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How to get fromBuffalo to Fermilabby plane, taxi, train (Amtrak), bus (Greyhound), car, train or bus

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There are 6 ways to get from Buffalo to Fermilab by plane, taxi, train (Amtrak), bus (Greyhound), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Chicago O'Hare International Airport, taxi

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)planeBUF - ORD
    2. Take the taxi from Chicago-O-Hare-Airport-ORD to Fermilabtaxi
    4h 2m
    $174–630

  2. Drive 561.3 mi

    cheapest
    1. Drive from Buffalo to Fermilabcar561.3 mi
    9h 45m
    $103–148

  3. Train

    1. Take the train from Buffalo Depew Station to Chicago Union StationtrainLake Shore Limited
    2. Take the train from Chicago OTC to West ChicagotrainUp-W
    13h 44m
    $117–305

  4. Bus

    1. Take the bus from Buffalo to Cleveland Bus Stationbus
    2. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus
    3. Take the bus from Chicago to Naperville Amtrak Stationbus
    14h 7m
    $104–230

  5. Fly Buffalo Niagara International Airport to Chicago Midway International Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)planeBUF - MDW
    2. Take the train from Chicago OTC to West Chicagotrain
    5h 47m
    $129–717

  6. Bus to Rochester, fly to Chicago O'Hare International Airport, taxi

    1. Take the bus from Buffalo, NY to Rochester, NYbus
    2. Fly from Rochester (ROC) to Chicago O'Hare International Airport (ORD)planeROC - ORD
    3. Take the taxi from Chicago-O-Hare-Airport-ORD to Fermilabtaxi
    6h 13m
    $249–685

Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD) flights

Calendar90Weekly Planes
Duration3h 17mAverage Duration
Ticket$75Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Fermilab, IL, USA?

You can take a train from Buffalo to Fermilab via Buffalo Depew Station, Chicago Union Station, Chicago OTC, and West Chicago in around 13h 44m. Alternatively, you can take a bus from Buffalo to Fermilab via Cleveland Bus Station, Chicago, and Naperville Amtrak Station in around 14h 7m.

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