There are 4 ways to get from Buffalo to Lexington by plane, subway, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly, subway, line 62 bus  •  4 h 5 min

  1. Fly from Buffalo (BUF) to Boston (BOS) BUF - BOS
  2. Take the subway from South Station to Alewife
  3. Take the line 62 bus from Alewife to Massachusetts Ave @ Lexington Post Office

$90 - $361

Cheapest option

Bus  •  12 h 49 min

  1. Take the bus from Buffalo, Ny to Boston, Ma 255 / ...

$56 - $132

2 alternative options

Train  •  13 h 33 min

  1. Take the train from Buffalo Depew Station Amtrak to Boston South Station Amtrak Lake Shore Limited

$99 - $267

Drive  •  7 h 47 min

  1. Drive from Buffalo to Lexington 455 miles

$40 - $65

Questions & Answers

The cheapest way to get from Buffalo to Lexington is to drive which costs $40 - $65 and takes 7 h 47 min.

More details

The quickest way to get from Buffalo to Lexington is to fly and subway and line 62 bus which costs $90 - $370 and takes 4 h 5 min.

More details

The distance between Buffalo and Lexington is 392 miles. The road distance is 455 miles.

Get driving directions

It takes approximately 4 h 5 min to get from Buffalo to Lexington, including transfers.

More details

What companies run services between Buffalo, NY, USA and Lexington, MA, USA?

Greyhound USA operates a bus from Buffalo to Lexington every 30 minutes. Tickets cost $50 - $130 and the journey takes 11 h 40 min. Alternatively, Amtrak operates a train from Buffalo to Lexington once daily. Tickets cost $75 - $210 and the journey takes 11 h 10 min.

Airlines
JetBlue Airways
Website
jetblue.com
Flights from Buffalo to Boston
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$100 - $550
Delta
Website
delta.com
Flights from Buffalo to Boston
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$130 - $750
United Airlines
Website
united.com
Flights from Buffalo to Boston via Newark
Ave. Duration
3 h 23 min
When
Every day
Estimated price
$170 - $900
Flights from Buffalo to Boston via Washington Dulles
Ave. Duration
3 h 38 min
When
Saturday and Sunday
Estimated price
$170 - $900
Southwest Airlines
Website
southwest.com
Flights from Buffalo to Boston via Baltimore
Ave. Duration
3 h 35 min
When
Monday to Friday
Estimated price
$220 - $800
Train operators
MBTA
Website
mbta.com
Subway from South Station to Alewife
Ave. Duration
22 min
Frequency
Every 10 minutes
Estimated price
$3
Schedules at
mbta.com
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Buffalo Depew Station Amtrak to Boston South Station Amtrak
Ave. Duration
11 h 10 min
Frequency
Once daily
Estimated price
$75 - $210
Website
amtrak.com
Coach Seat
$75 - $110
Flexi Coach Seat
$130 - $190
Business Coach Seat
$140 - $210
Room
$320 - $440
Bus operators
MBTA
Website
mbta.com
Bus from Alewife to Massachusetts Ave @ Lexington Post Office
Ave. Duration
20 min
Frequency
Hourly
Estimated price
$2 - $6
Schedules at
mbta.com
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Buffalo, Ny to Boston, Ma
Ave. Duration
11 h 40 min
Frequency
Every 30 minutes
Estimated price
$50 - $130
Website
greyhound.com
Economy
$50 - $80
Flexible
$95 - $130

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