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How to get fromBuffalo to Key Westby plane, train, bus, bus (Greyhound), car or shuttle

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There are 7 ways to get from Buffalo to Key West by plane, train, bus, bus (Greyhound), car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Key West International Airport (EYW)planeBUF - EYW
    6h 39m
    $215–1,043

  2. Fly from Niagara Falls International Airport

    cheapest
    1. Fly from Niagara Falls International Airport (IAG) to Key West International Airport (EYW)planeIAG - EYW
    22h 11m
    $135–617

  3. Train, bus

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Stationtrain
    3. Take the bus from Miami Airport Station to Big Pine Keybus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetbusLks
    44h 56m
    $283–978

  4. Bus

    1. Take the bus from Buffalo to Cleveland Bus Stationbus
    2. Take the bus from Cleveland Bus Station to Atlanta Bus Stationbus
    3. Take the bus from Atlanta Bus Station to Miami Airport Stationbus
    4. Take the bus from Miami Airport Station to Big Pine Keybus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetbusLks
    46h 46m
    $227–576

  5. Drive 1,536.5 mi

    1. Drive from Buffalo to Key Westcar1,536.5 mi
    26h 17m
    $281–405

  6. Bus to Rochester, fly

    1. Take the bus from Buffalo, NY to Rochester, NYbus
    2. Fly from Rochester (ROC) to Key West International Airport (EYW)planeROC - EYW
    9h 28m
    $205–948

  7. Bus, train, shuttle

    1. Take the bus from Buffalo to Pittsburghbus
    2. Take the train from Pittsburgh Amtrak Station to Miami Amtrak Stationtrain
    3. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle
    2d 3h
    $383–962

Buffalo to Key West by train, taxi, bus, and foot

Calendar7Weekly Services
Duration44h 56mAverage Duration
Ticket$283Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Key West, FL, USA?

Delta, American Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Key West International Airport (EYW) 5 times a day. Alternatively, you can take a bus from Buffalo to N Roosevelt & 3rd Street via Cleveland Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 46h 46m.

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