There are 11 ways to get from Brussels to Comiso by bus, plane, train, car, car ferry, train (Trenitalia), or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Brussels South Charleroi Airport, fly to Vincenzo Magliocco Airport
best- Take the bus from Brussels Midi / Brussels South West to Charleroi Airportbus
- Fly from Brussels South Charleroi Airport (CRL) to Vincenzo Magliocco Airport (CIY)plane CRL - CIY
7h 43m€80–269Bus to Brussels South Charleroi Airport, fly to Catania–Fontanarossa Airport, bus
cheapest- Take the bus from Brussels Midi / Brussels South West to Charleroi Airportbus
- Fly from Brussels South Charleroi Airport (CRL) to Catania–Fontanarossa Airport (CTA)plane CRL - CTA
- Take the bus from Aeroporto Vincenzo Bellini/Fontanarossa to Ragusa Bus Terminalbus
9h 50m€72–192Train, bus
- Take the train from Brussel-Zuid to Paris Nordtrain
- Take the train from Paris Gare De Lyon to Torino Porta Susatrain Tgv
- Take the train from Torino Porta Susa to Villa S.Giovannitrain Fr
- Take the bus from Villa San Giovanni-Piazza Stazione to Gela Bus Stationbus
26h 10m€308–729Drive, car ferry
- Drive from Brussels to Port of Genoacar
- Take the car ferry from Port of Genoa to Port of Palermocarferry
- Drive from Port of Palermo to Comisocar
34h 33m€277–416Bus
- Take the bus from Brussels-North Station to Bolognabus
- Take the bus from Bologna Centrale to Gela Bus Stationbus Autoservizi Salemi S121 / ...
36h 55mFly Brussels Airport to Catania–Fontanarossa Airport, bus
- Fly from Brussels Airport (BRU) to Catania–Fontanarossa Airport (CTA)plane BRU - CTA
- Take the bus from Aeroporto Vincenzo Bellini/Fontanarossa to Ragusa Bus Terminalbus
9h 6m€87–203Fly Brussels Airport to Vincenzo Magliocco Airport
- Fly from Brussels Airport (BRU) to Vincenzo Magliocco Airport (CIY)plane BRU - CIY
6h 29m€145–820Bus to Brussels South Charleroi Airport, fly to Palermo Airport, train
- Take the bus from Brussels Midi / Brussels South West to Charleroi Airportbus
- Fly from Brussels South Charleroi Airport (CRL) to Palermo Airport (PMO)plane CRL - PMO
- Take the train from Palermo Centrale to Caltanissetta Xirbitrain
- Take the train from Caltanissetta Xirbi to Comisotrain
12h 27m€100–262Train
- Take the train from Brussel-Zuid to Paris Nordtrain
- Take the train from Paris Gare De Lyon to Milano Centraletrain Fr
- Take the train from Milano Centrale to Roma Terminitrain Fr / ...
- Take the train from Roma Termini to Siracusatrain Ic
- Take the train from Siracusa to Comisotrain Re
28h 30m€317–636Bus via Aosta
- Take the bus from Brussels-North train station to Aostabus
- Take the bus from Aosta to Cataniabus
- Take the bus from Catania to Comisobus
40h 33m€183–323Train, night train
- Take the train from Brussel-Zuid / Bruxelles-Midi to Marne La Vallee Chessytrain Tgv
- Take the train from Marne La Vallee Chessy to Milano Centraletrain Fr
- Take the night train from Milano Centrale to Siracusanighttrain Ini
- Take the train from Siracusa to Comisotrain Re
34h 15m€316–638
Brussels to Comiso by train and bus
Questions & Answers
The cheapest way to get from Brussels to Comiso is to bus and fly which costs €70 - €200 and takes 9h 50m.
The fastest way to get from Brussels to Comiso is to fly which takes 6h 29m and costs €140 - €850.
No, there is no direct bus from Brussels station to Comiso. However, there are services departing from Brussels-North Station and arriving at Comiso via Bologna Centrale and Gela. The journey, including transfers, takes approximately 36h 55m.
No, there is no direct train from Brussels to Comiso. However, there are services departing from Brussel-Zuid and arriving at Comiso via Paris Nord, Paris Gare De Lyon, Milano Centrale, Roma Termini and Siracusa. The journey, including transfers, takes approximately 28h 30m.
The distance between Brussels and Comiso is 1763 km.
The best way to get from Brussels to Comiso without a car is to train and bus which takes 26h 10m and costs €300 - €750.
It takes approximately 7h 43m to get from Brussels to Comiso, including transfers.
Brussels to Comiso bus services, operated by FlixBus, depart from Brussels-North train station.
Brussels to Comiso train services, operated by Nederlandse Spoorwegen (NS), depart from Brussel-Zuid station.
The best way to get from Brussels to Comiso is to bus which takes 36h 55m and costs . Alternatively, you can fly, which costs €140 - €850 and takes 6h 29m, you could also train, which costs €310 - €650 and takes 28h 30m.
What companies run services between Brussels, Belgium and Comiso, Italy?
You can take a bus from Brussels-North Station to Comiso via Bologna Centrale and Gela in around 36h 55m. Alternatively, Brussels Airlines, FlexFlight ApS, and Aeroitalia fly from Brussels Airport (BRU) to Vincenzo Magliocco Airport (CIY) twice daily.
- Website
- ryanair.com
Flights from Brussels Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h 25m
- When
- Friday
- Estimated price
- €70–190
Flights from Brussels South Charleroi Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Monday, Tuesday, Wednesday, Friday, and Saturday
- Estimated price
- €50–150
Flights from Brussels South Charleroi Airport to Catania–Fontanarossa Airport via Pisa
- Ave. Duration
- 4h 55m
- When
- Friday
- Estimated price
- €50–150
Flights from Brussels South Charleroi Airport to Catania–Fontanarossa Airport via Verona
- Ave. Duration
- 5h 50m
- When
- Monday, Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- €50–150
Flights from Brussels South Charleroi Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- €45–170
Flights from Brussels South Charleroi Airport to Palermo Airport via Pisa
- Ave. Duration
- 5h 10m
- When
- Monday, Tuesday, Wednesday, Friday, and Saturday
- Estimated price
- €45–170
- Website
- aeroitalia.com
Flights from Brussels South Charleroi Airport to Vincenzo Magliocco Airport via Turin
- Ave. Duration
- 10h 10m
- When
- Monday and Friday
- Estimated price
- €90–650
Flights from Brussels Airport to Vincenzo Magliocco Airport via Rome
- Ave. Duration
- 4h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €85–350
Flights from Brussels Airport to Vincenzo Magliocco Airport via Milan Linate
- Ave. Duration
- 6h 30m
- When
- Monday to Saturday
- Estimated price
- €100–350
- Website
- flexflight.dk
Flights from Brussels South Charleroi Airport to Vincenzo Magliocco Airport via Turin
- Ave. Duration
- 10h 10m
- When
- Monday and Friday
- Estimated price
- €90–650
Flights from Brussels Airport to Vincenzo Magliocco Airport via Rome
- Ave. Duration
- 4h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €85–350
Flights from Brussels Airport to Vincenzo Magliocco Airport via Milan Linate
- Ave. Duration
- 6h 30m
- When
- Monday to Saturday
- Estimated price
- €100–350
- Website
- ita-airways.com
Flights from Brussels Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- €75–230
Flights from Brussels Airport to Catania–Fontanarossa Airport via Milan Linate
- Ave. Duration
- 4h 30m
- When
- Monday to Friday
- Estimated price
- €75–180
- Website
- brusselsairlines.com
Flights from Brussels Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- €75–230
Flights from Brussels Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h 25m
- When
- Monday to Friday
- Estimated price
- €75–230
- Website
- flyulendo.com
Flights from Brussels South Charleroi Airport to Vincenzo Magliocco Airport via Tirana
- Ave. Duration
- 10h 20m
- When
- Monday and Friday
- Estimated price
- €55–230
- Website
- volotea.com
Flights from Brussels South Charleroi Airport to Vincenzo Magliocco Airport via Verona
- Ave. Duration
- 4h 40m
- When
- Tuesday
- Estimated price
- €75–280
- Website
- tuifly.be
Flights from Brussels Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 3h 5m
- When
- Wednesday and Saturday
- Estimated price
- €55–180
- Website
- swiss.com
Flights from Brussels Airport to Catania–Fontanarossa Airport via Zurich
- Ave. Duration
- 4h 30m
- When
- Monday, Tuesday, Wednesday, Friday, and Sunday
- Estimated price
- €180–420
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Brussel-Zuid to Paris Nord
- Ave. Duration
- 1h 22m
- Frequency
- Every 2 hours
- Estimated price
- €30–75
- Website
- https://www.ns.nl/en
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Paris Gare De Lyon to Torino Porta Susa
- Ave. Duration
- 5h 37m
- Frequency
- 3 times a day
- Estimated price
- €140–240
- Website
- https://www.sncf-connect.com/en-en
Train from Brussel-Zuid / Bruxelles-Midi to Marne La Vallee Chessy
- Ave. Duration
- 1h 58m
- Frequency
- Every 3 hours
- Estimated price
- €65–110
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Paris Gare De Lyon to Torino Porta Susa
- Ave. Duration
- 5h 55m
- Frequency
- Twice daily
- Estimated price
- €90–150
- Website
- https://www.trenitalia.com/en.html
Train from Palermo Centrale to Caltanissetta Xirbi
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- €15–26
- Website
- https://www.trenitalia.com/en.html
Train from Caltanissetta Xirbi to Comiso
- Ave. Duration
- 2h 12m
- Frequency
- Twice daily
- Estimated price
- €19–35
- Website
- https://www.trenitalia.com/en.html
Train from Paris Gare De Lyon to Milano Centrale
- Ave. Duration
- 6h 42m
- Frequency
- Twice daily
- Estimated price
- €110–180
- Website
- https://www.trenitalia.com/en.html
Train from Siracusa to Comiso
- Ave. Duration
- 2h 34m
- Frequency
- 3 times a day
- Estimated price
- €17–29
- Website
- https://www.trenitalia.com/en.html
Train from Marne La Vallee Chessy to Milano Centrale
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a week
- Estimated price
- €100–180
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Torino Porta Susa to Villa S.Giovanni
- Ave. Duration
- 10h 39m
- Frequency
- Twice daily
- Estimated price
- €200–390
- Schedules at
- trenitalia.com
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €80–160
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Torino Porta Susa to Villa S.Giovanni
- Ave. Duration
- 11h 37m
- Frequency
- Once daily
- Estimated price
- €170–350
- Website
- https://www.italotreno.it/en
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 4h 42m
- Frequency
- Once daily
- Estimated price
- €70–150
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Siracusa
- Ave. Duration
- 11h 12m
- Frequency
- Once daily
- Estimated price
- €85–190
- Website
- https://www.trenitalia.com/en.html
- Phone
- +44 343 218 6186
- Website
- eurostar.com
Train from Brussel-Zuid / Bruxelles-Midi to Marne La Vallee Chessy
- Ave. Duration
- 1h 32m
- Frequency
- 4 times a week
- Estimated price
- €110–180
- Website
- https://www.eurostar.com/rw-en
- Phone
- 06 3000
- Website
- trenitalia.com
Night train from Milano Centrale to Siracusa
- Ave. Duration
- 19h 38m
- Frequency
- Once daily
- Estimated price
- €130–250
- Website
- https://www.trenitalia.com/en.html
- info@flibco.com
- Website
- flibco.com
Bus from Brussels Midi / Brussels South West to Charleroi Airport
- Ave. Duration
- 55 min
- Frequency
- Every 30 minutes
- Estimated price
- €11–23
- Website
- https://www.flibco.com/en
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Villa San Giovanni-Piazza Stazione to Gela Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- €9–14
- Schedules at
- autoservizisalemi.it
Bus from Bologna Centrale to Gela Bus Station
- Ave. Duration
- 16h 45m
- Frequency
- 5 times a week
- Estimated price
- €45–70
- Schedules at
- autoservizisalemi.it
- Phone
- +393293958604
- info@pistoiaviaggi.com
- Website
- pistoia-viaggi.it
Bus from Brussels-North Station to Bologna
- Ave. Duration
- 17h 10m
- Frequency
- Once a week
- Schedules at
- pistoia-viaggi.it
- Phone
- +39 0935 22 460
- Website
- interbus.it
Bus from Aeroporto Vincenzo Bellini/Fontanarossa to Ragusa Bus Terminal
- Ave. Duration
- 1h 40m
- Frequency
- Hourly
- Estimated price
- €6–12
- Schedules at
- interbus.it
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Brussels-North train station to Aosta
- Ave. Duration
- 12h 20m
- Frequency
- Once daily
- Estimated price
- €60–110
- Website
- https://www.flixbus.co.uk
Bus from Aosta to Catania
- Ave. Duration
- 22h 40m
- Frequency
- Once daily
- Estimated price
- €110–200
- Website
- https://www.flixbus.co.uk
Bus from Catania to Comiso
- Ave. Duration
- 3h 33m
- Frequency
- Once daily
- Estimated price
- €12–21
- Website
- https://www.flixbus.co.uk
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €90–140
- Website
- https://www.gnv.it/en
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More Questions & Answers
Brussels to Comiso bus services, operated by FlixBus, arrive at Aosta station.
Brussels to Comiso train services, operated by Nederlandse Spoorwegen (NS), arrive at Paris Nord station.
Book your Brussels to Comiso train tickets online with Omio.
Book your Brussels to Comiso bus tickets online with FlixBus.
There are 1972+ hotels available in Comiso.































































