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How to get fromBuffalo to Des Moinesby plane, train, bus, bus (Greyhound) or car

Find Transport to Des Moines

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There are 6 ways to get from Buffalo to Des Moines by plane, train, bus, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Des Moines

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Des Moines (DSM)plane plane BUF - DSM
    5h 58m
    $271–1,501

  2. Bus

    cheapest
    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    19h 39m
    $96–244

  3. Train, bus

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123 / ...
    19h 33m
    $114–394

  4. Drive 847.2 mi

    1. Drive from Buffalo to Des Moinescar car 847.2 mi
    14h 14m
    $155–224

  5. Bus to Rochester, fly to Des Moines

    1. Take the bus from Buffalo, NY to Rochester, NYbus bus
    2. Fly from Rochester (ROC) to Des Moines (DSM)plane plane ROC - DSM
    8h 6m
    $251–1,356

  6. Fly Buffalo Niagara International Airport to Fort Dodge Municipal Airport, drive

    1. Fly from Buffalo Niagara International Airport (BUF) to Fort Dodge Municipal Airport (FOD)plane plane BUF - FOD
    2. Drive from Fort Dodge Municipal Airport (FOD) to Des Moinescar car
    9h 42m
    $140–805

Buffalo to Des Moines by train, foot, and bus

Calendar14Weekly Services
Duration19h 33mAverage Duration
Ticket$114Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Des Moines, IA, USA?

Delta, American Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Des Moines (DSM) every 3 hours. Alternatively, you can take a bus from Buffalo to Des Moines via Cleveland Bus Station and Chicago Bus Station in around 19h 39m.

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