There are 6 ways to get from Buffalo to Clemson by plane, taxi, train (Amtrak), bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Greenville–Spartanburg International Airport, taxi
best- Fly from Buffalo Niagara International Airport (BUF) to Greenville–Spartanburg International Airport (GSP)plane BUF - GSP
- Take the taxi from Greenville–Spartanburg International Airport (GSP) to Clemsontaxi
6h 1m$11,156–14,928Fly to Asheville Regional Airport, drive
cheapest- Fly from Buffalo Niagara International Airport (BUF) to Asheville Regional Airport (AVL)plane BUF - AVL
- Drive from Asheville-Airport-AVL to Clemsoncar
6h 57m$129–697Train (Amtrak)
- Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain Empire Service / ...
- Take the train from Ny Moynihan Train Hall At Penn Station to Clemson Amtrak Stationtrain Crescent
25h 34m$293–667Bus, taxi
- Take the bus from Buffalo to Cleveland Bus Stationbus
- Take the bus from Cleveland Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus
- Take the taxi from Taqueria Guadalajara - Greenville to Clemsontaxi
30h 51m$7,714–9,965Drive 753.8 mi
- Drive from Buffalo to Clemsoncar 753.8 mi
13h 34m$138–199Bus, train
- Take the bus from Buffalo to New York Midtownbus FlixBus 2686 / ...
- Take the train from Ny Moynihan Train Hall At Penn Station to Clemson Amtrak Stationtrain Crescent
25h 37m$236–515
Buffalo to Clemson by train (Amtrak)
Questions & Answers
The cheapest way to get from Buffalo to Clemson is to drive which costs $130 - $200 and takes 13h 34m.
The fastest way to get from Buffalo to Clemson is to fly and taxi which takes 6h 1m and costs $11,000 - $15,000.
No, there is no direct train from Buffalo to Clemson station. However, there are services departing from Buffalo and arriving at Clemson Amtrak Station via Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 25h 34m.
The distance between Buffalo and Clemson is 643 miles. The road distance is 758.2 miles.
The best way to get from Buffalo to Clemson without a car is to train which takes 25h 34m and costs $290 - $700.
It takes approximately 6h 1m to get from Buffalo to Clemson, including transfers.
Buffalo to Clemson train services, operated by Amtrak, depart from Buffalo station.
Buffalo to Clemson train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Buffalo to Clemson is 758 miles. It takes approximately 13h 34m to drive from Buffalo to Clemson.
Book your Buffalo to Clemson train tickets online with Omio.
What companies run services between Buffalo, NY, USA and Clemson, SC, USA?
You can take a train from Buffalo to Clemson Amtrak Station via Ny Moynihan Train Hall At Penn Station in around 25h 34m.
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Greenville–Spartanburg International Airport via Philadelphia
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $170–950
Flights from Buffalo Niagara International Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 59m
- When
- Every day
- Estimated price
- $150–900
Flights from Buffalo Niagara International Airport to Greenville–Spartanburg International Airport via Reagan Washington
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $160–900
Flights from Buffalo Niagara International Airport to Asheville Regional Airport via Charlotte
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $110–650
Flights from Buffalo Niagara International Airport to Asheville Regional Airport via Reagan Washington
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $110–650
Flights from Buffalo Niagara International Airport to Asheville Regional Airport via Philadelphia
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $120–700
Flights from Buffalo Niagara International Airport to Asheville Regional Airport via New York La Guardia
- Ave. Duration
- 5h 27m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–750
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Greenville–Spartanburg International Airport via Detroit
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $160–950
Flights from Buffalo Niagara International Airport to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $180–1,000
Flights from Buffalo Niagara International Airport to Asheville Regional Airport via Atlanta
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $130–750
Flights from Buffalo Niagara International Airport to Asheville Regional Airport via New York La Guardia
- Ave. Duration
- 4h 44m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–750
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Greenville–Spartanburg International Airport via Baltimore
- Ave. Duration
- 3h 52m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $160–950
Flights from Buffalo Niagara International Airport to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 4h 45m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $180–1,000
- Website
- united.com
Flights from Buffalo Niagara International Airport to Greenville–Spartanburg International Airport via Washington Dulles
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $150–900
Flights from Buffalo Niagara International Airport to Asheville Regional Airport via Newark
- Ave. Duration
- 4h 43m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–750
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 8h 27m
- Frequency
- 3 times a day
- Estimated price
- $110–250
- Website
- https://www.amtrak.com/home.html
Train from Ny Moynihan Train Hall At Penn Station to Clemson Amtrak Station
- Ave. Duration
- 16h 7m
- Frequency
- Once daily
- Estimated price
- $180–420
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Buffalo to Cleveland Bus Station
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $30–60
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Atlanta Bus Station
- Ave. Duration
- 20h
- Frequency
- Once daily
- Estimated price
- $130–250
- Website
- https://www.greyhound.com/
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Atlanta to Taqueria Guadalajara - Greenville
- Ave. Duration
- 3h 22m
- Frequency
- Once daily
- Estimated price
- $45–150
- Schedules at
- tornadobus.com
- Adults 11-59
- $45–150
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Buffalo to New York Midtown
- Ave. Duration
- 8h 30m
- Frequency
- Every 3 hours
- Estimated price
- $55–100
- Schedules at
- flixbus.com
- Ave. Duration
- 46 min
- Estimated price
- $7,500–14,000
Yellow Cab Greenville
- Phone
- +1 864-233-6666
- Website
- yellowcabgreenville.com
Checker Cab
- Phone
- +1 864-583-2721
Yellow Cab Greenville
- Phone
- +1 864-233-6666
- Website
- yellowcabgreenville.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 105+ hotels available in Clemson.










