Rome2Rio

How to get fromBuffalo to Durhamby plane, bus, bus (Flixbus), train (Amtrak), car, train or bus (Greyhound)

Find Transport to Durham

See all options

There are 8 ways to get from Buffalo to Durham by plane, bus, bus (Flixbus), train (Amtrak), car, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Raleigh-Durham International Airport, bus, line 700 bus

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Raleigh-Durham International Airport (RDU)plane plane BUF - RDU
    2. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus bus
    3. Take the bus from Regional Transit Center to Pettigrew St at Parking Deckbus bus
    4h 54m
    $102–655

  2. Bus to Rochester, fly to Raleigh-Durham International Airport

    cheapest
    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Raleigh-Durham International Airport (RDU)plane plane ROC - RDU
    5h 34m
    $77–650

  3. Bus (Flixbus)

    1. Take the bus from Buffalo to New York Midtownbus bus FlixBus 2686 / ...
    2. Take the bus from New York Midtown to Durhambus bus FlixBus N2471 / ...
    19h 55m
    $129–232

  4. Train (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Stationtrain train Carolinian
    21h 21m
    $274–606

  5. Drive 576.8 mi

    1. Drive from Buffalo to Durhamcar car 576.8 mi
    12h 37m
    $106–152

  6. Fly Buffalo Niagara International Airport to Piedmont Triad International Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Piedmont Triad International Airport (GSO)plane plane BUF - GSO
    2. Take the train from Greensboro to Durham Amtrak Stationtrain train
    7h 44m
    $186–922

  7. Bus via New York

    1. Take the bus from Buffalo to Port Authority Bus Terminalbus bus Greyhound US0205 / ...
    2. Take the bus from Port Authority Bus Terminal to Durhambus bus Greyhound US0670
    22h 5m
    $152–438

  8. Bus, train

    1. Take the bus from Buffalo to Pittsburghbus bus Fab530
    2. Take the train from Pittsburgh Amtrak Station to Carytrain train Floridian
    24h 58m
    $204–545

Buffalo to Durham by bus (Flixbus)

Calendar19Weekly Buses
Duration19h 55mAverage Duration
Ticket$129Cheapest Price
See schedules

Questions & Answers

What companies run services between Buffalo, NY, USA and Durham, NC, USA?

You can take a bus from Buffalo to Durham via New York Midtown in around 19h 55m. Alternatively, you can take a train from Buffalo to Durham Amtrak Station via Ny Moynihan Train Hall At Penn Station in around 21h 21m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Trips from Buffalo

Trips to Durham

Popular routes