There are 10 ways to get from Brussels to Siena by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Brussels to Florence, train  •  6 h 18 min

  1. Fly from Brussels (BRU) to Florence (FLR) BRU - FLR
  2. Take the train from Firenze Smn to Siena

$108 - $415

Cheapest option

Fly Charleroi to Pisa, train  •  7 h 5 min

  1. Fly from Charleroi (CRL) to Pisa (PSA) CRL - PSA
  2. Take the train from Pisa C.Le to Empoli
  3. Take the train from Empoli to Siena

$49 - $202

8 alternative options

Fly Brussels to Bologna, train  •  7 h 21 min

  1. Fly from Brussels (BRU) to Bologna (BLQ) BRU - BLQ
  2. Take the train from Bologna C.Le to Firenze S.Maria Novella
  3. Take the train from Firenze Smn to Siena

$110 - $355

Train to Amsterdam, fly to Florence, train  •  7 h 48 min

  1. Take the train from Brussel-Zuid/Midi to Schiphol Airport
  2. Fly from Amsterdam (AMS) to Florence (FLR) AMS - FLR
  3. Take the train from Firenze Smn to Siena

$131 - $374

Fly Charleroi to Bologna, train  •  8 h 4 min

  1. Fly from Charleroi (CRL) to Bologna (BLQ) CRL - BLQ
  2. Take the train from Bologna C.Le to Firenze S.Maria Novella
  3. Take the train from Firenze Smn to Siena

$68 - $384

Train  •  14 h 6 min

  1. Take the train from Brussel-Zuid/Midi to Paris-Nord
  2. Take the train from Paris Gare de Lyon to Torino Porta Susa Tgv
  3. Take the train from Torino Porta Susa to Firenze S.Maria Novella Fr
  4. Take the train from Firenze Smn to Siena Reg

$288 - $376

Train, bus  •  18 h 43 min

  1. Take the train from Bru.-Centraal / Brux.-Central to Luxembourg Ic
  2. Take the bus from Luxembourg, Luxembourg central station to Basel, Basel central station 299
  3. Take the train from Basel SBB to Milano Centrale Ec
  4. Take the train from Milano Centrale to Firenze S.Maria Novella Fr
  5. Take the train from Firenze Smn to Siena Reg

$174 - $303

Bus FlixBus  •  20 h 30 min

  1. Take the bus from Brussels, Brussels-North station to Milan, Milan
  2. Take the bus from Milano to Bologna 421 / ...
  3. Take the bus from Bologna, Bologna to Siena 519 / ...

$76 - $130

Bus Eurolines FR  •  23 h 8 min

  1. Take the bus from Brussels-North to Strasbourg
  2. Take the bus from Strasbourg to Firenze
  3. Take the bus from Firenze Autostazione to San Domenico 131

$141 - $256

Drive  •  12 h 35 min

  1. Drive from Brussels to Siena 782.8 miles

$180 - $280

Questions & Answers

The cheapest way to get from Brussels to Siena is to fly and train which costs 40€ - 180€ and takes 7 h 5 min.

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The quickest way to get from Brussels to Siena is to fly and train which costs 90€ - 360€ and takes 6 h 18 min.

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No, there is no direct bus from Brussels station to Siena. However, there are services departing from Brussels, Brussels-North station and arriving at Siena via Milano and Bologna, Bologna. The journey, including transfers, takes approximately 20 h 30 min.

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No, there is no direct train from Brussels to Siena. However, there are services departing from Brussel-Zuid/Midi and arriving at Siena via Paris Nord, Paris Gare de Lyon, Torino Porta Susa and Firenze Smn. The journey, including transfers, takes approximately 14 h 6 min.

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The distance between Brussels and Siena is 989 km. The road distance is 1252.5 km.

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The best way to get from Brussels to Siena without a car is to train which takes 14 h 6 min and costs 240€ - 320€.

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It takes approximately 6 h 18 min to get from Brussels to Siena, including transfers.

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Brussels to Siena bus services, operated by FlixBus, arrive at Brussels, Brussels-North station.

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Brussels to Siena train services, operated by Thalys, depart from Brussel-Zuid/Midi station.

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The best way to get from Brussels to Siena is to train which takes 14 h 6 min and costs 240€ - 320€. Alternatively, you can bus, which costs 60€ - 120€ and takes 20 h 30 min.

Mode details

Map of how to get from Brussels to Siena.
Launch map view
  • Distance: 618.4 miles
  • Duration: 6 h 18 min

What companies run services between Brussels, Belgium and Siena, Italy?

You can take a train from Brussels to Siena via Paris-Nord, Paris Nord, Paris Gare De Lyon, Paris Gare de Lyon, Torino Porta Susa, Torino Porta Susa, Firenze S.Maria Novella, and Firenze Smn in around 14 h 6 min. Alternatively, you can take a bus from Brussels to Siena via Milan, Milan, Milano, Bologna, and Bologna, Bologna in around 20 h 30 min.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Brussels to Florence via Frankfurt
Ave. Duration
3 h 51 min
When
Every day
Estimated price
$200 - $900
Flights from Brussels to Florence via Munich
Ave. Duration
3 h 25 min
When
Monday to Friday
Estimated price
$200 - $900
Flights from Brussels to Bologna via Frankfurt
Ave. Duration
3 h 48 min
When
Every day
Estimated price
$170 - $850
Flights from Brussels to Bologna via Munich
Ave. Duration
3 h 28 min
When
Every day
Estimated price
$170 - $850
Flights from Amsterdam to Florence via Frankfurt
Ave. Duration
3 h 53 min
When
Every day
Estimated price
$160 - $850
KLM
Website
klm.com
Flights from Brussels to Florence via Amsterdam
Ave. Duration
4 h 13 min
When
Every day
Estimated price
$160 - $650
Flights from Brussels to Bologna via Amsterdam
Ave. Duration
4 h 2 min
When
Every day
Estimated price
$150 - $550
Flights from Amsterdam to Florence
Ave. Duration
1 h 57 min
When
Every day
Estimated price
$180 - $600
Flights from Amsterdam to Florence via Paris CDG
Ave. Duration
3 h 50 min
When
Every day
Estimated price
$160 - $600
Swiss
Website
swiss.com
Flights from Brussels to Florence via Zurich
Ave. Duration
3 h 35 min
When
Every day
Estimated price
$240 - $1,200
Flights from Brussels to Florence via Geneva
Ave. Duration
4 h 25 min
When
Thursday
Estimated price
$130 - $750
Flights from Amsterdam to Florence via Zurich
Ave. Duration
3 h 35 min
When
Every day
Estimated price
$170 - $850
Ryanair
Website
ryanair.com
Flights from Charleroi to Pisa
Ave. Duration
1 h 50 min
When
Every day
Estimated price
$29 - $280
Flights from Charleroi to Bologna
Ave. Duration
1 h 40 min
When
Every day
Estimated price
$27 - $480
Air France
Website
airfrance.com
Flights from Brussels to Bologna via Lyon
Ave. Duration
3 h 25 min
When
Monday to Friday
Estimated price
$160 - $1,400
Flights from Amsterdam to Florence via Paris CDG
Ave. Duration
3 h 50 min
When
Every day
Estimated price
$160 - $600
Austrian Airlines
Website
austrian.com
Flights from Brussels to Bologna via Vienna
Ave. Duration
4 h 5 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$170 - $650
Flights from Amsterdam to Florence via Vienna
Ave. Duration
4 h 10 min
When
Every day
Estimated price
$250 - $900
Brussels Airlines
Website
brusselsairlines.com
Flights from Brussels to Florence
Ave. Duration
1 h 45 min
When
Every day
Estimated price
$130 - $750
Flights from Brussels to Bologna
Ave. Duration
1 h 40 min
When
Monday to Friday
Estimated price
$70 - $600
Alitalia
Website
alitalia.com
Flights from Brussels to Florence via Rome
Ave. Duration
4 h 25 min
When
Every day
Estimated price
$190 - $800
Flights from Brussels to Bologna via Rome
Ave. Duration
3 h 50 min
When
Every day
Estimated price
$180 - $550
Hop!
Website
hop.com
Flights from Brussels to Bologna via Lyon
Ave. Duration
3 h 25 min
When
Monday to Friday
Estimated price
$160 - $1,400
British Airways
Website
britishairways.com
Flights from Brussels to Bologna via London Heathrow
Ave. Duration
4 h 20 min
When
Every day
Estimated price
$150 - $700
Vueling Airlines
Website
vueling.com
Flights from Amsterdam to Florence
Ave. Duration
2 h
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$80 - $550
Train operators
Trenitalia

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Firenze Smn to Siena
Ave. Duration
1 h 28 min
Frequency
Hourly
Estimated price
$7 - $16
Website
orario.trenitalia.com
1st Class
$13 - $16
Train from Pisa C.Le to Empoli
Ave. Duration
31 min
Frequency
Every 30 minutes
Estimated price
$3 - $10
Website
orario.trenitalia.com
1st Class
$7 - $10
Train from Empoli to Siena
Ave. Duration
1 h 6 min
Frequency
Every 30 minutes
Estimated price
$5 - $12
Website
orario.trenitalia.com
1st Class
$9 - $12
Trenitalia Frecce

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Bologna C.Le to Firenze S.Maria Novella
Ave. Duration
34 min
Frequency
Every 30 minutes
Estimated price
$16 - $23
Website
orario.trenitalia.com
Train from Torino Porta Susa to Firenze S.Maria Novella
Ave. Duration
2 h 45 min
Frequency
Every 2 hours
Estimated price
$50 - $80
Website
orario.trenitalia.com
Train from Milano Centrale to Firenze S.Maria Novella
Ave. Duration
1 h 39 min
Frequency
Hourly
Estimated price
$35 - $60
Website
orario.trenitalia.com
Thalys
Website
thalys.com
Train from Brussel-Zuid/Midi to Schiphol Airport
Ave. Duration
1 h 32 min
Frequency
Hourly
Estimated price
$55 - $80
Website
thalys.com
2nd Class
$55 - $80
1st Class
$85 - $110
Train from Brussel-Zuid/Midi to Paris-Nord
Ave. Duration
1 h 22 min
Frequency
Every 2 hours
Estimated price
$85 - $120
Website
thalys.com
2nd Class
$85 - $120
1st Class
$120 - $170
TGV
Phone
0033 892 353535
Website
sncf.com
Train from Paris Gare de Lyon to Torino Porta Susa
Ave. Duration
5 h 37 min
Frequency
3 times a day
Estimated price
$140 - $160
Website
en.oui.sncf
2nd Class
$140 - $160
1st Class
$180 - $270
Belgian Railways (NMBS/SNCB)
Phone
+32 2 528 28 28
Website
b-rail.be
Train from Bru.-Centraal / Brux.-Central to Luxembourg
Ave. Duration
3 h 13 min
Frequency
Every 4 hours
Estimated price
$22 - $35
Website
belgianrail.be
Book at
eurail.com
2nd Class
$22 - $35
1st Class
$30 - $50
Swiss Railways (SBB/CFF/FFS)

The national railway company of Switzerland, Swiss Railways operates trains throughout the country and adjacent European nations including Germany, France, Italy and Austria. Tickets are sold in two classes - First and Second - with most long-distance trains offering a bistro car serving beverages and snacks. Individual tickets can be bought easily at stands, while a variety of travel passes are on offer to suit different travel needs. Swiss Railways codeshares with American Airlines and Swiss International Air Lines out of Zurich International Airport.

Contact Details
Website
sbb.ch
Train from Basel SBB to Milano Centrale
Ave. Duration
4 h 6 min
Frequency
4 times a day
Estimated price
$90 - $160
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Trenitalia Eurocity

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Basel Sbb to Milano Centrale
Ave. Duration
4 h 6 min
Frequency
3 times a day
Estimated price
$60 - $85
Website
orario.trenitalia.com
Bus operators
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Luxembourg, Luxembourg central station to Basel, Basel central station
Ave. Duration
5 h
Frequency
Twice daily
Estimated price
$20 - $35
Website
flixbus.co.uk
Bus from Brussels, Brussels-North station to Milan, Milan
Ave. Duration
13 h 20 min
Frequency
Once daily
Estimated price
$50 - $90
Website
flixbus.co.uk
Bus from Milan, Milan to Bologna, Bologna
Ave. Duration
2 h 50 min
Frequency
3 times a day
Estimated price
$15 - $26
Website
flixbus.co.uk
Bus from Bologna, Bologna to Siena
Ave. Duration
2 h 30 min
Frequency
Every 4 hours
Estimated price
$9 - $16
Website
flixbus.co.uk
Marozzi VT
Phone
080 579 0211
Email
info@marozzivt.it
Website
marozzivt.it
Bus from Milano to Bologna
Ave. Duration
2 h 40 min
Frequency
Every 4 hours
Estimated price
$24 - $29
Schedules at
marozzivt.it
Saj
Phone
0981 500331
Email
info@saj.it
Website
saj.it
Bus from Milano Lampugnano to Bologna
Ave. Duration
2 h 50 min
Frequency
Once daily
Estimated price
$20
Schedules at
saj.it
Baltour
Phone
+39 0861 1991900
Email
info@baltour.it
Website
baltour.it
Bus from Bologna - Terminal Bus 200 Mt. Da Stazione Fs to SIENA - Pza Stazione FS-Fta SENA
Ave. Duration
3 h
Frequency
5 times a day
Estimated price
$10 - $14
Website
http://www.baltour.it/
Eurolines FR
Phone
+ 33 1 41 86 24 21
Website
eurolines.fr
Bus from Brussels-North to Strasbourg
Ave. Duration
7 h
Frequency
6 times a week
Estimated price
$55 - $100
Schedules at
eurolines.fr
Bus from Strasbourg to Firenze
Ave. Duration
13 h 30 min
Frequency
4 times a week
Estimated price
$80 - $150
Schedules at
eurolines.fr
Tiemme Spa

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More Questions & Answers

The quickest flight from Brussels Airport to Florence Airport is the direct flight which takes 1 h 45 min.

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Brussels to Siena bus services, operated by FlixBus, arrive at Siena station.

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Brussels to Siena train services, operated by Trenitalia, arrive at Siena station.

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Yes, the driving distance between Brussels to Siena is 1253 km. It takes approximately 12 h 35 min to drive from Brussels to Siena.

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Air Dolomiti, Brussels Airlines, Alitalia and three other airlines offer flights from Brussels Airport to Florence Airport.

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There are 1735+ hotels available in Siena. Prices start at $72 USD per night.

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The best way to get from Brussels to Brussels Airport is to train which takes 12 min and costs 16€ - 18€.

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