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How to get fromBrussels to Comisoby train, plane, train (TGV, Trenitalia), car, car ferry, bus or train (Eurostar, TGV, Trenitalia)

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There are 10 ways to get from Brussels to Comiso by train, plane, train (TGV, Trenitalia), car, car ferry, bus, or train (Eurostar, TGV, Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Brussels South Charleroi Airport, fly to Vincenzo Magliocco Airport

    best
    1. Take the train from Bruxelles-Central to Luttretrain train
    2. Fly from Brussels South Charleroi Airport (CRL) to Vincenzo Magliocco Airport (CIY)plane plane CRL - CIY
    8h 46m
    €73–243
  2. Fly Brussels Airport to Vincenzo Magliocco Airport

    cheapest
    1. Fly from Brussels Airport (BRU) to Vincenzo Magliocco Airport (CIY)plane plane BRU - CIY
    6h 36m
    €68–237
  3. Train via Rome

    1. Take the train from Brussel-Zuid to Chambérytrain train
    2. Take the train from Chambery Challes Les Eaux to Torino Porta Susatrain train Tgv
    3. Take the train from Torino Porta Susa to Roma Terminitrain train Fr
    4. Take the train from Roma Termini to Siracusatrain train Ic
    5. Take the train from Siracusa to Comisotrain train Re
    28h 16m
    €297–676
  4. Drive, car ferry

    1. Drive from Brussels to Port of Genoacar car
    2. Take the car ferry from Port of Genoa to Port of Palermocarferry car ferry
    3. Drive from Port of Palermo to Comisocar car
    34h 31m
    €282–427
  5. Bus

    1. Take the bus from Brussels-North Station to Milano, Autostazione Lampugnanobus bus
    2. Take the bus from Milano, Autostazione Lampugnano to Cataniabus bus
    3. Take the bus from Catania Via Archimede to Ragusa Bus Terminalbus bus
    37h 41m
  6. Fly Brussels Airport to Catania–Fontanarossa Airport, bus

    1. Fly from Brussels Airport (BRU) to Catania–Fontanarossa Airport (CTA)plane plane BRU - CTA
    2. Take the bus from Aeroporto Vincenzo Bellini/Fontanarossa to Ragusa Bus Terminalbus bus
    9h 13m
    €88–293
  7. Train to Brussels South Charleroi Airport, fly to Catania–Fontanarossa Airport, bus

    1. Take the train from Bruxelles-Central to Luttretrain train
    2. Fly from Brussels South Charleroi Airport (CRL) to Catania–Fontanarossa Airport (CTA)plane plane CRL - CTA
    3. Take the bus from Aeroporto Vincenzo Bellini/Fontanarossa to Ragusa Bus Terminalbus bus
    10h 23m
    €73–179
  8. Train, train to Eindhoven Airport, fly to Catania–Fontanarossa Airport, bus

    1. Take the train from Bruxelles-Central to Bredatrain train
    2. Take the train from Breda to Eindhoventrain train
    3. Fly from Eindhoven Airport (EIN) to Catania–Fontanarossa Airport (CTA)plane plane EIN - CTA
    4. Take the bus from Aeroporto Vincenzo Bellini/Fontanarossa to Ragusa Bus Terminalbus bus
    12h 13m
    €90–319
  9. Train

    1. Take the train from Brussel-Zuid / Bruxelles-Midi to Chambery Challes Les Eauxtrain train
    2. Take the train from Chambery Challes Les Eaux to Torino Porta Nuovatrain train Tgv
    3. Take the train from Torino Porta Nuova to Siracusatrain train
    4. Take the train from Siracusa to Comisotrain train Re
    35h 44m
    €475–808
  10. Bus via Palermo

    1. Take the bus from Brussels - Midi Train Station to Milano, Autostazione Lampugnanobus bus
    2. Take the bus from Milano, Autostazione Lampugnano to Palermobus bus
    3. Take the bus from Palermo to Comisobus bus
    40h 50m

Brussels to Comiso by train

Calendar3Weekly Trains
Duration28h 16mAverage Duration
Ticket€297Cheapest Price
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Questions & Answers

What companies run services between Brussels, Belgium and Comiso, Italy?

You can take a train from Brussel-Zuid to Comiso via Chambéry, Chambery Challes Les Eaux, Torino Porta Susa, Roma Termini, and Siracusa in around 28h 16m. Alternatively, you can take a bus from Brussels-North Station to Comiso via Milano, Autostazione Lampugnano, Catania, Catania Via Archimede, and Ragusa in around 37h 41m.

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