There are 10 ways to get from Bucharest to Isernia by plane, train, bus, train (Trenitalia), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Bucharest Otopeni to Roma Ciampino Airport, train
best- Fly from Bucharest Otopeni (OTP) to Roma Ciampino Airport (CIA)plane OTP - CIA
- Take the train from Ciampino to Iserniatrain
8h 1m€78–315Fly Bucharest Otopeni to Abruzzo Airport, bus
cheapest- Fly from Bucharest Otopeni (OTP) to Abruzzo Airport (PSR)plane OTP - PSR
- Take the bus from Pescara Airport to San Salvo Marinabus
- Take the bus from San Salvo Marina to Iserniabus
8h 46m€43–265Bus, train
- Take the bus from Bucureşti to Venezia, Viale Stazionebus
- Take the train from Venezia Mestre to Roma Terminitrain
- Take the train from Roma Termini to Iserniatrain Re
30h 12m€201–278Train
- Take the train from Bucuresti Nord to Budapest-Keletitrain Ir
- Take the train from Budapest-Keleti to Wien Hbftrain Ec / ...
- Take the train from Wien Hbf to Venezia Mestretrain Rjx
- Take the train from Venezia Mestre to Roma Terminitrain
- Take the train from Roma Termini to Iserniatrain Re
35h 33m€268–401Drive 1,913.2 km
- Drive from Bucharest to Iserniacar 1,913.2 km
21h 31m€309–446Fly Bucharest Otopeni to Fiumicino International Airport, train
- Fly from Bucharest Otopeni (OTP) to Fiumicino International Airport (FCO)plane OTP - FCO
- Take the train from Roma Termini to Iserniatrain
8h 26m€56–215Fly Bucharest Otopeni to Naples Airport, train
- Fly from Bucharest Otopeni (OTP) to Naples Airport (NAP)plane OTP - NAP
- Take the train from Caserta to Iserniatrain
8h 7m€58–253Fly Bucharest Băneasa Aurel Vlaicu International Airport to Naples Airport, train
- Fly from Bucharest Băneasa Aurel Vlaicu International Airport (BBU) to Naples Airport (NAP)plane BBU - NAP
- Take the train from Caserta to Iserniatrain
8h 42m€53–250Bus via Vienna
- Take the bus from Bucharest to Vienna, Central Station Südtiroler Platzbus
- Take the bus from Vienna Main train station to Rome Tiburtina Bus Stationbus
- Take the bus from Roma, Autostazione Tiburtina to Iserniabus
30h 30mBus
- Take the bus from Bucharest to Giulianovabus
- Take the bus from Pescara to Iserniabus 433
2d 6h€149–206
Bucharest to Isernia by train
Comparing Your Travel Options
The cheapest way to get from Bucharest to Isernia is to fly and train which costs €50 - €250 and takes 8h 42m.
The fastest way to get from Bucharest to Isernia is to fly and train which takes 8h 1m and costs €75 - €320.
No, there is no direct bus from Bucharest to Isernia. However, there are services departing from Bucharest and arriving at Isernia via Vienna Main train station and Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 30h 30m.
No, there is no direct train from Bucharest to Isernia. However, there are services departing from Bucuresti Nord and arriving at Isernia via Budapest-Keleti, Wien Hbf, Venezia Mestre and Roma Termini. The journey, including transfers, takes approximately 35h 33m.
The distance between Bucharest and Isernia is 1333 km. The road distance is 1913.2 km.
The best way to get from Bucharest to Isernia without a car is to bus and train which takes 30h 12m and costs €200 - €280.
It takes approximately 8h 1m to get from Bucharest to Isernia, including transfers.
Bucharest to Isernia bus services, operated by Maxibus Travel, depart from Bucharest station.
Bucharest to Isernia train services, operated by Romanian Railways (CFR), depart from Bucuresti Nord station.
The best way to get from Bucharest to Isernia is to train which takes 35h 33m and costs €260 - €410. Alternatively, you can bus via Vienna, which costs and takes 30h 30m.
What companies run services between Bucharest, Romania and Isernia, Italy?
You can take a train from Bucuresti Nord to Isernia via Budapest-Keleti, Wien Hbf, Venezia Mestre, and Roma Termini in around 35h 33m. Alternatively, you can take a bus from Bucharest to Isernia via Vienna Main train station and Roma, Autostazione Tiburtina in around 30h 30m.
- Website
- ryanair.com
Flights from Bucharest Otopeni to Roma Ciampino Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- €55–280
Flights from Bucharest Otopeni to Naples Airport
- Ave. Duration
- 2h
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €45–230
Flights from Bucharest Otopeni to Naples Airport via Thessaloniki
- Ave. Duration
- 4h 10m
- When
- Wednesday
- Estimated price
- €45–230
Flights from Bucharest Otopeni to Abruzzo Airport
- Ave. Duration
- 1h 50m
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- €30–240
- Website
- flyulendo.com
Flights from Bucharest Otopeni to Fiumicino International Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- €30–130
Flights from Bucharest Băneasa Aurel Vlaicu International Airport to Naples Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- €40–190
- Website
- airserbia.com
Flights from Bucharest Otopeni to Fiumicino International Airport via Belgrade
- Ave. Duration
- 4h 47m
- When
- Monday, Wednesday, Friday, Sunday, Thursday, and Saturday
- Estimated price
- €100–200
- Website
- tarom.ro
Flights from Bucharest Otopeni to Fiumicino International Airport
- Ave. Duration
- 3h 20m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- €60–230
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Ciampino to Isernia
- Ave. Duration
- 2h 6m
- Frequency
- Twice a week
- Estimated price
- €21–29
- Website
- Trenitalia
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- Every 3 hours
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- Every 3 hours
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- Every 3 hours
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Caserta to Isernia
- Ave. Duration
- 1h 17m
- Frequency
- Every 3 hours
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Caserta to Isernia
- Ave. Duration
- 1h 17m
- Frequency
- Every 3 hours
- Estimated price
- €10–15
- Website
- Trenitalia
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Venezia Mestre to Roma Termini
- Ave. Duration
- 3h 45m
- Frequency
- Every 2 hours
- Estimated price
- €60–100
- Website
- Italo Treno
Train from Venezia Mestre to Roma Termini
- Ave. Duration
- 3h 45m
- Frequency
- Every 2 hours
- Estimated price
- €60–100
- Website
- Italo Treno
- Phone
- 0219521
- Website
- Romanian Railways (CFR)
Train from Bucuresti Nord to Budapest-Keleti
- Ave. Duration
- 16h 26m
- Frequency
- Twice daily
- Estimated price
- €61–66
- Website
- Romanian Railways (CFR)
- Phone
- +36 (1) 3 49 49 49
- informacio@mavcsoport.hu
- Website
- Hungarian Railways (MÁV)
Train from Budapest-Keleti to Wien Hbf
- Ave. Duration
- 2h 50m
- Frequency
- Hourly
- Estimated price
- €12–14
- Website
- Hungarian Railways (MÁV)
- Phone
- +43 (0)5 1717
- Website
- Railjet
Train from Budapest-Keleti to Wien Hbf
- *
- €35–60
Train from Wien Hbf to Venezia Mestre
- *
- €90–140
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Bucureşti to Venezia, Viale Stazione
- Ave. Duration
- 22h 19m
- Frequency
- 3 times a week
- Estimated price
- €110–150
- Schedules at
- tabitatour.autogari.ro
- Phone
- 0865.221788
- info@satiautobus.com
- Website
- satiautobus.com
Bus from Pescara Airport to San Salvo Marina
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- €3–5
- Schedules at
- satiautobus.com
- Phone
- +39 0874 64744
- info@atm-molise.it
- Website
- atm-molise.it
Bus from San Salvo Marina to Isernia
- Ave. Duration
- 1h 12m
- Frequency
- Once a week
- Estimated price
- €4–6
- Schedules at
- atm-molise.it
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
Bus from Pescara to Isernia
- Ave. Duration
- 2h 20m
- Frequency
- 6 times a week
- Estimated price
- €7–11
- Schedules at
- atm-molise.it
- Phone
- +40 745 766 766
- dispecerat@maxibustravel.ro
- Website
- maxibustravel.autogari.ro
Bus from Bucharest to Vienna, Central Station Südtiroler Platz
- Ave. Duration
- 10h 55m
- Frequency
- Twice a week
- Schedules at
- maxibustravel.autogari.ro
- Phone
- +420 222 222 221
- info@regiojet.com
- Website
- RegioJet
Bus from Vienna Main train station to Rome Tiburtina Bus Station
- Ave. Duration
- 15h 25m
- Frequency
- Once a week
- Estimated price
- €65–110
- Website
- RegioJet
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- €14–22
- Website
- Flixbus
Bus from Pescara to Isernia
- Ave. Duration
- 2h 29m
- Frequency
- Once daily
- Estimated price
- €12–19
- Website
- Flixbus
- Phone
- 0040374557200
- Website
- romfour.com
Bus from Bucharest to Giulianova
- Ave. Duration
- 2d 2h
- Frequency
- Once a week
- Estimated price
- €130–180
- Schedules at
- romfour-door2door.autogari.ro
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Booking & Getting There
Bucharest to Isernia bus services, operated by Maxibus Travel, arrive at Vienna, Central Station Südtiroler Platz.
Isernia is 1h behind Bucharest. It is currently 11:04 PM in Bucharest and 10:04 PM in Isernia.
Bucharest to Isernia train services, operated by Romanian Railways (CFR), arrive at Budapest-Keleti station.
Yes, the driving distance between Bucharest to Isernia is 1913 km. It takes approximately 21h 31m to drive from Bucharest to Isernia.
Book your Bucharest to Isernia bus tickets online with Omio.
There are 453+ hotels available in Isernia.






































