There are 6 ways to get from Buffalo to Boston by bus (Greyhound), train (Amtrak), car, plane, train, bus (Flixbus), or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from Buffalo to Bostonbus Greyhound US0171
10h 5m$80–130Train (Amtrak)
- Take the train from Buffalo Depew Station to Bostontrain Lake Shore Limited
12h 44m$272–554Drive 454.3 mi
- Drive from Buffalo to Bostoncar 454.3 mi
7h 58m$83–120Fly to Laguardia Airport, train
- Fly from Buffalo Niagara International Airport (BUF) to Laguardia Airport (LGA)plane BUF - LGA
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
8h 8m$195–688Bus via Ithaca (Flixbus)
- Take the bus from Buffalo to Ithacabus FlixBus 2685 / ...
- Take the bus from Ithaca to Bostonbus FlixBus 2691
12h 40m$80–127Fly to Provincetown Municipal Airport, ferry
- Fly from Buffalo Niagara International Airport (BUF) to Provincetown Municipal Airport (PVC)plane BUF - PVC
- Take the ferry from MacMillan Pier, Provincetown, MA to World Trade Center Pier, Boston, MAferry
7h 52m$158–542
Buffalo to Boston by bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Buffalo to Boston is to bus which costs $80 - $130 and takes 10h 5m.
The fastest way to get from Buffalo to Boston is to fly and ferry which takes 7h 52m and costs $150 - $550.
Yes, there is a direct bus departing from Buffalo and arriving at Boston. Services depart once daily, and operate every day. The journey takes approximately 10h 5m.
No, there is no direct train from Buffalo to Boston. However, there are services departing from Buffalo and arriving at Boston via Buffalo Depew Station. The journey, including transfers, takes approximately 12h 44m.
The distance between Buffalo and Boston is 472 miles. The road distance is 456.9 miles.
The best way to get from Buffalo to Boston without a car is to bus which takes 10h 5m and costs $80 - $130.
The bus from Buffalo to Boston takes 10h 5m including transfers and departs once daily.
Buffalo to Boston bus services, operated by Greyhound USA, depart from Buffalo station.
Buffalo to Boston train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from Buffalo to Boston is to bus which takes 10h 5m and costs $80 - $130. Alternatively, you can train, which costs $270 - $600 and takes 12h 44m.
What companies run services between Buffalo, NY, USA and Boston, MA, USA?
Greyhound USA operates a bus from Buffalo to Boston once daily. Tickets cost $80–130 and the journey takes 10h 5m. Alternatively, Amtrak operates a train from Buffalo Depew Station to Boston once daily. Tickets cost $270–420 and the journey takes 11h 27m.
- Website
- capeair.com
Flights from Buffalo Niagara International Airport to Provincetown Municipal Airport via Boston
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $70–430
Flights from Buffalo Niagara International Airport to Provincetown Municipal Airport via Washington Dulles, Boston
- Ave. Duration
- 6h 37m
- When
- Thursday and Tuesday
- Estimated price
- $90–500
Flights from Buffalo Niagara International Airport to Provincetown Municipal Airport via Laguardia Airport, Boston
- Ave. Duration
- 6h 35m
- When
- Thursday to Friday
- Estimated price
- $75–450
Flights from Buffalo Niagara International Airport to Provincetown Municipal Airport via Newark, Boston
- Ave. Duration
- 6h 40m
- When
- Every day
- Estimated price
- $75–450
Flights from Buffalo Niagara International Airport to Provincetown Municipal Airport via New York JFK, Boston
- Ave. Duration
- 6h 11m
- When
- Every day
- Estimated price
- $75–450
Flights from Buffalo Niagara International Airport to Provincetown Municipal Airport via Reagan Washington, Boston
- Ave. Duration
- 6h 44m
- When
- Every day
- Estimated price
- $90–500
Flights from Buffalo Niagara International Airport to Provincetown Municipal Airport via Baltimore, Boston
- Ave. Duration
- 6h 39m
- When
- Sunday, Tuesday, and Wednesday
- Estimated price
- $90–490
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Laguardia Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $70–480
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Laguardia Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $70–480
- Website
- united.com
Flights from Buffalo Niagara International Airport to Laguardia Airport via Washington Dulles
- Ave. Duration
- 3h 34m
- When
- Every day
- Estimated price
- $90–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Buffalo Depew Station to Boston
- Ave. Duration
- 11h 27m
- Frequency
- Once daily
- Estimated price
- $270–420
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 4h 21m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 3h 47m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Buffalo to Boston
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $80–130
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Buffalo to Ithaca
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- $25–40
- Schedules at
- Flixbus USA
Bus from Ithaca to Boston
- Ave. Duration
- 7h 55m
- Frequency
- 3 times a week
- Estimated price
- $55–90
- Schedules at
- Flixbus USA
- Phone
- +1 617-748-1428
- Website
- Provincetown Fast Ferry
Ferry from MacMillan Pier, Provincetown, MA to World Trade Center Pier, Boston, MA
- Ave. Duration
- 1h 35m
- Frequency
- 3 times a day
- Estimated price
- $87
- Website
- Provincetown Fast Ferry
- Phone
- +1 866-307-2469
- Website
- City Experiences
Ferry from MacMillan Pier, Provincetown, MA to World Trade Center Pier, Boston, MA
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $72
- Website
- City Experiences
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Booking & Getting There
Buffalo to Boston bus services, operated by Greyhound USA, arrive at Boston station.
Buffalo to Boston train services, operated by Amtrak, arrive at Boston station.
Yes, the driving distance between Buffalo to Boston is 457 miles. It takes approximately 7h 58m to drive from Buffalo to Boston.
Book your Buffalo to Boston train tickets online with Omio.
Book your Buffalo to Boston bus tickets online with Omio and FlixBus.
There are 1662+ hotels available in Boston.









