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How to get fromBuffalo to Florida Keysby plane, bus, train, car or shuttle

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There are 8 ways to get from Buffalo to Florida Keys by plane, bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Key West International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Key West International Airport (EYW)plane plane BUF - EYW
    9h 33m
    $271–1,249

  2. Bus to Rochester, fly to Key West International Airport

    cheapest
    1. Take the bus from Buffalo, NY to Rochester, NYbus bus
    2. Fly from Rochester (ROC) to Key West International Airport (EYW)plane plane ROC - EYW
    12h 22m
    $251–1,104

  3. Bus, train via Newark

    1. Take the bus from Buffalo to Newark Penn Stationbus bus
    2. Take the train from Newark Penn Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    43h 4m
    $261–843

  4. Drive 1,521.1 mi

    1. Drive from Buffalo to Florida Keyscar car 1,521.1 mi
    26h 9m
    $278–401

  5. Fly Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Buffalo Niagara International Airport (BUF) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane BUF - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 25m
    $266–884

  6. Shuttle to Toronto Pearson International Airport, fly to Key West International Airport

    1. Take a shuttle bus from Buffalo Airport to Pearson International Airport Terminal 1shuttle bus
    2. Fly from Toronto Pearson International Airport (YYZ) to Key West International Airport (EYW)plane plane YYZ - EYW
    12h 47m
    $391–689

  7. Train, bus

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    44h 9m
    $262–925

  8. Bus, train

    1. Take the bus from Buffalo to Pittsburghbus bus
    2. Take the train from Pittsburgh Amtrak Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    2d 3h
    $252–728

Buffalo to Florida Keys by bus, train, taxi, and foot

Calendar7Weekly Services
Duration43h 4mAverage Duration
Ticket$261Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Florida Keys, FL, USA?

American Airlines, Delta, and three other airlines fly from Buffalo Niagara International Airport (BUF) to Key West International Airport (EYW) 5 times a day.

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