There are 7 ways to get from Buffalo to Eastham by plane, bus (Flixbus, Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Buffalo Niagara International Airport to Barnstable Municipal Airport
best- Fly from Buffalo Niagara International Airport (BUF) to Barnstable Municipal Airport (HYA)plane BUF - HYA
8h 18m$140–918Bus
cheapest- Take the bus from Buffalo to Syracuse Bus Stationbus
- Take the bus from Syracuse Bus Station to Bostonbus
- Take the bus from Boston South Station to Hyannis Transportation Centerbus
15h 45m$81–215Train, bus
- Take the train from Buffalo Depew Station to Bostontrain Lake Shore Limited
- Take the bus from Boston South Station to Hyannis Transportation Centerbus Boston
16h 59m$159–438Drive 533.8 mi
- Drive from Buffalo to Easthamcar 533.8 mi
9h 30m$98–141Fly Buffalo Niagara International Airport to Boston Logan Airport, bus
- Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane BUF - BOS
- Take the bus from Logan International Airport to Hyannis Transportation Centerbus
7h 42m$125–655Bus to Rochester, fly to Boston Logan Airport, bus
- Take the bus from Buffalo to Rochester Bus Stopbus
- Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane ROC - BOS
- Take the bus from Logan International Airport to Hyannis Transportation Centerbus
8h 20m$271–850Train to Toronto Island Airport, fly to Boston Logan Airport, bus
- Take the train from Buffalo to Toronto Union Stationtrain
- Fly from Toronto Island Airport (YTZ) to Boston Logan Airport (BOS)plane YTZ - BOS
- Take the bus from Logan International Airport to Hyannis Transportation Centerbus
12h 18m$166–618
Buffalo to Eastham by bus
Questions & Answers
The cheapest way to get from Buffalo to Eastham is to drive which costs $95 - $150 and takes 9h 30m.
The fastest way to get from Buffalo to Eastham is to fly and bus which takes 7h 42m and costs $120 - $700.
No, there is no direct bus from Buffalo to Eastham. However, there are services departing from Buffalo and arriving at Eastham via Syracuse Bus Station, Boston South Station and Hyannis Transportation Center. The journey, including transfers, takes approximately 15h 45m.
The distance between Buffalo and Eastham is 483 miles. The road distance is 536.9 miles.
The best way to get from Buffalo to Eastham without a car is to bus which takes 15h 45m and costs $80 - $220.
It takes approximately 8h 18m to get from Buffalo to Eastham, including transfers.
Buffalo to Eastham bus services, operated by Flixbus USA, depart from Buffalo station.
The best way to get from Buffalo to Eastham is to fly which takes 8h 18m and costs $140 - $950. Alternatively, you can bus, which costs $80 - $220 and takes 15h 45m.
Buffalo to Eastham bus services, operated by Flixbus USA, arrive at Syracuse Bus Station.
Yes, the driving distance between Buffalo to Eastham is 537 miles. It takes approximately 9h 30m to drive from Buffalo to Eastham.
What companies run services between Buffalo, NY, USA and Eastham, MA, USA?
American Airlines, JetBlue Airways, and Cape Air fly from Buffalo Niagara International Airport (BUF) to Barnstable Municipal Airport (HYA) every 4 hours. Alternatively, you can take a bus from Buffalo to Eastham via Syracuse Bus Station, Boston, Boston South Station, and Hyannis Transportation Center in around 15h 45m.
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Barnstable Municipal Airport via Reagan Washington
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $170–1,000
Flights from Buffalo Niagara International Airport to Barnstable Municipal Airport via New York La Guardia
- Ave. Duration
- 5h 54m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–900
Flights from Buffalo Niagara International Airport to Barnstable Municipal Airport via Philadelphia
- Ave. Duration
- 7h 11m
- When
- Every day
- Estimated price
- $150–950
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $90–600
Flights from Rochester to Boston Logan Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $70–470
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to Barnstable Municipal Airport via Boston Logan Airport
- Ave. Duration
- 5h 36m
- When
- Every day
- Estimated price
- $130–900
Flights from Buffalo Niagara International Airport to Barnstable Municipal Airport via New York JFK
- Ave. Duration
- 8h 13m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $140–900
Flights from Buffalo Niagara International Airport to Boston Logan Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $90–600
- Website
- flyporter.com
Flights from Toronto Island Airport to Boston Logan Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $110–480
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 45m
- When
- Sunday
- Estimated price
- $120–700
Flights from Rochester to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 42m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
- Website
- capeair.com
Flights from Buffalo Niagara International Airport to Barnstable Municipal Airport via Boston Logan Airport
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $130–900
- Website
- united.com
Flights from Rochester to Boston Logan Airport via Newark
- Ave. Duration
- 3h 49m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–550
Flights from Toronto Island Airport to Boston Logan Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $50–340
- Website
- aircanada.com
Flights from Toronto Island Airport to Boston Logan Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $50–340
Flights from Toronto Island Airport to Boston Logan Airport via Montreal
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $60–360
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo Depew Station to Boston
- Ave. Duration
- 11h 27m
- Frequency
- Once daily
- Estimated price
- $130–310
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888 842-7245
- Website
- viarail.ca
Train from Buffalo to Toronto Union Station
- Ave. Duration
- 4h 1m
- Frequency
- Once daily
- Estimated price
- $22–85
- Website
- https://www.viarail.ca/en
- Economy Adult - same day booking
- $25–85
- Economy Adult - Advanced Booking
- $25–70
- Economy Escape Advanced Booking - Adult
- $22–35
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 2h 50m
- Frequency
- Every 4 hours
- Estimated price
- $21–40
- Schedules at
- flixbus.com
Bus from Syracuse Bus Station to Boston
- Ave. Duration
- 6h 30m
- Frequency
- 5 times a week
- Estimated price
- $40–75
- Schedules at
- flixbus.com
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 15m
- Frequency
- Every 3 hours
- Estimated price
- $9–17
- Schedules at
- flixbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Every 4 hours
- Estimated price
- $28–95
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $28–90
- Flexible
- $55–95
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 3h 5m
- Frequency
- 4 times a day
- Estimated price
- $27–55
- Website
- https://www.greyhound.com/
Bus from Syracuse Bus Station to Boston
- Ave. Duration
- 7h 40m
- Frequency
- Once daily
- Estimated price
- $55–110
- Website
- https://www.greyhound.com/
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 25m
- Frequency
- 3 times a day
- Estimated price
- $12–25
- Website
- https://www.greyhound.com/
- Phone
- 1-800-343-9999
- Website
- peterpanbus.com
Bus from Boston South Station to Hyannis Transportation Center
- Ave. Duration
- 1h 35m
- Frequency
- Every 3 hours
- Estimated price
- $15–40
- Website
- https://peterpanbus.com
- Phone
- +1 (508) 746-0378
- info@p-b.com
- Website
- p-b.com
Bus from Logan International Airport to Hyannis Transportation Center
- Ave. Duration
- 2h 15m
- Frequency
- Hourly
- Estimated price
- $28–40
- Website
- https://www.p-b.com/
- One Way - Adult
- $28–40
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 661+ hotels available in Eastham.




















