There are 8 ways to get from Bryan to Port Isabel by bus (Greyhound), car, bus, plane, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Houston
best- Take the bus from Brazos Transit District to Houston Bus StationGreyhound US1100
- Take the bus from Houston - Harrisburg Blvd to Brownsville Bus StationHouston
11h 55m$107–157Drive 397.5 mi
cheapest- Drive from Bryan to Port Isabel397.5 mi
7h 51m$73–105Bus to George Bush Intercontinental Airport, fly to Brownsville-South Padre Island International Airport
- Take the bus from Brazos Transit District to Houston Bus Station
- Fly from George Bush Intercontinental Airport (IAH) to Brownsville-South Padre Island International Airport (BRO)IAH - BRO
7h 31m$94–469Bus
- Take the bus from Brazos Transit District to Houston Bus StationGreyhound US1100
- Take the bus from Houston Bus Station to La Plaza at BrownsvilleFlixBus US1126
12h 30m$77–157Bus via Matamoros
- Take the bus from Brazos Transit District to Houston Bus StationGreyhound US1100
- Take the bus from Houston to Matamoros
19h 13m$105–167Bus to William P. Hobby Airport, fly to Rio Grande Valley International Airport, bus
- Take the bus from Brazos Transit District to Houston Bus Station
- Fly from William P. Hobby Airport (HOU) to Rio Grande Valley International Airport (HRL)HOU - HRL
- Take the bus from Harlingen Bus Station to Brownsville
9h 28m$126–526Bus to George Bush Intercontinental Airport, fly to Mcallen Miller International Airport, bus
- Take the bus from Brazos Transit District to Houston Bus Station
- Fly from George Bush Intercontinental Airport (IAH) to Mcallen Miller International Airport (MFE)IAH - MFE
- Take the bus from McAllen Central Station to Brownsville
10h 8m$144–551Bus to George Bush Intercontinental Airport, fly to Rio Grande Valley International Airport, bus
- Take the bus from Brazos Transit District to Houston Bus Station
- Fly from George Bush Intercontinental Airport (IAH) to Rio Grande Valley International Airport (HRL)IAH - HRL
- Take the bus from Harlingen Bus Station to Brownsville
10h 29m$116–391
George Bush Intercontinental Airport (IAH) to Brownsville-South Padre Island International Airport (BRO) flights
Questions & Answers
The cheapest way to get from Bryan to Port Isabel is to drive which costs $70 - $110 and takes 7h 51m.
The fastest way to get from Bryan to Port Isabel is to bus and fly which takes 7h 31m and costs $90 - $470.
No, there is no direct bus from Bryan to Port Isabel. However, there are services departing from Brazos Transit District and arriving at Las Palmas Port Isabel via Houston - Harrisburg Blvd and La Plaza at Brownsville. The journey, including transfers, takes approximately 11h 55m.
The distance between Bryan and Port Isabel is 488 miles. The road distance is 399.8 miles.
The best way to get from Bryan to Port Isabel without a car is to bus via Houston which takes 11h 55m and costs $100 - $160.
It takes approximately 11h 55m to get from Bryan to Port Isabel, including transfers.
Bryan to Port Isabel bus services, operated by Greyhound USA, depart from Brazos Transit District station.
Bryan to Port Isabel bus services, operated by Greyhound USA, arrive at Houston Bus Station.
Yes, the driving distance between Bryan to Port Isabel is 400 miles. It takes approximately 7h 51m to drive from Bryan to Port Isabel.
There are 942+ hotels available in Port Isabel.
What companies run services between Bryan, Brazos County, TX, USA and Port Isabel, TX, USA?
You can take a bus from Brazos Transit District to Las Palmas Port Isabel via Houston Bus Station, Houston - Harrisburg Blvd, and La Plaza at Brownsville in around 11h 55m.
- Website
- united.com
Flights from George Bush Intercontinental Airport to Brownsville-South Padre Island International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $55–400
Flights from George Bush Intercontinental Airport to Mcallen Miller International Airport
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $60–420
Flights from George Bush Intercontinental Airport to Rio Grande Valley International Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $40–270
- Website
- southwest.com
Flights from William P. Hobby Airport to Rio Grande Valley International Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- $55–410
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Brazos Transit District to Houston Bus Station
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $29–60
- Website
- https://www.greyhound.com/
Bus from Houston Bus Station to La Plaza at Brownsville
- Ave. Duration
- 9h 20m
- Frequency
- 5 times a week
- Estimated price
- $45–85
- Website
- https://www.greyhound.com/
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Houston - Harrisburg Blvd to Brownsville Bus Station
- Ave. Duration
- 6h 55m
- Frequency
- 3 times a day
- Estimated price
- $75–95
- Schedules at
- omnibusexpress.com
Bus from Harlingen Bus Station to Brownsville
- Ave. Duration
- 25 min
- Frequency
- Once daily
- Estimated price
- $35–50
- Schedules at
- omnibusexpress.com
Bus from McAllen Central Station to Brownsville
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $40–55
- Schedules at
- omnibusexpress.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Houston Bus Station to La Plaza at Brownsville
- Ave. Duration
- 7h 30m
- Frequency
- Once daily
- Estimated price
- $45–95
- Schedules at
- flixbus.com
- Adult
- $45–95
- Phone
- +52 81 2152 6736
- info@conexionestornado.com
- Website
- tornadobus.com
Bus from Houston to Matamoros
- Ave. Duration
- 10h
- Frequency
- 4 times a day
- Estimated price
- $70
- Website
- https://tornadobus.com/en/home/
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