There are 5 ways to get from Buffalo to Irvine by plane, train (Amtrak), bus (Greyhound), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to John Wayne Airport Orange County
best- Fly from Buffalo Niagara International Airport (BUF) to John Wayne Airport Orange County (SNA)BUF - SNA
8h 30m$314–1,480Fly to Los Angeles International Airport, train
cheapest- Fly from Buffalo Niagara International Airport (BUF) to Los Angeles International Airport (LAX)BUF - LAX
- Take the train from L.A. Union Station to Tustin
10h 5m$223–1,005Train (Amtrak)
- Take the train from Buffalo Depew Station to Chicago Union StationLake Shore Limited
- Take the train from Chicago Union Station to Fullerton Amtrak StationSouthwest Chief
2d 8h$379–1,781Bus
- Take the bus from Buffalo to Cleveland Bus Station
- Take the bus from Cleveland Bus Station to Chicago Bus Station
- Take the bus from Chicago Bus Station to Denver Union Station
- Take the bus from Denver Union Station to Las Vegas BusTerminal
- Take the bus from Las Vegas BusTerminal to Santa Ana Bus Stop
2d 10h$235–649Drive 2,528.7 mi
- Drive from Buffalo to Irvine2,528.7 mi
40h$462–667
Buffalo to Irvine by train (Amtrak)
Questions & Answers
The cheapest way to get from Buffalo to Irvine is to bus which costs $230 - $650 and takes 2 days 10h.
The fastest way to get from Buffalo to Irvine is to fly which takes 8h 30m and costs $310 - $1,500.
No, there is no direct bus from Buffalo to Irvine. However, there are services departing from Buffalo and arriving at Campus-University Center via Cleveland Bus Station, Chicago Bus Station, Denver Union Station, Las Vegas BusTerminal and The Depot At Santa Ana Dock 3. The journey, including transfers, takes approximately 2 days 10h.
No, there is no direct train from Buffalo to Irvine. However, there are services departing from Buffalo and arriving at Tustin via Buffalo Depew Station, Chicago Union Station and Fullerton. The journey, including transfers, takes approximately 2 days 8h.
The distance between Buffalo and Irvine is 2217 miles. The road distance is 2543.5 miles.
The best way to get from Buffalo to Irvine without a car is to train which takes 2 days 8h and costs $370 - $1,800.
It takes approximately 8h 30m to get from Buffalo to Irvine, including transfers.
Buffalo to Irvine bus services, operated by Greyhound USA, depart from Buffalo station.
Buffalo to Irvine train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from Buffalo to Irvine is to fly which takes 8h 30m and costs $310 - $1,500. Alternatively, you can train, which costs $370 - $1,800 and takes 2 days 8h, you could also bus, which costs $230 - $650 and takes 2 days 10h.
What companies run services between Buffalo, NY, USA and Irvine, CA, USA?
Southwest Airlines, Delta, and two other airlines fly from Buffalo Niagara International Airport (BUF) to John Wayne Airport Orange County (SNA) every 4 hours. Alternatively, you can take a train from Buffalo to Tustin via Buffalo Depew Station, Chicago Union Station, Fullerton Amtrak Station, and Fullerton in around 2d 8h.
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to John Wayne Airport Orange County via Denver
- Ave. Duration
- 8h 20m
- When
- Monday and Saturday
- Estimated price
- $310–1,400
Flights from Buffalo Niagara International Airport to John Wayne Airport Orange County via Las Vegas
- Ave. Duration
- 7h 58m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $310–1,400
Flights from Buffalo Niagara International Airport to John Wayne Airport Orange County via Phoenix
- Ave. Duration
- 7h 30m
- When
- Friday to Sunday
- Estimated price
- $310–1,400
Flights from Buffalo Niagara International Airport to Los Angeles International Airport via Chicago Midway
- Ave. Duration
- 7h 26m
- When
- Monday to Saturday
- Estimated price
- $200–900
Flights from Buffalo Niagara International Airport to Los Angeles International Airport via Las Vegas
- Ave. Duration
- 7h 30m
- When
- Monday
- Estimated price
- $200–900
Flights from Buffalo Niagara International Airport to Los Angeles International Airport via Denver
- Ave. Duration
- 7h 20m
- When
- Monday, Tuesday, and Friday
- Estimated price
- $200–900
Flights from Buffalo Niagara International Airport to Los Angeles International Airport via Phoenix
- Ave. Duration
- 8h 7m
- When
- Monday and Saturday
- Estimated price
- $200–900
Flights from Buffalo Niagara International Airport to Los Angeles International Airport via Dallas
- Ave. Duration
- 8h 5m
- When
- Friday to Sunday
- Estimated price
- $220–950
- Website
- united.com
Flights from Buffalo Niagara International Airport to John Wayne Airport Orange County via Denver
- Ave. Duration
- 7h 41m
- When
- Every day
- Estimated price
- $310–1,400
Flights from Buffalo Niagara International Airport to John Wayne Airport Orange County via Chicago O'Hare
- Ave. Duration
- 7h 52m
- When
- Every day
- Estimated price
- $310–1,400
Flights from Buffalo Niagara International Airport to Los Angeles International Airport via Denver
- Ave. Duration
- 7h 38m
- When
- Every day
- Estimated price
- $200–900
- Website
- delta.com
Flights from Buffalo Niagara International Airport to John Wayne Airport Orange County via Detroit
- Ave. Duration
- 7h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $310–1,400
Flights from Buffalo Niagara International Airport to Los Angeles International Airport via Detroit
- Ave. Duration
- 7h 44m
- When
- Every day
- Estimated price
- $200–900
- Website
- aa.com
Flights from Buffalo Niagara International Airport to John Wayne Airport Orange County via Chicago O'Hare
- Ave. Duration
- 9h 59m
- When
- Every day
- Estimated price
- $310–1,400
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to Los Angeles International Airport
- Ave. Duration
- 5h 30m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $200–900
- Website
- suncountry.com
Flights from Buffalo Niagara International Airport to Los Angeles International Airport via Minneapolis
- Ave. Duration
- 8h 20m
- When
- Thursday
- Estimated price
- $200–900
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo Depew Station to Chicago Union Station
- Ave. Duration
- 10h 33m
- Frequency
- Twice daily
- Estimated price
- $65–200
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Fullerton Amtrak Station
- Ave. Duration
- 42h 44m
- Frequency
- Twice daily
- Estimated price
- $300–1,500
- Website
- https://www.amtrak.com/home.html
- Phone
- (800) 371-LINK (5465)
- Website
- metrolinktrains.com
Train from L.A. Union Station to Tustin
- Ave. Duration
- 1h 1m
- Frequency
- Every 3 hours
- Estimated price
- $8–11
- Website
- https://metrolinktrains.com
- Passenger
- $8–11
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Buffalo to Cleveland Bus Station
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Estimated price
- $27–60
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Chicago Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- Twice daily
- Estimated price
- $40–90
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Denver Union Station
- Ave. Duration
- 21h 14m
- Frequency
- Once daily
- Estimated price
- $80–270
- Website
- https://www.greyhound.com/
Bus from Denver Union Station to Las Vegas BusTerminal
- Ave. Duration
- 15h 30m
- Frequency
- Once daily
- Estimated price
- $60–150
- Website
- https://www.greyhound.com/
Bus from Las Vegas BusTerminal to Santa Ana Bus Stop
- Ave. Duration
- 5h 30m
- Frequency
- Twice daily
- Estimated price
- $35–80
- Website
- https://www.greyhound.com/
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Cleveland Bus Station to Chicago Bus Station
- Ave. Duration
- 7h 35m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- https://baronsbus.com
Want to know more about travelling around United States
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More Questions & Answers
Buffalo to Irvine bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Irvine is 3h behind Buffalo. It is currently 12:26 AM in Buffalo and 9:26 PM in Irvine.
Buffalo to Irvine train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Buffalo to Irvine is 2544 miles. It takes approximately 40h to drive from Buffalo to Irvine.
There are 1306+ hotels available in Irvine.













