Rome2Rio

How to get fromBuffalo to Clemsonby plane, taxi, bus (Flixbus), bus, train, car or train (Amtrak)

Find Transport to Clemson

See all options

There are 6 ways to get from Buffalo to Clemson by plane, taxi, bus (Flixbus), bus, train, car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Greenville–Spartanburg International Airport, taxi

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Greenville–Spartanburg International Airport (GSP)planeBUF - GSP
    2. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Clemsontaxi
    6h 1m
    $254–1,060

  2. Bus, train

    cheapest
    1. Take the bus from Buffalo to NewarkbusAdt N813 / ...
    2. Take the train from Newark Penn Station to Clemson Amtrak StationtrainCrescent
    24h 12m
    $123–334

  3. Bus

    1. Take the bus from Buffalo to New York MidtownbusFlixBus N2686 / ...
    2. Take the bus from New York to Anderson, SCbusNyc
    23h 32m
    $183–282

  4. Drive 753.8 mi

    1. Drive from Buffalo to Clemsoncar753.8 mi
    13h 27m
    $138–199

  5. Fly to Asheville Regional Airport, drive

    1. Fly from Buffalo Niagara International Airport (BUF) to Asheville Regional Airport (AVL)planeBUF - AVL
    2. Drive from Asheville-Airport-AVL to Clemsoncar
    7h
    $127–749

  6. Train (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn StationtrainEmpire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Clemson Amtrak StationtrainCrescent
    25h 34m
    $305–1,155

Buffalo to Clemson by bus and train

Calendar7Weekly Services
Duration24h 12mAverage Duration
Ticket$123Cheapest Price
See schedules

Questions & Answers

What companies run services between Buffalo, NY, USA and Clemson, SC, USA?

You can take a bus from Buffalo to Clemson via New York Midtown, 34 St-Herald Sq, Canal St, New York, and Anderson, SC in around 23h 32m. Alternatively, you can take a train from Buffalo to Clemson Amtrak Station via Ny Moynihan Train Hall At Penn Station in around 25h 34m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

More Questions & Answers

Trips from Buffalo

Trips to Clemson

Popular routes