Transport NSW operates a train from Brisbane to Kempsey once daily. Tickets cost $45 - $70 and the journey takes 6 h 48 min. Alternatively, Greyhound Australia operates a bus from Brisbane to Kempsey twice daily. Tickets cost $40 - $80 and the journey takes 11 h 45 min. Transport NSW also services this route twice daily.
From Central, platform 3 train to Brisbane airport, fly to Port Macquarie airport, then bus to Kempsey. 3 h 58 min $149. From Brisbane train to Kempsey Station. 6 h 48 min $67. From Brisbane Roma Street bus to Kooloonbung Creek Nature Park, Gordon St then bus to Belgrave St At John St. 13 h 38 min $67. From Brisbane drive to Kempsey. 5 h 53 min $54.