Rome2Rio

How to get fromBuffalo to Lewis Centerby bus (Flixbus), train, bus, car, or plane

Find Transport to Lewis Center

See all options

There are 7 ways to get from Buffalo to Lewis Center by bus (Flixbus), train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Flixbus)

    best
    1. Take the bus from Buffalo to Columbusbus bus FlixBus 2526
    8h 48m
    $54–79

  2. Bus via Mt. Carmel @ Fitness & Health Center

    cheapest
    1. Take the bus from Buffalo to Columbusbus bus Bsb 11 / ...
    9h 38m
    $39–85

  3. Train, bus

    1. Take the train from Buffalo Depew Station to Cleveland Amtraktrain train Lake Shore Limited
    2. Take the bus from Cleveland Bus Station to Columbusbus bus Greyhound US0105
    9h 29m
    $115–340

  4. Drive  311 mi

    1. Drive from Buffalo to Lewis Centercar car 311 mi
    5h 23m
    $57–82

  5. Fly from Buffalo Niagara International Airport

    1. Fly from Buffalo Niagara International Airport (BUF) to John Glenn Columbus International Airport (CMH)plane plane BUF - CMH
    5h 25m
    $127–562

  6. Bus to Rochester, fly

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to John Glenn Columbus International Airport (CMH)plane plane ROC - CMH
    6h 41m
    $174–752

  7. Bus to Toronto Pearson International Airport, fly

    1. Take the bus from Buffalo to Mississaugabus bus
    2. Fly from Toronto Pearson International Airport (YYZ) to John Glenn Columbus International Airport (CMH)plane plane YYZ - CMH
    7h
    $460–1,419

Buffalo Niagara International Airport (BUF) to John Glenn Columbus International Airport (CMH) flights

Calendar131Weekly Planes
Duration4h 33mAverage Duration
Ticket$81Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Buffalo to Lewis Center.ExpandLaunch map view
  • Distance: 352.5 mi
  • Duration: 8h 48m

What companies run services between Buffalo, NY, USA and Lewis Center, OH, USA?

Flixbus USA operates a bus from Buffalo to Columbus 6 times a week. Tickets cost $50–75 and the journey takes 6h 25m. Alternatively, Delta, United Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to John Glenn Columbus International Airport (CMH) hourly.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There