There are 6 ways to get from Buffalo to Chicago Loop by plane, train (Amtrak), bus (Greyhound), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Buffalo Niagara International Airport to Chicago Midway International Airport
best- Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)BUF - MDW
4h$104–607Bus
cheapest- Take the bus from Buffalo to Cleveland Bus StationGreyhound US0170
- Take the bus from Cleveland Bus Station to Chicago Bus StationGreyhound US0164
12h 19m$59–124Train (Amtrak)
- Take the train from Buffalo Depew Station to Chicago Union StationLake Shore Limited
11h 50m$89–262Drive 532.4 mi
- Drive from Buffalo to Chicago Loop532.4 mi
8h 56m$98–141Fly Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)BUF - ORD
4h 14m$74–437Bus to Rochester, fly to Chicago O'Hare International Airport
- Take the bus from Buffalo, NY to Rochester, NY
- Fly from Rochester (ROC) to Chicago O'Hare International Airport (ORD)ROC - ORD
6h 9m$136–600
Buffalo to Chicago Loop by train (Amtrak)
Questions & Answers
The cheapest way to get from Buffalo to Chicago Loop is to bus which costs $55 - $130 and takes 12h 19m.
The fastest way to get from Buffalo to Chicago Loop is to fly which takes 4h and costs $100 - $650.
No, there is no direct bus from Buffalo to Chicago Loop. However, there are services departing from Buffalo and arriving at Washington & Lasalle via Cleveland Bus Station and Jefferson & Harrison. The journey, including transfers, takes approximately 12h 19m.
No, there is no direct train from Buffalo to Chicago Loop station. However, there are services departing from Buffalo and arriving at Chicago Union Station via Buffalo Depew Station. The journey, including transfers, takes approximately 11h 50m.
The distance between Buffalo and Chicago Loop is 493 miles. The road distance is 535.5 miles.
The best way to get from Buffalo to Chicago Loop without a car is to train which takes 11h 50m and costs $85 - $270.
It takes approximately 4h to get from Buffalo to Chicago Loop, including transfers.
Buffalo to Chicago Loop bus services, operated by Greyhound USA, depart from Buffalo station.
Buffalo to Chicago Loop train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from Buffalo to Chicago Loop is to fly which takes 4h and costs $100 - $650. Alternatively, you can train, which costs $85 - $270 and takes 11h 50m, you could also bus, which costs $55 - $130 and takes 12h 19m.
What companies run services between Buffalo, NY, USA and Chicago Loop, IL, USA?
Southwest Airlines and Delta fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW) 4 times a day. Alternatively, Amtrak operates a train from Buffalo Depew Station to Chicago Union Station twice daily. Tickets cost $80–190 and the journey takes 10h 33m.
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- Website
- united.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 3m
- When
- Every day
- Estimated price
- $70–430
Flights from Rochester to Chicago O'Hare International Airport
- Ave. Duration
- 2h 13m
- When
- Every day
- Estimated price
- $60–370
Flights from Rochester to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 31m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–430
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 6m
- When
- Every day
- Estimated price
- $70–430
Flights from Rochester to Chicago O'Hare International Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- $60–370
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport via Detroit
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $100–600
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $70–430
Flights from Rochester to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 4h 8m
- When
- Thursday and Saturday
- Estimated price
- $60–370
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 51m
- When
- Every day
- Estimated price
- $100–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo Depew Station to Chicago Union Station
- Ave. Duration
- 10h 33m
- Frequency
- Twice daily
- Estimated price
- $80–190
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Buffalo to Cleveland Bus Station
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Estimated price
- $25–45
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Chicago Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- Twice daily
- Estimated price
- $40–70
- Website
- https://www.greyhound.com/
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Cleveland Bus Station to Chicago Bus Station
- Ave. Duration
- 7h 35m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- https://baronsbus.com
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Buffalo, NY to Rochester, NY
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $20–55
- Website
- https://www.ourbus.com
Want to know more about travelling around United States
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More Questions & Answers
Buffalo to Chicago Loop bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Chicago Loop is 1h behind Buffalo. It is currently 7:10 PM in Buffalo and 6:10 PM in Chicago Loop.
Buffalo to Chicago Loop train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Buffalo to Chicago Loop is 536 miles. It takes approximately 8h 56m to drive from Buffalo to Chicago Loop.
Book your Buffalo to Chicago Loop train tickets online with Omio.
There are 1138+ hotels available in Chicago Loop.