There are 14 ways to get from Brussels to Comiso by plane, bus, train, car, car ferry, busferry, taxi, train (Eurostar, Trenitalia), or train (Eurostar, TGV)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Brussels Airport to Catania–Fontanarossa Airport, bus
best- Fly from Brussels Airport (BRU) to Catania–Fontanarossa Airport (CTA)BRU - CTA
- Take the bus from Catania Fontanarossa Airport Bus Stop to Gela Bus Station
8h 36m€94–273Bus to Brussels South Charleroi Airport, fly to Catania–Fontanarossa Airport, bus
cheapest- Take the bus from Brussels Midi / Brussels South West to Charleroi Airport
- Fly from Brussels South Charleroi Airport (CRL) to Catania–Fontanarossa Airport (CTA)CRL - CTA
- Take the bus from Catania Fontanarossa Airport Bus Stop to Gela Bus Station
9h 20m€86–214Train, bus
- Take the train from Brussel-Zuid / Bruxelles-Midi to Aeroport Cdg2 Tgv RoissyTgv
- Take the train from Aeroport Cdg2 Tgv Roissy to Torino Porta SusaTgv
- Take the train from Torino Porta Susa to Villa S.GiovanniFr
- Take the bus from Villa San Giovanni-Piazza Stazione to Gela Bus Station
26h 24m€270–744Drive, car ferry
- Drive from Brussels to Port of Genoa
- Take the car ferry from Port of Genoa to Port of Palermo
- Drive from Port of Palermo to Comiso
34h 27m€245–414Bus
- Take the bus from Brussels-North Station to Bologna
- Take the bus from Bologna Centrale to Gela Bus StationAutoservizi Salemi S121 / ...
36h 55mFly Brussels Airport to Vincenzo Magliocco Airport
- Fly from Brussels Airport (BRU) to Vincenzo Magliocco Airport (CIY)BRU - CIY
7h 44m€119–412Fly Brussels Airport to Malta International Airport, bus and ferry, taxi
- Fly from Brussels Airport (BRU) to Malta International Airport (MLA)BRU - MLA
- Take the busferry from Valletta to Pozzallo
- Take the taxi from Pozzallo to Comiso
9h 45m€257–411Bus to Brussels South Charleroi Airport, fly to Malta International Airport, bus and ferry, taxi
- Take the bus from Brussels Midi / Brussels South West to Charleroi Airport
- Fly from Brussels South Charleroi Airport (CRL) to Malta International Airport (MLA)CRL - MLA
- Take the busferry from Valletta to Pozzallo
- Take the taxi from Pozzallo to Comiso
10h 23m€254–392Train to Amsterdam Airport Schiphol, fly to Catania–Fontanarossa Airport, bus
- Take the train from Brussel-Zuid / Bruxelles-Midi to Schiphol Airport
- Fly from Amsterdam Airport Schiphol (AMS) to Catania–Fontanarossa Airport (CTA)AMS - CTA
- Take the bus from Catania Fontanarossa Airport Bus Stop to Gela Bus Station
10h 12m€119–382Bus to Brussels South Charleroi Airport, fly to Palermo Airport, train
- Take the bus from Brussels Midi / Brussels South West to Charleroi Airport
- Fly from Brussels South Charleroi Airport (CRL) to Palermo Airport (PMO)CRL - PMO
- Take the train from Palermo Centrale to Caltanissetta Xirbi
- Take the train from Caltanissetta Xirbi to Comiso
12h 27m€88–314Train, train to Eindhoven Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Bruxelles-Central to Breda
- Take the train from Breda to Eindhoven
- Fly from Eindhoven Airport (EIN) to Catania–Fontanarossa Airport (CTA)EIN - CTA
- Take the bus from Catania Fontanarossa Airport Bus Stop to Gela Bus Station
11h 39m€114–346Train via Naples
- Take the train from Brussel-Zuid / Bruxelles-Midi to Paris Nord
- Take the train from Paris Gare De Lyon to Milano CentraleFr
- Take the train from Milano Centrale to Napoli Centrale
- Take the train from Napoli Centrale to SiracusaIc
- Take the train from Siracusa to ComisoRe
27h 58m€202–535Train
- Take the train from Brussel-Zuid / Bruxelles-Midi to Chambery Challes Les Eaux
- Take the train from Chambery Challes Les Eaux to Torino Porta NuovaTgv
- Take the train from Torino Porta Nuova to Siracusa
- Take the train from Siracusa to ComisoRe
34h 46m€270–595Bus via Milan
- Take the bus from Brussels-North train station to Milano, Autostazione Lampugnano
- Take the bus from Milano, Autostazione Lampugnano to Catania Airport
- Take the bus from Catania Airport to Comiso
37h 38m€113–328
Brussels to Comiso by train and bus
Questions & Answers
The cheapest way to get from Brussels to Comiso is to bus and fly which costs €85 - €220 and takes 9h 20m.
The fastest way to get from Brussels to Comiso is to fly which takes 7h 44m and costs €110 - €420.
No, there is no direct bus from Brussels station to Comiso. However, there are services departing from Brussels-North Station and arriving at Comiso via Bologna Centrale and Gela. The journey, including transfers, takes approximately 36h 55m.
No, there is no direct train from Brussels to Comiso. However, there are services departing from Brussel-Zuid / Bruxelles-Midi and arriving at Comiso via Paris Nord, Paris Gare De Lyon, Milano Centrale, Napoli Centrale and Siracusa. The journey, including transfers, takes approximately 27h 58m.
The distance between Brussels and Comiso is 1858 km.
The best way to get from Brussels to Comiso without a car is to train and bus which takes 26h 24m and costs €270 - €750.
It takes approximately 8h 36m to get from Brussels to Comiso, including transfers.
Brussels to Comiso bus services, operated by FlixBus, depart from Brussels-North train station.
Brussels to Comiso train services, operated by Eurostar, depart from Brussel-Zuid / Bruxelles-Midi station.
The best way to get from Brussels to Comiso is to bus which takes 36h 55m and costs . Alternatively, you can fly, which costs €110 - €420 and takes 7h 44m, you could also train via Naples, which costs €200 - €550 and takes 27h 58m.
What companies run services between Brussels, Belgium and Comiso, Italy?
You can take a bus from Brussels-North Station to Comiso via Bologna Centrale and Gela in around 36h 55m. Alternatively, TUI fly Belgium, Ulendo Airlink, and three other airlines fly from Brussels Airport (BRU) to Vincenzo Magliocco Airport (CIY) twice daily.
- Website
- ryanair.com
Flights from Brussels Airport to Catania–Fontanarossa Airport via Pisa
- Ave. Duration
- 4h 20m
- When
- Tuesday
- Estimated price
- €75–370
Flights from Brussels Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 5h 25m
- When
- Saturday
- Estimated price
- €75–370
Flights from Brussels South Charleroi Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €60–180
Flights from Brussels South Charleroi Airport to Catania–Fontanarossa Airport via Pisa
- Ave. Duration
- 4h 10m
- When
- Thursday
- Estimated price
- €60–180
Flights from Brussels South Charleroi Airport to Catania–Fontanarossa Airport via Milan Bergamo
- Ave. Duration
- 4h 45m
- When
- Monday, Tuesday, and Sunday
- Estimated price
- €60–180
Flights from Brussels Airport to Malta International Airport via Rome
- Ave. Duration
- 5h 17m
- When
- Thursday to Saturday
- Estimated price
- €70–200
Flights from Brussels South Charleroi Airport to Malta International Airport
- Ave. Duration
- 2h 49m
- When
- Every day
- Estimated price
- €55–170
Flights from Brussels South Charleroi Airport to Malta International Airport via Catania–Fontanarossa Airport
- Ave. Duration
- 5h 25m
- When
- Monday and Friday
- Estimated price
- €55–170
Flights from Brussels South Charleroi Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Monday to Saturday
- Estimated price
- €50–240
Flights from Brussels South Charleroi Airport to Palermo Airport via Pisa
- Ave. Duration
- 4h 22m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- €50–240
Flights from Brussels South Charleroi Airport to Palermo Airport via Turin
- Ave. Duration
- 5h 35m
- When
- Sunday
- Estimated price
- €50–240
Flights from Eindhoven Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 3h
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- €80–260
Flights from Eindhoven Airport to Catania–Fontanarossa Airport via Bologna
- Ave. Duration
- 4h 45m
- When
- Friday
- Estimated price
- €80–260
Flights from Eindhoven Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 5h 15m
- When
- Wednesday, Saturday, and Sunday
- Estimated price
- €80–260
Flights from Eindhoven Airport to Catania–Fontanarossa Airport via Pisa
- Ave. Duration
- 4h 55m
- When
- Monday and Friday
- Estimated price
- €80–260
Flights from Eindhoven Airport to Catania–Fontanarossa Airport via Milan Bergamo
- Ave. Duration
- 5h 10m
- When
- Monday and Sunday
- Estimated price
- €80–260
- Website
- klm.com
Flights from Amsterdam Airport Schiphol to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 50m
- When
- Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- €85–420
Flights from Amsterdam Airport Schiphol to Catania–Fontanarossa Airport via Milan Linate
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- €70–230
- Website
- ita-airways.com
Flights from Brussels Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- €75–230
Flights from Brussels Airport to Malta International Airport via Rome
- Ave. Duration
- 5h 55m
- When
- Every day
- Estimated price
- €70–270
Flights from Brussels Airport to Malta International Airport via Milan Linate
- Ave. Duration
- 6h 50m
- When
- Monday to Saturday
- Estimated price
- €75–160
- Website
- brusselsairlines.com
Flights from Brussels Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Saturday
- Estimated price
- €70–250
Flights from Brussels Airport to Malta International Airport
- Ave. Duration
- 2h 55m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €75–160
- Website
- aeroitalia.com
Flights from Brussels Airport to Vincenzo Magliocco Airport via Milan Linate
- Ave. Duration
- 6h 25m
- When
- Monday to Saturday
- Estimated price
- €150–420
Flights from Brussels Airport to Vincenzo Magliocco Airport via Rome
- Ave. Duration
- 7h 10m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €100–390
- Website
- flexflight.dk
Flights from Brussels Airport to Vincenzo Magliocco Airport via Milan Linate
- Ave. Duration
- 6h 25m
- When
- Monday to Saturday
- Estimated price
- €150–420
Flights from Brussels Airport to Vincenzo Magliocco Airport via Rome
- Ave. Duration
- 7h 10m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €100–390
- Website
- swiss.com
Flights from Brussels Airport to Malta International Airport via Zurich
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- €75–310
- Website
- transavia.com
Flights from Amsterdam Airport Schiphol to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 50m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- €85–420
- Website
- tuifly.be
Flights from Brussels Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 3h 5m
- When
- Saturday
- Estimated price
- €50–190
- Website
- easyjet.com
Flights from Brussels Airport to Catania–Fontanarossa Airport via Geneva
- Ave. Duration
- 5h 15m
- When
- Wednesday
- Estimated price
- €70–390
- Website
- flyulendo.com
Flights from Brussels Airport to Vincenzo Magliocco Airport via Tirana
- Ave. Duration
- 5h 25m
- When
- Friday
- Estimated price
- €130–430
- Website
- airmalta.com
Flights from Brussels Airport to Malta International Airport
- Ave. Duration
- 2h 55m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €75–160
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Brussel-Zuid / Bruxelles-Midi to Aeroport Cdg2 Tgv Roissy
- Ave. Duration
- 1h 43m
- Frequency
- Every 3 hours
- Estimated price
- €40–90
- Website
- https://www.sncf-connect.com/en-en
Train from Aeroport Cdg2 Tgv Roissy to Torino Porta Susa
- Ave. Duration
- 5h 53m
- Frequency
- 3 times a week
- Estimated price
- €120–270
- Website
- https://www.sncf-connect.com/en-en
Train from Chambery Challes Les Eaux to Torino Porta Nuova
- Ave. Duration
- 2h 51m
- Frequency
- Twice a week
- Estimated price
- €60–170
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +44 343 218 6186
- Website
- eurostar.com
Train from Brussel-Zuid / Bruxelles-Midi to Aeroport Cdg2 Tgv Roissy
- Ave. Duration
- 1h 16m
- Frequency
- 4 times a week
- Estimated price
- €45–120
- Website
- https://www.eurostar.com/rw-en
Train from Brussel-Zuid / Bruxelles-Midi to Schiphol Airport
- Ave. Duration
- 1h 37m
- Frequency
- Hourly
- Estimated price
- €35–120
- Website
- https://www.eurostar.com/rw-en
Train from Brussel-Zuid / Bruxelles-Midi to Paris Nord
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- €55–150
- Website
- https://www.eurostar.com/rw-en
Train from Brussel-Zuid / Bruxelles-Midi to Chambery Challes Les Eaux
- Ave. Duration
- 4h 11m
- Frequency
- 3 times a week
- Estimated price
- €120–300
- Website
- https://www.eurostar.com/rw-en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Torino Porta Susa to Villa S.Giovanni
- Ave. Duration
- 10h 31m
- Frequency
- Twice daily
- Estimated price
- €110–340
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Torino Porta Susa to Villa S.Giovanni
- Ave. Duration
- 10h 22m
- Frequency
- Twice a week
- Estimated price
- €95–190
- Website
- https://www.italotreno.it/en
Train from Milano Centrale to Napoli Centrale
- Ave. Duration
- 4h 33m
- Frequency
- Hourly
- Estimated price
- €50–140
- Website
- https://www.italotreno.it/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Palermo Centrale to Caltanissetta Xirbi
- Ave. Duration
- 1h 29m
- Frequency
- Every 3 hours
- Estimated price
- €8–13
- Website
- https://www.trenitalia.com/en.html
Train from Caltanissetta Xirbi to Comiso
- Ave. Duration
- 2h 12m
- Frequency
- Twice daily
- Estimated price
- €10–15
- Website
- https://www.trenitalia.com/en.html
Train from Paris Gare De Lyon to Milano Centrale
- Ave. Duration
- 6h 38m
- Frequency
- Twice daily
- Estimated price
- €60–150
- Website
- https://www.trenitalia.com/en.html
Train from Siracusa to Comiso
- Ave. Duration
- 2h 34m
- Frequency
- 3 times a day
- Estimated price
- €9–14
- Website
- https://www.trenitalia.com/en.html
Train from Torino Porta Nuova to Siracusa
- Ave. Duration
- 22h 10m
- Frequency
- 3 times a week
- Estimated price
- €80–120
- Website
- https://www.trenitalia.com/en.html
- Phone
- +32 70 79 79 79
- Website
- belgiantrain.be
Train from Bruxelles-Central to Breda
- Ave. Duration
- 1h 29m
- Frequency
- Hourly
- Estimated price
- €10–15
- Website
- https://www.belgiantrain.be/en
- 2nd Class
- €10–15
- 1st Class
- €16–23
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Bruxelles-Central to Breda
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €17–55
- Website
- https://www.ns.nl/en
- 2nd Class
- €17–26
- 1st Class
- €30–55
Train from Breda to Eindhoven
- Ave. Duration
- 39 min
- Frequency
- Every 30 minutes
- Estimated price
- €14
- Website
- https://www.ns.nl/en
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact Details
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Brussel-Zuid / Bruxelles-Midi to Paris Nord
- Ave. Duration
- 3h 3m
- Frequency
- 3 times a day
- Estimated price
- €50–120
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- 2nd Class
- €50–75
- Rail 1st Class
- €80–120
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Napoli Centrale to Siracusa
- Ave. Duration
- 8h 53m
- Frequency
- Once daily
- Estimated price
- €30–85
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 164160
- info@etnatrasporti.it
- Website
- etnatrasporti.it
Bus from Catania Fontanarossa Airport Bus Stop to Gela Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- €6–8
- Schedules at
- etnatrasporti.it
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Villa San Giovanni-Piazza Stazione to Gela Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- €9–13
- Schedules at
- autoservizisalemi.it
Bus from Bologna Centrale to Gela Bus Station
- Ave. Duration
- 16h 45m
- Frequency
- 5 times a week
- Estimated price
- €40–60
- Schedules at
- autoservizisalemi.it
- Phone
- +393293958604
- info@pistoiaviaggi.com
- Website
- pistoia-viaggi.it
Bus from Brussels-North Station to Bologna
- Ave. Duration
- 17h 10m
- Frequency
- Once a week
- Schedules at
- pistoia-viaggi.it
- info@flibco.com
- Website
- flibco.com
Bus from Brussels Midi / Brussels South West to Charleroi Airport
- Ave. Duration
- 55 min
- Frequency
- Every 30 minutes
- Estimated price
- €15–20
- Website
- https://www.flibco.com/en
- Phone
- (+356) 22069022
- res@virtuferries.com
- Website
- virtuferries.com
Busferry from Valletta to Pozzallo
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- €73
- Website
- https://www.virtuferries.com/
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Brussels-North train station to Milano, Autostazione Lampugnano
- Ave. Duration
- 12h 25m
- Frequency
- Once daily
- Estimated price
- €45–110
- Website
- https://www.flixbus.co.uk
Bus from Milano, Autostazione Lampugnano to Catania Airport
- Ave. Duration
- 19h 35m
- Frequency
- Twice daily
- Estimated price
- €65–190
- Website
- https://www.flixbus.co.uk
Bus from Catania Airport to Comiso
- Ave. Duration
- 3h 38m
- Frequency
- Once daily
- Estimated price
- €15–22
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Milano, Autostazione Lampugnano to Catania Airport
- Ave. Duration
- 20h 10m
- Frequency
- Twice daily
- Estimated price
- €50–200
- Website
- https://www.itabus.it/en/home
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €60–140
- Website
- https://www.gnv.it/en
- Ave. Duration
- 51 min
- Estimated price
- €80–100
Walk Around Sicily
- Phone
- +39 335 800 4210
- Website
- walkaroundsicily.com
Taxi Modica H24
- Phone
- +39 392 102 7894
- Website
- taximodica.it
Taxi Pozzallo
- Phone
- +3909321846960, +393358004210
- Website
- taxipozzallo.com
Taxi - N.C.C. Autonoleggio Ragusa
- Phone
- +39 333 991 0777
- Website
- iviaggidellisola.com
Radio Taxi Libero
- Phone
- +39 334 100 0344
- Website
- digilander.libero.it
Cisa NCC Taxi
- Phone
- +39 320 673 4244
Walk Around Sicily
- Phone
- +39 335 800 4210
- Website
- walkaroundsicily.com
Taxi Modica H24
- Phone
- +39 392 102 7894
- Website
- taximodica.it
Taxi Pozzallo
- Phone
- +3909321846960, +393358004210
- Website
- taxipozzallo.com
Taxi - N.C.C. Autonoleggio Ragusa
- Phone
- +39 333 991 0777
- Website
- iviaggidellisola.com
Radio Taxi Libero
- Phone
- +39 334 100 0344
- Website
- digilander.libero.it
Cisa NCC Taxi
- Phone
- +39 320 673 4244
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More Questions & Answers
Brussels to Comiso bus services, operated by FlixBus, arrive at Milano, Autostazione Lampugnano station.
Brussels to Comiso train services, operated by Eurostar, arrive at Paris Nord station.
Book your Brussels to Comiso train tickets online with Omio.
Book your Brussels to Comiso bus tickets online with FlixBus.
There are 1784+ hotels available in Comiso.


































































