There are 6 ways to get from Buffalo to Hyannis by plane, bus (Flixbus, Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Barnstable Municipal Airport
best- Fly from Buffalo Niagara International Airport (BUF) to Barnstable Municipal Airport (HYA)plane BUF - HYA
4h 38m$126–828Bus
cheapest- Take the bus from Buffalo to Syracuse Bus Stationbus
- Take the bus from Syracuse Bus Station to Bostonbus
- Take the bus from Boston South Station to Hyannis Transportation Centerbus
14h 5m$64–182Train, bus
- Take the train from Buffalo Depew Station to Bostontrain Lake Shore Limited
- Take the bus from Boston South Station to Hyannis Transportation Centerbus Boston
15h 19m$129–365Drive 512.7 mi
- Drive from Buffalo to Hyanniscar 512.7 mi
9h 3m$94–136Fly to Boston Logan Airport, bus
- Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane BUF - BOS
- Take the bus from Logan International Airport to Hyannis Transportation Centerbus
5h 30m$134–768Bus via New York
- Take the bus from Buffalo to New Yorkbus
- Take the bus from Port Authority Bus Terminal to Peter Pan Bus Terminalbus
- Take the bus from Providence Bus Terminal to Hyannis Transportation Centerbus
15h 45m$98–368
Buffalo to Hyannis by bus
Questions & Answers
The cheapest way to get from Buffalo to Hyannis is to drive which costs $90 - $140 and takes 9h 3m.
The fastest way to get from Buffalo to Hyannis is to fly which takes 4h 38m and costs $120 - $850.
No, there is no direct bus from Buffalo to Hyannis. However, there are services departing from Buffalo and arriving at Hyannis Transportation Center via Syracuse Bus Station and Boston South Station. The journey, including transfers, takes approximately 14h 5m.
The distance between Buffalo and Hyannis is 453 miles. The road distance is 515.7 miles.
The best way to get from Buffalo to Hyannis without a car is to bus which takes 14h 5m and costs $60 - $190.
It takes approximately 4h 38m to get from Buffalo to Hyannis, including transfers.
Buffalo to Hyannis bus services, operated by Flixbus USA, depart from Buffalo station.
The best way to get from Buffalo to Hyannis is to fly which takes 4h 38m and costs $120 - $850. Alternatively, you can bus, which costs $60 - $190 and takes 14h 5m.
Buffalo to Hyannis bus services, operated by Flixbus USA, arrive at Syracuse Bus Station.
Yes, the driving distance between Buffalo to Hyannis is 516 miles. It takes approximately 9h 3m to drive from Buffalo to Hyannis.
What companies run services between Buffalo, NY, USA and Hyannis, MA, USA?
JetBlue Airways, Cape Air, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Barnstable Municipal Airport (HYA) every 4 hours. Alternatively, you can take a bus from Buffalo to Hyannis Transportation Center via Syracuse Bus Station, Boston, and Boston South Station in around 14h 5m.
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to Barnstable Municipal Airport via Boston Logan Airport
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- $120–800
Flights from Buffalo Niagara International Airport to Barnstable Municipal Airport via New York JFK
- Ave. Duration
- 5h 14m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $130–800
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $100–700
Flights from Buffalo Niagara International Airport to Boston Logan Airport via New York JFK
- Ave. Duration
- 3h 48m
- When
- Monday, Tuesday, Wednesday, and Sunday
- Estimated price
- $110–750
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Barnstable Municipal Airport via Reagan Washington
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $160–900
Flights from Buffalo Niagara International Airport to Barnstable Municipal Airport via New York La Guardia
- Ave. Duration
- 5h 39m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–800
Flights from Buffalo Niagara International Airport to Barnstable Municipal Airport via Philadelphia
- Ave. Duration
- 6h 41m
- When
- Every day
- Estimated price
- $140–850
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $100–700
- Website
- capeair.com
Flights from Buffalo Niagara International Airport to Barnstable Municipal Airport via Boston Logan Airport
- Ave. Duration
- 3h 23m
- When
- Friday to Sunday
- Estimated price
- $120–800
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 35m
- When
- Saturday
- Estimated price
- $130–800
- Website
- united.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport via Newark
- Ave. Duration
- 3h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–750
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 3h 48m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–750
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo Depew Station to Boston
- Ave. Duration
- 11h 27m
- Frequency
- Once daily
- Estimated price
- $110–250
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 2h 50m
- Frequency
- Every 4 hours
- Estimated price
- $18–35
- Schedules at
- flixbus.com
Bus from Syracuse Bus Station to Boston
- Ave. Duration
- 6h 30m
- Frequency
- 5 times a week
- Estimated price
- $35–65
- Schedules at
- flixbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Every 4 hours
- Estimated price
- $28–95
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $28–90
- Flexible
- $55–95
Bus from Buffalo to New York
- Ave. Duration
- 7h 55m
- Frequency
- 5 times a day
- Estimated price
- $60–280
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $60–260
- Flexible
- $110–280
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 3h 5m
- Frequency
- 4 times a day
- Estimated price
- $25–50
- Website
- https://www.greyhound.com/
Bus from Syracuse Bus Station to Boston
- Ave. Duration
- 7h 40m
- Frequency
- Once daily
- Estimated price
- $50–95
- Website
- https://www.greyhound.com/
- Phone
- 1-800-343-9999
- Website
- peterpanbus.com
Bus from Boston South Station to Hyannis Transportation Center
- Ave. Duration
- 1h 35m
- Frequency
- Every 3 hours
- Estimated price
- $10–40
- Website
- https://peterpanbus.com
- Adult
- $10–40
Bus from Port Authority Bus Terminal to Peter Pan Bus Terminal
- Ave. Duration
- 4h
- Frequency
- Every 4 hours
- Estimated price
- $25–55
- Website
- https://peterpanbus.com
- Adult
- $25–55
Bus from Providence Bus Terminal to Hyannis Transportation Center
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Estimated price
- $11–40
- Website
- https://peterpanbus.com
- Adult
- $11–40
- Phone
- +1 (508) 746-0378
- info@p-b.com
- Website
- p-b.com
Bus from Logan International Airport to Hyannis Transportation Center
- Ave. Duration
- 2h 15m
- Frequency
- Hourly
- Estimated price
- $28–40
- Website
- https://www.p-b.com
- One Way - Adult
- $28–40
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