search flights

Yes, the driving distance between Buffalo to Lexington is 455 miles. It takes approximately 7 h 47 min to drive from Buffalo to Lexington.

Get driving directions

Southwest Airlines, Delta, United Airlines and JetBlue Airways offer flights from Buffalo Airport to Boston Airport.

Search flights

There are 738+ hotels available in Lexington. Prices start at $135 USD per night.

More details

The best way to get from Buffalo to Buffalo Airport is to bus which takes 15 min and costs .

More details

Map of how to get from Buffalo to Lexington.
Launch map view
  • Distance: 392.2 miles
  • Duration: 4 h 3 min

What companies run services between Buffalo, NY, USA and Lexington, MA, USA?

Greyhound USA operates a bus from Buffalo to Lexington every 30 minutes. Tickets cost $50 - $130 and the journey takes 11 h 40 min. Alternatively, Amtrak operates a train from Buffalo to Lexington once daily. Tickets cost $75 - $210 and the journey takes 11 h 10 min.

Airlines
JetBlue Airways
Website
jetblue.com
Flights from Buffalo to Boston
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$100 - $550
Delta
Website
delta.com
Flights from Buffalo to Boston
Ave. Duration
1 h 32 min
When
Every day
Estimated price
$130 - $750
United Airlines
Website
united.com
Flights from Buffalo to Boston via Newark
Ave. Duration
3 h 30 min
When
Every day
Estimated price
$170 - $900
Flights from Rochester to Boston via Newark
Ave. Duration
3 h 16 min
When
Every day
Estimated price
$180 - $850
Southwest Airlines
Website
southwest.com
Flights from Buffalo to Boston via Baltimore
Ave. Duration
3 h 30 min
When
Saturday
Estimated price
$220 - $800
Flights from Rochester to Boston via Baltimore
Ave. Duration
3 h 35 min
When
Monday to Saturday
Estimated price
$250 - $750
American Airlines
Website
aa.com
Flights from Rochester to Boston
Ave. Duration
1 h 21 min
When
Every day
Estimated price
$150 - $700
Air Canada
Website
aircanada.com
Flights from Rochester to Boston via Toronto
Ave. Duration
3 h 32 min
When
Every day
Estimated price
$140 - $600
Train operators
MBTA
Phone
617-222-3200
Website
mbta.com
Subway from South Station to Alewife
Ave. Duration
21 min
Frequency
Every 10 minutes
Estimated price
$3
Schedules at
mbta.com
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Buffalo to Rochester
Ave. Duration
1 h 8 min
Frequency
Every 3 hours
Estimated price
$25 - $75
Website
viarail.ca
Escape
$25 - $35
Economy
$30 - $45
Economy Plus
$50 - $75
Business
$45 - $65
Business Plus/Sleeper
$80 - $120
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Buffalo Exchange Street Amtrak to Rochester Amtrak
Ave. Duration
1 h 8 min
Frequency
3 times a day
Estimated price
$26 - $55
Website
amtrak.com
Coach Seat
$26 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$35 - $55
Room
$140 - $210
Train from Buffalo Depew Station Amtrak to Boston South Station
Ave. Duration
11 h 10 min
Frequency
Once daily
Estimated price
$75 - $210
Website
amtrak.com
Coach Seat
$75 - $110
Flexi Coach Seat
$130 - $190
Business Coach Seat
$140 - $210
Room
$320 - $440
Bus operators
MBTA
Phone
617-222-3200
Website
mbta.com
Bus from Alewife to Massachusetts Ave @ Lexington Post Office
Ave. Duration
21 min
Frequency
Hourly
Estimated price
$2 - $6
Website
MBTA
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Buffalo, Ny to Boston, Ma
Ave. Duration
11 h 40 min
Frequency
Every 30 minutes
Estimated price
$50 - $130
Website
greyhound.com
Economy
$50 - $80
Flexible
$95 - $130

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