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How to get fromBrussels to Comisoby bus, plane, train, car, car ferry, train (Eurostar, Trenitalia) or train (Eurostar, TGV, Trenitalia)

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There are 11 ways to get from Brussels to Comiso by bus, plane, train, car, car ferry, train (Eurostar, Trenitalia), or train (Eurostar, TGV, Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Brussels South Charleroi Airport, fly to Vincenzo Magliocco Airport

    best
    1. Take the bus from Brussels Midi / Brussels South West to Charleroi Airportbus bus
    2. Fly from Brussels South Charleroi Airport (CRL) to Vincenzo Magliocco Airport (CIY)plane plane CRL - CIY
    13h 33m
    €74–276

  2. Bus to Brussels South Charleroi Airport, fly to Catania–Fontanarossa Airport, bus

    cheapest
    1. Take the bus from Brussels Midi / Brussels South West to Charleroi Airportbus bus
    2. Fly from Brussels South Charleroi Airport (CRL) to Catania–Fontanarossa Airport (CTA)plane plane CRL - CTA
    3. Take the bus from Aeroporto Vincenzo Bellini/Fontanarossa to Ragusa Bus Terminalbus bus
    10h 1m
    €68–208

  3. Train, bus

    1. Take the train from Brussel-Zuid / Bruxelles-Midi to Aeroport Cdg2 Tgv Roissytrain train Tgv
    2. Take the train from Aeroport Cdg2 Tgv Roissy to Torino Porta Susatrain train Tgv
    3. Take the train from Torino Porta Susa to Villa S.Giovannitrain train Fr
    4. Take the bus from Villa San Giovanni-Piazza Stazione to Gela Bus Stationbus bus
    26h 36m
    €328–736

  4. Drive, car ferry

    1. Drive from Brussels to Port of Genoacar car
    2. Take the car ferry from Port of Genoa to Port of Palermocarferry car ferry
    3. Drive from Port of Palermo to Comisocar car
    34h 31m
    €256–435

  5. Bus

    1. Take the bus from Brussels-North Station to Bolognabus bus
    2. Take the bus from Bologna Centrale to Gela Bus Stationbus bus Autoservizi Salemi S121 / ...
    36h 55m

  6. Fly Brussels Airport to Catania–Fontanarossa Airport, bus

    1. Fly from Brussels Airport (BRU) to Catania–Fontanarossa Airport (CTA)plane plane BRU - CTA
    2. Take the bus from Aeroporto Vincenzo Bellini/Fontanarossa to Ragusa Bus Terminalbus bus
    9h 19m
    €93–304

  7. Fly Brussels Airport to Vincenzo Magliocco Airport

    1. Fly from Brussels Airport (BRU) to Vincenzo Magliocco Airport (CIY)plane plane BRU - CIY
    8h 46m
    €94–362

  8. Bus to Brussels South Charleroi Airport, fly to Palermo Airport, train

    1. Take the bus from Brussels Midi / Brussels South West to Charleroi Airportbus bus
    2. Fly from Brussels South Charleroi Airport (CRL) to Palermo Airport (PMO)plane plane CRL - PMO
    3. Take the train from Palermo Centrale to Caltanissetta Xirbitrain train
    4. Take the train from Caltanissetta Xirbi to Comisotrain train
    12h 28m
    €81–287

  9. Train via Rome

    1. Take the train from Brussel-Zuid / Bruxelles-Midi to Paris Nordtrain train
    2. Take the train from Paris Gare De Lyon to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Roma Terminitrain train Fr / ...
    4. Take the train from Roma Termini to Siracusatrain train Ic
    5. Take the train from Siracusa to Comisotrain train Re
    28h 28m
    €257–582

  10. Train

    1. Take the train from Brussel-Zuid / Bruxelles-Midi to Chambery Challes Les Eauxtrain train
    2. Take the train from Chambery Challes Les Eaux to Torino Porta Nuovatrain train Tgv
    3. Take the train from Torino Porta Nuova to Siracusatrain train
    4. Take the train from Siracusa to Comisotrain train Re
    35h 44m
    €290–531

  11. Bus via Milan

    1. Take the bus from Brussels-North train station to Milanbus bus
    2. Take the bus from Milano, Autostazione Lampugnano to Catania Airportbus bus
    3. Take the bus from Catania Airport to Comisobus bus
    37h 28m
    €151–262

Brussels to Comiso by train

Calendar8Weekly Trains
Duration28h 28mAverage Duration
Ticket€257Cheapest Price
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Questions & Answers

What companies run services between Brussels, Belgium and Comiso, Italy?

You can take a bus from Brussels-North Station to Comiso via Bologna Centrale and Gela in around 36h 55m. Alternatively, Brussels Airlines, FlexFlight ApS, and Aeroitalia fly from Brussels Airport (BRU) to Vincenzo Magliocco Airport (CIY) twice daily.

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