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How to get fromBuffalo to Duke Universityby plane, bus (Flixbus), train (Amtrak), car, bus, shuttle, train or bus (Greyhound)

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There are 10 ways to get from Buffalo to Duke University by plane, bus (Flixbus), train (Amtrak), car, bus, shuttle, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Raleigh-Durham International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Raleigh-Durham International Airport (RDU)planeBUF - RDU
    6h 44m
    $115–784

  2. Bus to Rochester, fly to Raleigh-Durham International Airport

    cheapest
    1. Take the bus from Buffalo, NY to Rochester, NYbus
    2. Fly from Rochester (ROC) to Raleigh-Durham International Airport (RDU)planeROC - RDU
    7h 7m
    $80–429

  3. Bus (Flixbus)

    1. Take the bus from Buffalo to New York MidtownbusFlixBus N2686 / ...
    2. Take the bus from New York Midtown to DurhambusFlixBus N2471 / ...
    20h 21m
    $121–292

  4. Train (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn StationtrainEmpire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak StationtrainCarolinian
    21h 53m
    $169–494

  5. Drive 582.8 mi

    1. Drive from Buffalo to Duke Universitycar582.8 mi
    12h 26m
    $107–154

  6. Shuttle to Toronto Pearson International Airport, fly to Raleigh-Durham International Airport

    1. Take a shuttle bus from Buffalo Airport to Pearson International Airport Terminal 1shuttle
    2. Fly from Toronto Pearson International Airport (YYZ) to Raleigh-Durham International Airport (RDU)planeYYZ - RDU
    8h 52m
    $255–854

  7. Fly Buffalo Niagara International Airport to Piedmont Triad International Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Piedmont Triad International Airport (GSO)planeBUF - GSO
    2. Take the train from Greensboro to Durham Amtrak Stationtrain
    9h 23m
    $180–1,010

  8. Fly Buffalo Niagara International Airport to Charlotte Douglas International Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT)planeBUF - CLT
    2. Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain
    8h 42m
    $136–719

  9. Bus via New York

    1. Take the bus from Buffalo to Port Authority Bus TerminalbusGreyhound US0205 / ...
    2. Take the bus from Port Authority Bus Terminal to DurhambusGreyhound US0670
    22h 41m
    $120–311

  10. Bus, train

    1. Take the bus from Buffalo to Pittsburghbus
    2. Take the train from Pittsburgh Amtrak Station to Raleigh Union Stationtrain
    3. Take the bus from Union Station - Bus Platform A to Chapel Dr at Duke University RdbusDrx
    24h 55m
    $119–725

Buffalo to Duke University by bus and foot (Flixbus)

Calendar38Weekly Services
Duration20h 21mAverage Duration
Ticket$121Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Duke University, NC, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Raleigh-Durham International Airport (RDU) every 2 hours. Alternatively, you can take a bus from Buffalo to Duke University via New York Midtown, Durham, Durham Station, and Flowers Dr at Duke Gardens in around 20h 21m.

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