There are 8 ways to get from Brig to Siena by bus, train, car, plane, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Domodossola to Rho Fiera Milanobus Re4
- Take the train from Milano Rogoredo to Bologna centraletrain
- Take the train from Bologna Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
7h 5mBus
cheapest- Take the bus from Domodossola - Stazione Ferroviaria to Aeroporto Malpensa - Terminal 1bus 3
- Take the bus from Milan Malpensa Airport 1 P13 to Siena Central Train Stationbus Itabus
10h 39m€40–60Bus via Florence
- Take the bus from Domodossola to Milano Centralebus Re4
- Take the bus from Milano - Famagosta to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Sienabus 443 / ...
10h 13mDrive 549.4 km
- Drive from Brig to Sienacar 549.4 km
5h 53m€99–143Bus to Milano Malpensa Airport, fly to Florence Peretola Airport, train
- Take the bus from Domodossola - Stazione Ferroviaria to Aeroporto Malpensa - Terminal 1bus
- Fly from Milano Malpensa Airport (MXP) to Florence Peretola Airport (FLR)plane MXP - FLR
- Take the train from Firenze S.M.N. to Sienatrain
9h 17m€140–288Train (Trenitalia)
- Take the train from Domodossola to Rho-Fiera Milanotrain Re
- Take the train from Rho-Fiera Milano to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
8h 50m€72–121Train, train to Zurich Airport, fly to Florence Peretola Airport
- Take the train from Brig to Berntrain
- Take the train from Bern to Zürich Flughafentrain
- Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane ZRH - FLR
- Take the train from Firenze S.M.N. to Sienatrain
8h 11m€191–425Train, train to Zurich Airport, fly to Bologna Guglielmo Marconi Airport
- Take the train from Brig to Berntrain
- Take the train from Bern to Zürich Flughafentrain
- Fly from Zurich Airport (ZRH) to Bologna Guglielmo Marconi Airport (BLQ)plane ZRH - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
8h 41m€188–455
Milano Malpensa Airport (MXP) to Florence Peretola Airport (FLR) flights
Comparing Your Travel Options
The cheapest way to get from Brig to Siena is to bus which costs €40 - €60 and takes 10h 39m.
The fastest way to get from Brig to Siena is to drive which takes 5h 53m and costs €95 - €150.
No, there is no direct bus from Brig to Siena. However, there are services departing from Domodossola and arriving at Siena via Milano, Stazione Centrale, Milano - Famagosta and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 10h 13m.
No, there is no direct train from Brig to Siena. However, there are services departing from Brig and arriving at Siena via Domodossola, Rho-Fiera Milano and Firenze S.M.N.. The journey, including transfers, takes approximately 8h 50m.
The distance between Brig and Siena is 570 km. The road distance is 549.4 km.
The best way to get from Brig to Siena without a car is to bus and train which takes 7h 5m and costs .
It takes approximately 7h 5m to get from Brig to Siena, including transfers.
Brig to Siena bus services, operated by Trenord, depart from Domodossola station.
Brig to Siena train services, operated by Trenitalia, depart from Domodossola station.
The best way to get from Brig to Siena is to bus via Florence which takes 10h 13m and costs . Alternatively, you can train, which costs €70 - €130 and takes 8h 50m.
What companies run services between Brig, Switzerland and Siena, Italy?
You can take a train from Brig to Siena via Domodossola, Domodossola, Milano Centrale, Milano, Stazione Centrale, famagosta m2, Milano - Famagosta, and Florence Villa Constanza Bus Station in around 10h 13m. Alternatively, you can take a train from Brig to Siena via Domodossola, Rho-Fiera Milano, and Firenze S.M.N. in around 8h 50m.
- Website
- swiss.com
Flights from Milano Malpensa Airport to Florence Peretola Airport via Zurich Airport
- Ave. Duration
- 3h 13m
- When
- Every day
- Estimated price
- €80–320
Flights from Zurich Airport to Florence Peretola Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- €85–340
Flights from Zurich Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €85–430
- Website
- lufthansa.com
Flights from Milano Malpensa Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €150–550
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- €160–550
Flights from Zurich Airport to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 2h 55m
- When
- Every day
- Estimated price
- €140–440
- Website
- airdolomiti.it
Flights from Milano Malpensa Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €150–550
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 5m
- When
- Friday
- Estimated price
- €160–550
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Rogoredo to Bologna centrale
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €26–45
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 38 min
- Frequency
- 5 times a day
- Estimated price
- €11–18
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 38 min
- Frequency
- 5 times a day
- Estimated price
- €11–18
- Website
- Italo Treno
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Milano Rogoredo to Bologna centrale
- Ave. Duration
- 1h 41m
- Frequency
- Every 3 hours
- Estimated price
- €30–55
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 20 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
Train from Rho-Fiera Milano to Firenze S.M.N.
- Ave. Duration
- 2h 22m
- Frequency
- Every 3 hours
- Estimated price
- €40–75
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 20 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Domodossola to Rho-Fiera Milano
- Ave. Duration
- 2h 4m
- Frequency
- Every 2 hours
- Estimated price
- €13–19
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
Train from Brig to Bern
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- €35–55
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Bern to Zürich Flughafen
- Ave. Duration
- 1h 12m
- Frequency
- Hourly
- Estimated price
- €45–65
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Brig to Bern
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- €35–55
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Bern to Zürich Flughafen
- Ave. Duration
- 1h 12m
- Frequency
- Hourly
- Estimated price
- €45–65
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- Trenord
Bus from Domodossola to Rho Fiera Milano
- Ave. Duration
- 1h 25m
- Frequency
- Every 2 hours
- Website
- Trenord
Bus from Domodossola to Milano Centrale
- Ave. Duration
- 1h 40m
- Frequency
- Every 2 hours
- Website
- Trenord
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- Onebus
Bus from Milano - Famagosta to Florence Villa Constanza Bus Station
- Ave. Duration
- 2h 41m
- Frequency
- Once a week
- Estimated price
- €60–85
- Website
- Onebus
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 4 hours
- Estimated price
- €5–9
- Website
- Flixbus
- Phone
- +39 0322 844 862
- comazzi@comazzibus.com
- Website
- Comazzi Bus
Bus from Domodossola - Stazione Ferroviaria to Aeroporto Malpensa - Terminal 1
- Ave. Duration
- 1h 20m
- Frequency
- Every 4 hours
- Estimated price
- €9
- Website
- Comazzi Bus
Bus from Domodossola - Stazione Ferroviaria to Aeroporto Malpensa - Terminal 1
- Ave. Duration
- 1h 20m
- Frequency
- Every 4 hours
- Estimated price
- €9
- Website
- Comazzi Bus
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Milan Malpensa Airport 1 P13 to Siena Central Train Station
- Ave. Duration
- 6h 50m
- Frequency
- Once daily
- Estimated price
- €23–40
- Website
- Itabus S.p.A.
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Booking & Getting There
Brig to Siena bus services, operated by Trenord, arrive at Milano Centrale station.
Brig to Siena train services, operated by Trenitalia, arrive at Rho-Fiera Milano station.
Yes, the driving distance between Brig to Siena is 549 km. It takes approximately 5h 53m to drive from Brig to Siena.
Book your Brig to Siena train tickets online with Omio.
There are 2395+ hotels available in Siena.






























