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How to get fromBuffalo to Easthamby plane, bus (Flixbus, Greyhound), train, bus or car

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There are 7 ways to get from Buffalo to Eastham by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Barnstable Municipal Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Barnstable Municipal Airport (HYA)plane plane BUF - HYA
    8h 18m
    $140–918

  2. Bus

    cheapest
    1. Take the bus from Buffalo to Syracuse Bus Stationbus bus
    2. Take the bus from Syracuse Bus Station to Bostonbus bus
    3. Take the bus from Boston South Station to Hyannis Transportation Centerbus bus
    15h 45m
    $81–215

  3. Train, bus

    1. Take the train from Buffalo Depew Station to Bostontrain train Lake Shore Limited
    2. Take the bus from Boston South Station to Hyannis Transportation Centerbus bus Boston
    16h 59m
    $159–438

  4. Drive 533.8 mi

    1. Drive from Buffalo to Easthamcar car 533.8 mi
    9h 30m
    $98–141

  5. Fly Buffalo Niagara International Airport to Boston Logan Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    2. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    7h 42m
    $125–655

  6. Bus to Rochester, fly to Boston Logan Airport, bus

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane plane ROC - BOS
    3. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    8h 20m
    $271–850

  7. Train to Toronto Island Airport, fly to Boston Logan Airport, bus

    1. Take the train from Buffalo to Toronto Union Stationtrain train
    2. Fly from Toronto Island Airport (YTZ) to Boston Logan Airport (BOS)plane plane YTZ - BOS
    3. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    12h 18m
    $166–618

Buffalo to Eastham by bus

Calendar12Weekly Buses
Duration15h 45mAverage Duration
Ticket$81Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Eastham, MA, USA?

American Airlines, JetBlue Airways, and Cape Air fly from Buffalo Niagara International Airport (BUF) to Barnstable Municipal Airport (HYA) every 4 hours. Alternatively, you can take a bus from Buffalo to Eastham via Syracuse Bus Station, Boston, Boston South Station, and Hyannis Transportation Center in around 15h 45m.

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