There are 7 ways to get from Buffalo to Key Largo by plane, shuttle, train, bus, bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport, shuttle
best- Fly from Buffalo Niagara International Airport (BUF) to Fort Lauderdale–Hollywood International Airport (FLL)plane BUF - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
7h 10m$224–820Bus (Greyhound)
cheapest- Take the bus from Buffalo to Cleveland Bus Stationbus
- Take the bus from Cleveland Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
42h 25m$187–518Train, bus
- Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
40h 55m$281–981Drive 1,439.4 mi
- Drive from Buffalo to Key Largocar 1,439.4 mi
24h 3m$263–380Fly Buffalo Niagara International Airport to Miami International Airport, shuttle
- Fly from Buffalo Niagara International Airport (BUF) to Miami International Airport (MIA)plane BUF - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
7h 13m$244–990Shuttle to Toronto Pearson International Airport, fly to Miami International Airport, shuttle
- Take a shuttle bus from Buffalo Airport to Pearson International Airport Terminal 1
- Fly from Toronto Pearson International Airport (YYZ) to Miami International Airport (MIA)plane YYZ - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
10h 25m$314–860Bus, train
- Take the bus from Buffalo to Pittsburghbus
- Take the train from Pittsburgh Amtrak Station to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
2d$191–632
Buffalo to Key Largo by train and bus
Questions & Answers
The cheapest way to get from Buffalo to Key Largo is to drive which costs $260 - $380 and takes 24h 3m.
The fastest way to get from Buffalo to Key Largo is to fly and shuttle which takes 7h 10m and costs $220 - $850.
No, there is no direct bus from Buffalo to Key Largo. However, there are services departing from Buffalo and arriving at Key Largo Bus Stop via Cleveland Bus Station, Atlanta Bus Station and Miami Airport Station. The journey, including transfers, takes approximately 42h 25m.
The distance between Buffalo and Key Largo is 1269 miles. The road distance is 1447.8 miles.
The best way to get from Buffalo to Key Largo without a car is to train and bus which takes 40h 55m and costs $280 - $1,000.
It takes approximately 7h 10m to get from Buffalo to Key Largo, including transfers.
Buffalo to Key Largo bus services, operated by Greyhound USA, depart from Buffalo station.
Buffalo to Key Largo bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Yes, the driving distance between Buffalo to Key Largo is 1448 miles. It takes approximately 24h 3m to drive from Buffalo to Key Largo.
Book your Buffalo to Key Largo bus tickets online with Omio and FlixBus.
What companies run services between Buffalo, NY, USA and Key Largo, FL, USA?
You can take a bus from Buffalo to Key Largo Bus Stop via Cleveland Bus Station, Atlanta Bus Station, and Miami Airport Station in around 42h 25m.
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 10m
- When
- Saturday
- Estimated price
- $120–600
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Baltimore
- Ave. Duration
- 5h 5m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $120–600
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Orlando
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $120–600
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Tampa
- Ave. Duration
- 5h 30m
- When
- Monday to Friday
- Estimated price
- $120–600
Flights from Buffalo Niagara International Airport to Miami International Airport via Orlando
- Ave. Duration
- 5h 11m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $160–800
Flights from Buffalo Niagara International Airport to Miami International Airport via Baltimore
- Ave. Duration
- 5h 19m
- When
- Monday and Saturday
- Estimated price
- $160–800
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Charlotte
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $120–600
Flights from Buffalo Niagara International Airport to Miami International Airport
- Ave. Duration
- 3h 43m
- When
- Saturday
- Estimated price
- $160–800
Flights from Buffalo Niagara International Airport to Miami International Airport via Charlotte
- Ave. Duration
- 6h 15m
- When
- Every day
- Estimated price
- $160–800
Flights from Toronto Pearson International Airport to Miami International Airport
- Ave. Duration
- 3h 39m
- When
- Every day
- Estimated price
- $90–440
- Website
- aircanada.com
Flights from Toronto Pearson International Airport to Miami International Airport
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- $90–440
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 11m
- When
- Every day
- Estimated price
- $120–600
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Miami International Airport via Atlanta
- Ave. Duration
- 6h 13m
- When
- Every day
- Estimated price
- $170–850
- Website
- flyfrontier.com
Flights from Buffalo Niagara International Airport to Miami International Airport via Atlanta
- Ave. Duration
- 7h 1m
- When
- Monday
- Estimated price
- $170–850
- Website
- flyporter.com
Flights from Toronto Pearson International Airport to Miami International Airport
- Ave. Duration
- 3h 29m
- When
- Every day
- Estimated price
- $150–470
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 8h 27m
- Frequency
- 3 times a day
- Estimated price
- $70–160
- Website
- https://www.amtrak.com/home.html
Train from Ny Moynihan Train Hall At Penn Station to Hollywood Amtrak Station
- Ave. Duration
- 27h 51m
- Frequency
- Once daily
- Estimated price
- $190–800
- Website
- https://www.amtrak.com/home.html
Train from Pittsburgh Amtrak Station to Hollywood Amtrak Station
- Ave. Duration
- 36h 26m
- Frequency
- Once daily
- Estimated price
- $130–430
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $130–380
- Coach Seat short notice purchase
- $200–430
- Business - advance purchase
- $270–1,100
- Business Class
- $380–950
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $100–140
- Website
- https://www.keysshuttle.com
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $80–110
- Website
- https://www.keysshuttle.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- 3 times a day
- Estimated price
- $14–21
- Website
- https://www.greyhound.com/
Bus from Buffalo to Cleveland Bus Station
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Estimated price
- $27–60
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Atlanta Bus Station
- Ave. Duration
- 20h 10m
- Frequency
- Once daily
- Estimated price
- $80–230
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 14h 5m
- Frequency
- Once daily
- Estimated price
- $65–210
- Website
- https://www.greyhound.com/
- Phone
- 905-374-8111
- airsales@niagaraairbus.com
- Website
- niagaraairbus.com
Shuttle from Buffalo Airport to Pearson International Airport Terminal 1
- Ave. Duration
- 2h
- Frequency
- On demand
- Estimated price
- $90–120
- Website
- https://www.niagaraairbus.com
- Schedules at
- https://www.niagaraairbus.com
- Book at
- https://www.niagaraairbus.com
- Phone
- +1 814-574-1827
- Website
- fullingtontours.com
Bus from Buffalo to Pittsburgh
- Ave. Duration
- 7h 30m
- Frequency
- Once daily
- Estimated price
- $110–160
- Website
- https://www.fullingtontours.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Buffalo to Pittsburgh
- Ave. Duration
- 7h 30m
- Frequency
- Once daily
- Estimated price
- $40–180
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $40–170
- Flexible
- $80–180
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 305+ hotels available in Key Largo.













