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How to get fromBuffalo to Florida Keysby plane, train, bus, bus (Greyhound, Flixbus), car, or shuttle

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There are 8 ways to get from Buffalo to Florida Keys by plane, train, bus, bus (Greyhound, Flixbus), car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Key West International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Key West International Airport (EYW)plane plane BUF - EYW
    9h 10m
    $233–772

  2. Bus to Rochester, fly to Key West International Airport

    cheapest
    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Key West International Airport (EYW)plane plane ROC - EYW
    10h 40m
    $215–618

  3. Train, bus

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    44h 4m
    $582–1,241

  4. Bus

    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    45h 25m
    $250–530

  5. Drive 1,521.1 mi

    1. Drive from Buffalo to Florida Keyscar car 1,521.1 mi
    26h 10m
    $278–401

  6. Fly Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Buffalo Niagara International Airport (BUF) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane BUF - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 6m
    $348–1,032

  7. Shuttle to Toronto Pearson International Airport, fly to Key West International Airport

    1. Take a shuttle bus from Buffalo Airport to Pearson International Airport Terminal 1shuttle bus
    2. Fly from Toronto Pearson International Airport (YYZ) to Key West International Airport (EYW)plane plane YYZ - EYW
    12h 54m
    $253–592

  8. Bus, train, shuttle

    1. Take the bus from Buffalo, Ny to Pittsburgh, Pabus bus 530
    2. Take the train from Pittsburgh Amtrak Station to Miami Amtrak Stationtrain train
    3. Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Labshuttle bus
    2d 3h
    $697–1,426

Buffalo to Florida Keys by train, taxi, bus, and foot

Calendar7Weekly Services
Duration44h 4mAverage Duration
Ticket$582Cheapest Price
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Questions & Answers

Map of how to get from Buffalo to Florida Keys.ExpandLaunch map view
  • Distance: 1,313.3 mi
  • Duration: 9h 10m

What companies run services between Buffalo, NY, USA and Florida Keys, FL, USA?

Delta and American Airlines fly from Buffalo Niagara International Airport (BUF) to Key West International Airport (EYW) 4 times a day. Alternatively, you can take a bus from Buffalo to Florida Keys via Cleveland Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 45h 25m.

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