There are 6 ways to get from Buffalo–Depew Station to Worcester by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Buffalo to Boston, bus  •  4 h 29 min

  1. Fly from Buffalo (BUF) to Boston (BOS) BUF - BOS
  2. Take the bus from Boston, Ma to Worcester, Ma

$111 - $428

Cheapest option

Train  •  9 h 53 min

  1. Take the train from Buffalo Depew Station Amtrak to Worcester Amtrak Lake Shore Limited

$70 - $190

4 alternative options

Fly Buffalo to Worcester  •  7 h 24 min

  1. Fly from Buffalo (BUF) to Worcester (ORH) BUF - ORH

$135 - $670

Train to Rochester, fly to Boston, bus  •  5 h 46 min

  1. Take the train from Buffalo to Rochester
  2. Fly from Rochester (ROC) to Boston (BOS) ROC - BOS
  3. Take the bus from Boston, Ma to Worcester, Ma

$158 - $539

Bus  •  11 h 21 min

  1. Take the bus from Buffalo, NY to Albany, NY Buffalo
  2. Take the bus from Albany, Ny to Worcester, Ma 255 / ...

$70 - $121

Drive  •  7 h 1 min

  1. Drive from Buffalo–Depew Station to Worcester 411 miles

$40 - $60

Questions & Answers

No, there is no direct bus from Buffalo–Depew Station station to Worcester. However, there are services departing from Amtrak Station & Dick Rd and arriving at Worcester, Ma via Walden Ave & Thruway Transit Center, Buffalo, NY, Albany Bus Terminal and Albany, Ny. The journey, including transfers, takes approximately 11 h 21 min.

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Yes, there is a direct train departing from Buffalo Depew Station Amtrak station and arriving at Worcester Amtrak. Services depart once daily, and operate every day. The journey takes approximately 9 h 53 min.

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The distance between Buffalo–Depew Station and Worcester is 357 miles. The road distance is 411 miles.

Get driving directions

The best way to get from Buffalo–Depew Station to Worcester without a car is to train which takes 9 h 53 min and costs .

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It takes approximately 4 h 29 min to get from Buffalo–Depew Station to Worcester, including transfers.

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Buffalo–Depew Station to Worcester bus services, operated by Trailways New York, depart from Buffalo, NY station.

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Buffalo–Depew Station to Worcester train services, operated by Amtrak, arrive at Buffalo Depew Station Amtrak.

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The best way to get from Buffalo–Depew Station to Worcester is to fly which takes 7 h 24 min and costs . Alternatively, you can train, which costs and takes 9 h 53 min, you could also bus, which costs and takes 11 h 21 min.

Mode details

The quickest flight from Buffalo Airport to Boston Airport is the direct flight which takes 1 h 18 min.

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Buffalo–Depew Station to Worcester bus services, operated by Greyhound USA, arrive at Worcester, Ma station.

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Map of how to get from Buffalo–Depew Station to Worcester.
Launch map view
  • Distance: 357 miles
  • Duration: 4 h 29 min

What companies run services between Buffalo–Depew Station, NY, USA and Worcester, MA, USA?

American Airlines, JetBlue Airways and Delta fly from Buffalo–Depew Station to Worcester every 4 hours. Alternatively, Amtrak operates a train from Buffalo–Depew Station to Worcester once daily. Tickets cost $70 - $190 and the journey takes 9 h 53 min.

Airlines
JetBlue Airways
Website
jetblue.com
Flights from Buffalo to Boston
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$100 - $550
Flights from Buffalo to Worcester via New York JFK
Ave. Duration
7 h 2 min
When
Every day
Estimated price
$110 - $600
Flights from Buffalo to Worcester via Fort Lauderdale
Ave. Duration
8 h 48 min
When
Every day
Estimated price
$230 - $950
American Airlines
Website
aa.com
Flights from Buffalo to Worcester via Philadelphia
Ave. Duration
5 h 38 min
When
Every day
Estimated price
$130 - $650
Flights from Rochester to Boston
Ave. Duration
1 h 21 min
When
Every day
Estimated price
$150 - $700
Delta
Website
delta.com
Flights from Buffalo to Boston
Ave. Duration
1 h 32 min
When
Every day
Estimated price
$130 - $750
United Airlines
Website
united.com
Flights from Buffalo to Boston via Newark
Ave. Duration
3 h 30 min
When
Every day
Estimated price
$170 - $900
Flights from Rochester to Boston via Newark
Ave. Duration
3 h 16 min
When
Every day
Estimated price
$180 - $850
Southwest Airlines
Website
southwest.com
Flights from Buffalo to Boston via Baltimore
Ave. Duration
3 h 30 min
When
Saturday
Estimated price
$220 - $800
Flights from Rochester to Boston via Baltimore
Ave. Duration
3 h 35 min
When
Monday to Saturday
Estimated price
$250 - $750
Air Canada
Website
aircanada.com
Flights from Rochester to Boston via Toronto
Ave. Duration
3 h 32 min
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$140 - $600
Train operators
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Buffalo to Rochester
Ave. Duration
54 min
Frequency
Every 3 hours
Estimated price
$24 - $70
Website
viarail.ca
Escape
$24 - $35
Economy
$30 - $45
Economy Plus
$50 - $70
Business
$40 - $60
Business Plus/Sleeper
$75 - $110
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Buffalo Depew Station Amtrak to Rochester Amtrak
Ave. Duration
54 min
Frequency
5 times a day
Estimated price
$25 - $50
Website
amtrak.com
Coach Seat
$25 - $40
Flexi Coach Seat
$45 - $65
Business Coach Seat
$35 - $50
Room
$140 - $200
Train from Buffalo Depew Station Amtrak to Worcester Amtrak
Ave. Duration
9 h 53 min
Frequency
Once daily
Estimated price
$70 - $190
Website
amtrak.com
Coach Seat
$70 - $110
Flexi Coach Seat
$120 - $180
Business Coach Seat
$130 - $190
Room
$300 - $420
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Boston, Ma to Worcester, Ma
Ave. Duration
1 h
Frequency
Every 15 minutes
Estimated price
$11 - $24
Website
greyhound.com
Economy
$11 - $16
Flexible
$19 - $24
Bus from Albany, Ny to Worcester, Ma
Ave. Duration
2 h 55 min
Frequency
Every 30 minutes
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $29
Flexible
$35 - $45
Peter Pan Bus Lines
Phone
1-800-343-9999
Website
peterpanbus.com
Bus from Boston, MA - South Station to Worcester, MA - Union Station
Ave. Duration
1 h
Frequency
Every 3 hours
Estimated price
$13 - $18
Website
peterpanbus.com
Trailways New York

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More Questions & Answers

Buffalo–Depew Station to Worcester train services, operated by Amtrak, arrive at Worcester Amtrak station.

More details

Yes, the driving distance between Buffalo–Depew Station to Worcester is 411 miles. It takes approximately 7 h 1 min to drive from Buffalo–Depew Station to Worcester.

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Southwest Airlines, Delta, United Airlines and JetBlue Airways offer flights from Buffalo Airport to Boston Airport.

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Book your Buffalo–Depew Station to Worcester train tickets online with Rome2rio.

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There are 46+ hotels available in Worcester. Prices start at $89 USD per night.

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