There are 7 ways to get from Buffalo to Key Largo by plane, shuttle, bus (Flixbus, Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Buffalo Niagara International Airport to Miami International Airport, shuttle
best- Fly from Buffalo Niagara International Airport (BUF) to Miami International Airport (MIA)plane BUF - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
7h 1m$202–682Bus
- Take the bus from Buffalo to New York Midtownbus
- Take the bus from New York Midtown to Washington Union Stationbus
- Take the bus from Washington Union Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
38h 40m$285–437Train, bus
- Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
40h 35m$1,006–1,594Drive 1,439.3 mi
- Drive from Buffalo to Key Largocar 1,439.3 mi
24h 16m$263–380Fly Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Buffalo Niagara International Airport (BUF) to Fort Lauderdale–Hollywood International Airport (FLL)plane BUF - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
7h 18m$232–702Bus to Rochester, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Take the bus from Buffalo to Rochester Bus Stopbus
- Fly from Rochester (ROC) to Fort Lauderdale–Hollywood International Airport (FLL)plane ROC - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
8h 19m$310–992Bus, train
- Take the bus from Buffalo, Ny to Pittsburgh, Pabus 530
- Take the train from Pittsburgh Amtrak Station to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
2d$914–1,634
Buffalo to Key Largo by bus
Comparing Your Travel Options
The cheapest way to get from Buffalo to Key Largo is to drive which costs $260 - $380 and takes 24h 16m.
The fastest way to get from Buffalo to Key Largo is to fly and shuttle which takes 7h 1m and costs $200 - $700.
No, there is no direct bus from Buffalo to Key Largo. However, there are services departing from Buffalo and arriving at Key Largo Bus Stop via New York Midtown, Washington Union Station and Miami Airport Station. The journey, including transfers, takes approximately 38h 40m.
The distance between Buffalo and Key Largo is 1264 miles. The road distance is 1447.7 miles.
The best way to get from Buffalo to Key Largo without a car is to bus which takes 38h 40m and costs $280 - $440.
It takes approximately 7h 1m to get from Buffalo to Key Largo, including transfers.
Buffalo to Key Largo bus services, operated by Flixbus USA, depart from Buffalo station.
Buffalo to Key Largo bus services, operated by Flixbus USA, arrive at New York Midtown station.
Yes, the driving distance between Buffalo to Key Largo is 1448 miles. It takes approximately 24h 16m to drive from Buffalo to Key Largo.
Book your Buffalo to Key Largo bus tickets online with Omio and FlixBus.
What companies run services between Buffalo, NY, USA and Key Largo, FL, USA?
You can take a bus from Buffalo to Key Largo Bus Stop via New York Midtown, Washington Union Station, and Miami Airport Station in around 38h 40m.
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Miami International Airport
- Ave. Duration
- 3h 15m
- When
- Saturday
- Estimated price
- $100–550
Flights from Buffalo Niagara International Airport to Miami International Airport via Orlando
- Ave. Duration
- 4h 55m
- When
- Saturday
- Estimated price
- $100–550
Flights from Buffalo Niagara International Airport to Miami International Airport via Baltimore
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $110–550
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 15m
- When
- Saturday
- Estimated price
- $110–550
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Orlando
- Ave. Duration
- 4h 45m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $110–600
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Baltimore
- Ave. Duration
- 4h 51m
- When
- Tuesday, Wednesday, Sunday, Monday, Thursday, and Friday
- Estimated price
- $110–600
Flights from Rochester to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 20m
- When
- Saturday
- Estimated price
- $160–800
Flights from Rochester to Fort Lauderdale–Hollywood International Airport via Baltimore
- Ave. Duration
- 5h 6m
- When
- Every day
- Estimated price
- $160–800
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Miami International Airport
- Ave. Duration
- 3h 19m
- When
- Saturday
- Estimated price
- $100–550
Flights from Buffalo Niagara International Airport to Miami International Airport via Charlotte
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $100–550
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Charlotte
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $110–550
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Miami International Airport via Atlanta
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $110–550
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Atlanta
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $120–600
- Website
- allegiantair.com
Flights from Rochester to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 55m
- When
- Thursday and Sunday
- Estimated price
- $160–800
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 2m
- When
- Every day
- Estimated price
- $110–550
- Website
- united.com
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Washington Dulles
- Ave. Duration
- 5h 3m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
- Website
- flybreeze.com
Flights from Rochester to Fort Lauderdale–Hollywood International Airport via Myrtle Beach
- Ave. Duration
- 6h 28m
- When
- Thursday and Sunday
- Estimated price
- $270–1,500
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Buffalo to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 8h 17m
- Frequency
- 3 times a day
- Estimated price
- $240–380
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Hollywood Amtrak Station
- Ave. Duration
- 27h 51m
- Frequency
- Once daily
- Estimated price
- $750–1,200
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Hollywood Amtrak Station
- Ave. Duration
- 36h 21m
- Frequency
- Once daily
- Estimated price
- $850–1,400
- Website
- Amtrak
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $100–130
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $120–150
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $120–150
- Website
- Keys Shuttle
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Buffalo to New York Midtown
- Ave. Duration
- 8h 25m
- Frequency
- Every 4 hours
- Estimated price
- $65–100
- Schedules at
- Flixbus USA
Bus from New York Midtown to Washington Union Station
- Ave. Duration
- 4h 30m
- Frequency
- Every 2 hours
- Estimated price
- $40–65
- Schedules at
- Flixbus USA
Bus from Washington Union Station to Miami Airport Station
- Ave. Duration
- 21h 25m
- Frequency
- 4 times a week
- Estimated price
- $170–260
- Schedules at
- Flixbus USA
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $11–18
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $10–15
- Website
- Greyhound
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $10–15
- Website
- Greyhound
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $13–20
- Website
- Greyhound
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $10–15
- Website
- Greyhound
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Buffalo, Ny to Pittsburgh, Pa
- Saver
- $50–210
- Flexible
- $90–220
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Booking & Getting There
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