There are 12 ways to get from Brussels to Comiso by plane, bus, train, car, car ferry, train (Eurostar, TGV, Trenitalia), or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Brussels Airport to Catania–Fontanarossa Airport, bus
best- Fly from Brussels Airport (BRU) to Catania–Fontanarossa Airport (CTA)plane BRU - CTA
- Take the bus from Catania Fontanarossa Airport Bus Stop to Gela Bus Stationbus
8h 49m€87–210Bus to Brussels South Charleroi Airport, fly to Catania–Fontanarossa Airport, bus
cheapest- Take the bus from Brussels Midi / Brussels South West to Charleroi Airportbus
- Fly from Brussels South Charleroi Airport (CRL) to Catania–Fontanarossa Airport (CTA)plane CRL - CTA
- Take the bus from Catania Fontanarossa Airport Bus Stop to Gela Bus Stationbus
9h 33m€72–229Train, bus
- Take the train from Brussel-Zuid / Bruxelles-Midi to Paris Nordtrain
- Take the train from Paris Gare De Lyon to Torino Porta Susatrain Tgv
- Take the train from Torino Porta Susa to Villa S.Giovannitrain Fr
- Take the bus from Villa San Giovanni-Piazza Stazione to Gela Bus Stationbus
25h 57m€322–831Drive, car ferry
- Drive from Brussels to Port of Genoacar
- Take the car ferry from Port of Genoa to Port of Palermocarferry
- Drive from Port of Palermo to Comisocar
34h 31m€285–431Bus
- Take the bus from Brussels-North Station to Bolognabus
- Take the bus from Bologna Centrale to Gela Bus Stationbus Autoservizi Salemi S121 / ...
36h 55mFly Brussels Airport to Vincenzo Magliocco Airport
- Fly from Brussels Airport (BRU) to Vincenzo Magliocco Airport (CIY)plane BRU - CIY
6h 29m€125–400Bus to Brussels South Charleroi Airport, fly to Vincenzo Magliocco Airport
- Take the bus from Brussels Midi / Brussels South West to Charleroi Airportbus
- Fly from Brussels South Charleroi Airport (CRL) to Vincenzo Magliocco Airport (CIY)plane CRL - CIY
7h 38m€100–319Bus to Brussels South Charleroi Airport, fly to Palermo Airport, train
- Take the bus from Brussels Midi / Brussels South West to Charleroi Airportbus
- Fly from Brussels South Charleroi Airport (CRL) to Palermo Airport (PMO)plane CRL - PMO
- Take the train from Palermo Centrale to Caltanissetta Xirbitrain
- Take the train from Caltanissetta Xirbi to Comisotrain
12h 18m€100–302Train, train to Eindhoven Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Bruxelles-Central to Bredatrain
- Take the train from Breda to Eindhoven Centraaltrain
- Fly from Eindhoven Airport (EIN) to Catania–Fontanarossa Airport (CTA)plane EIN - CTA
- Take the bus from Catania Fontanarossa Airport Bus Stop to Gela Bus Stationbus
11h 33m€99–283Train
- Take the train from Brussel-Zuid / Bruxelles-Midi to Paris Nordtrain
- Take the train from Paris Gare De Lyon to Torino Porta Susatrain Tgv
- Take the train from Torino Porta di Susa to Roma Terminitrain
- Take the train from Roma Termini to Siracusatrain Ic
- Take the train from Siracusa to Comisotrain Re
29h 23m€331–818Bus, train
- Take the bus from Brussels-North train station to Milanbus
- Take the bus from Milano, Autostazione Lampugnano to Caltanissettabus
- Take the train from Caltanissetta C.Le to Comisotrain
39h 22m€196–341Train, night train
- Take the train from Brussel-Zuid / Bruxelles-Midi to Chambery Challes Les Eauxtrain
- Take the train from Chambery Challes Les Eaux to Milano Centraletrain Fr
- Take the night train from Milano Centrale to Siracusanighttrain Ini
- Take the train from Siracusa to Comisotrain Re
33h 10m€447–789
Brussels to Comiso by train and bus
Questions & Answers
The cheapest way to get from Brussels to Comiso is to bus and fly which costs €70 - €230 and takes 9h 33m.
The fastest way to get from Brussels to Comiso is to fly which takes 6h 29m and costs €120 - €400.
No, there is no direct bus from Brussels station to Comiso. However, there are services departing from Brussels-North Station and arriving at Comiso via Bologna Centrale and Gela. The journey, including transfers, takes approximately 36h 55m.
No, there is no direct train from Brussels to Comiso. However, there are services departing from Brussel-Zuid / Bruxelles-Midi and arriving at Comiso via Paris Nord, Paris Gare De Lyon, Torino Porta di Susa, Roma Termini and Siracusa. The journey, including transfers, takes approximately 29h 23m.
The distance between Brussels and Comiso is 1858 km.
The best way to get from Brussels to Comiso without a car is to train and bus which takes 25h 57m and costs €320 - €850.
It takes approximately 8h 49m to get from Brussels to Comiso, including transfers.
Brussels to Comiso bus services, operated by Pistoia viaggi, depart from Brussels-North Station.
Brussels to Comiso train services, operated by Eurostar, depart from Brussel-Zuid / Bruxelles-Midi station.
The best way to get from Brussels to Comiso is to bus which takes 36h 55m and costs . Alternatively, you can fly, which costs €120 - €400 and takes 6h 29m, you could also train, which costs €330 - €850 and takes 29h 23m.
What companies run services between Brussels, Belgium and Comiso, Italy?
You can take a bus from Brussels-North Station to Comiso via Bologna Centrale and Gela in around 36h 55m. Alternatively, Brussels Airlines, Aeroitalia, and FlexFlight ApS fly from Brussels Airport (BRU) to Vincenzo Magliocco Airport (CIY) twice daily.
- Website
- ryanair.com
Flights from Brussels Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h 30m
- When
- Sunday
- Estimated price
- €70–150
Flights from Brussels South Charleroi Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Monday, Tuesday, Wednesday, Friday, and Saturday
- Estimated price
- €50–190
Flights from Brussels South Charleroi Airport to Catania–Fontanarossa Airport via Milan Bergamo
- Ave. Duration
- 4h 52m
- When
- Tuesday, Friday, and Thursday
- Estimated price
- €50–190
Flights from Brussels South Charleroi Airport to Catania–Fontanarossa Airport via Pisa
- Ave. Duration
- 4h 55m
- When
- Friday
- Estimated price
- €50–190
Flights from Brussels South Charleroi Airport to Catania–Fontanarossa Airport via Verona
- Ave. Duration
- 5h 50m
- When
- Monday, Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- €50–190
Flights from Brussels South Charleroi Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- €50–210
Flights from Brussels South Charleroi Airport to Palermo Airport via Pisa
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- €50–210
Flights from Brussels South Charleroi Airport to Palermo Airport via Turin
- Ave. Duration
- 5h
- When
- Tuesday, Sunday, Wednesday, Friday, and Saturday
- Estimated price
- €50–210
Flights from Eindhoven Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- €65–210
Flights from Eindhoven Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h 25m
- When
- Sunday
- Estimated price
- €65–210
Flights from Eindhoven Airport to Catania–Fontanarossa Airport via Bologna
- Ave. Duration
- 4h 30m
- When
- Saturday
- Estimated price
- €65–210
Flights from Eindhoven Airport to Catania–Fontanarossa Airport via Milan Bergamo
- Ave. Duration
- 4h 45m
- When
- Sunday
- Estimated price
- €65–210
Flights from Eindhoven Airport to Catania–Fontanarossa Airport via Naples
- Ave. Duration
- 5h 25m
- When
- Monday and Thursday
- Estimated price
- €65–210
Flights from Eindhoven Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 6h 10m
- When
- Sunday
- Estimated price
- €65–210
- Website
- aeroitalia.com
Flights from Brussels Airport to Vincenzo Magliocco Airport via Rome
- Ave. Duration
- 4h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €100–390
Flights from Brussels Airport to Vincenzo Magliocco Airport via Bologna
- Ave. Duration
- 4h 30m
- When
- Monday and Friday
- Estimated price
- €230–1,000
Flights from Brussels Airport to Vincenzo Magliocco Airport via Milan Linate
- Ave. Duration
- 6h 30m
- When
- Monday to Saturday
- Estimated price
- €110–380
Flights from Brussels South Charleroi Airport to Vincenzo Magliocco Airport via Pisa
- Ave. Duration
- 7h 20m
- When
- Thursday and Sunday
- Estimated price
- €75–280
Flights from Brussels South Charleroi Airport to Vincenzo Magliocco Airport via Turin
- Ave. Duration
- 10h 10m
- When
- Monday and Friday
- Estimated price
- €120–1,100
- Website
- flexflight.dk
Flights from Brussels Airport to Vincenzo Magliocco Airport via Rome
- Ave. Duration
- 4h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €100–390
Flights from Brussels Airport to Vincenzo Magliocco Airport via Bologna
- Ave. Duration
- 4h 30m
- When
- Monday and Friday
- Estimated price
- €230–1,000
Flights from Brussels Airport to Vincenzo Magliocco Airport via Milan Linate
- Ave. Duration
- 6h 30m
- When
- Monday to Saturday
- Estimated price
- €110–380
Flights from Brussels South Charleroi Airport to Vincenzo Magliocco Airport via Pisa
- Ave. Duration
- 7h 20m
- When
- Thursday and Sunday
- Estimated price
- €75–280
Flights from Brussels South Charleroi Airport to Vincenzo Magliocco Airport via Turin
- Ave. Duration
- 10h 10m
- When
- Monday and Friday
- Estimated price
- €120–1,100
- Website
- ita-airways.com
Flights from Brussels Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- €80–240
Flights from Brussels Airport to Catania–Fontanarossa Airport via Milan Linate
- Ave. Duration
- 4h 30m
- When
- Monday to Friday
- Estimated price
- €80–190
- Website
- tuifly.be
Flights from Brussels Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 3h 5m
- When
- Wednesday and Saturday
- Estimated price
- €60–160
- Website
- brusselsairlines.com
Flights from Brussels Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- €85–240
- Website
- swiss.com
Flights from Brussels Airport to Catania–Fontanarossa Airport via Zurich
- Ave. Duration
- 4h 30m
- When
- Monday, Tuesday, Wednesday, Friday, and Sunday
- Estimated price
- €70–330
- Website
- volotea.com
Flights from Brussels South Charleroi Airport to Vincenzo Magliocco Airport via Verona
- Ave. Duration
- 4h 35m
- When
- Tuesday
- Estimated price
- €95–340
- Phone
- +44 (0)3432 186 186
- Website
- eurostar.com
Train from Brussel-Zuid / Bruxelles-Midi to Paris Nord
- Ave. Duration
- 1h 22m
- Frequency
- Every 20 minutes
- Estimated price
- €95–170
- Website
- https://www.eurostar.com/rw-en
Train from Brussel-Zuid / Bruxelles-Midi to Paris Nord
- Ave. Duration
- 1h 22m
- Frequency
- Every 20 minutes
- Estimated price
- €95–170
- Website
- https://www.eurostar.com/rw-en
Train from Brussel-Zuid / Bruxelles-Midi to Chambery Challes Les Eaux
- Ave. Duration
- 4h 29m
- Frequency
- 5 times a week
- Estimated price
- €260–440
- Website
- https://www.eurostar.com/rw-en
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact DetailsContact Details
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Brussel-Zuid / Bruxelles-Midi to Paris Nord
- Ave. Duration
- 3h 1m
- Frequency
- Every 4 hours
- Estimated price
- €50–110
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
Train from Brussel-Zuid / Bruxelles-Midi to Paris Nord
- Ave. Duration
- 3h 1m
- Frequency
- Every 4 hours
- Estimated price
- €50–110
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Paris Gare De Lyon to Torino Porta Susa
- Ave. Duration
- 5h 37m
- Frequency
- Every 4 hours
- Estimated price
- €150–250
- Website
- https://www.sncf-connect.com/en-en
Train from Paris Gare De Lyon to Torino Porta Susa
- Ave. Duration
- 5h 37m
- Frequency
- Every 4 hours
- Estimated price
- €150–250
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Paris Gare De Lyon to Torino Porta Susa
- Ave. Duration
- 5h 55m
- Frequency
- 4 times a day
- Estimated price
- €85–150
- Website
- https://www.trenitalia.com/en.html
Train from Palermo Centrale to Caltanissetta Xirbi
- Ave. Duration
- 1h 29m
- Frequency
- Every 2 hours
- Estimated price
- €15–26
- Website
- https://www.trenitalia.com/en.html
Train from Caltanissetta Xirbi to Comiso
- Ave. Duration
- 2h 12m
- Frequency
- 3 times a day
- Estimated price
- €19–35
- Website
- https://www.trenitalia.com/en.html
Train from Paris Gare De Lyon to Torino Porta Susa
- Ave. Duration
- 5h 55m
- Frequency
- 4 times a day
- Estimated price
- €85–150
- Website
- https://www.trenitalia.com/en.html
Train from Siracusa to Comiso
- Ave. Duration
- 2h 42m
- Frequency
- 3 times a day
- Estimated price
- €17–29
- Website
- https://www.trenitalia.com/en.html
Train from Caltanissetta C.Le to Comiso
- Ave. Duration
- 2h 2m
- Frequency
- Every 4 hours
- Estimated price
- €18–30
- Website
- https://www.trenitalia.com/en.html
Train from Chambery Challes Les Eaux to Milano Centrale
- Ave. Duration
- 3h 21m
- Frequency
- 4 times a day
- Estimated price
- €40–70
- Website
- https://www.trenitalia.com/en.html
Train from Siracusa to Comiso
- Ave. Duration
- 2h 42m
- Frequency
- 3 times a day
- Estimated price
- €17–29
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Torino Porta Susa to Villa S.Giovanni
- Ave. Duration
- 10h 25m
- Frequency
- 4 times a day
- Estimated price
- €200–390
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Torino Porta Susa to Villa S.Giovanni
- Ave. Duration
- 11h 37m
- Frequency
- Once daily
- Estimated price
- €170–340
- Website
- https://www.italotreno.it/en
Train from Torino Porta di Susa to Roma Termini
- Ave. Duration
- 4h 25m
- Frequency
- Hourly
- Estimated price
- €90–180
- Website
- https://www.italotreno.it/en
- Phone
- +32 70 79 79 79
- Website
- belgiantrain.be
Train from Bruxelles-Central to Breda
- Ave. Duration
- 1h 29m
- Frequency
- Hourly
- Estimated price
- €18–40
- Website
- https://www.belgiantrain.be/en
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Bruxelles-Central to Breda
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €12–25
- Website
- https://www.ns.nl/en
Train from Breda to Eindhoven Centraal
- Ave. Duration
- 39 min
- Frequency
- Every 30 minutes
- Estimated price
- €6–14
- Website
- https://www.ns.nl/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Siracusa
- Ave. Duration
- 11h 12m
- Frequency
- Twice daily
- Estimated price
- €85–190
- Website
- https://www.trenitalia.com/en.html
- Phone
- 06 3000
- Website
- trenitalia.com
Night train from Milano Centrale to Siracusa
- Ave. Duration
- 19h 38m
- Frequency
- Twice daily
- Estimated price
- €130–250
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 164160
- info@etnatrasporti.it
- Website
- etnatrasporti.it
Bus from Catania Fontanarossa Airport Bus Stop to Gela Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- €6–8
- Schedules at
- etnatrasporti.it
Bus from Catania Fontanarossa Airport Bus Stop to Gela Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- €6–8
- Schedules at
- etnatrasporti.it
Bus from Catania Fontanarossa Airport Bus Stop to Gela Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- €6–8
- Schedules at
- etnatrasporti.it
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Villa San Giovanni-Piazza Stazione to Gela Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- €9–14
- Schedules at
- autoservizisalemi.it
Bus from Bologna Centrale to Gela Bus Station
- Ave. Duration
- 16h 45m
- Frequency
- 5 times a week
- Estimated price
- €45–70
- Schedules at
- autoservizisalemi.it
- Phone
- +393293958604
- info@pistoiaviaggi.com
- Website
- pistoia-viaggi.it
Bus from Brussels-North Station to Bologna
- Ave. Duration
- 17h 10m
- Frequency
- Once a week
- Schedules at
- pistoia-viaggi.it
- info@flibco.com
- Website
- flibco.com
Bus from Brussels Midi / Brussels South West to Charleroi Airport
- Ave. Duration
- 55 min
- Frequency
- Every 30 minutes
- Estimated price
- €11–23
- Website
- https://www.flibco.com/en
Bus from Brussels Midi / Brussels South West to Charleroi Airport
- Ave. Duration
- 55 min
- Frequency
- Every 30 minutes
- Estimated price
- €11–23
- Website
- https://www.flibco.com/en
Bus from Brussels Midi / Brussels South West to Charleroi Airport
- Ave. Duration
- 55 min
- Frequency
- Every 30 minutes
- Estimated price
- €11–23
- Website
- https://www.flibco.com/en
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Brussels-North train station to Milan
- Ave. Duration
- 12h 25m
- Frequency
- Once daily
- Estimated price
- €65–120
- Website
- https://www.flixbus.co.uk
Bus from Milano, Autostazione Lampugnano to Caltanissetta
- Ave. Duration
- 22h 55m
- Frequency
- Once daily
- Estimated price
- €110–200
- Website
- https://www.flixbus.co.uk
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €95–150
- Website
- https://www.gnv.it/en
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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More Questions & Answers
Brussels to Comiso bus services, operated by Pistoia viaggi, arrive at Bologna station.
Brussels to Comiso train services, operated by Eurostar, arrive at Paris Nord station.
Book your Brussels to Comiso train tickets online with Omio.
There are 2016+ hotels available in Comiso.









































































