Rome2Rio

How to get fromBuffalo to Knoxby train, car, bus (Greyhound), plane or taxi

Find Transport to Knox

See all options

There are 6 ways to get from Buffalo to Knox by train, car, bus (Greyhound), plane, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, drive (Amtrak)

    best
    1. Take the train from Buffalo Depew Station to Elkhart Amtrak Stationtrain train Lake Shore Limited
    2. Drive from Elkhart Amtrak Station to Knoxcar car
    10h 43m
    $139–359
  2. Drive 475.5 mi

    cheapest
    1. Drive from Buffalo to Knoxcar car 475.5 mi
    8h 43m
    $87–126
  3. Bus

    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus Greyhound US0170
    2. Take the bus from Cleveland Bus Station to South Bend Transpobus bus Greyhound US0164
    12h 22m
    $142–246
  4. Fly to South Bend, taxi

    1. Fly from Buffalo Niagara International Airport (BUF) to South Bend (SBN)plane plane BUF - SBN
    2. Take the taxi from South-Bend-Airport-SBN to Knoxtaxi taxi
    6h 44m
    $242–952
  5. Fly to Chicago Midway International Airport, train, taxi

    1. Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane plane BUF - MDW
    2. Take the train from Museum Campus/11th St. to Beverly Shorestrain train
    3. Take the taxi from Beverly Shores to Knoxtaxi taxi
    6h 55m
    $243–928
  6. Fly to Chicago O'Hare International Airport, train, taxi

    1. Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane plane BUF - ORD
    2. Take the train from Van Buren St. to Beverly Shorestrain train
    3. Take the taxi from Beverly Shores to Knoxtaxi taxi
    7h 18m
    $203–608

Buffalo Niagara International Airport (BUF) to South Bend (SBN) flights

Calendar55Weekly Planes
Duration5h 27mAverage Duration
Ticket$125Cheapest Price
See schedules

Questions & Answers

What companies run services between Buffalo, NY, USA and Knox, Starke County, IN, USA?

You can take a bus from Buffalo to Knox via Cleveland Bus Station, South Bend Transpo, South Street Station - South Bend, and Plymouth - Pilot Travel Center in around 12h 22m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound