There are 10 ways to get from Brussels to Siena by plane, train, train (Eurostar, Trenitalia), bus, car, or car train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Brussels Airport to Florence Peretola Airport, train
best- Fly from Brussels Airport (BRU) to Florence Peretola Airport (FLR)plane BRU - FLR
- Take the train from Firenze S.M.N. to Sienatrain
6h 41m€82–202Bus via Milan
cheapest- Take the bus from Brussels-North train station to Milano, Autostazione Lampugnanobus N836 / ...
- Take the bus from Milano, Autostazione Lampugnano to Sienabus N528 / ...
17h 58m€57–124Train
- Take the train from Brussel-Zuid / Bruxelles-Midi to Chambery Challes Les Eauxtrain
- Take the train from Chambery Challes Les Eaux to Milano Centraletrain Fr
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
13h 24m€207–471Drive 1,231.5 km
- Drive from Brussels to Sienacar 1,231.5 km
12h 39m€189–273Bus to Brussels South Charleroi Airport, fly to Pisa International Airport, train
- Take the bus from Brussels Midi / Brussels South West to Charleroi Airportbus
- Fly from Brussels South Charleroi Airport (CRL) to Pisa International Airport (PSA)plane CRL - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
7h 10m€77–200Fly Brussels Airport to Bologna Guglielmo Marconi Airport, train
- Fly from Brussels Airport (BRU) to Bologna Guglielmo Marconi Airport (BLQ)plane BRU - BLQ
- Take the train from Bologna Centrale to Florence Santa Maria Novellatrain
- Take the train from Firenze S.M.N. to Sienatrain
7h 22m€95–264Train to Amsterdam Airport Schiphol, fly to Florence Peretola Airport, train
- Take the train from Brussel-Zuid to Schiphol Airporttrain
- Fly from Amsterdam Airport Schiphol (AMS) to Florence Peretola Airport (FLR)plane AMS - FLR
- Take the train from Firenze S.M.N. to Sienatrain
8h 36m€122–298Bus to Brussels South Charleroi Airport, fly to Bologna Guglielmo Marconi Airport, train
- Take the bus from Brussels Midi / Brussels South West to Charleroi Airportbus
- Fly from Brussels South Charleroi Airport (CRL) to Bologna Guglielmo Marconi Airport (BLQ)plane CRL - BLQ
- Take the train from Bologna Centrale to Florence Santa Maria Novellatrain
- Take the train from Firenze S.M.N. to Sienatrain
8h 19m€98–275Bus
- Take the bus from Brussels-North Station to Bolognabus
- Take the bus from Bologna Centrale to Siena Central Train Stationbus Itabus
20h 9mDrive, car train
- Drive from Brussels to Düsseldorf Hbfcar
- Take the car train from Düsseldorf Hbf to Villach Hbfcartrain
- Drive from Villach Hbf to Sienacar
13h 41m€215–1,174
Brussels to Siena by train
Questions & Answers
The cheapest way to get from Brussels to Siena is to bus via Milan which costs €55 - €130 and takes 17h 58m.
The fastest way to get from Brussels to Siena is to fly and train which takes 6h 41m and costs €80 - €210.
No, there is no direct bus from Brussels station to Siena. However, there are services departing from Brussels-North train station and arriving at Siena via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 17h 58m.
No, there is no direct train from Brussels to Siena. However, there are services departing from Brussel-Zuid / Bruxelles-Midi and arriving at Siena via Chambery Challes Les Eaux, Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 13h 24m.
The distance between Brussels and Siena is 1047 km. The road distance is 1231.5 km.
The best way to get from Brussels to Siena without a car is to train which takes 13h 24m and costs €200 - €480.
It takes approximately 6h 41m to get from Brussels to Siena, including transfers.
Brussels to Siena bus services, operated by FlixBus, depart from Brussels-North train station.
Brussels to Siena train services, operated by Eurostar, depart from Brussel-Zuid / Bruxelles-Midi station.
The best way to get from Brussels to Siena is to train which takes 13h 24m and costs €200 - €480. Alternatively, you can bus via Milan, which costs €55 - €130 and takes 17h 58m.
What companies run services between Brussels, Belgium and Siena, Italy?
You can take a train from Brussel-Zuid / Bruxelles-Midi to Siena via Chambery Challes Les Eaux, Milano Centrale, and Firenze S.M.N. in around 13h 24m. Alternatively, you can take a bus from Brussels-North train station to Siena via Milano, Autostazione Lampugnano in around 17h 58m.
- Website
- lufthansa.com
Flights from Brussels Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 37m
- When
- Every day
- Estimated price
- €75–280
Flights from Brussels Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 3h 57m
- When
- Monday, Wednesday, and Sunday
- Estimated price
- €75–380
Flights from Brussels Airport to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- €75–230
Flights from Brussels Airport to Bologna Guglielmo Marconi Airport via Frankfurt
- Ave. Duration
- 3h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €100–310
Flights from Amsterdam Airport Schiphol to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 4h 1m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €100–550
Flights from Amsterdam Airport Schiphol to Florence Peretola Airport via Munich
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- €100–270
- Website
- ryanair.com
Flights from Brussels South Charleroi Airport to Pisa International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €30–170
Flights from Brussels South Charleroi Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €50–200
- Website
- swiss.com
Flights from Brussels Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 4h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €70–200
Flights from Brussels Airport to Bologna Guglielmo Marconi Airport via Zurich
- Ave. Duration
- 4h 10m
- When
- Tuesday and Wednesday
- Estimated price
- €75–210
Flights from Amsterdam Airport Schiphol to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €100–250
- Website
- klm.com
Flights from Amsterdam Airport Schiphol to Florence Peretola Airport
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- €75–450
- Website
- brusselsairlines.com
Flights from Brussels Airport to Florence Peretola Airport
- Ave. Duration
- 1h 45m
- When
- Monday, Wednesday, Thursday, and Sunday
- Estimated price
- €75–270
Flights from Brussels Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 35m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €75–210
- Website
- vueling.com
Flights from Brussels Airport to Florence Peretola Airport
- Ave. Duration
- 1h 45m
- When
- Thursday and Sunday
- Estimated price
- €45–160
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11
- Website
- https://www.trenitalia.com/en.html
Train from Chambery Challes Les Eaux to Milano Centrale
- Ave. Duration
- 3h 21m
- Frequency
- Twice daily
- Estimated price
- €55–130
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €7
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €8
- Website
- https://www.trenitalia.com/en.html
- Phone
- +44 343 218 6186
- Website
- eurostar.com
Train from Brussel-Zuid / Bruxelles-Midi to Chambery Challes Les Eaux
- Ave. Duration
- 4h 11m
- Frequency
- 3 times a week
- Estimated price
- €120–250
- Website
- https://www.eurostar.com/rw-en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €30–85
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- Once daily
- Estimated price
- €20–65
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Bologna Centrale to Florence Santa Maria Novella
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Estimated price
- €13–35
- Website
- https://www.italotreno.it/en
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Brussel-Zuid to Schiphol Airport
- Ave. Duration
- 1h 58m
- Frequency
- Hourly
- Estimated price
- €28–55
- Website
- https://www.ns.nl/en
- Phone
- +49 (0) 221 800 20 820
- info@urlaubs-express.de
- Website
- urlaubs-express.de
Car train from Düsseldorf Hbf to Villach Hbf
- Ave. Duration
- 5h 53m
- Frequency
- Once a week
- Estimated price
- €100–1,000
- Website
- https://urlaubs-express.de/?lang=en
- Car Single Bed
- €270–550
- Car Compartment
- €550–1,000
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Brussels-North train station to Milano, Autostazione Lampugnano
- Ave. Duration
- 12h 25m
- Frequency
- Once daily
- Estimated price
- €45–90
- Website
- https://www.flixbus.co.uk
Bus from Milano, Autostazione Lampugnano to Siena
- Ave. Duration
- 4h 55m
- Frequency
- Every 4 hours
- Estimated price
- €11–26
- Website
- https://www.flixbus.co.uk
Bus from Bologna Centrale to Siena Central Train Station
- Ave. Duration
- 2h 35m
- Frequency
- Every 4 hours
- Estimated price
- €6–16
- Website
- https://www.flixbus.co.uk
- Website
- global.flixbus.com
Bus from Brussels-North train station to Milano, Autostazione Lampugnano
- Ave. Duration
- 12h 25m
- Frequency
- Once daily
- Schedules at
- global.flixbus.com
Bus from Milano, Autostazione Lampugnano to Siena
- Ave. Duration
- 6h 35m
- Frequency
- Every 4 hours
- Schedules at
- global.flixbus.com
Bus from Bologna Centrale to Siena Central Train Station
- Ave. Duration
- 2h 40m
- Frequency
- Every 4 hours
- Schedules at
- global.flixbus.com
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Milano, Autostazione Lampugnano to Siena
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- €9–35
- Website
- https://www.itabus.it/en/home
Bus from Bologna Centrale to Siena Central Train Station
- Ave. Duration
- 2h 20m
- Frequency
- 4 times a day
- Estimated price
- €5–40
- Website
- https://www.itabus.it/en/home
- info@flibco.com
- Website
- flibco.com
Bus from Brussels Midi / Brussels South West to Charleroi Airport
- Ave. Duration
- 55 min
- Frequency
- Every 30 minutes
- Estimated price
- €16–21
- Website
- https://www.flibco.com/en
- Phone
- +393293958604
- info@pistoiaviaggi.com
- Website
- pistoia-viaggi.it
Bus from Brussels-North Station to Bologna
- Ave. Duration
- 17h 10m
- Frequency
- Once a week
- Schedules at
- pistoia-viaggi.it
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More Questions & Answers
Brussels to Siena bus services, operated by FlixBus, arrive at Milano, Autostazione Lampugnano station.
Brussels to Siena train services, operated by Eurostar, arrive at Chambery Challes Les Eaux station.
Yes, the driving distance between Brussels to Siena is 1232 km. It takes approximately 12h 39m to drive from Brussels to Siena.
Book your Brussels to Siena train tickets online with Omio.
Book your Brussels to Siena bus tickets online with Omio and FlixBus.
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