Rome2Rio

How to get fromBuffalo to Florida Keysby plane, bus, train, car, shuttle or ferry

Find Transport to Florida Keys

See all options

There are 8 ways to get from Buffalo to Florida Keys by plane, bus, train, car, shuttle, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Key West International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Key West International Airport (EYW)planeBUF - EYW
    9h 25m
    $251–1,099

  2. Bus, train via Newark

    1. Take the bus from Buffalo to Newark Penn Stationbus
    2. Take the train from Newark Penn Station to Miami Amtrak Stationtrain
    3. Take the bus from Miami Airport Station to Big Pine Keybus
    42h 54m
    $291–1,290

  3. Drive 1,521.1 mi

    1. Drive from Buffalo to Florida Keyscar1,521.1 mi
    25h 54m
    $278–401

  4. Fly Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Buffalo Niagara International Airport (BUF) to Fort Lauderdale–Hollywood International Airport (FLL)planeBUF - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle
    10h 20m
    $266–834

  5. Shuttle to Toronto Pearson International Airport, fly to Key West International Airport

    1. Take a shuttle bus from Buffalo Airport to Pearson International Airport Terminal 1shuttle
    2. Fly from Toronto Pearson International Airport (YYZ) to Key West International Airport (EYW)planeYYZ - EYW
    12h 44m
    $261–819

  6. Fly Buffalo Niagara International Airport to Ft. Myers, ferry

    1. Fly from Buffalo Niagara International Airport (BUF) to Ft. Myers (RSW)planeBUF - RSW
    2. Take the ferry from Fort Myers Beach, FL to Key West, FLferry
    12h 48m
    $361–1,196

  7. Train, bus

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Stationtrain
    3. Take the bus from Miami Airport Station to Big Pine Keybus
    44h 9m
    $283–978

  8. Bus, train

    1. Take the bus from Buffalo to Pittsburghbus
    2. Take the train from Pittsburgh Amtrak Station to Miami Amtrak Stationtrain
    3. Take the bus from Miami Airport Station to Big Pine Keybus
    2d 3h
    $252–798

Buffalo to Florida Keys by bus, train, taxi, and foot

Calendar7Weekly Services
Duration42h 54mAverage Duration
Ticket$291Cheapest Price
See schedules

Questions & Answers

What companies run services between Buffalo, NY, USA and Florida Keys, FL, USA?

Delta, American Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Key West International Airport (EYW) 5 times a day.

Airlines
Train operators
Bus operators
Ferry operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Buffalo

Trips to Florida Keys

Popular routes