There are 7 ways to get from Buffalo to Key West by plane, train, bus, bus (Greyhound, Flixbus), car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Buffalo Niagara International Airport
best- Fly from Buffalo Niagara International Airport (BUF) to Key West International Airport (EYW)plane BUF - EYW
6h 11m$157–741Fly from Niagara Falls International Airport
cheapest- Fly from Niagara Falls International Airport (IAG) to Key West International Airport (EYW)plane IAG - EYW
19h 30m$100–417Train, bus
- Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
44h 51m$568–1,240Bus
- Take the bus from Buffalo to Cleveland Bus Stationbus
- Take the bus from Cleveland Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
46h 11m$262–553Drive 1,536.5 mi
- Drive from Buffalo to Key Westcar 1,536.5 mi
26h 33m$281–405Bus to Rochester, fly
- Take the bus from Buffalo to Rochester Bus Stopbus
- Fly from Rochester (ROC) to Key West International Airport (EYW)plane ROC - EYW
7h 57m$149–558Bus, train, shuttle
- Take the bus from Buffalo to Pittsburghbus
- Take the train from Pittsburgh Amtrak Station to Miami Amtrak Stationtrain
- Take a shuttle bus from Miami, FL - International Airport to Key West, FL
2d 3h$700–1,408
Buffalo to Key West by train, taxi, bus, and foot
Questions & Answers
The cheapest way to get from Buffalo to Key West is to fly which costs $100 - $420 and takes 19h 30m.
The fastest way to get from Buffalo to Key West is to fly which takes 6h 11m and costs $150 - $750.
No, there is no direct bus from Buffalo to Key West. However, there are services departing from Buffalo and arriving at N Roosevelt & 3rd Street via Cleveland Bus Station, Atlanta Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 46h 11m.
The distance between Buffalo and Key West is 1302 miles. The road distance is 1545.5 miles.
The best way to get from Buffalo to Key West without a car is to train and bus which takes 44h 51m and costs $550 - $1,300.
It takes approximately 6h 11m to get from Buffalo to Key West, including transfers.
Buffalo to Key West bus services, operated by Greyhound USA, depart from Buffalo station.
The best way to get from Buffalo to Key West is to fly which takes 6h 11m and costs $150 - $750. Alternatively, you can bus, which costs $260 - $600 and takes 46h 11m.
Buffalo to Key West bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Yes, the driving distance between Buffalo to Key West is 1545 miles. It takes approximately 26h 33m to drive from Buffalo to Key West.
What companies run services between Buffalo, NY, USA and Key West, FL, USA?
Delta, American Airlines, and Frontier Airlines fly from Buffalo Niagara International Airport (BUF) to Key West International Airport (EYW) 4 times a day. Alternatively, you can take a bus from Buffalo to N Roosevelt & 3rd Street via Cleveland Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 46h 11m.
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $150–700
Flights from Rochester to Key West International Airport via Atlanta
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $110–550
Flights from Niagara Falls International Airport to Key West International Airport via Myrtle Beach, Atlanta
- Ave. Duration
- 17h 24m
- When
- Monday and Friday
- Estimated price
- $100–450
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Key West International Airport via Miami
- Ave. Duration
- 5h 40m
- When
- Saturday
- Estimated price
- $150–700
Flights from Buffalo Niagara International Airport to Key West International Airport via Reagan Washington
- Ave. Duration
- 6h 4m
- When
- Saturday
- Estimated price
- $150–700
Flights from Buffalo Niagara International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $140–700
Flights from Rochester to Key West International Airport via Miami
- Ave. Duration
- 6h 9m
- When
- Saturday
- Estimated price
- $110–500
Flights from Rochester to Key West International Airport via Reagan Washington
- Ave. Duration
- 6h 20m
- When
- Every day
- Estimated price
- $110–500
Flights from Rochester to Key West International Airport via Charlotte
- Ave. Duration
- 7h 1m
- When
- Every day
- Estimated price
- $110–500
- Website
- united.com
Flights from Rochester to Key West International Airport via Newark
- Ave. Duration
- 7h 30m
- When
- Every day
- Estimated price
- $120–550
- Website
- allegiantair.com
Flights from Niagara Falls International Airport to Key West International Airport via St. Petersburg
- Ave. Duration
- 20h 44m
- When
- Thursday and Sunday
- Estimated price
- $85–400
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 8h 17m
- Frequency
- 3 times a day
- Estimated price
- $120–280
- Website
- https://www.amtrak.com/home.html
Train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Station
- Ave. Duration
- 28h 29m
- Frequency
- Once daily
- Estimated price
- $400–900
- Website
- https://www.amtrak.com/home.html
Train from Pittsburgh Amtrak Station to Miami Amtrak Station
- Ave. Duration
- 36h 44m
- Frequency
- Once daily
- Estimated price
- $460–1,000
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $19–40
- Website
- https://www.greyhound.com/
Bus from Buffalo to Cleveland Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $30–60
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Atlanta Bus Station
- Ave. Duration
- 20h 30m
- Frequency
- Once daily
- Estimated price
- $120–240
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 17h 20m
- Frequency
- Once daily
- Estimated price
- $100–210
- Website
- https://www.greyhound.com/
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $11–23
- Website
- https://www.greyhound.com/
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 13h 30m
- Frequency
- Once daily
- Estimated price
- $90–150
- Schedules at
- flixbus.com
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- Every 3 hours
- Estimated price
- $9–17
- Schedules at
- flixbus.com
- Phone
- +1 814-574-1827
- Website
- fullingtontours.com
Bus from Buffalo to Pittsburgh
- Ave. Duration
- 7h 30m
- Frequency
- Once daily
- Estimated price
- $90–190
- Website
- https://www.fullingtontours.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Buffalo to Pittsburgh
- Ave. Duration
- 7h 30m
- Frequency
- Once daily
- Estimated price
- $40–180
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $40–170
- Flexible
- $80–180
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Key West, FL
- Ave. Duration
- 4h
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- https://www.keysshuttle.com
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