There are 6 ways to get from Buffalo to Key Largo by plane, shuttle, bus (Greyhound, Flixbus), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Fort Lauderdale–Hollywood International Airport, shuttle
best- Fly from Buffalo Niagara International Airport (BUF) to Fort Lauderdale–Hollywood International Airport (FLL)plane BUF - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
6h 58m$276–668Bus
cheapest- Take the bus from Buffalo, NY to Youngstown, OHbus
- Take the bus from Youngstown Bus Stop to Washington Union Stationbus
- Take the bus from Washington Union Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
36h 20m$215–415Train, bus
- Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
40h 35m$526–1,142Drive 1,439.3 mi
- Drive from Buffalo to Key Largocar 1,439.3 mi
24h 16m$263–380Fly to Miami International Airport, shuttle
- Fly from Buffalo Niagara International Airport (BUF) to Miami International Airport (MIA)plane BUF - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
7h 13m$226–758Bus, train
- Take the bus from Buffalo, Ny to Pittsburgh, Pabus 530
- Take the train from Pittsburgh Amtrak Station to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
2d$502–1,235
Buffalo to Key Largo by bus
Questions & Answers
The cheapest way to get from Buffalo to Key Largo is to bus which costs $210 - $420 and takes 36h 20m.
The fastest way to get from Buffalo to Key Largo is to fly and shuttle which takes 6h 58m and costs $270 - $700.
No, there is no direct bus from Buffalo to Key Largo. However, there are services departing from Buffalo, NY and arriving at Key Largo Bus Stop via Youngstown Bus Stop, Washington Union Station and Miami Airport Station. The journey, including transfers, takes approximately 36h 20m.
The distance between Buffalo and Key Largo is 1269 miles. The road distance is 1447.7 miles.
The best way to get from Buffalo to Key Largo without a car is to bus which takes 36h 20m and costs $210 - $420.
It takes approximately 6h 58m to get from Buffalo to Key Largo, including transfers.
Buffalo to Key Largo bus services, operated by Barons Bus, depart from Buffalo, NY station.
Buffalo to Key Largo bus services, operated by Barons Bus, arrive at Youngstown, OH station.
Yes, the driving distance between Buffalo to Key Largo is 1448 miles. It takes approximately 24h 16m to drive from Buffalo to Key Largo.
Book your Buffalo to Key Largo bus tickets online with Omio.
What companies run services between Buffalo, NY, USA and Key Largo, FL, USA?
You can take a bus from Buffalo, NY to Key Largo Bus Stop via Youngstown, OH, Youngstown Bus Stop, Washington Union Station, and Miami Airport Station in around 36h 20m.
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 15m
- When
- Saturday
- Estimated price
- $120–600
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Orlando
- Ave. Duration
- 5h 3m
- When
- Tuesday, Wednesday, Sunday, Monday, Thursday, and Friday
- Estimated price
- $120–600
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Baltimore
- Ave. Duration
- 5h 12m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $120–600
Flights from Buffalo Niagara International Airport to Miami International Airport via Orlando
- Ave. Duration
- 5h 20m
- When
- Sunday, Monday, Thursday, Friday, and Saturday
- Estimated price
- $120–600
Flights from Buffalo Niagara International Airport to Miami International Airport via Baltimore
- Ave. Duration
- 5h 12m
- When
- Tuesday to Friday
- Estimated price
- $120–600
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Miami International Airport
- Ave. Duration
- 3h 43m
- When
- Saturday
- Estimated price
- $120–600
Flights from Buffalo Niagara International Airport to Miami International Airport via Charlotte
- Ave. Duration
- 6h 36m
- When
- Every day
- Estimated price
- $120–600
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 59m
- When
- Every day
- Estimated price
- $120–600
- Website
- united.com
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Washington Dulles
- Ave. Duration
- 4h 58m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $120–600
Flights from Buffalo Niagara International Airport to Miami International Airport via Washington Dulles
- Ave. Duration
- 5h 11m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $120–600
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Atlanta
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $130–600
- Website
- flyfrontier.com
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Atlanta
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $150–490
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Buffalo to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 8h 17m
- Frequency
- 3 times a day
- Estimated price
- $120–270
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Hollywood Amtrak Station
- Ave. Duration
- 27h 51m
- Frequency
- Once daily
- Estimated price
- $390–850
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Hollywood Amtrak Station
- Ave. Duration
- 36h 21m
- Frequency
- Once daily
- Estimated price
- $440–1,000
- Website
- Amtrak
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $120–150
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $100–130
- Website
- Keys Shuttle
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- Barons Bus
Bus from Buffalo, NY to Youngstown, OH
- Ave. Duration
- 2h 55m
- Frequency
- Once daily
- Estimated price
- $17–55
- Website
- Barons Bus
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Youngstown Bus Stop to Washington Union Station
- Ave. Duration
- 7h 25m
- Frequency
- Once daily
- Estimated price
- $40–85
- Website
- Greyhound
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $8–16
- Website
- Greyhound
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $8–16
- Website
- Greyhound
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $8–16
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Washington Union Station to Miami Airport Station
- Ave. Duration
- 21h 40m
- Frequency
- 4 times a week
- Estimated price
- $150–260
- Schedules at
- Flixbus USA
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Buffalo, Ny to Pittsburgh, Pa
- Saver
- $50–210
- Flexible
- $90–220
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 336+ hotels available in Key Largo.















