There are 7 ways to get from Buffalo to Des Moines by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Des Moines  •  6 h 37 min

  1. Fly from Buffalo (BUF) to Des Moines (DSM) BUF - DSM

$156 - $438

Cheapest option

Bus  •  20 h 33 min

  1. Take the bus from Buffalo, Ny to Cleveland, Oh 248
  2. Take the bus from Cleveland, Oh to Chicago Amtrak, Il
  3. Take the bus from Chicago, IL to Des Moines, IA

$111 - $239

5 alternative options

Fly to Waterloo, bus  •  10 h 50 min

  1. Fly from Buffalo (BUF) to Waterloo (ALO) BUF - ALO
  2. Take the bus from Waterloo, IA to Des Moines, IA

$253 - $999

Train, bus  •  19 h 47 min

  1. Take the train from Buffalo Depew Station Amtrak to Chicago Union Station Amtrak Lake Shore Limited
  2. Take the bus from Chicago, IL to Des Moines, IA 1205 / ...

$139 - $348

Train, bus via Ottumwa, IA  •  21 h 18 min

  1. Take the train from Buffalo Depew Station Amtrak to Chicago Union Station Amtrak
  2. Take the train from Chicago Union Station Amtrak to Ottumwa Amtrak
  3. Take the bus from Ottumwa, IA to Monroe, IA
  4. Take the bus from Monroe, IA to Des Moines, IA

$192 - $473

Train, bus Greyhound Canada  •  24 h 36 min

  1. Take the train from Buffalo to Toronto
  2. Take the bus from Toronto, ON to Chicago, IL
  3. Take the bus from Chicago, IL to Des Moines, IA

Drive  •  14 h 1 min

  1. Drive from Buffalo to Des Moines 855.7 miles

$80 - $130

Questions & Answers

The cheapest way to get from Buffalo to Des Moines is to drive which costs $80 - $130 and takes 14 h 1 min.

More details

The quickest way to get from Buffalo to Des Moines is to fly which costs $150 - $440 and takes 6 h 37 min.

More details

The distance between Buffalo and Des Moines is 762 miles. The road distance is 855.7 miles.

Get driving directions

It takes approximately 6 h 37 min to get from Buffalo to Des Moines, including transfers.

More details

No, there is no direct bus from Buffalo to Des Moines. However, there are services departing from Buffalo, Ny and arriving at Des Moines, IA via Cleveland, Oh, Clinton & Madison and Chicago, IL. The journey, including transfers, takes approximately 20 h 33 min.

More details

What companies run services between Buffalo, NY, USA and Des Moines, IA, USA?

United Airlines, American Airlines and Delta fly from Buffalo to Des Moines hourly. Alternatively, you can take a bus from Buffalo to Des Moines via Cleveland, Oh, Chicago Amtrak, Il, Clinton & Madison, Harrison & Jefferson, and Chicago, IL in around 20 h 33 min.

Airlines
American Airlines
Website
aa.com
Flights from Buffalo to Des Moines via Chicago O'Hare
Ave. Duration
4 h 53 min
When
Every day
Estimated price
$300 - $1,300
Flights from Buffalo to Des Moines via Philadelphia
Ave. Duration
6 h 10 min
When
Every day
Estimated price
$300 - $1,300
Flights from Buffalo to Des Moines via Charlotte
Ave. Duration
7 h 19 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$300 - $1,300
Flights from Buffalo to Des Moines via Dallas/Ft.Worth
Ave. Duration
7 h 26 min
When
Every day
Estimated price
$300 - $1,300
Flights from Buffalo to Des Moines via Reagan Washington
Ave. Duration
8 h 21 min
When
Every day
Estimated price
$300 - $1,300
Flights from Buffalo to Waterloo via Chicago O'Hare
Ave. Duration
5 h 2 min
When
Every day
Estimated price
$190 - $950
Flights from Buffalo to Waterloo via Reagan Washington, Chicago O'Hare
Ave. Duration
7 h 14 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$220 - $1,000
Flights from Buffalo to Waterloo via Philadelphia, Chicago O'Hare
Ave. Duration
7 h 48 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$230 - $1,000
Delta
Website
delta.com
Flights from Buffalo to Des Moines via Detroit
Ave. Duration
4 h 58 min
When
Every day
Estimated price
$420 - $900
Flights from Buffalo to Des Moines via Minneapolis
Ave. Duration
4 h 55 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$420 - $900
Flights from Buffalo to Des Moines via Atlanta
Ave. Duration
6 h 15 min
When
Every day
Estimated price
$420 - $900
Flights from Buffalo to Des Moines via New York La Guardia
Ave. Duration
7 h 29 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$420 - $900
United Airlines
Website
united.com
Flights from Buffalo to Des Moines via Chicago O'Hare
Ave. Duration
4 h 44 min
When
Every day
Estimated price
$310 - $1,200
Flights from Buffalo to Des Moines via Newark
Ave. Duration
8 h 23 min
When
Every day
Estimated price
$310 - $1,200
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Buffalo Depew Station Amtrak to Chicago Union Station Amtrak
Ave. Duration
10 h 31 min
Frequency
Twice daily
Estimated price
$75 - $220
Website
amtrak.com
Coach Seat
$75 - $120
Flexi Coach Seat
$140 - $200
Business Coach Seat
$150 - $220
Room
$330 - $460
Train from Chicago Union Station Amtrak to Ottumwa Amtrak
Ave. Duration
4 h 53 min
Frequency
Once daily
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Buffalo to Toronto
Ave. Duration
4 h 55 min
Frequency
Every 3 hours
Estimated price
$28 - $85
Website
viarail.ca
Escape
$28 - $40
Economy
$35 - $55
Economy Plus
$60 - $85
Business
$55 - $80
Business Plus/Sleeper
$100 - $150
Bus operators
Burlington Trailways
Website
burlingtontrailways.com
Bus from Waterloo, IA to Des Moines, IA
Ave. Duration
4 h 30 min
Frequency
Once daily
Estimated price
$40 - $60
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Chicago, IL to Des Moines, IA
Ave. Duration
6 h 50 min
Frequency
Every 3 hours
Estimated price
$45 - $80
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Ottumwa, IA to Monroe, IA
Ave. Duration
55 min
Frequency
Once a week
Estimated price
$25 - $40
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Monroe, IA to Des Moines, IA
Ave. Duration
45 min
Frequency
Once a week
Estimated price
$23 - $35
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Buffalo, Ny to Cleveland, Oh
Ave. Duration
3 h 15 min
Frequency
Hourly
Estimated price
$23 - $60
Website
greyhound.com
Economy
$23 - $40
Flexible
$40 - $60
Bus from Cleveland, Oh to Chicago Amtrak, Il
Ave. Duration
8 h 35 min
Frequency
Hourly
Estimated price
$40 - $100
Website
greyhound.com
Economy
$40 - $65
Flexible
$75 - $100
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from Toronto, ON to Chicago, IL
Ave. Duration
10 h 45 min
Frequency
4 times a day
Estimated price
$45 - $120
Website
Greyhound.ca
Advanced Purchase
$45 - $70
Online Fare
$60 - $90
Standard Fare
$75 - $120
Refundable
$85 - $130
Windstar
Phone
+1 888-494-6378
Email
sara@gowindstar.com
Website
gowindstar.com
Bus from Chicago, IL to Des Moines, IA
Ave. Duration
6 h 40 min
Frequency
Once daily
Schedules at
gowindstar.com

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