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How to get fromBrussels to Sienaby plane, train, train (Eurostar, Trenitalia), bus, car or car train

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There are 10 ways to get from Brussels to Siena by plane, train, train (Eurostar, Trenitalia), bus, car, or car train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Brussels Airport to Florence Peretola Airport, train

    best
    1. Fly from Brussels Airport (BRU) to Florence Peretola Airport (FLR)plane plane BRU - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    6h 41m
    €82–202
  2. Bus via Milan

    cheapest
    1. Take the bus from Brussels-North train station to Milano, Autostazione Lampugnanobus bus N836 / ...
    2. Take the bus from Milano, Autostazione Lampugnano to Sienabus bus N528 / ...
    17h 58m
    €57–124
  3. Train

    1. Take the train from Brussel-Zuid / Bruxelles-Midi to Chambery Challes Les Eauxtrain train
    2. Take the train from Chambery Challes Les Eaux to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    13h 24m
    €207–471
  4. Drive 1,231.5 km

    1. Drive from Brussels to Sienacar car 1,231.5 km
    12h 39m
    €189–273
  5. Bus to Brussels South Charleroi Airport, fly to Pisa International Airport, train

    1. Take the bus from Brussels Midi / Brussels South West to Charleroi Airportbus bus
    2. Fly from Brussels South Charleroi Airport (CRL) to Pisa International Airport (PSA)plane plane CRL - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    7h 10m
    €77–200
  6. Fly Brussels Airport to Bologna Guglielmo Marconi Airport, train

    1. Fly from Brussels Airport (BRU) to Bologna Guglielmo Marconi Airport (BLQ)plane plane BRU - BLQ
    2. Take the train from Bologna Centrale to Florence Santa Maria Novellatrain train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 22m
    €95–264
  7. Train to Amsterdam Airport Schiphol, fly to Florence Peretola Airport, train

    1. Take the train from Brussel-Zuid to Schiphol Airporttrain train
    2. Fly from Amsterdam Airport Schiphol (AMS) to Florence Peretola Airport (FLR)plane plane AMS - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 36m
    €122–298
  8. Bus to Brussels South Charleroi Airport, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the bus from Brussels Midi / Brussels South West to Charleroi Airportbus bus
    2. Fly from Brussels South Charleroi Airport (CRL) to Bologna Guglielmo Marconi Airport (BLQ)plane plane CRL - BLQ
    3. Take the train from Bologna Centrale to Florence Santa Maria Novellatrain train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    8h 19m
    €98–275
  9. Bus

    1. Take the bus from Brussels-North Station to Bolognabus bus
    2. Take the bus from Bologna Centrale to Siena Central Train Stationbus bus Itabus
    20h 9m
  10. Drive, car train

    1. Drive from Brussels to Düsseldorf Hbfcar car
    2. Take the car train from Düsseldorf Hbf to Villach Hbfcartrain train
    3. Drive from Villach Hbf to Sienacar car
    13h 41m
    €215–1,174

Brussels to Siena by train

Calendar3Weekly Trains
Duration13h 24mAverage Duration
Ticket€207Cheapest Price
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Questions & Answers

What companies run services between Brussels, Belgium and Siena, Italy?

You can take a train from Brussel-Zuid / Bruxelles-Midi to Siena via Chambery Challes Les Eaux, Milano Centrale, and Firenze S.M.N. in around 13h 24m. Alternatively, you can take a bus from Brussels-North train station to Siena via Milano, Autostazione Lampugnano in around 17h 58m.

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