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How to get fromBuffalo to Iowaby plane, train, bus, bus (Greyhound) or car

Find Transport to Iowa

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There are 8 ways to get from Buffalo to Iowa by plane, train, bus, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Des Moines

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Des Moines (DSM)plane plane BUF - DSM
    5h 59m
    $271–1,501

  2. Bus

    cheapest
    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    19h 44m
    $105–256

  3. Train, bus

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123 / ...
    19h 38m
    $132–395

  4. Drive 847.2 mi

    1. Drive from Buffalo to Des Moinescar car 847.2 mi
    14h 14m
    $155–224

  5. Fly to Omaha

    1. Fly from Buffalo Niagara International Airport (BUF) to Omaha (OMA)plane plane BUF - OMA
    6h 7m
    $259–1,310

  6. Fly to Waterloo Municipal Airport

    1. Fly from Buffalo Niagara International Airport (BUF) to Waterloo Municipal Airport (ALO)plane plane BUF - ALO
    5h 54m
    $141–751

  7. Fly to Quad City International Airport

    1. Fly from Buffalo Niagara International Airport (BUF) to Quad City International Airport (MLI)plane plane BUF - MLI
    7h 14m
    $116–732

  8. Fly to The Eastern Iowa Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to The Eastern Iowa Airport (CID)plane plane BUF - CID
    2. Take the bus from GTC Bay 9 to Court St Transportation Centerbus bus
    8h 41m

Buffalo Niagara International Airport (BUF) to Des Moines (DSM) flights

Calendar60Weekly Planes
Duration6h 16mAverage Duration
Ticket$250Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Iowa, USA?

Delta, American Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Des Moines (DSM) every 3 hours. Alternatively, you can take a bus from Buffalo to Des Moines via Cleveland Bus Station, Chicago Bus Station, and Des Moines in around 19h 44m.

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