There are 6 ways to get from Buffalo to Indianapolis by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  5 h 30 min

  1. Fly from Buffalo (BUF) to Indianapolis (IND) BUF - IND

$166 - $448

Cheapest option

Bus  •  11 h 47 min

  1. Take the bus from Buffalo, Ny to Cleveland, Oh 248
  2. Take the bus from Cleveland, Oh to Columbus, Oh
  3. Take the bus from Columbus, OH to Richmond, IN
  4. Take the bus from Richmond, IN to Indianapolis, IN

$71 - $159

4 alternative options

Bus via Cincinnati, Oh  •  11 h 39 min

  1. Take the bus from Buffalo, Ny to Cleveland, Oh 248
  2. Take the bus from Cleveland, Oh to Columbus, Oh
  3. Take the bus from Columbus, Oh to Cincinnati, Oh
  4. Take the bus from University of Cincinnati to Indianapolis, IN

$72 - $171

Train  •  17 h 39 min

  1. Take the train from Buffalo Depew Station Amtrak to Chicago Union Station Amtrak Lake Shore Limited
  2. Take the train from Chicago Union Station Amtrak to Indianapolis Amtrak Hoosier State / ...

$134 - $368

Train, bus  •  20 h 12 min

  1. Take the train from Buffalo to Aldershot
  2. Take the train from Aldershot to London
  3. Take the bus from London, ON to Ann Arbor, MI
  4. Take the bus from Ann Arbor, MI to Indianapolis, IN

$115 - $286

Drive  •  8 h 26 min

  1. Drive from Buffalo to Indianapolis 503.2 miles

$45 - $75

Questions & Answers

The cheapest way to get from Buffalo to Indianapolis is to drive which costs $45 - $75 and takes 8 h 26 min.

More details

The quickest way to get from Buffalo to Indianapolis is to fly which costs $160 - $450 and takes 5 h 30 min.

More details

The distance between Buffalo and Indianapolis is 437 miles. The road distance is 503.2 miles.

Get driving directions

It takes approximately 5 h 30 min to get from Buffalo to Indianapolis, including transfers.

More details

No, there is no direct bus from Buffalo to Indianapolis. However, there are services departing from Buffalo, Ny and arriving at Indianapolis, IN via Cleveland, Oh, Columbus, Oh, Main St & Court St and University of Cincinnati. The journey, including transfers, takes approximately 11 h 39 min.

More details

No, there is no direct train from Buffalo to Indianapolis. However, there are services departing from Buffalo and arriving at Indianapolis Amtrak via Buffalo Depew Station Amtrak and Chicago Union Station Amtrak. The journey, including transfers, takes approximately 17 h 39 min.

More details

What companies run services between Buffalo, NY, USA and Indianapolis, IN, USA?

Delta, Southwest Airlines and two other airlines fly from Buffalo to Indianapolis hourly. Alternatively, you can take a bus from Buffalo to Indianapolis via Cleveland, Oh, Columbus, Oh, Cincinnati, Oh, Main St & Court St, Jefferson Ave & University Ave, and University of Cincinnati in around 11 h 39 min.

Airlines
Delta
Website
delta.com
Flights from Buffalo to Indianapolis via Detroit
Ave. Duration
3 h 18 min
When
Every day
Estimated price
$170 - $700
Flights from Buffalo to Indianapolis via Atlanta
Ave. Duration
4 h 30 min
When
Every day
Estimated price
$170 - $700
Flights from Buffalo to Indianapolis via New York La Guardia
Ave. Duration
4 h 43 min
When
Monday to Friday
Estimated price
$170 - $700
United Airlines
Website
united.com
Flights from Buffalo to Indianapolis via Washington Dulles
Ave. Duration
4 h 9 min
When
Every day
Estimated price
$170 - $750
Flights from Buffalo to Indianapolis via Chicago O'Hare
Ave. Duration
4 h 9 min
When
Every day
Estimated price
$170 - $750
American Airlines
Website
aa.com
Flights from Buffalo to Indianapolis via Chicago O'Hare
Ave. Duration
3 h 54 min
When
Every day
Estimated price
$170 - $850
Flights from Buffalo to Indianapolis via Reagan Washington
Ave. Duration
4 h 10 min
When
Monday to Saturday
Estimated price
$170 - $850
Flights from Buffalo to Indianapolis via Philadelphia
Ave. Duration
4 h 21 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$170 - $850
Flights from Buffalo to Indianapolis via Charlotte
Ave. Duration
4 h 29 min
When
Every day
Estimated price
$170 - $850
Southwest Airlines
Website
southwest.com
Flights from Buffalo to Indianapolis via Baltimore
Ave. Duration
3 h 55 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$390 - $750
Flights from Buffalo to Indianapolis via Chicago Midway
Ave. Duration
3 h 55 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$390 - $750
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Buffalo Depew Station Amtrak to Chicago Union Station Amtrak
Ave. Duration
10 h 31 min
Frequency
Twice daily
Estimated price
$75 - $220
Website
amtrak.com
Coach Seat
$75 - $120
Flexi Coach Seat
$140 - $200
Business Coach Seat
$150 - $220
Room
$330 - $460
Train from Chicago Union Station Amtrak to Indianapolis Amtrak
Ave. Duration
4 h 54 min
Frequency
Once daily
Estimated price
$40 - $100
Website
amtrak.com
Coach Seat
$40 - $60
Flexi Coach Seat
$70 - $110
Business Coach Seat
$70 - $100
Room
$200 - $280
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Buffalo to Aldershot
Ave. Duration
4 h 16 min
Frequency
Every 3 hours
Estimated price
$25 - $75
Website
viarail.ca
Escape
$25 - $35
Economy
$30 - $45
Economy Plus
$50 - $75
Business
$45 - $65
Business Plus/Sleeper
$80 - $120
Train from Aldershot to London
Ave. Duration
1 h 32 min
Frequency
Every 30 minutes
Estimated price
$25 - $75
Website
viarail.ca
Escape
$25 - $40
Economy
$30 - $50
Economy Plus
$50 - $75
Business
$45 - $70
Business Plus/Sleeper
$85 - $130
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Buffalo, Ny to Cleveland, Oh
Ave. Duration
3 h 15 min
Frequency
Hourly
Estimated price
$23 - $60
Website
greyhound.com
Economy
$23 - $40
Flexible
$40 - $60
Bus from Cleveland, Oh to Columbus, Oh
Ave. Duration
2 h 25 min
Frequency
Hourly
Estimated price
$19 - $50
Website
greyhound.com
Economy
$19 - $30
Flexible
$35 - $50
Bus from Columbus, Oh to Cincinnati, Oh
Ave. Duration
1 h 55 min
Frequency
Hourly
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $25
Flexible
$29 - $40
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from University of Cincinnati to Indianapolis, IN
Ave. Duration
1 h 35 min
Frequency
4 times a day
Estimated price
$12 - $22
Schedules at
us.megabus.com
Barons Bus
Website
baronsbus.com
Bus from Columbus, OH to Richmond, IN
Ave. Duration
2 h 10 min
Frequency
3 times a day
Estimated price
$15 - $28
Schedules at
baronsbus.com
Bus from Richmond, IN to Indianapolis, IN
Ave. Duration
1 h 33 min
Frequency
Once daily
Estimated price
$13 - $25
Schedules at
baronsbus.com
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from London, ON to Ann Arbor, MI
Ave. Duration
3 h 41 min
Frequency
Once daily
Estimated price
$20 - $50
Website
Greyhound.ca
Advanced Purchase
$20 - $29
Online Fare
$24 - $45
Standard Fare
$30 - $50
Refundable
$35 - $55

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