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How to get fromBuffalo to Hopkintonby plane, train, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

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There are 6 ways to get from Buffalo to Hopkinton by plane, train, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport, train

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    2. Take the train from Back Bay to Southboroughtrain train
    6h 29m
    $77–414

  2. Bus (Greyhound)

    1. Take the bus from Buffalo to Bostonbus bus Greyhound US0171
    13h 34m
    $88–130

  3. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Framingham Amtraktrain train Lake Shore Limited
    14h 17m
    $255–542

  4. Drive  431.6 mi

    1. Drive from Buffalo to Hopkintoncar car 431.6 mi
    7h 29m
    $79–114

  5. Bus to Rochester, fly, train

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane plane ROC - BOS
    3. Take the train from Back Bay to Southboroughtrain train
    7h 38m
    $125–615

  6. Bus via Ithaca

    1. Take the bus from Buffalo to Ithacabus bus
    2. Take the bus from Ithaca to Albany Bus Terminal, NYbus bus
    3. Take the bus from Albany Bus Terminal, NY to Worcester Union Stationbus bus
    15h 49m
    $81–149

Buffalo to Hopkinton by bus (Greyhound)

Calendar7Weekly Buses
Duration13h 34mAverage Duration
Ticket$88Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Hopkinton.ExpandLaunch map view
  • Distance: 446.2 mi
  • Duration: 6h 29m

What companies run services between Buffalo, NY, USA and Hopkinton, MA, USA?

Greyhound USA operates a bus from Buffalo to Boston once daily. Tickets cost $80–130 and the journey takes 10h 5m. Alternatively, Amtrak operates a train from Buffalo Depew Station to Framingham Amtrak once daily. Tickets cost $250–400 and the journey takes 10h 53m.

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Need to know: Greyhound

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