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How to get fromBuffalo to Key Westby plane, train, bus, bus (Greyhound, Flixbus), car or shuttle

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There are 6 ways to get from Buffalo to Key West by plane, train, bus, bus (Greyhound, Flixbus), car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Key West International Airport (EYW)plane plane BUF - EYW
    6h 45m
    $235–1,193
  2. Bus

    cheapest
    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    2d 2h
    $186–529
  3. Train, bus

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    44h 56m
    $263–925
  4. Drive 1,536.5 mi

    1. Drive from Buffalo to Key Westcar car 1,536.5 mi
    26h 32m
    $281–405
  5. Bus to Rochester, fly

    1. Take the bus from Buffalo, NY to Rochester, NYbus bus
    2. Fly from Rochester (ROC) to Key West International Airport (EYW)plane plane ROC - EYW
    8h 50m
    $215–998
  6. Bus, train, shuttle

    1. Take the bus from Buffalo to Pittsburghbus bus
    2. Take the train from Pittsburgh Amtrak Station to Miami Amtrak Stationtrain train
    3. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus
    2d 3h
    $383–892

Buffalo to Key West by train, taxi, bus, and foot

Calendar7Weekly Services
Duration44h 56mAverage Duration
Ticket$263Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Key West, FL, USA?

Delta, American Airlines, and three other airlines fly from Buffalo Niagara International Airport (BUF) to Key West International Airport (EYW) 5 times a day. Alternatively, you can take a bus from Buffalo to N Roosevelt & 3rd Street via Cleveland Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 2d 2h.

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