There are 7 ways to get from Buffalo to Chicago by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Buffalo to Chicago O'Hare  •  3 h 38 min

  1. Fly from Buffalo (BUF) to Chicago O'Hare (ORD) BUF - ORD

$130 - $391

Cheapest option

Bus  •  15 h 25 min

  1. Take the bus from Buffalo, Ny to Toronto, On 300 / ...
  2. Take the bus from Toronto, On to Chicago, Il 5515

$61 - $176

5 alternative options

Fly Buffalo to Chicago Midway  •  3 h 25 min

  1. Fly from Buffalo (BUF) to Chicago Midway (MDW) BUF - MDW

$140 - $420

Bus to Erie, fly to Chicago O'Hare  •  5 h 31 min

  1. Take the bus from Buffalo, Ny to Erie, Pa
  2. Fly from Erie (ERI) to Chicago O'Hare (ORD) ERI - ORD

$187 - $880

Train  •  11 h 45 min

  1. Take the train from Buffalo Depew Station Amtrak to Chicago Union Station Amtrak Lake Shore Limited

$94 - $268

Train, bus  •  17 h 39 min

  1. Take the train from Buffalo to Toronto VIA Rail
  2. Take the bus from Toronto, ON to Chicago - Amtrak 5531

$76 - $196

Drive  •  8 h 55 min

  1. Drive from Buffalo to Chicago 535.9 miles

$50 - $80

Questions & Answers

The cheapest way to get from Buffalo to Chicago is to drive which costs $50 - $80 and takes 8 h 55 min.

More details

The quickest way to get from Buffalo to Chicago is to fly which takes 3 h 25 min and costs $140 - $420.

More details

The distance between Buffalo and Chicago is 727 km. The road distance is 857 km.

Get driving directions

It takes approximately 3 h 38 min to get from Buffalo to Chicago, including transfers.

More details

No, there is no direct bus from Buffalo to Chicago. However, there are services departing from Buffalo, Ny and arriving at Chicago, Il via Toronto, On. The journey, including transfers, takes approximately 15 h 25 min.

More details

No, there is no direct train from Buffalo to Chicago. However, there are services departing from Buffalo and arriving at Chicago Union Station Amtrak via Buffalo Depew Station Amtrak. The journey, including transfers, takes approximately 11 h 45 min.

More details

What companies run services between Buffalo, NY, USA and Chicago, IL, USA?

United Airlines, American Airlines and Delta fly from Buffalo to Chicago hourly. Alternatively, Amtrak operates a train from Buffalo to Chicago twice daily. Tickets cost $75 - $220 and the journey takes 10 h 31 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Buffalo to Chicago Midway
Ave. Duration
1 h 38 min
When
Every day
Estimated price
$160 - $750
United Airlines
Website
united.com
Flights from Buffalo to Chicago O'Hare
Ave. Duration
1 h 47 min
When
Every day
Estimated price
$140 - $750
Flights from Buffalo to Chicago O'Hare via Washington Dulles
Ave. Duration
4 h 9 min
When
Every day
Estimated price
$140 - $750
Flights from Erie to Chicago O'Hare
Ave. Duration
1 h 39 min
When
Every day
Estimated price
$170 - $850
American Airlines
Website
aa.com
Flights from Buffalo to Chicago O'Hare
Ave. Duration
1 h 50 min
When
Every day
Estimated price
$120 - $650
Delta
Website
delta.com
Flights from Buffalo to Chicago O'Hare via Detroit
Ave. Duration
3 h 39 min
When
Every day
Estimated price
$130 - $800
Flights from Buffalo to Chicago Midway via Detroit
Ave. Duration
3 h 33 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$130 - $800
Flights from Erie to Chicago O'Hare via Detroit
Ave. Duration
3 h 35 min
When
Every day
Estimated price
$140 - $800
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Buffalo Depew Station Amtrak to Chicago Union Station Amtrak
Ave. Duration
10 h 31 min
Frequency
Twice daily
Estimated price
$75 - $220
Website
amtrak.com
Coach Seat
$75 - $120
Flexi Coach Seat
$140 - $200
Business Coach Seat
$150 - $220
Room
$330 - $460
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Buffalo to Toronto
Ave. Duration
4 h 55 min
Frequency
Every 3 hours
Estimated price
$28 - $85
Website
viarail.ca
Escape
$28 - $40
Economy
$35 - $55
Economy Plus
$60 - $85
Business
$55 - $80
Business Plus/Sleeper
$100 - $140
Bus operators
Greyhound USA
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Buffalo, Ny to Erie, Pa
Ave. Duration
1 h 55 min
Frequency
Every 30 minutes
Estimated price
$15 - $35
Website
greyhound.com
Economy
$15 - $23
Flexible
$27 - $35
Bus from Buffalo, Ny to Toronto, On
Ave. Duration
2 h 45 min
Frequency
Hourly
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $24
Flexible
$28 - $40
Bus from Toronto, On to Chicago, Il
Ave. Duration
11 h 45 min
Frequency
Hourly
Estimated price
$50 - $140
Website
greyhound.com
Economy
$50 - $85
Flexible
$100 - $140
Megabus CA
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from Toronto, ON to Chicago - Amtrak
Ave. Duration
11 h 35 min
Frequency
Once daily
Estimated price
$45 - $110
Website
Greyhound.ca
Advanced Purchase
$45 - $65
Online Fare
$60 - $90
Standard Fare
$75 - $110
Refundable
$85 - $120

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