There are 10 ways to get from Brussels to Comiso by train, plane, train (TGV, Trenitalia), car, car ferry, bus, or train (Eurostar, TGV, Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Brussels South Charleroi Airport, fly to Vincenzo Magliocco Airport
best- Take the train from Bruxelles-Central to Luttretrain
- Fly from Brussels South Charleroi Airport (CRL) to Vincenzo Magliocco Airport (CIY)plane CRL - CIY
8h 46m€73–243Fly Brussels Airport to Vincenzo Magliocco Airport
cheapest- Fly from Brussels Airport (BRU) to Vincenzo Magliocco Airport (CIY)plane BRU - CIY
6h 36m€68–237Train via Rome
- Take the train from Brussel-Zuid to Chambérytrain
- Take the train from Chambery Challes Les Eaux to Torino Porta Susatrain Tgv
- Take the train from Torino Porta Susa to Roma Terminitrain Fr
- Take the train from Roma Termini to Siracusatrain Ic
- Take the train from Siracusa to Comisotrain Re
28h 16m€297–676Drive, car ferry
- Drive from Brussels to Port of Genoacar
- Take the car ferry from Port of Genoa to Port of Palermocarferry
- Drive from Port of Palermo to Comisocar
34h 31m€282–427Bus
- Take the bus from Brussels-North Station to Milano, Autostazione Lampugnanobus
- Take the bus from Milano, Autostazione Lampugnano to Cataniabus
- Take the bus from Catania Via Archimede to Ragusa Bus Terminalbus
37h 41mFly Brussels Airport to Catania–Fontanarossa Airport, bus
- Fly from Brussels Airport (BRU) to Catania–Fontanarossa Airport (CTA)plane BRU - CTA
- Take the bus from Aeroporto Vincenzo Bellini/Fontanarossa to Ragusa Bus Terminalbus
9h 13m€88–293Train to Brussels South Charleroi Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Bruxelles-Central to Luttretrain
- Fly from Brussels South Charleroi Airport (CRL) to Catania–Fontanarossa Airport (CTA)plane CRL - CTA
- Take the bus from Aeroporto Vincenzo Bellini/Fontanarossa to Ragusa Bus Terminalbus
10h 23m€73–179Train, train to Eindhoven Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Bruxelles-Central to Bredatrain
- Take the train from Breda to Eindhoventrain
- Fly from Eindhoven Airport (EIN) to Catania–Fontanarossa Airport (CTA)plane EIN - CTA
- Take the bus from Aeroporto Vincenzo Bellini/Fontanarossa to Ragusa Bus Terminalbus
12h 13m€90–319Train
- Take the train from Brussel-Zuid / Bruxelles-Midi to Chambery Challes Les Eauxtrain
- Take the train from Chambery Challes Les Eaux to Torino Porta Nuovatrain Tgv
- Take the train from Torino Porta Nuova to Siracusatrain
- Take the train from Siracusa to Comisotrain Re
35h 44m€475–808Bus via Palermo
- Take the bus from Brussels - Midi Train Station to Milano, Autostazione Lampugnanobus
- Take the bus from Milano, Autostazione Lampugnano to Palermobus
- Take the bus from Palermo to Comisobus
40h 50m
Brussels to Comiso by train
Questions & Answers
The cheapest way to get from Brussels to Comiso is to train and fly and bus which costs €70 - €180 and takes 10h 23m.
The fastest way to get from Brussels to Comiso is to fly which takes 6h 36m and costs €65 - €240.
No, there is no direct bus from Brussels station to Comiso. However, there are services departing from Brussels-North Station and arriving at Comiso via Milano, Autostazione Lampugnano, Catania Via Archimede and Ragusa. The journey, including transfers, takes approximately 37h 41m.
No, there is no direct train from Brussels to Comiso. However, there are services departing from Brussel-Zuid and arriving at Comiso via Chambery Challes Les Eaux, Torino Porta Susa, Roma Termini and Siracusa. The journey, including transfers, takes approximately 28h 16m.
The distance between Brussels and Comiso is 1762 km.
The best way to get from Brussels to Comiso without a car is to train via Rome which takes 28h 16m and costs €290 - €700.
It takes approximately 8h 46m to get from Brussels to Comiso, including transfers.
Brussels to Comiso bus services, operated by Pistoia viaggi, depart from Brussels-North Station.
Brussels to Comiso train services, operated by Nederlandse Spoorwegen (NS), depart from Brussel-Zuid station.
The best way to get from Brussels to Comiso is to train via Rome which takes 28h 16m and costs €290 - €700. Alternatively, you can bus, which costs and takes 37h 41m, you could also fly, which costs €65 - €240 and takes 6h 36m.
What companies run services between Brussels, Belgium and Comiso, Italy?
You can take a train from Brussel-Zuid to Comiso via Chambéry, Chambery Challes Les Eaux, Torino Porta Susa, Roma Termini, and Siracusa in around 28h 16m. Alternatively, you can take a bus from Brussels-North Station to Comiso via Milano, Autostazione Lampugnano, Catania, Catania Via Archimede, and Ragusa in around 37h 41m.
- Website
- ryanair.com
Flights from Brussels Airport to Catania–Fontanarossa Airport via Pisa
- Ave. Duration
- 4h 20m
- When
- Tuesday
- Estimated price
- €75–270
Flights from Brussels Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h 37m
- When
- Monday and Sunday
- Estimated price
- €75–270
Flights from Brussels South Charleroi Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- €50–140
Flights from Brussels South Charleroi Airport to Catania–Fontanarossa Airport via Verona
- Ave. Duration
- 6h 20m
- When
- Monday, Tuesday, Thursday, and Sunday
- Estimated price
- €50–140
Flights from Eindhoven Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 3h
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- €55–230
Flights from Eindhoven Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h 30m
- When
- Sunday
- Estimated price
- €55–230
Flights from Eindhoven Airport to Catania–Fontanarossa Airport via Milan Bergamo
- Ave. Duration
- 4h 35m
- When
- Friday
- Estimated price
- €55–230
Flights from Eindhoven Airport to Catania–Fontanarossa Airport via Bologna
- Ave. Duration
- 4h 35m
- When
- Monday and Sunday
- Estimated price
- €55–230
Flights from Eindhoven Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 5h 55m
- When
- Sunday
- Estimated price
- €55–230
Flights from Eindhoven Airport to Catania–Fontanarossa Airport via Naples
- Ave. Duration
- 6h 15m
- When
- Monday
- Estimated price
- €55–230
Flights from Eindhoven Airport to Catania–Fontanarossa Airport via Pisa
- Ave. Duration
- 6h 25m
- When
- Monday, Friday, and Sunday
- Estimated price
- €55–230
- Website
- aeroitalia.com
Flights from Brussels South Charleroi Airport to Vincenzo Magliocco Airport via Turin
- Ave. Duration
- 5h 10m
- When
- Monday
- Estimated price
- €110–360
Flights from Brussels South Charleroi Airport to Vincenzo Magliocco Airport via Bologna
- Ave. Duration
- 10h
- When
- Monday
- Estimated price
- €110–360
Flights from Brussels South Charleroi Airport to Vincenzo Magliocco Airport via Pisa
- Ave. Duration
- 10h 30m
- When
- Thursday and Sunday
- Estimated price
- €55–210
Flights from Brussels Airport to Vincenzo Magliocco Airport via Rome
- Ave. Duration
- 4h 15m
- When
- Monday, Friday, and Sunday
- Estimated price
- €55–220
Flights from Brussels Airport to Vincenzo Magliocco Airport via Bologna
- Ave. Duration
- 4h 30m
- When
- Monday and Friday
- Estimated price
- €140–220
Flights from Brussels Airport to Vincenzo Magliocco Airport via Milan Linate
- Ave. Duration
- 6h 20m
- When
- Saturday
- Estimated price
- €120–380
- Website
- flexflight.dk
Flights from Brussels South Charleroi Airport to Vincenzo Magliocco Airport via Turin
- Ave. Duration
- 5h 10m
- When
- Monday
- Estimated price
- €110–360
Flights from Brussels South Charleroi Airport to Vincenzo Magliocco Airport via Bologna
- Ave. Duration
- 10h
- When
- Monday
- Estimated price
- €110–360
Flights from Brussels South Charleroi Airport to Vincenzo Magliocco Airport via Pisa
- Ave. Duration
- 10h 30m
- When
- Thursday and Sunday
- Estimated price
- €55–210
Flights from Brussels Airport to Vincenzo Magliocco Airport via Rome
- Ave. Duration
- 4h 15m
- When
- Monday, Friday, and Sunday
- Estimated price
- €55–220
Flights from Brussels Airport to Vincenzo Magliocco Airport via Bologna
- Ave. Duration
- 4h 30m
- When
- Monday and Friday
- Estimated price
- €140–220
Flights from Brussels Airport to Vincenzo Magliocco Airport via Milan Linate
- Ave. Duration
- 6h 20m
- When
- Saturday
- Estimated price
- €120–380
- Website
- ita-airways.com
Flights from Brussels Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- €60–250
Flights from Brussels Airport to Catania–Fontanarossa Airport via Milan Linate
- Ave. Duration
- 4h 40m
- When
- Monday to Friday
- Estimated price
- €75–250
- Website
- brusselsairlines.com
Flights from Brussels Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 45m
- When
- Tuesday, Saturday, and Sunday
- Estimated price
- €60–250
Flights from Brussels Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h 40m
- When
- Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €60–250
- Website
- flyulendo.com
Flights from Brussels South Charleroi Airport to Vincenzo Magliocco Airport via Tirana
- Ave. Duration
- 10h 25m
- When
- Monday and Friday
- Estimated price
- €50–210
- Website
- tuifly.be
Flights from Brussels Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 3h 5m
- When
- Saturday
- Estimated price
- €70–250
- Website
- easyjet.com
Flights from Brussels Airport to Catania–Fontanarossa Airport via Geneva
- Ave. Duration
- 5h 15m
- When
- Wednesday
- Estimated price
- €75–190
- Phone
- +32 70 79 79 79
- Website
- belgiantrain.be
Train from Bruxelles-Central to Luttre
- Ave. Duration
- 43 min
- Frequency
- Every 20 minutes
- Estimated price
- €9–17
- Website
- https://www.belgiantrain.be/en
Train from Bruxelles-Central to Breda
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €23–45
- Website
- https://www.belgiantrain.be/en
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Brussel-Zuid to Chambéry
- Ave. Duration
- 3h 55m
- Frequency
- 3 times a week
- Estimated price
- €80–210
- Website
- https://www.ns.nl/en
Train from Bruxelles-Central to Breda
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–27
- Website
- https://www.ns.nl/en
Train from Breda to Eindhoven
- Ave. Duration
- 39 min
- Frequency
- Every 30 minutes
- Estimated price
- €6–15
- Website
- https://www.ns.nl/en
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Chambery Challes Les Eaux to Torino Porta Susa
- Ave. Duration
- 2h 39m
- Frequency
- 3 times a day
- Estimated price
- €35–65
- Website
- https://www.sncf-connect.com/en-en
Train from Chambery Challes Les Eaux to Torino Porta Nuova
- Ave. Duration
- 2h 41m
- Frequency
- 4 times a week
- Estimated price
- €35–65
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Chambery Challes Les Eaux to Torino Porta Susa
- Ave. Duration
- 2h 34m
- Frequency
- Twice daily
- Estimated price
- €25–45
- Website
- https://www.trenitalia.com/en.html
Train from Siracusa to Comiso
- Ave. Duration
- 2h 34m
- Frequency
- 3 times a day
- Estimated price
- €18–30
- Website
- https://www.trenitalia.com/en.html
Train from Torino Porta Nuova to Siracusa
- Ave. Duration
- 23h 8m
- Frequency
- Once a week
- Estimated price
- €190–330
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Torino Porta Susa to Roma Termini
- Ave. Duration
- 4h 15m
- Frequency
- Hourly
- Estimated price
- €100–190
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Torino Porta Susa to Roma Termini
- Ave. Duration
- 4h 49m
- Frequency
- 4 times a day
- Estimated price
- €90–180
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Siracusa
- Ave. Duration
- 11h 12m
- Frequency
- Once daily
- Estimated price
- €80–190
- Website
- https://www.trenitalia.com/en.html
- Phone
- +44 343 218 6186
- Website
- eurostar.com
Train from Brussel-Zuid / Bruxelles-Midi to Chambery Challes Les Eaux
- Ave. Duration
- 4h 21m
- Frequency
- Twice a week
- Estimated price
- €230–390
- Website
- https://www.eurostar.com/rw-en
- Phone
- +393293958604
- info@pistoiaviaggi.com
- Website
- pistoia-viaggi.it
Bus from Brussels-North Station to Milano, Autostazione Lampugnano
- Ave. Duration
- 13h 33m
- Frequency
- Once a week
- Schedules at
- pistoia-viaggi.it
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Milano, Autostazione Lampugnano to Catania
- Ave. Duration
- 18h 55m
- Frequency
- Twice daily
- Estimated price
- €85–150
- Website
- https://www.flixbus.co.uk
Bus from Milano, Autostazione Lampugnano to Palermo
- Ave. Duration
- 21h 55m
- Frequency
- Once daily
- Estimated price
- €100–180
- Website
- https://www.flixbus.co.uk
- Phone
- +39 0935 22 460
- Website
- interbus.it
Bus from Catania Via Archimede to Ragusa Bus Terminal
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €6–13
- Schedules at
- interbus.it
Bus from Aeroporto Vincenzo Bellini/Fontanarossa to Ragusa Bus Terminal
- Ave. Duration
- 1h 40m
- Frequency
- Hourly
- Estimated price
- €6–12
- Schedules at
- interbus.it
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Brussels - Midi Train Station to Milano, Autostazione Lampugnano
- Ave. Duration
- 13h 20m
- Frequency
- Twice daily
- Estimated price
- €55–110
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +39 091 62.08.111
- info@astsicilia.it
- Website
- aziendasicilianatrasporti.it
Bus from Palermo to Comiso
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Schedules at
- aziendasicilianatrasporti.it
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €95–150
- Website
- https://www.gnv.it/en
Want to know more about travelling around Italy
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More Questions & Answers
Brussels to Comiso bus services, operated by Pistoia viaggi, arrive at Milano, Autostazione Lampugnano station.
Brussels to Comiso train services, operated by Nederlandse Spoorwegen (NS), arrive at Chambéry station.
Book your Brussels to Comiso train tickets online with Omio.
There are 1865+ hotels available in Comiso.





























































