There are 8 ways to get from Brussels to Grenoble by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  5 h 39 min

  1. Take the train from Brussel-Zuid/Midi to Paris-Nord Thalys
  2. Take the train from Paris Gare de Lyon to Grenoble Tgv / ...

$201 - $250

Cheapest option

Bus FlixBus  •  13 h 24 min

  1. Take the bus from Brussels, Brussels-North station to Lyon, Lyon Perrache N769
  2. Take the bus from Lyon - Perrache Bus station to Grenoble - Bus station Ouibus / ...

$51 - $148

6 alternative options

Bus Isilines  •  13 h 15 min

  1. Take the bus from Brussels-North to Paris Gallieni
  2. Take the bus from Paris - Gallieni to Grenoble

$58 - $137

Drive  •  7 h 58 min

  1. Drive from Brussels to Grenoble 525.5 miles

$110 - $170

Fly Brussels to Lyon, train  •  5 h 35 min

  1. Fly from Brussels (BRU) to Lyon (LYS) BRU - LYS
  2. Take the train from Lyon-St Exupery(TGV) to Grenoble

$83 - $254

Fly Brussels to Geneva, train  •  7 h 6 min

  1. Fly from Brussels (BRU) to Geneva (GVA) BRU - GVA
  2. Take the train from Genève to Grenoble

$95 - $265

Train to Lille Lesquin, fly to Lyon, train  •  5 h 59 min

  1. Take the train from Brussels - Midi to Gare de Lille Europe
  2. Fly from Lille Lesquin (LIL) to Lyon (LYS) LIL - LYS
  3. Take the train from Lyon-St Exupery(TGV) to Grenoble

$119 - $376

Train to Paris CDG, fly to Lyon, train  •  6 h 12 min

  1. Take the train from Brussel-Zuid/Midi to Paris-Nord
  2. Fly from Paris CDG (CDG) to Lyon (LYS) CDG - LYS
  3. Take the train from Lyon-St Exupery(TGV) to Grenoble

$178 - $400

Questions & Answers

The cheapest way to get from Brussels to Grenoble is to bus which costs 45€ - 120€ and takes 13 h 15 min.

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The quickest way to get from Brussels to Grenoble is to fly and train which costs 70€ - 220€ and takes 5 h 35 min.

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No, there is no direct bus from Brussels to Grenoble. However, there are services departing from Brussels-North and arriving at Grenoble via Paris - Gallieni. The journey, including transfers, takes approximately 13 h 15 min.

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No, there is no direct train from Brussels to Grenoble. However, there are services departing from Brussel-Zuid/Midi and arriving at Grenoble via Paris Nord and Paris Gare de Lyon. The journey, including transfers, takes approximately 5 h 39 min.

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The distance between Brussels and Grenoble is 640 km. The road distance is 840.9 km.

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The best way to get from Brussels to Grenoble without a car is to train which takes 5 h 39 min and costs 170€ - 220€.

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It takes approximately 5 h 39 min to get from Brussels to Grenoble, including transfers.

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Brussels to Grenoble bus services, operated by FlixBus, arrive at Brussels, Brussels-North station.

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Brussels to Grenoble train services, operated by Thalys, depart from Brussel-Zuid/Midi station.

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The best way to get from Brussels to Grenoble is to train which takes 5 h 39 min and costs 170€ - 220€. Alternatively, you can bus, which costs 45€ - 120€ and takes 13 h 15 min.

Mode details

Map of how to get from Brussels to Grenoble.
Launch map view
  • Distance: 399.8 miles
  • Duration: 5 h 39 min

What companies run services between Brussels, Belgium and Grenoble, France?

You can take a train from Brussels to Grenoble via Paris-Nord, Paris Nord, Paris Gare De Lyon, and Paris Gare de Lyon in around 5 h 39 min. Alternatively, you can take a bus from Brussels to Grenoble via Paris Gallieni and Paris - Gallieni in around 13 h 15 min.

Airlines
Air France
Website
airfrance.com
Flights from Brussels to Lyon
Ave. Duration
1 h 25 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$75 - $430
Flights from Lille Lesquin to Lyon
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$100 - $450
Flights from Paris CDG to Lyon
Ave. Duration
1 h 8 min
When
Every day
Estimated price
$50 - $310
Lufthansa
Website
lufthansa.com
Flights from Brussels to Lyon via Frankfurt
Ave. Duration
3 h 16 min
When
Every day
Estimated price
$160 - $600
Flights from Brussels to Lyon via Munich
Ave. Duration
3 h 20 min
When
Every day
Estimated price
$160 - $600
Flights from Brussels to Geneva via Frankfurt
Ave. Duration
3 h 4 min
When
Every day
Estimated price
$150 - $650
Flights from Brussels to Geneva via Munich
Ave. Duration
3 h 15 min
When
Every day
Estimated price
$150 - $650
Brussels Airlines
Website
brusselsairlines.com
Flights from Brussels to Lyon
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$60 - $370
Flights from Brussels to Geneva
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$60 - $460
Swiss
Website
swiss.com
Flights from Brussels to Geneva
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$60 - $460
Flights from Brussels to Geneva via Zurich
Ave. Duration
3 h 15 min
When
Every day
Estimated price
$110 - $400
Hop!
Website
hop.com
Flights from Brussels to Lyon
Ave. Duration
1 h 25 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$75 - $430
Flights from Lille Lesquin to Lyon
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$100 - $450
easyJet
Website
easyjet.com
Flights from Brussels to Geneva
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$45 - $290
XL Airways France
Website
xl.com
Flights from Paris CDG to Lyon
Ave. Duration
1 h 10 min
When
Wednesday
Estimated price
$29 - $130
Train operators
Thalys
Website
thalys.com
Train from Brussel-Zuid/Midi to Paris-Nord
Ave. Duration
1 h 22 min
Frequency
Every 2 hours
Estimated price
$85 - $120
Website
thalys.com
2nd Class
$85 - $120
1st Class
$120 - $170
Train from Brussel-Zuid/Midi to Lille Europe
Ave. Duration
36 min
Frequency
6 times a week
Estimated price
$30 - $55
Website
thalys.com
2nd Class
$30 - $55
1st Class
$55 - $70
TGV
Phone
0033 892 353535
Website
sncf.com
Train from Paris Gare de Lyon to Grenoble
Ave. Duration
3 h
Frequency
Every 2 hours
Estimated price
$110 - $130
Website
en.oui.sncf
2nd Class
$110 - $130
1st Class
$140 - $210
Train from Lyon-St Exupery(TGV) to Grenoble
Ave. Duration
1 h 3 min
Frequency
Every 2 hours
Estimated price
$28 - $33
Website
en.oui.sncf
2nd Class
$28 - $33
1st Class
$47 - $51
Train from Brussels - Midi to Gare de Lille Europe
Ave. Duration
34 min
Frequency
Every 4 hours
Estimated price
$26 - $31
Website
en.oui.sncf
2nd Class
$26 - $31
1st Class
$45 - $48
Swiss Railways (SBB/CFF/FFS)

The national railway company of Switzerland, Swiss Railways operates trains throughout the country and adjacent European nations including Germany, France, Italy and Austria. Tickets are sold in two classes - First and Second - with most long-distance trains offering a bistro car serving beverages and snacks. Individual tickets can be bought easily at stands, while a variety of travel passes are on offer to suit different travel needs. Swiss Railways codeshares with American Airlines and Swiss International Air Lines out of Zurich International Airport.

Contact Details
Website
sbb.ch
Train from Genève to Grenoble
Ave. Duration
2 h 15 min
Frequency
Every 4 hours
Estimated price
$30 - $55
Website
fahrplan.sbb.ch
Schedules at
fahrplan.sbb.ch
Bus operators
Eurolines FR
Phone
+ 33 1 41 86 24 21
Website
eurolines.fr
Bus from Brussels-North to Paris Gallieni
Ave. Duration
4 h 15 min
Frequency
Every 2 hours
Estimated price
$28 - $85
Schedules at
eurolines.fr
Bus from Brussels-North to Lyon
Ave. Duration
11 h 30 min
Frequency
Once daily
Estimated price
$95 - $140
Schedules at
eurolines.fr
Isilines
Phone
0 892 89 12 00
Website
isilines.com
Bus from Paris - Gallieni to Grenoble
Ave. Duration
8 h
Frequency
3 times a week
Estimated price
$30 - $55
Schedules at
isilines.com
Bus from Lyon to Grenoble
Ave. Duration
1 h 11 min
Frequency
Once daily
Estimated price
$7 - $10
Schedules at
isilines.com
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Brussels, Brussels-North station to Lyon, Lyon Perrache
Ave. Duration
11 h
Frequency
Once daily
Estimated price
$45 - $80
Website
flixbus.co.uk
Bus from Lyon, Lyon Perrache to Grenoble
Ave. Duration
1 h 30 min
Frequency
Every 4 hours
Estimated price
$6 - $10
Website
flixbus.co.uk
Ouibus

As the bus subsidiary of French railway SNCF, Ouibus offers comfortable, eco-friendly coaches serving 35 French cities and 11 European cities at affordable fares. Ouibus journeys are safe and comfortable, with the four-star coaches offering power outlets, restrooms and WiFi. All Ouibus stations are located close to town centres for easy access to public transport. Getting on one of the 130 daily journeys is easy - electronic travel documents include your ticket and a personalised mini-guide with handy information.

Contact Details
Phone
0890715298
Website
ouibus.com
Bus from Lyon - Perrache Bus station to Grenoble - Bus station
Ave. Duration
1 h 30 min
Frequency
Every 4 hours
Estimated price
$4 - $6
Website
Ouibus

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More Questions & Answers

The quickest flight from Brussels Airport to Lyon Airport is the direct flight which takes 1 h 20 min.

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Brussels to Grenoble bus services, operated by Ouibus, arrive at Grenoble - Bus station.

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Brussels to Grenoble train services, operated by TGV, arrive at Grenoble station.

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Yes, the driving distance between Brussels to Grenoble is 841 km. It takes approximately 7 h 58 min to drive from Brussels to Grenoble.

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Brussels Airlines, Hop! and Lufthansa offer flights from Brussels Airport to Lyon Airport.

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There are 384+ hotels available in Grenoble. Prices start at $57 USD per night.

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The best way to get from Brussels to Brussels Airport is to train which takes 12 min and costs 16€ - 18€.

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