There are 5 ways to get from Buffalo to Chicago, IL by plane, train (Amtrak), bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Chicago O'Hare International Airport
best- Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)BUF - ORD
4h 8m$81–535Bus
cheapest- Take the bus from Buffalo to Cleveland Bus StationGreyhound US0170
- Take the bus from Cleveland Bus Station to Chicago Bus StationGreyhound US0164
12h 5m$58–147Train (Amtrak)
- Take the train from Buffalo Depew Station to Chicago Union StationLake Shore Limited
11h 59m$74–274Drive 532.1 mi
- Drive from Buffalo to Chicago, IL532.1 mi
8h 56m$98–141Fly to Chicago Midway International Airport
- Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)BUF - MDW
3h 57m$106–685
Buffalo to Chicago, IL by train and foot (Amtrak)
Questions & Answers
The cheapest way to get from Buffalo to Chicago, IL is to bus which costs $55 - $150 and takes 12h 5m.
The fastest way to get from Buffalo to Chicago, IL is to fly which takes 3h 57m and costs $100 - $700.
No, there is no direct bus from Buffalo to Chicago, IL station. However, there are services departing from Buffalo and arriving at Chicago Bus Station via Cleveland Bus Station. The journey, including transfers, takes approximately 12h 5m.
No, there is no direct train from Buffalo to Chicago, IL station. However, there are services departing from Buffalo and arriving at Chicago Union Station via Buffalo Depew Station. The journey, including transfers, takes approximately 11h 59m.
The distance between Buffalo and Chicago, IL is 504 miles. The road distance is 535.2 miles.
The best way to get from Buffalo to Chicago, IL without a car is to train which takes 11h 59m and costs $70 - $280.
It takes approximately 4h 8m to get from Buffalo to Chicago, IL, including transfers.
Buffalo to Chicago, IL bus services, operated by Greyhound USA, depart from Buffalo station.
Buffalo to Chicago, IL train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from Buffalo to Chicago, IL is to fly which takes 4h 8m and costs $80 - $550. Alternatively, you can train, which costs $70 - $280 and takes 11h 59m, you could also bus, which costs $55 - $150 and takes 12h 5m.
What companies run services between Buffalo, NY, USA and Chicago, IL, USA?
American Airlines, United Airlines, and Delta fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD) every 2 hours. Alternatively, Amtrak operates a train from Buffalo Depew Station to Chicago Union Station twice daily. Tickets cost $65–200 and the journey takes 10h 33m.
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- $75–450
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- $100–600
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport via Baltimore
- Ave. Duration
- 4h 21m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- $140–750
- Website
- united.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 8m
- When
- Every day
- Estimated price
- $75–450
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- $75–450
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport via Detroit
- Ave. Duration
- 3h 39m
- When
- Every day
- Estimated price
- $100–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo Depew Station to Chicago Union Station
- Ave. Duration
- 10h 33m
- Frequency
- Twice daily
- Estimated price
- $65–200
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Buffalo to Cleveland Bus Station
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Estimated price
- $27–60
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Chicago Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- Twice daily
- Estimated price
- $40–90
- Website
- https://www.greyhound.com/
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Cleveland Bus Station to Chicago Bus Station
- Ave. Duration
- 7h 35m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- https://baronsbus.com
Want to know more about travelling around United States
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More Questions & Answers
Buffalo to Chicago, IL bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Chicago, IL is 1h behind Buffalo. It is currently 6:38 PM in Buffalo and 5:38 PM in Chicago, IL.
Buffalo to Chicago, IL train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Buffalo to Chicago, IL is 535 miles. It takes approximately 8h 56m to drive from Buffalo to Chicago, IL.
Book your Buffalo to Chicago, IL train tickets online with Omio.
Book your Buffalo to Chicago, IL bus tickets online with Omio and FlixBus.
There are 1243+ hotels available in Chicago, IL.