There are 7 ways to get from Buffalo to Key West by plane, train, bus, bus (Greyhound), car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Buffalo Niagara International Airport
best- Fly from Buffalo Niagara International Airport (BUF) to Key West International Airport (EYW)BUF - EYW
6h 39m$215–1,043Fly from Niagara Falls International Airport
cheapest- Fly from Niagara Falls International Airport (IAG) to Key West International Airport (EYW)IAG - EYW
22h 11m$135–617Train, bus
- Take the train from Buffalo to Ny Moynihan Train Hall At Penn Station
- Take the train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Station
- Take the bus from Miami Airport Station to Big Pine Key
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetLks
44h 56m$283–978Bus
- Take the bus from Buffalo to Cleveland Bus Station
- Take the bus from Cleveland Bus Station to Atlanta Bus Station
- Take the bus from Atlanta Bus Station to Miami Airport Station
- Take the bus from Miami Airport Station to Big Pine Key
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetLks
46h 46m$227–576Drive 1,536.5 mi
- Drive from Buffalo to Key West1,536.5 mi
26h 17m$281–405Bus to Rochester, fly
- Take the bus from Buffalo, NY to Rochester, NY
- Fly from Rochester (ROC) to Key West International Airport (EYW)ROC - EYW
9h 28m$205–948Bus, train, shuttle
- Take the bus from Buffalo to Pittsburgh
- Take the train from Pittsburgh Amtrak Station to Miami Amtrak Station
- Take a shuttle bus from Miami, FL - International Airport to Key West, FL
2d 3h$383–962
Buffalo to Key West by train, taxi, bus, and foot
Questions & Answers
The cheapest way to get from Buffalo to Key West is to fly which costs $130 - $650 and takes 22h 11m.
The fastest way to get from Buffalo to Key West is to fly which takes 6h 39m and costs $210 - $1,100.
No, there is no direct bus from Buffalo to Key West. However, there are services departing from Buffalo and arriving at N Roosevelt & 3rd Street via Cleveland Bus Station, Atlanta Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 46h 46m.
The distance between Buffalo and Key West is 1302 miles. The road distance is 1545.5 miles.
The best way to get from Buffalo to Key West without a car is to train and bus which takes 44h 56m and costs $280 - $1,000.
It takes approximately 6h 39m to get from Buffalo to Key West, including transfers.
Buffalo to Key West bus services, operated by Greyhound USA, depart from Buffalo station.
The best way to get from Buffalo to Key West is to fly which takes 6h 39m and costs $210 - $1,100. Alternatively, you can bus, which costs $220 - $600 and takes 46h 46m.
Buffalo to Key West bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Yes, the driving distance between Buffalo to Key West is 1545 miles. It takes approximately 26h 17m to drive from Buffalo to Key West.
What companies run services between Buffalo, NY, USA and Key West, FL, USA?
Delta, American Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Key West International Airport (EYW) 5 times a day. Alternatively, you can take a bus from Buffalo to N Roosevelt & 3rd Street via Cleveland Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 46h 46m.
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 7h 37m
- When
- Every day
- Estimated price
- $200–950
Flights from Buffalo Niagara International Airport to Key West International Airport via Miami
- Ave. Duration
- 6h 27m
- When
- Saturday
- Estimated price
- $200–950
Flights from Buffalo Niagara International Airport to Key West International Airport via Reagan Washington
- Ave. Duration
- 10h 9m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $200–950
Flights from Rochester to Key West International Airport via Charlotte
- Ave. Duration
- 8h 30m
- When
- Every day
- Estimated price
- $170–800
Flights from Rochester to Key West International Airport via Miami
- Ave. Duration
- 6h 26m
- When
- Saturday
- Estimated price
- $170–800
Flights from Rochester to Key West International Airport via Reagan Washington
- Ave. Duration
- 9h 17m
- When
- Sunday
- Estimated price
- $170–800
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $210–950
Flights from Rochester to Key West International Airport via Atlanta
- Ave. Duration
- 7h 4m
- When
- Every day
- Estimated price
- $170–800
- Website
- allegiantair.com
Flights from Niagara Falls International Airport to Key West International Airport via St. Petersburg
- Ave. Duration
- 23h 48m
- When
- Tuesday, Friday, and Sunday
- Estimated price
- $120–600
Flights from Niagara Falls International Airport to Key West International Airport via Orlando Sanford
- Ave. Duration
- 20h 10m
- When
- Friday
- Estimated price
- $120–600
- Website
- flybreeze.com
Flights from Buffalo Niagara International Airport to Key West International Airport via Tampa
- Ave. Duration
- 5h 19m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- $200–950
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 8h 27m
- Frequency
- 3 times a day
- Estimated price
- $75–160
- Website
- https://www.amtrak.com/home.html
Train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Station
- Ave. Duration
- 28h 29m
- Frequency
- Once daily
- Estimated price
- $160–750
- Website
- https://www.amtrak.com/home.html
Train from Pittsburgh Amtrak Station to Miami Amtrak Station
- Ave. Duration
- 36h 49m
- Frequency
- Once daily
- Estimated price
- $160–550
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $22–40
- Website
- https://www.greyhound.com/
Bus from Buffalo to Cleveland Bus Station
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Estimated price
- $27–65
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Atlanta Bus Station
- Ave. Duration
- 20h 10m
- Frequency
- Once daily
- Estimated price
- $110–270
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 14h 5m
- Frequency
- Once daily
- Estimated price
- $65–200
- Website
- https://www.greyhound.com/
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Buffalo, NY to Rochester, NY
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $20–55
- Website
- https://www.ourbus.com
- Phone
- +1 814-574-1827
- Website
- fullingtontours.com
Bus from Buffalo to Pittsburgh
- Ave. Duration
- 7h 30m
- Frequency
- Once daily
- Estimated price
- $110–160
- Website
- https://www.fullingtontours.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Buffalo to Pittsburgh
- Ave. Duration
- 7h 30m
- Frequency
- Once daily
- Estimated price
- $40–180
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $40–170
- Flexible
- $80–180
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Key West, FL
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $150–200
- Website
- https://www.keysshuttle.com
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