Rome2Rio

How to get fromBuffalo Depew Station to Ithacaby train, bus, car or bus (Flixbus)

Find Transport to Ithaca

See all options

There are 5 ways to get from Buffalo Depew Station to Ithaca by train, bus, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus via Rochester

    best
    1. Take the train from Buffalo Depew Station to RochestertrainMaple Leaf / ...
    2. Take the bus from Rochester to IthacabusAdt N823 / ...
    3h 43m
    $37–134
  2. Drive 136.5 mi

    cheapest
    1. Drive from Buffalo Depew Station to Ithacacar136.5 mi
    3h 8m
    $25–36
  3. Train, bus

    1. Take the train from Buffalo Depew Station to Syracuse Regional Transportation CentertrainMaple Leaf / ...
    2. Take the bus from Syracuse Bus Station to IthacabusFlixBus 2691
    4h 16m
    $39–117
  4. Bus (Flixbus)

    1. Take the bus from Buffalo to IthacabusFlixBus 2685
    6h 6m
    $39–84
  5. Bus via Buffalo, NY

    1. Take the bus from Buffalo, NY to Ithaca, NYbusOurBus
    7h 3m
    $26–71

Buffalo Depew Station to Ithaca by train and bus

Calendar17Weekly Services
Duration3h 43mAverage Duration
Ticket$37Cheapest Price
See schedules

Questions & Answers

What companies run services between Buffalo Depew Station, NY, USA and Ithaca, NY, USA?

Flixbus USA operates a bus from Buffalo to Ithaca 6 times a week. Tickets cost $35–80 and the journey takes 3h 45m.

Transport is disrupted due to the Russia-Ukraine war. Read more

Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides