There are 6 ways to get from Buffalo to Chicago Loop by plane, train (Amtrak), bus (Greyhound), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Buffalo Niagara International Airport to Chicago Midway International Airport
best- Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane BUF - MDW
3h 35m$108–683Fly Buffalo Niagara International Airport to Chicago O'Hare International Airport
cheapest- Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane BUF - ORD
3h 51m$83–503Train (Amtrak)
- Take the train from Buffalo Depew Station to Chicago Union Stationtrain Lake Shore Limited
11h 50m$149–395Bus (Greyhound)
- Take the bus from Buffalo to Cleveland Bus Stationbus Greyhound US0171 / ...
- Take the bus from Cleveland Bus Station to Chicago Bus Stationbus Greyhound US0164
12h 9m$91–176Drive 531.7 mi
- Drive from Buffalo to Chicago Loopcar 531.7 mi
9h 4m$97–141Bus to Rochester, fly to Chicago Midway International Airport
- Take the bus from Buffalo to Rochester Bus Stopbus
- Fly from Rochester (ROC) to Chicago Midway International Airport (MDW)plane ROC - MDW
5h 15m$120–602
Buffalo to Chicago Loop by train (Amtrak)
Questions & Answers
The cheapest way to get from Buffalo to Chicago Loop is to bus which costs $90 - $180 and takes 12h 9m.
The fastest way to get from Buffalo to Chicago Loop is to fly which takes 3h 35m and costs $100 - $700.
No, there is no direct bus from Buffalo to Chicago Loop. However, there are services departing from Buffalo and arriving at Washington & Lasalle via Cleveland Bus Station and Jefferson & Harrison. The journey, including transfers, takes approximately 12h 9m.
No, there is no direct train from Buffalo to Chicago Loop station. However, there are services departing from Buffalo and arriving at Chicago Union Station via Buffalo Depew Station. The journey, including transfers, takes approximately 11h 50m.
The distance between Buffalo and Chicago Loop is 492 miles. The road distance is 534.8 miles.
The best way to get from Buffalo to Chicago Loop without a car is to train which takes 11h 50m and costs $140 - $400.
It takes approximately 3h 35m to get from Buffalo to Chicago Loop, including transfers.
Buffalo to Chicago Loop bus services, operated by Greyhound USA, depart from Buffalo station.
Buffalo to Chicago Loop train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from Buffalo to Chicago Loop is to fly which takes 3h 35m and costs $100 - $700. Alternatively, you can train, which costs $140 - $400 and takes 11h 50m, you could also bus, which costs $90 - $180 and takes 12h 9m.
What companies run services between Buffalo, NY, USA and Chicago Loop, IL, USA?
Southwest Airlines and Delta fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW) 4 times a day. Alternatively, Amtrak operates a train from Buffalo Depew Station to Chicago Union Station twice daily. Tickets cost $140–320 and the journey takes 10h 33m.
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $100–650
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport via Baltimore
- Ave. Duration
- 4h 10m
- When
- Monday, Thursday, and Friday
- Estimated price
- $160–850
Flights from Rochester to Chicago Midway International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $90–550
Flights from Rochester to Chicago Midway International Airport via Baltimore
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $130–650
- Website
- united.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 59m
- When
- Every day
- Estimated price
- $75–470
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $110–600
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 8m
- When
- Every day
- Estimated price
- $75–470
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport via Reagan Washington
- Ave. Duration
- 4h 49m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport via Detroit
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- $100–650
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo Depew Station to Chicago Union Station
- Ave. Duration
- 10h 33m
- Frequency
- Twice daily
- Estimated price
- $140–320
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Buffalo to Cleveland Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Chicago Bus Station
- Ave. Duration
- 7h 40m
- Frequency
- Twice daily
- Estimated price
- $55–110
- Website
- https://www.greyhound.com/
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $12–24
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- Every 3 hours
- Estimated price
- $9–17
- Schedules at
- flixbus.com
Want to know more about travelling around United States
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More Questions & Answers
Buffalo to Chicago Loop bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Chicago Loop is 1h behind Buffalo. It is currently 4:05 PM in Buffalo and 3:05 PM in Chicago Loop.
Buffalo to Chicago Loop train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Buffalo to Chicago Loop is 535 miles. It takes approximately 9h 4m to drive from Buffalo to Chicago Loop.
Book your Buffalo to Chicago Loop train tickets online with Omio.
There are 2056+ hotels available in Chicago Loop.