There are 5 ways to get from Boston to St. Louis (Region) by plane, train (Amtrak), bus (Greyhound, Flixbus), car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Boston Logan Airport (BOS) to Lambert–St. Louis International Airport (STL)plane BOS - STL
3h 38m$287–574Bus
cheapest- Take the bus from Boston to Newark Penn Stationbus Greyhound US0235 / ...
- Take the bus from Newark Penn Station to St Louis Bus Stationbus Greyhound US0421
28h 20m$204–403Train (Amtrak)
- Take the train from Boston to Chicago Union Stationtrain Lake Shore Limited
- Take the train from Chicago Union Station to St. Louistrain Lincoln Service / ...
28h 8m$361–803Drive 1,150.4 mi
- Drive from Boston to St. Louis (Region)car 1,150.4 mi
20h 25m$210–304Bus via New York
- Take the bus from Boston to New York Midtownbus FlixBus 2610 / ...
- Take the bus from Port Authority Bus Terminal to St Louis Bus Stationbus Greyhound US0421
28h 31m$208–387
Boston to St. Louis (Region) by train (Amtrak)
Questions & Answers
The cheapest way to get from Boston to St. Louis (Region) is to bus via New York which costs $200 - $390 and takes 28h 31m.
The fastest way to get from Boston to St. Louis (Region) is to fly which takes 3h 38m and costs $280 - $600.
No, there is no direct bus from Boston to St. Louis (Region) station. However, there are services departing from Boston and arriving at St Louis Bus Station via Newark Penn Station. The journey, including transfers, takes approximately 28h 20m.
No, there is no direct train from Boston to St. Louis (Region). However, there are services departing from Boston and arriving at St. Louis via Chicago Union Station. The journey, including transfers, takes approximately 28h 8m.
The distance between Boston and St. Louis (Region) is 1064 miles. The road distance is 1157.2 miles.
The best way to get from Boston to St. Louis (Region) without a car is to train which takes 28h 8m and costs $360 - $850.
It takes approximately 3h 38m to get from Boston to St. Louis (Region), including transfers.
Boston to St. Louis (Region) bus services, operated by Greyhound USA, depart from Boston station.
Boston to St. Louis (Region) train services, operated by Amtrak, depart from Boston station.
The best way to get from Boston to St. Louis (Region) is to fly which takes 3h 38m and costs $280 - $600. Alternatively, you can train, which costs $360 - $850 and takes 28h 8m, you could also bus, which costs $200 - $410 and takes 28h 20m.
What companies run services between Boston, MA, USA and St. Louis (Region), MO, USA?
American Airlines, Southwest Airlines, and Delta fly from Boston Logan Airport (BOS) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a train from Boston to St. Louis via Chicago Union Station in around 28h 8m.
- Website
- southwest.com
Flights from Boston Logan Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 56m
- When
- Every day
- Estimated price
- $170–850
Flights from Boston Logan Airport to Lambert–St. Louis International Airport via Baltimore
- Ave. Duration
- 5h 38m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $180–900
Flights from Boston Logan Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 5h 22m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $180–900
- Website
- aa.com
Flights from Boston Logan Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 3h 12m
- When
- Every day
- Estimated price
- $170–850
- Website
- delta.com
Flights from Boston Logan Airport to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 5h 12m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $170–900
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Chicago Union Station
- Ave. Duration
- 22h 22m
- Frequency
- Once daily
- Estimated price
- $280–650
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $75–180
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Boston to Newark Penn Station
- Ave. Duration
- 4h 50m
- Frequency
- 5 times a day
- Estimated price
- $40–85
- Website
- https://www.greyhound.com/
Bus from Newark Penn Station to St Louis Bus Station
- Ave. Duration
- 22h 30m
- Frequency
- Once daily
- Estimated price
- $170–320
- Website
- https://www.greyhound.com/
Bus from Port Authority Bus Terminal to St Louis Bus Station
- Ave. Duration
- 23h
- Frequency
- 3 times a day
- Estimated price
- $180–340
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Boston to Newark Penn Station
- Ave. Duration
- 4h 35m
- Frequency
- 4 times a day
- Estimated price
- $30–60
- Schedules at
- flixbus.com
Bus from Boston to New York Midtown
- Ave. Duration
- 4h 20m
- Frequency
- Hourly
- Estimated price
- $28–50
- Schedules at
- flixbus.com
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More Questions & Answers
Boston to St. Louis (Region) bus services, operated by Greyhound USA, arrive at Newark Penn Station.
St. Louis (Region) is 1h behind Boston. It is currently 3:15 AM in Boston and 2:15 AM in St. Louis (Region).
Boston to St. Louis (Region) train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Boston to St. Louis (Region) is 1157 miles. It takes approximately 20h 25m to drive from Boston to St. Louis (Region).
Book your Boston to St. Louis (Region) train tickets online with Omio.
Book your Boston to St. Louis (Region) bus tickets online with Omio and FlixBus.
There are 540+ hotels available in St. Louis (Region).