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How to get fromBuffalo to Hyannisby plane, bus (Flixbus, Greyhound), train, bus, car or bus (Flixbus)

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There are 7 ways to get from Buffalo to Hyannis by plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Barnstable Municipal Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Barnstable Municipal Airport (HYA)planeBUF - HYA
    4h 38m
    $114–730

  2. Train, bus

    cheapest
    1. Take the train from Buffalo Depew Station to BostontrainLake Shore Limited
    2. Take the bus from Boston South Station to Hyannis Transportation CenterbusBoston
    15h 19m
    $74–354

  3. Bus

    1. Take the bus from Buffalo to Syracuse Bus Stationbus
    2. Take the bus from Syracuse Bus Station to Bostonbus
    3. Take the bus from Boston South Station to Hyannis Transportation Centerbus
    13h 20m
    $82–209

  4. Drive 512.7 mi

    1. Drive from Buffalo to Hyanniscar512.7 mi
    9h 1m
    $94–136

  5. Fly to Boston Logan Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)planeBUF - BOS
    2. Take the bus from Logan International Airport to Hyannis Transportation Centerbus
    5h 30m
    $132–770

  6. Fly to Provincetown Municipal Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Provincetown Municipal Airport (PVC)planeBUF - PVC
    2. Take the bus from Provincetown to Hyannis Transportation Centerbus
    18h 21m
    $351–1,335

  7. Bus via Ithaca

    1. Take the bus from Buffalo to Ithacabus
    2. Take the bus from Ithaca to Bostonbus
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus
    15h 7m
    $128–223

Buffalo to Hyannis by bus

Calendar13Weekly Buses
Duration13h 20mAverage Duration
Ticket$82Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Hyannis, MA, USA?

JetBlue Airways, American Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Barnstable Municipal Airport (HYA) 5 times a day. Alternatively, you can take a bus from Buffalo to Hyannis Transportation Center via Syracuse Bus Station, Boston, and Boston South Station in around 13h 20m.

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