There are 6 ways to get from Buffalo to Key Largo by plane, shuttle, train, bus, bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Miami International Airport, shuttle
best- Fly from Buffalo Niagara International Airport (BUF) to Miami International Airport (MIA)BUF - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
7h 13m$212–812Bus, train
cheapest- Take the bus from Buffalo to Pittsburgh
- Take the train from Pittsburgh Amtrak Station to Hollywood Amtrak Station
- Take the bus from Miami Airport Station to Key Largo Bus Stop
2d$190–630Train, bus
- Take the train from Buffalo to Ny Moynihan Train Hall At Penn Station
- Take the train from Ny Moynihan Train Hall At Penn Station to Hollywood Amtrak Station
- Take the bus from Miami Airport Station to Key Largo Bus Stop
40h 55m$279–828Bus (Greyhound)
- Take the bus from Buffalo to Cleveland Bus Station
- Take the bus from Cleveland Bus Station to Atlanta Bus Station
- Take the bus from Atlanta Bus Station to Miami Airport Station
- Take the bus from Miami Airport Station to Key Largo Bus Stop
42h 25m$194–393Drive 1,439.4 mi
- Drive from Buffalo to Key Largo1,439.4 mi
24h 3m$263–380Fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Buffalo Niagara International Airport (BUF) to Fort Lauderdale–Hollywood International Airport (FLL)BUF - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
7h 20m$202–642
Buffalo to Key Largo by train and bus
Questions & Answers
The cheapest way to get from Buffalo to Key Largo is to bus which costs $190 - $400 and takes 42h 25m.
The fastest way to get from Buffalo to Key Largo is to fly and shuttle which takes 7h 13m and costs $210 - $850.
No, there is no direct bus from Buffalo to Key Largo. However, there are services departing from Buffalo and arriving at Key Largo Bus Stop via Cleveland Bus Station, Atlanta Bus Station and Miami Airport Station. The journey, including transfers, takes approximately 42h 25m.
The distance between Buffalo and Key Largo is 1264 miles. The road distance is 1447.8 miles.
The best way to get from Buffalo to Key Largo without a car is to train and bus which takes 40h 55m and costs $270 - $850.
It takes approximately 7h 13m to get from Buffalo to Key Largo, including transfers.
Buffalo to Key Largo bus services, operated by Greyhound USA, depart from Buffalo station.
Buffalo to Key Largo bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Yes, the driving distance between Buffalo to Key Largo is 1448 miles. It takes approximately 24h 3m to drive from Buffalo to Key Largo.
Book your Buffalo to Key Largo bus tickets online with Omio and FlixBus.
What companies run services between Buffalo, NY, USA and Key Largo, FL, USA?
You can take a bus from Buffalo to Key Largo Bus Stop via Cleveland Bus Station, Atlanta Bus Station, and Miami Airport Station in around 42h 25m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Miami International Airport via Baltimore
- Ave. Duration
- 5h 35m
- When
- Every day
- Estimated price
- $140–700
Flights from Buffalo Niagara International Airport to Miami International Airport via Orlando
- Ave. Duration
- 5h 45m
- When
- Monday to Thursday
- Estimated price
- $140–700
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 5m
- When
- Saturday
- Estimated price
- $100–500
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Baltimore
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $100–550
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Orlando
- Ave. Duration
- 5h 20m
- When
- Thursday
- Estimated price
- $100–500
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Miami International Airport
- Ave. Duration
- 3h 27m
- When
- Saturday
- Estimated price
- $130–700
Flights from Buffalo Niagara International Airport to Miami International Airport via Charlotte
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $130–700
Flights from Buffalo Niagara International Airport to Miami International Airport via Reagan Washington
- Ave. Duration
- 5h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–700
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Charlotte
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $100–500
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Reagan Washington
- Ave. Duration
- 5h 25m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $100–550
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- $100–500
- Website
- united.com
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Washington Dulles
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $100–500
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 8h 27m
- Frequency
- 3 times a day
- Estimated price
- $80–160
- Website
- https://www.amtrak.com/home.html
Train from Ny Moynihan Train Hall At Penn Station to Hollywood Amtrak Station
- Ave. Duration
- 27h 51m
- Frequency
- Once daily
- Estimated price
- $180–650
- Website
- https://www.amtrak.com/home.html
Train from Pittsburgh Amtrak Station to Hollywood Amtrak Station
- Ave. Duration
- 36h 26m
- Frequency
- Once daily
- Estimated price
- $130–430
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $130–380
- Coach Seat short notice purchase
- $200–430
- Business - advance purchase
- $270–1,100
- Business Class
- $380–950
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $80–110
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $100–140
- Website
- https://www.keysshuttle.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $13–19
- Website
- https://www.greyhound.com/
Bus from Buffalo to Cleveland Bus Station
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Estimated price
- $25–45
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Atlanta Bus Station
- Ave. Duration
- 20h 10m
- Frequency
- Once daily
- Estimated price
- $85–160
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 14h 5m
- Frequency
- Once daily
- Estimated price
- $70–170
- Website
- https://www.greyhound.com/
- Phone
- +1 814-574-1827
- Website
- fullingtontours.com
Bus from Buffalo to Pittsburgh
- Ave. Duration
- 7h 30m
- Frequency
- Once daily
- Estimated price
- $110–160
- Website
- https://www.fullingtontours.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Buffalo to Pittsburgh
- Ave. Duration
- 7h 30m
- Frequency
- Once daily
- Estimated price
- $40–180
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $40–170
- Flexible
- $80–180
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 283+ hotels available in Key Largo.










