Rome2Rio

How to get fromBuffalo to Irvineby plane, train (Amtrak), bus (Greyhound), car or train

Find Transport to Irvine

See all options

There are 5 ways to get from Buffalo to Irvine by plane, train (Amtrak), bus (Greyhound), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to John Wayne Airport Orange County

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to John Wayne Airport Orange County (SNA)plane plane BUF - SNA
    8h 10m
    $334–1,480

  2. Fly to Los Angeles International Airport, train

    cheapest
    1. Fly from Buffalo Niagara International Airport (BUF) to Los Angeles International Airport (LAX)plane plane BUF - LAX
    2. Take the train from L.A. Union Station to Tustintrain train
    10h 5m
    $233–1,005

  3. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train Southwest Chief
    2d 8h
    $379–1,781

  4. Bus

    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Denver Union Stationbus bus
    4. Take the bus from Denver Union Station to Las Vegas BusTerminalbus bus
    5. Take the bus from Las Vegas BusTerminal to Santa Ana Bus Stopbus bus
    2d 10h
    $235–649

  5. Drive 2,528.7 mi

    1. Drive from Buffalo to Irvinecar car 2,528.7 mi
    40h
    $462–667

Buffalo to Irvine by train (Amtrak)

Calendar13Weekly Trains
Duration2d 8hAverage Duration
Ticket$379Cheapest Price
See schedules

Questions & Answers

What companies run services between Buffalo, NY, USA and Irvine, CA, USA?

Southwest Airlines, Delta, and two other airlines fly from Buffalo Niagara International Airport (BUF) to John Wayne Airport Orange County (SNA) 5 times a day. Alternatively, you can take a train from Buffalo to Tustin via Buffalo Depew Station, Chicago Union Station, Fullerton Amtrak Station, and Fullerton in around 2d 8h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Trips from Buffalo

Trips to Irvine

Popular routes