There are 11 ways to get from Brussels to Comiso by plane, bus, train, car, car ferry, train (Trenitalia), or train (Eurostar, TGV, Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Brussels Airport to Catania–Fontanarossa Airport, bus
best- Fly from Brussels Airport (BRU) to Catania–Fontanarossa Airport (CTA)plane BRU - CTA
- Take the bus from Catania Fontanarossa Airport Bus Stop to Gela Bus Stationbus
8h 36m€89–303Bus to Brussels South Charleroi Airport, fly to Catania–Fontanarossa Airport, bus
cheapest- Take the bus from Brussels Midi / Brussels South West to Charleroi Airportbus
- Fly from Brussels South Charleroi Airport (CRL) to Catania–Fontanarossa Airport (CTA)plane CRL - CTA
- Take the bus from Catania Fontanarossa Airport Bus Stop to Gela Bus Stationbus
9h 20m€82–214Train, bus
- Take the train from Brussel-Zuid / Bruxelles-Midi to Aeroport Cdg2 Tgv Roissytrain Tgv
- Take the train from Aeroport Cdg2 Tgv Roissy to Torino Porta Susatrain Tgv
- Take the train from Torino Porta Susa to Villa S.Giovannitrain Fr
- Take the bus from Villa San Giovanni-Piazza Stazione to Gela Bus Stationbus
26h 22m€241–714Drive, car ferry
- Drive from Brussels to Port of Genoacar
- Take the car ferry from Port of Genoa to Port of Palermocarferry
- Drive from Port of Palermo to Comisocar
34h 31m€246–415Bus
- Take the bus from Brussels-North Station to Bolognabus
- Take the bus from Bologna Centrale to Gela Bus Stationbus Autoservizi Salemi S121 / ...
36h 55mFly Brussels Airport to Vincenzo Magliocco Airport
- Fly from Brussels Airport (BRU) to Vincenzo Magliocco Airport (CIY)plane BRU - CIY
7h 44m€99–342Train, train to Eindhoven Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Bruxelles-Central to Bredatrain
- Take the train from Breda to Eindhoventrain
- Fly from Eindhoven Airport (EIN) to Catania–Fontanarossa Airport (CTA)plane EIN - CTA
- Take the bus from Catania Fontanarossa Airport Bus Stop to Gela Bus Stationbus
11h 39m€97–404Bus to Brussels South Charleroi Airport, fly to Palermo Airport, train
- Take the bus from Brussels Midi / Brussels South West to Charleroi Airportbus
- Fly from Brussels South Charleroi Airport (CRL) to Palermo Airport (PMO)plane CRL - PMO
- Take the train from Palermo Centrale to Caltanissetta Xirbitrain
- Take the train from Caltanissetta Xirbi to Comisotrain
12h 28m€93–323Train via Rome
- Take the train from Brussel-Zuid to Paris Nordtrain
- Take the train from Paris Gare De Lyon to Milano Centraletrain Fr
- Take the train from Milano Centrale to Roma Terminitrain Fr / ...
- Take the train from Roma Termini to Siracusatrain Ic
- Take the train from Siracusa to Comisotrain Re
28h 25m€187–534Train
- Take the train from Brussel-Zuid / Bruxelles-Midi to Chambery Challes Les Eauxtrain
- Take the train from Chambery Challes Les Eaux to Torino Porta Nuovatrain Tgv
- Take the train from Torino Porta Nuova to Siracusatrain
- Take the train from Siracusa to Comisotrain Re
35h 44m€273–549Bus via Milan
- Take the bus from Brussels-North train station to Milano, Autostazione Lampugnanobus
- Take the bus from Milano, Autostazione Lampugnano to Catania Airportbus
- Take the bus from Catania Airport to Comisobus
37h 28m€100–291
Brussels to Comiso by train and bus
Questions & Answers
The cheapest way to get from Brussels to Comiso is to bus and fly which costs €80 - €220 and takes 9h 20m.
The fastest way to get from Brussels to Comiso is to fly which takes 7h 44m and costs €95 - €350.
No, there is no direct bus from Brussels station to Comiso. However, there are services departing from Brussels-North Station and arriving at Comiso via Bologna Centrale and Gela. The journey, including transfers, takes approximately 36h 55m.
No, there is no direct train from Brussels to Comiso. However, there are services departing from Brussel-Zuid and arriving at Comiso via Paris Nord, Paris Gare De Lyon, Milano Centrale, Roma Termini and Siracusa. The journey, including transfers, takes approximately 28h 25m.
The distance between Brussels and Comiso is 1858 km.
The best way to get from Brussels to Comiso without a car is to train and bus which takes 26h 22m and costs €240 - €750.
It takes approximately 8h 36m to get from Brussels to Comiso, including transfers.
Brussels to Comiso bus services, operated by FlixBus, depart from Brussels-North train station.
Brussels to Comiso train services, operated by Nederlandse Spoorwegen (NS), depart from Brussel-Zuid station.
The best way to get from Brussels to Comiso is to bus which takes 36h 55m and costs . Alternatively, you can fly, which costs €95 - €350 and takes 7h 44m, you could also train via Rome, which costs €180 - €550 and takes 28h 25m.
What companies run services between Brussels, Belgium and Comiso, Italy?
You can take a bus from Brussels-North Station to Comiso via Bologna Centrale and Gela in around 36h 55m. Alternatively, TUI fly Belgium, Ulendo Airlink, and four other airlines fly from Brussels Airport (BRU) to Vincenzo Magliocco Airport (CIY) twice daily.
- Website
- ryanair.com
Flights from Brussels Airport to Catania–Fontanarossa Airport via Pisa
- Ave. Duration
- 4h 20m
- When
- Tuesday
- Estimated price
- €70–370
Flights from Brussels Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 5h 25m
- When
- Sunday
- Estimated price
- €70–370
Flights from Brussels South Charleroi Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €60–170
Flights from Brussels South Charleroi Airport to Catania–Fontanarossa Airport via Milan Bergamo
- Ave. Duration
- 4h 53m
- When
- Monday, Friday, and Sunday
- Estimated price
- €60–170
Flights from Eindhoven Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 3h
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- €60–300
Flights from Eindhoven Airport to Catania–Fontanarossa Airport via Milan Bergamo
- Ave. Duration
- 4h 50m
- When
- Monday, Friday, and Sunday
- Estimated price
- €60–300
Flights from Eindhoven Airport to Catania–Fontanarossa Airport via Bologna
- Ave. Duration
- 4h 45m
- When
- Friday
- Estimated price
- €60–300
Flights from Eindhoven Airport to Catania–Fontanarossa Airport via Pisa
- Ave. Duration
- 4h 55m
- When
- Monday and Friday
- Estimated price
- €60–300
Flights from Brussels South Charleroi Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- €50–270
Flights from Brussels South Charleroi Airport to Palermo Airport via Turin
- Ave. Duration
- 6h
- When
- Friday
- Estimated price
- €50–270
- Website
- aeroitalia.com
Flights from Brussels Airport to Vincenzo Magliocco Airport via Milan Linate
- Ave. Duration
- 6h 25m
- When
- Monday to Saturday
- Estimated price
- €130–390
Flights from Brussels Airport to Vincenzo Magliocco Airport via Rome
- Ave. Duration
- 7h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €80–320
Flights from Brussels Airport to Vincenzo Magliocco Airport via Bologna, Rome
- Ave. Duration
- 11h 25m
- When
- Monday, Friday, and Sunday
- Estimated price
- €80–320
- Website
- flexflight.dk
Flights from Brussels Airport to Vincenzo Magliocco Airport via Milan Linate
- Ave. Duration
- 6h 25m
- When
- Monday to Saturday
- Estimated price
- €130–390
Flights from Brussels Airport to Vincenzo Magliocco Airport via Rome
- Ave. Duration
- 7h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €80–320
Flights from Brussels Airport to Vincenzo Magliocco Airport via Bologna, Rome
- Ave. Duration
- 11h 25m
- When
- Monday, Friday, and Sunday
- Estimated price
- €80–320
- Website
- brusselsairlines.com
Flights from Brussels Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Saturday
- Estimated price
- €60–250
Flights from Brussels Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- €75–230
- Website
- ita-airways.com
Flights from Brussels Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- €75–230
Flights from Brussels Airport to Catania–Fontanarossa Airport via Milan Linate
- Ave. Duration
- 5h 30m
- When
- Monday to Saturday
- Estimated price
- €75–230
- Website
- tuifly.be
Flights from Brussels Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 3h 5m
- When
- Saturday
- Estimated price
- €75–260
- Website
- swiss.com
Flights from Brussels Airport to Catania–Fontanarossa Airport via Geneva
- Ave. Duration
- 5h 30m
- When
- Monday
- Estimated price
- €65–270
- Website
- flyulendo.com
Flights from Brussels Airport to Vincenzo Magliocco Airport via Tirana
- Ave. Duration
- 5h 25m
- When
- Friday
- Estimated price
- €100–340
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Brussel-Zuid / Bruxelles-Midi to Aeroport Cdg2 Tgv Roissy
- Ave. Duration
- 1h 43m
- Frequency
- Every 3 hours
- Estimated price
- €30–90
- Website
- https://www.sncf-connect.com/en-en
Train from Aeroport Cdg2 Tgv Roissy to Torino Porta Susa
- Ave. Duration
- 5h 53m
- Frequency
- Twice a week
- Estimated price
- €120–250
- Website
- https://www.sncf-connect.com/en-en
Train from Chambery Challes Les Eaux to Torino Porta Nuova
- Ave. Duration
- 2h 51m
- Frequency
- Twice a week
- Estimated price
- €60–170
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +44 343 218 6186
- Website
- eurostar.com
Train from Brussel-Zuid / Bruxelles-Midi to Aeroport Cdg2 Tgv Roissy
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a week
- Estimated price
- €35–120
- Website
- https://www.eurostar.com/rw-en
Train from Brussel-Zuid / Bruxelles-Midi to Chambery Challes Les Eaux
- Ave. Duration
- 4h 11m
- Frequency
- 3 times a week
- Estimated price
- €120–250
- Website
- https://www.eurostar.com/rw-en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Torino Porta Susa to Villa S.Giovanni
- Ave. Duration
- 10h 29m
- Frequency
- Twice daily
- Estimated price
- €100–330
- Schedules at
- trenitalia.com
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €45–110
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Torino Porta Susa to Villa S.Giovanni
- Ave. Duration
- 10h 22m
- Frequency
- Twice a week
- Estimated price
- €75–150
- Website
- https://www.italotreno.it/en
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 39m
- Frequency
- Hourly
- Estimated price
- €45–100
- Website
- https://www.italotreno.it/en
- Phone
- +32 70 79 79 79
- Website
- belgiantrain.be
Train from Bruxelles-Central to Breda
- Ave. Duration
- 1h 29m
- Frequency
- Hourly
- Estimated price
- €10–15
- Website
- https://www.belgiantrain.be/en
- 2nd Class
- €10–15
- 1st Class
- €16–23
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Bruxelles-Central to Breda
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €13–65
- Website
- https://www.ns.nl/en
Train from Breda to Eindhoven
- Ave. Duration
- 39 min
- Frequency
- Every 30 minutes
- Estimated price
- €13–15
- Website
- https://www.ns.nl/en
Train from Brussel-Zuid to Paris Nord
- Ave. Duration
- 1h 23m
- Frequency
- Every 2 hours
- Estimated price
- €45–160
- Website
- https://www.ns.nl/en
- 2nd Class
- €45–70
- 1st Class
- €95–160
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Palermo Centrale to Caltanissetta Xirbi
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- €12
- Website
- https://www.trenitalia.com/en.html
Train from Caltanissetta Xirbi to Comiso
- Ave. Duration
- 2h 12m
- Frequency
- Twice daily
- Estimated price
- €10–15
- Website
- https://www.trenitalia.com/en.html
Train from Paris Gare De Lyon to Milano Centrale
- Ave. Duration
- 6h 42m
- Frequency
- Twice daily
- Estimated price
- €55–150
- Website
- https://www.trenitalia.com/en.html
Train from Siracusa to Comiso
- Ave. Duration
- 2h 34m
- Frequency
- 3 times a day
- Estimated price
- €12
- Website
- https://www.trenitalia.com/en.html
Train from Torino Porta Nuova to Siracusa
- Ave. Duration
- 23h 8m
- Frequency
- Once a week
- Estimated price
- €80–120
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Siracusa
- Ave. Duration
- 11h 12m
- Frequency
- Once daily
- Estimated price
- €26–100
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 164160
- info@etnatrasporti.it
- Website
- etnatrasporti.it
Bus from Catania Fontanarossa Airport Bus Stop to Gela Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- €6–8
- Schedules at
- etnatrasporti.it
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Villa San Giovanni-Piazza Stazione to Gela Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- €9–14
- Schedules at
- autoservizisalemi.it
Bus from Bologna Centrale to Gela Bus Station
- Ave. Duration
- 16h 45m
- Frequency
- 5 times a week
- Estimated price
- €45–70
- Schedules at
- autoservizisalemi.it
- Phone
- +393293958604
- info@pistoiaviaggi.com
- Website
- pistoia-viaggi.it
Bus from Brussels-North Station to Bologna
- Ave. Duration
- 17h 10m
- Frequency
- Once a week
- Schedules at
- pistoia-viaggi.it
- info@flibco.com
- Website
- flibco.com
Bus from Brussels Midi / Brussels South West to Charleroi Airport
- Ave. Duration
- 55 min
- Frequency
- Every 30 minutes
- Estimated price
- €16–20
- Website
- https://www.flibco.com/en
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Brussels-North train station to Milano, Autostazione Lampugnano
- Ave. Duration
- 12h 25m
- Frequency
- Once daily
- Estimated price
- €45–110
- Website
- https://www.flixbus.co.uk
Bus from Milano, Autostazione Lampugnano to Catania Airport
- Ave. Duration
- 19h 25m
- Frequency
- Twice daily
- Estimated price
- €40–130
- Website
- https://www.flixbus.co.uk
Bus from Catania Airport to Comiso
- Ave. Duration
- 3h 38m
- Frequency
- Once daily
- Estimated price
- €15–22
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Milano, Autostazione Lampugnano to Catania Airport
- Ave. Duration
- 20h 10m
- Frequency
- Twice daily
- Estimated price
- €40–160
- Website
- https://www.itabus.it/en/home
- Phone
- +39 010 209 4591
- booking@gnv.it
- Website
- gnv.it
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €60–140
- Website
- https://www.gnv.it/en
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More Questions & Answers
Brussels to Comiso bus services, operated by FlixBus, arrive at Milano, Autostazione Lampugnano station.
Brussels to Comiso train services, operated by Nederlandse Spoorwegen (NS), arrive at Paris Nord station.
Book your Brussels to Comiso train tickets online with Omio.
Book your Brussels to Comiso bus tickets online with FlixBus.
There are 1730+ hotels available in Comiso.





























































