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How to get fromBuffalo to Durhamby plane, bus, bus (Greyhound, Flixbus), train (Amtrak), car or train

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There are 8 ways to get from Buffalo to Durham by plane, bus, bus (Greyhound, Flixbus), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Raleigh-Durham International Airport, line 700 bus

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Raleigh-Durham International Airport (RDU)plane plane BUF - RDU
    2. Take the bus from Regional Transit Center to Pettigrew St at Parking Deckbus bus
    4h 29m
    $106–681

  2. Bus to Rochester, fly to Raleigh-Durham International Airport

    cheapest
    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Raleigh-Durham International Airport (RDU)plane plane ROC - RDU
    5h 45m
    $78–600

  3. Bus

    1. Take the bus from Buffalo, NY to Youngstown, OHbus bus
    2. Take the bus from Youngstown Bus Stop to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Durhambus bus
    17h 25m
    $97–239

  4. Train (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Stationtrain train Carolinian
    21h 21m
    $273–609

  5. Drive 576.7 mi

    1. Drive from Buffalo to Durhamcar car 576.7 mi
    12h 38m
    $106–152

  6. Fly Buffalo Niagara International Airport to Piedmont Triad International Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Piedmont Triad International Airport (GSO)plane plane BUF - GSO
    2. Take the train from Greensboro to Durham Amtrak Stationtrain train
    6h 59m
    $180–898

  7. Bus via New York

    1. Take the bus from Buffalo to New Yorkbus bus Adt N813 / ...
    2. Take the bus from New York, NY - 201 West x 37th St to Durham, NC - 3446 Hillsborough Rdbus bus New York
    18h 53m
    $108–349

  8. Bus, train

    1. Take the bus from Buffalo to Pittsburghbus bus Fab530
    2. Take the train from Pittsburgh Amtrak Station to Carytrain train Floridian
    24h 58m
    $204–545

Buffalo to Durham by bus

Calendar7Weekly Buses
Duration17h 25mAverage Duration
Ticket$97Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Durham, NC, USA?

You can take a bus from Buffalo, NY to Durham via Youngstown, OH, Youngstown Bus Stop, and Washington Union Station in around 17h 25m. Alternatively, you can take a train from Buffalo to Durham Amtrak Station via Ny Moynihan Train Hall At Penn Station in around 21h 21m.

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