There are 6 ways to get from Brno to Karlovy Vary by bus, train, night train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  5 h 12 min

  1. Take the bus from Brno, AN u hotelu Grand to Praha, ÚAN Florenc Rj / ...
  2. Take the bus from Prague, Prague ÚAN Florenc to Karlovy Vary, Karlovy Vary - Tržnice 854 / ...

$14 - $32

5 alternative options

Train, bus  •  5 h 32 min

  1. Take the train from Brno hlavní nádraží to Praha hlavní nádraží
  2. Take the bus from Prague, Prague ÚAN Florenc to Karlovy Vary, Karlovy Vary - Tržnice 854 / ...

$16 - $26

Train RegioJet  •  6 h 49 min

  1. Take the train from Brno hlavní nádraží to Praha hlavní nádraží
  2. Take the train from Praha hl.n. to Karlovy Vary Regional

$19 - $29

Train via Praha-Liben  •  7 h 43 min

  1. Take the train from Brno hl.n. to Praha-Liben Regional / ...
  2. Take the train from Praha hl.n. to Karlovy Vary Regional

$19 - $29

Night train, bus  •  6 h 33 min

  1. Take the night train from Brno hlavní nádraží to Praha-Libeň Metropol
  2. Take the bus from Praha Hradčanská to Karlovy Vary tržnice Leo Express

$19 - $27

Drive  •  3 h 35 min

  1. Drive from Brno to Karlovy Vary 210.2 miles

$35 - $55

What companies run services between Brno, Czech Republic and Karlovy Vary, Czech Republic?

You can take a bus from Brno to Karlovy Vary via Praha, ÚAN Florenc and Prague, Prague ÚAN Florenc in around 5 h 12 min. Alternatively, you can take a train from Brno to Karlovy Vary via Praha hlavní nádraží and Praha hl.n. in around 6 h 49 min.

Train operators
RegioJet
Phone
+420 542 42 42 42
Email
info@regiojet.cz
Website
regiojet.sk
Train from Brno hlavní nádraží to Praha hlavní nádraží
Ave. Duration
2 h 33 min
Frequency
Every 4 hours
Estimated price
$10 - $14
Schedules at
regiojet.sk
Czech Railways (ČD)
Phone
+420 221 111 122
Email
info@cd.cz
Website
cd.cz
Train from Praha hl.n. to Karlovy Vary
Ave. Duration
3 h 16 min
Frequency
Every 2 hours
Estimated price
$9 - $15
Website
cd.cz
Train from Brno hl.n. to Praha-Liben
Ave. Duration
3 h 11 min
Frequency
Hourly
Estimated price
$10 - $15
Website
cd.cz
Hungarian Railways (MÁV)
Bus operators
RegioJet
Phone
+420 542 42 42 42
Email
info@regiojet.cz
Website
regiojet.sk
Bus from Brno, AN u hotelu Grand to Praha, ÚAN Florenc
Ave. Duration
2 h 30 min
Frequency
Every 30 minutes
Estimated price
$7 - $10
Schedules at
regiojet.sk
FlixBus
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Brno, Brno Hotel Grand to Prague, Prague ÚAN Florenc
Ave. Duration
2 h 35 min
Frequency
Every 4 hours
Estimated price
$12 - $20
Website
flixbus.co.uk
Bus from Prague, Prague ÚAN Florenc to Karlovy Vary, Karlovy Vary - Tržnice
Ave. Duration
2 h 5 min
Frequency
Hourly
Estimated price
$7 - $12
Website
flixbus.co.uk
Leo Express s.r.o.
Phone
+420 220 311 700
Email
info@le.cz
Website
leoexpress.com
Bus from Brno hotel Grand to Praha ÚAN Florenc
Ave. Duration
2 h 35 min
Frequency
Every 2 hours
Estimated price
$8 - $11
Schedules at
leoexpress.com
Economy
$8 - $11
Bus from Praha ÚAN Florenc to Karlovy Vary tržnice
Ave. Duration
2 h 5 min
Frequency
Every 4 hours
Estimated price
$6 - $8
Schedules at
leoexpress.com
Economy
$6 - $8
Bus from Praha Hradčanská to Karlovy Vary tržnice
Ave. Duration
1 h 45 min
Frequency
Every 4 hours
Estimated price
$6 - $8
Schedules at
leoexpress.com
Economy
$6 - $8
Tour Bus
Website
tourbus.cz
Bus from Brno - Benešova to Praha, ÚAN Florenc
Ave. Duration
2 h 35 min
Frequency
Once daily
Estimated price
$6 - $23
Schedules at
tourbus.cz

Want to know more about travelling around Czechia

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Questions & Answers

The distance between Brno and Karlovy Vary is 292 km. The road distance is 336 km.

The cheapest way to get from Brno to Karlovy Vary is to bus which costs 290 Kč - 700 Kč and takes 5 h 12 min.

The quickest way to get from Brno to Karlovy Vary is to drive which takes 3 h 35 min and costs 800 Kč - 1 200 Kč.

No, there is no direct train from Brno to Karlovy Vary. However, there are services departing from Brno hlavní nádraží and arriving at Karlovy Vary via Praha hl.n.. The journey, including transfers, takes approximately 6 h 49 min.

No, there is no direct bus from Brno to Karlovy Vary. However, there are services departing from Brno, AN u hotelu Grand and arriving at Karlovy Vary, Karlovy Vary - Tržnice via Prague, Prague ÚAN Florenc. The journey, including transfers, takes approximately 5 h 12 min.

It takes approximately 5 h 12 min to get from Brno to Karlovy Vary, including transfers.