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  • Deutsche Bahn
  • Trenitalia
  • SNCF
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  • RENFE
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There are 11 ways to get from Brussels to Siena by plane, bus, train, car train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Brussels to Florence, bus  •  6 h 20 min

  1. Fly from Brussels (BRU) to Florence (FLR) BRU - FLR
  2. Take the bus from Stazione Leopolda to Siena-Via Tozzi

$92 - $403

Cheapest option

Fly Charleroi to Pisa, train  •  6 h 56 min

  1. Fly from Charleroi (CRL) to Pisa (PSA) CRL - PSA
  2. Take the train from Pisa C.Le to Empoli
  3. Take the train from Empoli to Siena

$49 - $201

9 alternative options

Fly Brussels to Bologna, train  •  7 h 25 min

  1. Fly from Brussels (BRU) to Bologna (BLQ) BRU - BLQ
  2. Take the train from Bologna C.Le to Firenze S.Maria Novella
  3. Take the train from Firenze Smn to Siena

$86 - $352

Train to Paris CDG, fly to Florence, bus  •  7 h 7 min

  1. Take the train from Brussel-Zuid/Midi to Airport Charles de Gaulle
  2. Fly from Paris CDG (CDG) to Florence (FLR) CDG - FLR
  3. Take the bus from Stazione Leopolda to Siena-Via Tozzi

$152 - $458

Fly Charleroi to Bologna, train  •  7 h 55 min

  1. Fly from Charleroi (CRL) to Bologna (BLQ) CRL - BLQ
  2. Take the train from Bologna C.Le to Firenze S.Maria Novella
  3. Take the train from Firenze Smn to Siena

$59 - $381

Train, train to Eindhoven, fly to Pisa  •  8 h 50 min

  1. Take the train from Brussel-Noord to Breda
  2. Take the train from Breda to Eindhoven
  3. Fly from Eindhoven (EIN) to Pisa (PSA) EIN - PSA
  4. Take the train from Pisa C.Le to Empoli
  5. Take the train from Empoli to Siena

$63 - $352

Train  •  13 h 49 min

  1. Take the train from Brussel-Zuid/Midi to Chambery
  2. Take the train from Chambery-Challes-E to Torino Porta Susa Tgv
  3. Take the train from Torino Porta Susa to Firenze S.Maria Novella Fr
  4. Take the train from Firenze Smn to Siena Reg

$313 - $404

Train, car train  •  20 h 29 min

  1. Take the train from Brusel Nord to Köln Hauptbahnhof Ice
  2. Take the car train from Köln Hbf to Verona Porta Nuova
  3. Take the train from Verona Porta Nuova to Bologna C.Le Fa / ...
  4. Take the train from Bologna C.Le to Firenze S.Maria Novella Fr / ...
  5. Take the train from Firenze Smn to Siena Reg

$143 - $265

Bus FlixBus  •  21 h

  1. Take the bus from Brussels, Brussels-North station to Milan, Milan N836
  2. Take the bus from Milano - Bus Station Lampugnano to SIENA - Piazza Gramsci Baltour / ...

$70 - $118

Bus Eurolines FR  •  23 h 8 min

  1. Take the bus from Brussels-North to Strasbourg
  2. Take the bus from Strasbourg to Firenze
  3. Take the bus from Firenze Autostazione to San Domenico 131

$140 - $254

Drive  •  12 h 35 min

  1. Drive from Brussels to Siena 782.8 miles

$180 - $280

Questions & Answers

The cheapest way to get from Brussels to Siena is to fly and train which costs 40€ - 180€ and takes 6 h 56 min.

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The quickest way to get from Brussels to Siena is to fly and bus which costs 80€ - 350€ and takes 6 h 20 min.

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No, there is no direct bus from Brussels station to Siena. However, there are services departing from Brussels, Brussels-North station and arriving at SIENA - Piazza Gramsci via Milano - Bus Station Lampugnano. The journey, including transfers, takes approximately 21 h.

More details

No, there is no direct train from Brussels to Siena. However, there are services departing from Brussel-Zuid/Midi and arriving at Siena via Chambery-Challes-E, Torino Porta Susa and Firenze Smn. The journey, including transfers, takes approximately 13 h 49 min.

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The distance between Brussels and Siena is 989 km. The road distance is 1252.5 km.

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The best way to get from Brussels to Siena without a car is to train which takes 13 h 49 min and costs 270€ - 360€.

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It takes approximately 6 h 20 min to get from Brussels to Siena, including transfers.

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Brussels to Siena bus services, operated by FlixBus, arrive at Brussels, Brussels-North station.

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Brussels to Siena train services, operated by Thalys, depart from Brussel-Zuid/Midi station.

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The best way to get from Brussels to Siena is to train which takes 13 h 49 min and costs 270€ - 360€. Alternatively, you can bus, which costs 60€ - 110€ and takes 21 h.

Mode details

Map of how to get from Brussels to Siena.
Launch map view
  • Distance: 618.4 miles
  • Duration: 6 h 20 min

What companies run services between Brussels, Belgium and Siena, Italy?

You can take a train from Brussels to Siena via Chambery, Chambery-Challes-E, Torino Porta Susa, Torino Porta Susa, Firenze S.Maria Novella, and Firenze Smn in around 13 h 49 min. Alternatively, you can take a bus from Brussels to Siena via Milano - Bus Station Lampugnano in around 21 h.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Brussels to Florence via Frankfurt
Ave. Duration
4 h 18 min
When
Every day
Estimated price
$200 - $900
Flights from Brussels to Florence via Munich
Ave. Duration
3 h 40 min
When
Every day
Estimated price
$200 - $900
Flights from Brussels to Bologna via Frankfurt
Ave. Duration
3 h 43 min
When
Every day
Estimated price
$170 - $850
Flights from Brussels to Bologna via Munich
Ave. Duration
3 h 38 min
When
Every day
Estimated price
$170 - $850
Flights from Paris CDG to Florence via Frankfurt
Ave. Duration
3 h 50 min
When
Every day
Estimated price
$200 - $850
Flights from Paris CDG to Florence via Munich
Ave. Duration
3 h 45 min
When
Every day
Estimated price
$200 - $850
KLM
Website
klm.com
Flights from Brussels to Florence via Amsterdam Schiphol
Ave. Duration
4 h
When
Every day
Estimated price
$160 - $650
Flights from Brussels to Bologna via Amsterdam Schiphol
Ave. Duration
4 h 5 min
When
Every day
Estimated price
$150 - $550
Flights from Paris CDG to Florence
Ave. Duration
1 h 45 min
When
Every day
Estimated price
$100 - $600
Flights from Paris CDG to Florence via Amsterdam Schiphol
Ave. Duration
4 h 20 min
When
Every day
Estimated price
$170 - $700
Air France
Website
airfrance.com
Flights from Paris CDG to Florence
Ave. Duration
1 h 44 min
When
Every day
Estimated price
$100 - $600
Swiss
Website
swiss.com
Flights from Brussels to Florence via Zurich
Ave. Duration
3 h 42 min
When
Every day
Estimated price
$240 - $1,200
Flights from Paris CDG to Florence via Zurich
Ave. Duration
3 h 45 min
When
Every day
Estimated price
$210 - $900
Ryanair
Website
ryanair.com
Flights from Charleroi to Pisa
Ave. Duration
1 h 45 min
When
Every day
Estimated price
$29 - $280
Flights from Charleroi to Bologna
Ave. Duration
1 h 40 min
When
Every day
Estimated price
$27 - $480
Flights from Eindhoven to Pisa
Ave. Duration
1 h 45 min
When
Monday, Tuesday, Thursday and Sunday
Estimated price
$35 - $300
Flights from Eindhoven to Pisa via London Stansted
Ave. Duration
4 h 30 min
When
Every day
Estimated price
$35 - $300
Brussels Airlines
Website
brusselsairlines.com
Flights from Brussels to Florence
Ave. Duration
1 h 55 min
When
Wednesday
Estimated price
$130 - $750
Flights from Brussels to Bologna
Ave. Duration
1 h 45 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$70 - $600
Flights from Paris CDG to Florence via Brussels
Ave. Duration
4 h 5 min
When
Wednesday
Estimated price
$460 - $2,100
Alitalia
Website
alitalia.com
Flights from Brussels to Florence via Rome
Ave. Duration
4 h 25 min
When
Every day
Estimated price
$190 - $800
Flights from Brussels to Bologna via Rome
Ave. Duration
4 h
When
Every day
Estimated price
$180 - $550
Flights from Paris CDG to Florence via Rome
Ave. Duration
4 h 5 min
When
Every day
Estimated price
$85 - $650
Austrian Airlines
Website
austrian.com
Flights from Brussels to Florence via Vienna
Ave. Duration
4 h 10 min
When
Every day
Estimated price
$310 - $1,200
Flights from Brussels to Bologna via Vienna
Ave. Duration
4 h 10 min
When
Tuesday, Wednesday, Thursday and Friday
Estimated price
$170 - $650
Train operators
Trenitalia Frecce

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Bologna C.Le to Firenze S.Maria Novella
Ave. Duration
34 min
Frequency
Every 30 minutes
Estimated price
$15 - $23
Website
orario.trenitalia.com
Train from Torino Porta Susa to Firenze S.Maria Novella
Ave. Duration
2 h 45 min
Frequency
Every 2 hours
Estimated price
$50 - $75
Website
orario.trenitalia.com
Train from Verona Porta Nuova to Bologna C.Le
Ave. Duration
50 min
Frequency
Hourly
Estimated price
$18 - $26
Website
orario.trenitalia.com
ItaloTreno
Phone
+39 060708
Website
italotreno.it
Train from Bologna Centrale Station to Firenze Santa Maria Novella Station
Ave. Duration
43 min
Frequency
Hourly
Estimated price
$17 - $25
Website
italotreno.it
Train from Verona Porta Nuova Station to Bologna Centrale Station
Ave. Duration
53 min
Frequency
3 times a day
Estimated price
$19 - $27
Website
italotreno.it
Trenitalia

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Bologna C.Le to Firenze Smn
Ave. Duration
1 h 30 min
Frequency
Twice daily
Estimated price
$7 - $16
Website
orario.trenitalia.com
1st Class
$13 - $16
Train from Firenze Smn to Siena
Ave. Duration
1 h 28 min
Frequency
Hourly
Estimated price
$7 - $16
Website
orario.trenitalia.com
1st Class
$13 - $16
Train from Pisa C.Le to Empoli
Ave. Duration
31 min
Frequency
Every 30 minutes
Estimated price
$3 - $9
Website
orario.trenitalia.com
1st Class
$7 - $9
Train from Empoli to Siena
Ave. Duration
1 h 6 min
Frequency
Every 30 minutes
Estimated price
$5 - $12
Website
orario.trenitalia.com
1st Class
$9 - $12
Thalys
Website
thalys.com
Train from Brussel-Zuid/Midi to Airport Charles de Gaulle
Ave. Duration
1 h 22 min
Frequency
Twice daily
Estimated price
$80 - $110
Website
thalys.com
2nd Class
$80 - $110
1st Class
$110 - $150
Train from Brussel-Zuid/Midi to Chambery
Ave. Duration
4 h 28 min
Frequency
Once a week
Estimated price
$210 - $270
Website
thalys.com
2nd Class
$210 - $270
1st Class
$280 - $390
Dutch Railways (NS)

Dutch Railways (NS) is the main passenger railway operator in the Netherlands. Founded in 1938, NS connects all major cities in the Netherlands, and offers night trains, international trains, Intercity direct, and trains to and from the airport. NS International is the international subsidiary of NS; their services include high-speed trains such as Thalys, ICE International, Eurostar and TGV, to major European hubs including Paris, London, Brussels, Berlin, Cologne, Frankfurt and Lille.

Contact Details
Phone
+31 30 751 5155
Website
ns.nl
Train from Brussel-Noord to Breda
Ave. Duration
1 h 23 min
Frequency
Hourly
Estimated price
$15 - $27
Website
ns.nl
Book at
eurail.com
Train from Breda to Eindhoven
Ave. Duration
37 min
Frequency
Hourly
Estimated price
$10 - $18
Website
ns.nl
Book at
eurail.com
Belgian Railways (NMBS/SNCB)
Phone
+32 2 528 28 28
Website
b-rail.be
Train from Brux.-Nord/Brus.-Noord to Breda
Ave. Duration
1 h 22 min
Frequency
Hourly
Estimated price
$12 - $18
Website
belgianrail.be
Book at
eurail.com
2nd Class
$12 - $18
1st Class
$18 - $27
inOui TGV
Phone
0033 892 353535
Website
en.oui.sncf
Train from Chambery-Challes-E to Torino Porta Susa
Ave. Duration
2 h 34 min
Frequency
3 times a day
Estimated price
$40 - $50
Website
en.oui.sncf
2nd Class
$40 - $50
1st Class
$65 - $80
Deutsche Bahn

Deutsche Bahn is the German railway company, and the largest railway operator and infrastructure owner in Europe. Based in Berlin, Deutsche Bahn was founded in 1994, and offers many different types of rail transportation including ICE or Intercity-Express for high-speed services between major cities and regions, IC (InterCity) for long-distance trains, RE (Regional Express) trains that connect regions and cities, and the S-Bahn rapid transit service. There are two main tickets on offer: the Flexpreis that has full flexibility, and the Sparpreis which is the cheaper, advanced fare.

Contact Details
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Brusel Nord to Köln Hauptbahnhof
Ave. Duration
1 h 41 min
Frequency
Every 4 hours
Estimated price
$45 - $70
Website
bahn.de
Urlaubs-Express
Phone
+49 (0) 221 800 20 820
Email
info@urlaubs-express.de
Website
urlaubs-express.de
Car train from Köln Hbf to Verona Porta Nuova
Ave. Duration
13 h 44 min
Frequency
Once a week
Estimated price
$65 - $140
Schedules at
urlaubs-express.de
Passenger
$68
Motorcycle
$114
Vehicle
$126
Bus operators
Tiemme Spa
Phone
+39.0565.260111
Email
segreteria@tiemmespa.it
Website
tiemmespa.it
Bus from Stazione Leopolda to Siena-Via Tozzi
Ave. Duration
1 h 13 min
Frequency
Hourly
Estimated price
$6 - $9
Schedules at
tiemmespa.it
Bus from Firenze Autostazione to San Domenico
Ave. Duration
1 h 15 min
Frequency
Hourly
Estimated price
$6 - $9
Schedules at
tiemmespa.it
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Brussels, Brussels-North station to Milan, Milan
Ave. Duration
13 h 20 min
Frequency
6 times a week
Estimated price
$50 - $85
Website
flixbus.co.uk
Bus from Milan, Milan to Siena, Siena
Ave. Duration
5 h 50 min
Frequency
Once daily
Estimated price
$20 - $35
Website
flixbus.co.uk
Baltour
Phone
+39 0861 1991900
Email
info@baltour.it
Website
baltour.it
Bus from Milano - Bus Station Lampugnano to SIENA - Piazza Gramsci
Ave. Duration
6 h 40 min
Frequency
5 times a day
Estimated price
$19 - $27
Website
http://www.baltour.it/
Eurolines FR
Phone
+ 33 1 41 86 24 21
Website
eurolines.fr
Bus from Brussels-North to Strasbourg
Ave. Duration
7 h
Frequency
6 times a week
Estimated price
$50 - $95
Schedules at
eurolines.fr
Bus from Strasbourg to Firenze
Ave. Duration
13 h 30 min
Frequency
4 times a week
Estimated price
$80 - $150
Schedules at
eurolines.fr

Want to know more about travelling around Italy

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More Questions & Answers

The quickest flight from Brussels Airport to Florence Airport is the direct flight which takes 1 h 55 min.

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Brussels to Siena bus services, operated by Baltour, arrive at SIENA - Piazza Gramsci station.

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Brussels to Siena train services, operated by Trenitalia, arrive at Siena station.

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Yes, the driving distance between Brussels to Siena is 1253 km. It takes approximately 12 h 35 min to drive from Brussels to Siena.

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Brussels Airlines, KLM, Austrian Airlines and four other airlines offer flights from Brussels Airport to Florence Airport.

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Book your Brussels to Siena bus tickets online with FlixBus and FlixBus.

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There are 2056+ hotels available in Siena. Prices start at $66 USD per night.

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The best way to get from Brussels to Brussels Airport is to train which takes 20 min and costs 4€ - 18€.

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